Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.23 5.8e+02 2.1 0.1 11 45 65 97 60 104 0.77

2 5 0.067 1.7e+02 3.8 0.0 22 52 102 132 94 134 0.76

3 5 0.017 43 5.7 0.2 23 48 131 156 125 160 0.85

4 5 0.00016 0.41 12.2 0.0 22 53 158 189 152 190 0.90

5 5 2.7e-05 0.07 14.7 0.3 21 43 185 207 183 215 0.91

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.23	5.8e+02	2.1	0.1	11	45	65	97	60	104	0.77
2	5	0.067	1.7e+02	3.8	0.0	22	52	102	132	94	134	0.76
3	5	0.017	43	5.7	0.2	23	48	131	156	125	160	0.85
4	5	0.00016	0.41	12.2	0.0	22	53	158	189	152	190	0.90
5	5	2.7e-05	0.07	14.7	0.3	21	43	185	207	183	215	0.91

Coding Sequence: ATGGGCGATGAAATTAATTCAGTAAATGTAGAAGTTGAACCAGATGTAATTTTAGATGTAGACTCGGATGAATCGGACGAAGACAGCAGCAGtgattctgtagaaaaatttgaaacatttcgAACAAAATTAGTGGCGAACGGATTCAGTGGAATGTACGACACTGGAATAATGAATGCGCTGATAAAGGACGGAGTCACAAAGCCGATTGATTCAAATCGGCTCGAACAATGTGCCGAATGTGGTAAATATTATCGTCGTCTGGCACGTCACATGATGAAACATATGAACAGTGAAGATTATGAGAAAAATTTAACCTGTCAACTTTGCTATGAAAAATTTGCTTCAAAAGATTTGCTTgaagcacatttaaaaaatcacAATGGATGTAAACCGTTTGTGTGTGATATTTGTAAAAAGGCATTCGCACAgaattgtaatttaattaatcataTTCGAGTCCATACCGGGGATAAACCCTTTAAATGCCATTTGTGCGATAAACGATTCACACAGTcgggtaatttaaaaaatcatttacgATTGCATAATGATGAGAAACCGTACGTTTGTTCGATTTGTTATCAGAGTTTTCGACAACTTTCCAATTTGAATAATCATAGTAAGAAACATCCAAATTTTAAAGAGAGTCCATTTAAACGGGCTAAAGTTATTTCGATATCAAGTTAA
Protein Sequence: MGDEINSVNVEVEPDVILDVDSDESDEDSSSDSVEKFETFRTKLVANGFSGMYDTGIMNALIKDGVTKPIDSNRLEQCAECGKYYRRLARHMMKHMNSEDYEKNLTCQLCYEKFASKDLLEAHLKNHNGCKPFVCDICKKAFAQNCNLINHIRVHTGDKPFKCHLCDKRFTQSGNLKNHLRLHNDEKPYVCSICYQSFRQLSNLNNHSKKHPNFKESPFKRAKVISISS

Sequence clustering based on sequence similarity using MMseqs2