Basic Information

Gene Symbol
-
Assembly
GCA_907164805.1
Location
OU015467.1:5959132-5974606[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.16 14 7.3 0.3 2 23 178 200 177 200 0.94
2 20 6 5.3e+02 2.3 1.2 1 21 203 223 203 226 0.77
3 20 0.27 24 6.6 0.4 3 23 254 275 253 275 0.96
4 20 3.9 3.4e+02 2.9 0.3 1 12 304 315 304 317 0.82
5 20 0.021 1.9 10.0 0.5 3 23 418 439 416 439 0.91
6 20 0.28 25 6.5 0.7 1 23 442 469 442 469 0.91
7 20 1 93 4.7 1.1 1 23 1045 1068 1045 1068 0.84
8 20 0.0059 0.52 11.8 1.0 1 23 1076 1099 1076 1099 0.98
9 20 0.0026 0.23 12.9 3.8 1 23 1139 1162 1139 1162 0.96
10 20 5.3 4.7e+02 2.5 1.5 3 23 1170 1191 1168 1191 0.92
11 20 0.0098 0.86 11.1 2.9 1 23 1199 1222 1199 1222 0.95
12 20 0.0023 0.2 13.1 1.3 1 23 1228 1250 1228 1250 0.95
13 20 8e-06 0.00071 20.8 1.0 2 23 1257 1278 1256 1278 0.97
14 20 1.3e-07 1.2e-05 26.4 2.5 1 23 1283 1305 1283 1305 0.98
15 20 0.0003 0.027 15.9 4.4 1 23 1311 1333 1311 1333 0.99
16 20 3.1e-05 0.0028 19.0 4.8 2 23 1340 1361 1339 1361 0.96
17 20 5.8e-05 0.0051 18.1 0.5 3 23 1369 1389 1367 1389 0.96
18 20 0.00057 0.05 15.0 0.1 3 23 1397 1418 1396 1418 0.95
19 20 1.5e-05 0.0013 19.9 1.4 1 23 1424 1446 1424 1446 0.98
20 20 0.0013 0.11 13.9 0.8 2 23 1453 1475 1452 1475 0.94

Sequence Information

Coding Sequence
ATGAGCCAGAATAACGGGTTAGAAGAATATGTCGGTCGGACAAGCTATGACCTTTACCACCCAAAGAAGAGTAAGGTTACAGAACCAGACACGACTGCAAGTGAGAGAAATTCTAGAGATGGAATCCATGACAGCGATGGATCGGATAATGAAGAAAGCTTACAGAAAATATTGGAAAATGCAGAGGAGGAAGAAGAAAGAGAAATATTTGATTCCAAACTGACTTCCAACAATCAATCAAATACTGTTGGTATGAACTTCCAAATTCCACAATTATCTGCCTTTTTACAACCTCAGTTACAAGCAATCCCAGTTCCGGCTTCCATCATGATACCTTATACATCACGATCCACCGAGGCAAAGTTATTTGCGGCAAAACAGGCTTGTATTTTAAATTCTTCTGATCCTGCAGTTTCACGGATCAATCTTGAGCCTATTGTGGGAACCATTATTGAATCATCCTCACAAATTTCCTTACAAGCCTCAAAAATCCGAGTAAAATCAAAGGAGGAATCGGGTACAAAGCCGTTGAAGTGCTCTGTTTGCCAAGAGTGGTTTTTTTCAAATGATAAATTAACCATTCACTTAATTTCGAATCATGGAAAACACCACTGCAGTTACTGCGAAGAAATGTTTGAAACTGATTCCGTGAGAGAAGACCACGAAAAGGACATTCATTTTCCTTTAGAATGCGACATTTGTGGTGCTTCTGTTGATAATTTGGATGAACATTATGAAGAAACACATGATATGAGAAATTGTAGATATTGTGGTGTTTTAGTAAAGCCAAAGTCATATTACCAAGTCCACGTAAGAAGAAAGCACTTTGTAAACTGTTTGGAAGCATTAGAGGAGAGAGACGTTCGACTGGTAGGCAATTGGTCACATAGTTCTGACCCGACATGGAATTTCAACTGTCATTTGTGCGGCAAAGAGCGAAAGCGTGCAGACATTCTAGGACATTTCTTTTCGTACCATCGTTTGAGTCTCATGTGTTTAATAGTTTTTCTACGTACCGAACAGATGTTGTTCAGCGTGCAAGGTTCTTTGGCTCCATCTGGTGTTCACCACATGTATACACAAGACACGTCAACAGACGATTCTTCCAAAACATCTCAACATTCAGAGATCTCAACAAGCACAACGTCTGACGACATTCAAAACCGCTTCGATTGCACCTCATGTACAAAACCATTCACGTTCCAAGTGCCAAAACCCGCCCACGATATCATCTGCTGCGGTCTCACTATTTGTCGTTATTGTAGCAAAACGTTCGCCGACAAAGATACGAGAAATCTCCATTTGGAAGAAGACCACGTCAGCTTCCCGTGTACACGAGGTTGCGACAAAACGACGTATACGTTCACCCGGGATTCCGAGCTGCAAGAACATTACAACGAGACTCACTCGGAGATGACGTGCCGTTTCTGTGAAGACTTTCTTCCCAACAACGTGCTGAATCTGGCCGAACATATGAAATCGAAACACACTGCTTCGAGTCGAAGCAAGGCACTGCAAGACAAGGATATTGATCTGCTACAGTTGAATCCCAAGACTGGGTTTTACATGTGTTCCTTGTGTAACGCTGTGACGTCGACCATTAACAACTTGGATGCTGTGTGTAAGCATCTCCAGCATCATAACATCTCGCTGGTAGCTGTTCTCGATATGCTCGAGTCGTATCAGAGTACTGCCGGTAGCGTGCTTAGAGAGCAAGCTCAACCTGGAACAACGCAAATGAACGCGTTGCTACAAGATATACCTAAGAACGAAAATGCGAGTGGTGGGAAAAAAACGAAGAAACGTGCGATGAAAAAAGAGAAGATCCCCAAGAAGCTTGGCCGTGCAGCTGGAGCTAAGAAATCTAAAGCAAACTCTAAACGAAACATGTCTGTGGAAAATTCAGGTGAAGAGAATGGGTGTGAAGAAAGAGAAACGGTTATTAAAGGTTGCTCAAAAGAAACCAAAAGAAATGTTGATAATACGGGTGACTTGGGGTCCAGTCATGAAATCTGCGATACTAACGATAATACTGGCGTGGCGGAAGATTTGACTCTTCGTCCGAACTCGTCGTGCGATTCAACTACGGAAGAAGAAGAATTTGGGTCGGATGTCGCAGGTAACTCGTCAGACGAAGATGAGGAGACGTTGAGGGATGCGTTGGAGAAAATGTCGAAGGGTGACATAATTATCGAAAACGATTTGGGCGAGGCCGAAATTGATCCGACCGAAATCGAATGTGTCATCGACGATACATCCGACGACGAAGAATACAACACCGACGACACTAATTCTGATCTACAGTTCGAAGTGAAGCAAGAACGGTTTGAAATGAACGAAAATCTGAATTCCAATTTGCTGGATATTCAAGAAATGGACAGCGAAAATGATGTAGGAAACTTGGATCAAAACTTCCGAGAAACTGTTCTTAAATGCTGTACCGATAAGAATGTGGACAAAACATTGGACATAATAGAACGTACAATGGAAGATATGTTTCACGAAGCCCCAAAACAATCTCTCGAGTGGAATAACCACCGCATGGACACCGAAGAAGGAATCAACAACGATAATGTTATCGAAACTGATCCGAGTAGTTCCATTGAAGAGGGATCAGATTCAAAAGAAAACCTAAATGCCTTGAACAACCATAATAACCACAAACCCAATAACAAAAGTATACCTCAAACTGATGAAGTCAATAAAATTTCTAATAAAACAAATATGTTGAAGGCTAAAAACGATGTCAATAGTTTCGAAGGTAGACTGAAAAACATCAAGCCCGATCCCGAACAGAATAAAACGGTCGAACAGGTTTTCAACTCGATACTCAAATGCGAACTTTGCACAAAAGTAATATGCGTTTTAAAGTCGCCATTCGAATACGTGGAGCACATGAAAATGTATCACAAGTTTGCCATCTCGGCTCACTGCTCCAAATTCGACGACGCTTCCAACAACGGTTCTTCCGACGAGCTGGAAAACGTCCGTCCGGACAACAATGCTTCCGAAAAAGTGTTCCAGTGCCCGTTCTGTGCCATCCGATCGGTTTGGAAGACGTCGATACGGCAGCACGTGTTCGAGACCCACCCGTCCGACTGCGCCGTCGAACTGCCGTCGGACGGTCTGGGCTACCGCTGCCGGTACTGCAACGAGACGTTCTGGCGAGTCACTGAACGGAACGAGCACCAGATCAACAAACACGATGACCAGATCTTCGAGTACTACAAATGCTACATCTGTTCGCAGATTTCGTCGAGCAAGCTGATGCTGACTCGGCACTTGAAGGTGTCGCACCCTGCCGAGGCTCAGTACGCCGCCGTCTCGTACAAGTGCAAGCTGTGCCTGCTGACGTACCCGTGCCTGCGCTCGCTGCGGGATCACTTCACCGCCACGCACCCGGGCGCCATGGTCTTCCCCTGCCAGCACTGCAACATCACGCTCAAGAACAAGAAGACGCTCAAGACGCACCTCAAGAACATGCACGCGGTGGGTCGGCGCATGGACTGCACGCTCTGCGGCAAGATGCTGTTCAGCAAGCGCGCGCACGCCATCCACTACCGCATGAAGCACAGCCAGGCGTCCAAGGTCGGCTTCCGCTGTCGGATCTGTCACCGTCGCTTCGACACCAAGGACGACCGGAAGATGCACTACGCGGTGGACCACCTGGGAGAGTCTCCGTACCACTGCACCGAGTGCGGGAAGGGGTTCGCCTCCAAGTCGGGCATGTACGGCCACAAGCAGCTCCACACCGGCTCCGGAGTGTCCAAGTGCCAGTACTGCGGCAAGGAGTTCACGCGCAAGGACAGCTACAACGAGCACTTGTTGATCCACAACGGGCCGCGCCACAAGTGTCCGCACTGCCCCAAGGAGTTCGTCCAGAGGTCAAATCTCGTCCGACACATCAGGATACATACAGGAGAGAAGCCGTACAAGTGCGTGTACTGCGACAAGTGCTTCTCCGACAAGGGCGCGTGCAACTCCCACATCCGCGTCCACACGCGCGAGGAGACCTGCAGCTGTCCCTACTGCGGGCAGACGTTCTCCAAGAAACAGAAACTGAAATATCACATACGAAAACACACGGGCGAGGGTTTGATCAACTGCGAAATCTGCACCAAGTCGTTCACAAACAGCTTTGCGCTGAAGGAGCACCGTCTGATCCACAACCGCGAGACGTCCATCTTGTGCGGCGTGTGCGGCAAGGGTTTCAACAGCGAGAAGTACCTGCAGCGACACGTGGCCATCGTGCACGAGCCACAGCAGACCTTCAACTGCCCCCTGTGCTCGAAGGTGTTCTCGCAGCAGACGCGCCTGAAGAGCCACCTGATGACCCACACGGGTGTCAAGCACATGAAGTGCCTGCTCTGCGACAAGGCGTACTCGGTGCGCAAGTCCCTTCGCCGCCACCTGCTCGAGAAGCACCAGGTCTCTCCCGACCACCCGCAGTACAAGCGCTGTTTCTACGCCATGACGCACCAGGAGGCGGGGCTTCAGATCCCCGACGACATGTCCTACTTCGCGGCCACCTTCGACGACGACTCCACCACGCACTCCCTCACCAGAGACGACGACGTCAAGCCGCAGGGCAAGAGGTCGCCGAGGAAGTCCGGGAAGAAACCCGTTTATATCGATCCCGACGAGGAGGCGGTTGCGAAGAAGCCGCGGAGGAAGACGCCGACGAAGAAAGCGCTCGCGGGGAAGACCGATTCAACGTCGCACCAAGATAAGCCGTCGACTTCCAAACAAGATAAGAAAGGAGCGAAGAAGTTATCGAACAAACTGTCGGCGGAGAAGAGTCCGGACGATTCCAGTTCGGGCATCTCGGACGATTCCATATCGTCGGACGACGGCGCGAAGATGAAGAAGGGTATTTCGAACATAGTGGAGCGCTTGCAGAAACGTCTGGGACCGGGGAAGAAGAAGCGGAGAGTGGAGGCGATCGTGGAGACGCTGCAGAAGAGCTCGACGGGGTCTCCGAGCACGAACCAGGACGACAGCACCGCGGAGCCGAGCGACAACGACGAGCCGGTGCTGGCGCGGATCCACTCGTTGAACAGTCCGAAGAGATCCGGCGTCGGGCGGAGGAACTTGTGCCGCAAGCCCGTGCCCGAGAGGATCCCGCGCAAGGACAGGTCCGACGACGACTCGAGCTGA
Protein Sequence
MSQNNGLEEYVGRTSYDLYHPKKSKVTEPDTTASERNSRDGIHDSDGSDNEESLQKILENAEEEEEREIFDSKLTSNNQSNTVGMNFQIPQLSAFLQPQLQAIPVPASIMIPYTSRSTEAKLFAAKQACILNSSDPAVSRINLEPIVGTIIESSSQISLQASKIRVKSKEESGTKPLKCSVCQEWFFSNDKLTIHLISNHGKHHCSYCEEMFETDSVREDHEKDIHFPLECDICGASVDNLDEHYEETHDMRNCRYCGVLVKPKSYYQVHVRRKHFVNCLEALEERDVRLVGNWSHSSDPTWNFNCHLCGKERKRADILGHFFSYHRLSLMCLIVFLRTEQMLFSVQGSLAPSGVHHMYTQDTSTDDSSKTSQHSEISTSTTSDDIQNRFDCTSCTKPFTFQVPKPAHDIICCGLTICRYCSKTFADKDTRNLHLEEDHVSFPCTRGCDKTTYTFTRDSELQEHYNETHSEMTCRFCEDFLPNNVLNLAEHMKSKHTASSRSKALQDKDIDLLQLNPKTGFYMCSLCNAVTSTINNLDAVCKHLQHHNISLVAVLDMLESYQSTAGSVLREQAQPGTTQMNALLQDIPKNENASGGKKTKKRAMKKEKIPKKLGRAAGAKKSKANSKRNMSVENSGEENGCEERETVIKGCSKETKRNVDNTGDLGSSHEICDTNDNTGVAEDLTLRPNSSCDSTTEEEEFGSDVAGNSSDEDEETLRDALEKMSKGDIIIENDLGEAEIDPTEIECVIDDTSDDEEYNTDDTNSDLQFEVKQERFEMNENLNSNLLDIQEMDSENDVGNLDQNFRETVLKCCTDKNVDKTLDIIERTMEDMFHEAPKQSLEWNNHRMDTEEGINNDNVIETDPSSSIEEGSDSKENLNALNNHNNHKPNNKSIPQTDEVNKISNKTNMLKAKNDVNSFEGRLKNIKPDPEQNKTVEQVFNSILKCELCTKVICVLKSPFEYVEHMKMYHKFAISAHCSKFDDASNNGSSDELENVRPDNNASEKVFQCPFCAIRSVWKTSIRQHVFETHPSDCAVELPSDGLGYRCRYCNETFWRVTERNEHQINKHDDQIFEYYKCYICSQISSSKLMLTRHLKVSHPAEAQYAAVSYKCKLCLLTYPCLRSLRDHFTATHPGAMVFPCQHCNITLKNKKTLKTHLKNMHAVGRRMDCTLCGKMLFSKRAHAIHYRMKHSQASKVGFRCRICHRRFDTKDDRKMHYAVDHLGESPYHCTECGKGFASKSGMYGHKQLHTGSGVSKCQYCGKEFTRKDSYNEHLLIHNGPRHKCPHCPKEFVQRSNLVRHIRIHTGEKPYKCVYCDKCFSDKGACNSHIRVHTREETCSCPYCGQTFSKKQKLKYHIRKHTGEGLINCEICTKSFTNSFALKEHRLIHNRETSILCGVCGKGFNSEKYLQRHVAIVHEPQQTFNCPLCSKVFSQQTRLKSHLMTHTGVKHMKCLLCDKAYSVRKSLRRHLLEKHQVSPDHPQYKRCFYAMTHQEAGLQIPDDMSYFAATFDDDSTTHSLTRDDDVKPQGKRSPRKSGKKPVYIDPDEEAVAKKPRRKTPTKKALAGKTDSTSHQDKPSTSKQDKKGAKKLSNKLSAEKSPDDSSSGISDDSISSDDGAKMKKGISNIVERLQKRLGPGKKKRRVEAIVETLQKSSTGSPSTNQDDSTAEPSDNDEPVLARIHSLNSPKRSGVGRRNLCRKPVPERIPRKDRSDDDSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00243550;
90% Identity
iTF_00243550;
80% Identity
-