Basic Information

Transcription Factor Domain

TF Family: PC4
Domain: PC4 domain
PFAM: PF02229
TF Group: Unclassified Structure
Description: This domain is found at the C-terminal end of Activated RNA polymerase II transcriptional coactivator p15 from humans, YdbC from Lactococcus lactis, and other PC4 family members. p15 has a bipartite structure composed of an N-terminal regulatory domain and a carboxy-terminal cryptic DNA-binding domain [1-4]. Activity is controlled by protein kinases that target the regulatory domain.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.002 40 4.9 0.0 10 26 3 19 2 26 0.88

2 5 0.0014 28 5.4 0.0 10 27 25 42 21 49 0.86

3 5 0.0024 46 4.7 0.0 11 26 48 63 44 70 0.89

4 5 0.002 39 4.9 0.0 10 26 69 85 66 89 0.89

5 5 0.00065 13 6.5 0.0 10 25 91 106 79 114 0.62

#	of	c-Evalue	i-Evalue	score	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.002	40	4.9	10	26	3	19	2	26	0.88
2	5	0.0014	28	5.4	10	27	25	42	21	49	0.86
3	5	0.0024	46	4.7	11	26	48	63	44	70	0.89
4	5	0.002	39	4.9	10	26	69	85	66	89	0.89
5	5	0.00065	13	6.5	10	25	91	106	79	114	0.62

Coding Sequence: ATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGACTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCACCATGGCTCAGATGAGGGAGTATAATGACTTCAATAAGCACGTCGGAGGAATAACTTGGATCACATCATGCACTTCCTGTGAATGTGACcagggccgtatttacgccTAG
Protein Sequence: MAQMREYNDFTMAQMREYNDFTMAQMREYNDFTMAQMREYNDFTMTQMREYNDFTMAQMREYNDFTMAQMREYNDFTMAQMREYNDFTMAQMREYNDFTMAQMREYNDFNKHVGGITWITSCTSCECDQGRIYA

Sequence clustering based on sequence similarity using MMseqs2