Basic Information

Insect: Brachyptera putata
Gene Symbol: Hr39
Assembly: GCA_907164805.1
Location: OU015466.1:23605162-23615184[-]

Transcription Factor Domain

TF Family: SF-like
Domain: zf-C4|SF-like
PFAM: AnimalTFDB
TF Group: Zinc-Coordinating Group
Description: The ligand binding domain of nuclear receptor steroidogenic factor 1 (SF-1): SF-1, a member of the nuclear hormone receptor superfamily, is an essential regulator of endocrine development and function and is considered a master regulator of reproduction. Most nuclear receptors function as homodimer or heterodimers, however SF-1 binds to its target genes as a monomer, recognizing the variations of the DNA sequence motif, T/CCA AGGTCA. SF-1 functions cooperatively with other transcription factors to modulate gene expression. Phospholipids have been determined as potential ligands of SF-1. Like other members of the nuclear receptor (NR) superfamily of ligand-activated transcription factors, SF-1 has a central well conserved DNA binding domain (DBD), a variable N-terminal domain, a flexible hinge and a C-terminal ligand binding domain (LBD). [1, 8, 3, 11, 6, 5, 12, 10, 9, 2, 4, 7]
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 4 0.014 2.5e+02 1.8 3.2 114 170 281 345 201 396 0.66

2 4 1.2e-08 0.00021 21.8 0.0 1 25 553 577 553 607 0.81

3 4 0.0032 56 3.9 0.0 78 133 606 657 578 678 0.66

4 4 3.4e-70 6e-66 224.5 0.3 157 408 613 876 606 876 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	4	0.014	2.5e+02	1.8	3.2	114	170	281	345	201	396	0.66
2	4	1.2e-08	0.00021	21.8	0.0	1	25	553	577	553	607	0.81
3	4	0.0032	56	3.9	0.0	78	133	606	657	578	678	0.66
4	4	3.4e-70	6e-66	224.5	0.3	157	408	613	876	606	876	0.89

Sequence Information

Coding Sequence: ATGGATACGACAACGTTAACTAACAATAGTGTGTCTGTGAACAGTCCGTGGGGGGGTGGCCCCCCTCGGTTTACTCATCAACATTCCAACAATGCCCCGAAGAACAAAGCGACAACGGGGTCGACCGGCGGTGTGATAACTAACTCTGTGATGGAACAGTTGAGGCCCCCAGATACGGGGGGCGGATGTATTAGTAGTGCGGGGTCTTGTAAAGACGATGTGCCCCGGGGGGCGGGACTGGGGGTAGTGACGGCCTCGTCGGGGGCGGTTACCGTTATTAACGTTGGGGCTAGCTCAACGGACAGCTCACATCCGGATGACGGAAAAAATATCAAGTATTATCAAACCTGCAATGGGAGCGTAGTTTCCGAGCAGGACAGCCGAGGCAACTTGTTGCTGGAAGACGACGAAGGGTCGGGATCGGACGGCGAAGTGAGCAAGATCGACTTCAACGGCGTCAACCTGCGCAACAAGAAGAAACGAGCGGCCGCGATGGCCGGAGAAGAGTCTCGCGACAGCTACGTCGAGGAGCCGGAGAGACCCATGTCGTGGGAGGGAGAACTTTCAGACGCGGAGATGAGCGTGGTTACGGGAAGTCTCGACAATAAACAGGACCGAGAGGAAACATCGATGGAAGGAGTACAGATTTGTGGCGTCAACAACATTAACAACACAACGTTGTTGAACAACATCGAGGACAGCAAGCAACCACTCAAGTTCAGAGAAAATGTGGTTGACAAAGTACTGGACCACGTCCGCTCGAAACAGTTCCACCACCAAGCCCCTCTCCCGCCAAACGCCACCACAGAGTTGCCACTCCTCGTCGACAAGCTACTCGGCAACGGCGGCTGCTACATCACCACACCCTCCCACAGTCCCATCCTCCAGCACCGCCACCCCCTCCACCTGAAACACTCGGGCATCCCGCCCACCCCCAGCCCCGACTCGGCGATCCACTCGGCGTACTCATACTCGTCCCCGACCCAGTCGCCCGTCACGTCGCGACACGGCTCGATGACGGGCTTCAGCTCGCCGTACACGCCGTCGTTGTCGCGGAACAACTCGGATGCGTCGCAGTACGGCGGCTCGCAGCACAGCAGCTGTTACAGCTACTCGTCGGTGTCCGTTTCGCCCACGCAGTTCTCGCCAACGCATTCGCCTATCCAGTCGCGCCATATCCATGCTGGATATCCATCGCCCGTAATGCCGCGCGGATCTGACTGCTCCCCCCTCCACGTCATGGGTGCCAACGGTCACATGTACGGGGTACCTCGGGGGCCTCTCGGGGCAGTCGACGAAGCCCTCCTGTTGGACGGGGCTTCCACGGACACCAACGATGAACGGGATGGCGGTGATGACAAGTTGTCCTCCTTGTCCGGAGATCTCGGTCAGCACTCGGCACTGGTAGCGCCTCCTGGTATCTCGAGGCAGCAACTTATCAACAGTCCTTGCCCAATCTGCGGTGACAAGATATCAGGCTTCCATTACGGTATCTTCTCGTGCGAGAGTTGTAAAGGTTTCTTCAAACGTACCGTACAGAATCGCAAGAACTACGTGTGTTTGCGGGGTTCCTCGTGCCCGGTAACCATAGCAACTAGAAAGAAATGTCCAGCATGTCGCTTTGAAAAGTGCCTGAAAATGGGCATGAAATTAGAAGCCATTCGAGAAGATCGTACCCGCGGCGGTCGAAGTACGTACCAATGTTCGTACACGCTGCCGCCCAGCTTGGTTGCACCGTCCGGTAGCGATCACATGAAGCTACTCGCCCCCTCTGGTGATCCCCAGGTGAAACTGGAGGCACCAGATTTGGGGGCAATCGCGGGCAGCAGCGGTGAAAGCCAATCACCGCATTCGAGACATGCGGAGAAGACGGCGGTCCCTCAGTTATTACAAGAAATAATGGATGTGGAGCACCTATGGCACTACAACGAGTCGGAGGCACAGAAGATGTCGTCGGCGCACGGCAGCAATCACCACGGCAACGGCAGCGGCCCGAGCAACGGCAACACGAGCAGCAGCCGAGTACCGAGCAATAACCCAGACTTCCTATCAAACTTGTGTAACATTGCTGACCATAGACTGTACAGGCTCGTCAAGTGGTGCAAGAGTTTGCCGCTCTTCAAGAATATATCGATTGACGATCAAATCTCCCTCCTGATCAATGCCTGGTGCGAGCTGTTGTTATTCTCGTGTTGCTTCCGCTCAATGTGTTCACCGGGTGAGATCCGAGTCAGCCTCGGCAAGTCCATCACTCTTGCTCAGGCCCGTGACTTGGGACTCGGTGCCTGCATCGAACGTATGCTCAACTTCACCGAGCACCTCAGGCGGCTCAGGGTGGACAAGTACGAGTATGTTGCCATGAAAGTCATTGTTCTTCTTACTTCAGATGCCAACGACTTGCGAGAATGCGAGAAAGTGCGCGCGTCCCAAGAGAAGGCGCTAGAAGCGCTGCAGCACTACACACTCGCACATTATCCAGATATCCCGTCCAAGTTCGGCGAATTGCTCTTGAGAATTCCAGAACTACAGCGCACGTGTCAGGTTGGTAAGGAGATGTTATCAATAAAGAACAAAGAAGGTGAAGGTCCTAGCTTCAATCTACTGATGGAGTTACTACGAGGTGACCATTAA
Protein Sequence: MDTTTLTNNSVSVNSPWGGGPPRFTHQHSNNAPKNKATTGSTGGVITNSVMEQLRPPDTGGGCISSAGSCKDDVPRGAGLGVVTASSGAVTVINVGASSTDSSHPDDGKNIKYYQTCNGSVVSEQDSRGNLLLEDDEGSGSDGEVSKIDFNGVNLRNKKKRAAAMAGEESRDSYVEEPERPMSWEGELSDAEMSVVTGSLDNKQDREETSMEGVQICGVNNINNTTLLNNIEDSKQPLKFRENVVDKVLDHVRSKQFHHQAPLPPNATTELPLLVDKLLGNGGCYITTPSHSPILQHRHPLHLKHSGIPPTPSPDSAIHSAYSYSSPTQSPVTSRHGSMTGFSSPYTPSLSRNNSDASQYGGSQHSSCYSYSSVSVSPTQFSPTHSPIQSRHIHAGYPSPVMPRGSDCSPLHVMGANGHMYGVPRGPLGAVDEALLLDGASTDTNDERDGGDDKLSSLSGDLGQHSALVAPPGISRQQLINSPCPICGDKISGFHYGIFSCESCKGFFKRTVQNRKNYVCLRGSSCPVTIATRKKCPACRFEKCLKMGMKLEAIREDRTRGGRSTYQCSYTLPPSLVAPSGSDHMKLLAPSGDPQVKLEAPDLGAIAGSSGESQSPHSRHAEKTAVPQLLQEIMDVEHLWHYNESEAQKMSSAHGSNHHGNGSGPSNGNTSSSRVPSNNPDFLSNLCNIADHRLYRLVKWCKSLPLFKNISIDDQISLLINAWCELLLFSCCFRSMCSPGEIRVSLGKSITLAQARDLGLGACIERMLNFTEHLRRLRVDKYEYVAMKVIVLLTSDANDLRECEKVRASQEKALEALQHYTLAHYPDIPSKFGELLLRIPELQRTCQVGKEMLSIKNKEGEGPSFNLLMELLRGDH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00242312; iTF_00894898; iTF_00894830;
90% Identity: iTF_00242312;
80% Identity: iTF_00242312;