Basic Information

Insect: Brachynemurus nebulosus
Gene Symbol: -
Assembly: GCA_035578155.1
Location: JAPWDM010000023.1:3393480-3395009[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 0.00032 0.017 16.9 0.8 2 23 130 151 129 151 0.96

2 13 0.0002 0.011 17.6 1.2 1 23 157 179 157 179 0.97

3 13 0.00026 0.014 17.2 0.8 1 23 185 207 185 207 0.98

4 13 7.2e-05 0.0039 18.9 0.9 1 23 213 235 213 235 0.98

5 13 1.2e-07 6.6e-06 27.7 0.6 1 23 241 263 241 263 0.98

6 13 0.00019 0.01 17.6 0.2 1 23 269 291 269 291 0.98

7 13 3.7e-06 0.0002 23.0 1.1 1 23 297 319 297 319 0.99

8 13 0.0023 0.12 14.2 3.2 1 23 334 356 334 356 0.98

9 13 2.2e-05 0.0012 20.6 4.5 1 23 362 384 362 384 0.99

10 13 0.00011 0.0063 18.3 0.9 1 23 390 412 390 412 0.96

11 13 2.4e-05 0.0013 20.4 1.5 1 23 418 440 418 440 0.98

12 13 3.8e-05 0.0021 19.8 3.2 1 23 446 468 446 468 0.98

13 13 2.8e-06 0.00015 23.4 1.3 1 23 474 496 474 496 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	0.00032	0.017	16.9	0.8	2	23	130	151	129	151	0.96
2	13	0.0002	0.011	17.6	1.2	1	23	157	179	157	179	0.97
3	13	0.00026	0.014	17.2	0.8	1	23	185	207	185	207	0.98
4	13	7.2e-05	0.0039	18.9	0.9	1	23	213	235	213	235	0.98
5	13	1.2e-07	6.6e-06	27.7	0.6	1	23	241	263	241	263	0.98
6	13	0.00019	0.01	17.6	0.2	1	23	269	291	269	291	0.98
7	13	3.7e-06	0.0002	23.0	1.1	1	23	297	319	297	319	0.99
8	13	0.0023	0.12	14.2	3.2	1	23	334	356	334	356	0.98
9	13	2.2e-05	0.0012	20.6	4.5	1	23	362	384	362	384	0.99
10	13	0.00011	0.0063	18.3	0.9	1	23	390	412	390	412	0.96
11	13	2.4e-05	0.0013	20.4	1.5	1	23	418	440	418	440	0.98
12	13	3.8e-05	0.0021	19.8	3.2	1	23	446	468	446	468	0.98
13	13	2.8e-06	0.00015	23.4	1.3	1	23	474	496	474	496	0.98

Sequence Information

Coding Sequence: atgGAAGAAAATAACGATTTTGTACCAGTTCATGAAACGgtttatattaaatttgatcCAGAAGAAAGtctttttaaaactgaaacagaGGAAAATTCGCCAGTTACAAGTAATTGTTTTACCAACAAAATAAAACAGGGATCTTTTGAATCTCTTAATGAAAATTCCATGAAATTCGATGATTTGAAAAAGGAACGAGGTAACATAAGTGATCCATTGTTTTCGGGAACTTTACCTGTTCAAGTTAAAATTGAAACTAatgatgaaaattataaaaaatttgaattttttcccGAACAGTCTGTTAAAAAGGAATCGAAAAAAATACATGACAGaactgttttgagaaaaaaacataaaaaagttCGCACGGAAGAAAAATCACTCGAATGCAATGTatgcttaaaaaaatatgctagtttATCAAATTTAAGAACACATAAGAAAATTCACACGGGCGAGAGAGATTTTCAGTGCATTACTTGCTCGAAAACTTTTACCCAAGCAATagctttaaaaaaacatgaaagaactcATACGGGAGAAAAACCTTTTGAGTGtagtacatgttttaaaacatatgtagACAAGTCTGTCCtaaaaattcatgaaagaaTCCACACcggagaaaaaccatacaaatgtgcCACATGTTTCAAAGCATTTATTAAATCATCACAATTAAGGGTTCATGAGAAAATTCACACTGGTGAAAAGAATTTCAAATGCAATATTTGCTCCAAAGCATTTACTCAATCATCGGGCCTCAGACGACATATACTAAttcatacaggagaaaaaccttATGAATGCGATATATGTCTTAGAAAATTTGCCGATGGATCAGACCTTGTAAAACATAAACGAATCCACACAGGAGAAAGACCTTataagtgtaatatatgtttgaaAACATTCAGTCGTAGTCCACTTTTGAAGCAGCATGAAAGAGTTCACACGGGAGAAAAACCAGAAAAGAAGGAAAAACCAGAAAAACAATTCGAATGTAGTATATGTTTCCGAAAATTTGTCCACATACGCAGTTTAAAGGATCACGAGAAAACCCATACGGATGAAAAACATTTCAAATGCACCGTTTGCTTTAAATCATTTATTAAATCGGCACATTTGAGGCGGCATACACTAACTCACACGGGTGAAAAACCTCATGAGTGCAGTATATGTCTTAGAAAATTTGCCGATAGGTCAGATCTGAAAAAGCATGAAATAATTCACACGGGAGAGAGACCTTTTAAATGCAACTTATGCTTAAAAGCATTCAATCGTTCAGTGACACTAAAGAAACATGAAAGAGTTCATACGGGCGAAAAACCATTCGAATGTAGTATATGTTTCAGAAAATTCGGTCAATCATCACATTTGCGAGATCATGAGAGAACTCATACAGGTGAAAAAGCTTTTAGTTGTAATATTTGTCTGAAAACTTTTACCCAGTCAGGAAGTTTaagaaaacatgaaagaattcatgaAGAAGAAATGCTCGATATTGCTAACATAATGAATGAATGA
Protein Sequence: MEENNDFVPVHETVYIKFDPEESLFKTETEENSPVTSNCFTNKIKQGSFESLNENSMKFDDLKKERGNISDPLFSGTLPVQVKIETNDENYKKFEFFPEQSVKKESKKIHDRTVLRKKHKKVRTEEKSLECNVCLKKYASLSNLRTHKKIHTGERDFQCITCSKTFTQAIALKKHERTHTGEKPFECSTCFKTYVDKSVLKIHERIHTGEKPYKCATCFKAFIKSSQLRVHEKIHTGEKNFKCNICSKAFTQSSGLRRHILIHTGEKPYECDICLRKFADGSDLVKHKRIHTGERPYKCNICLKTFSRSPLLKQHERVHTGEKPEKKEKPEKQFECSICFRKFVHIRSLKDHEKTHTDEKHFKCTVCFKSFIKSAHLRRHTLTHTGEKPHECSICLRKFADRSDLKKHEIIHTGERPFKCNLCLKAFNRSVTLKKHERVHTGEKPFECSICFRKFGQSSHLRDHERTHTGEKAFSCNICLKTFTQSGSLRKHERIHEEEMLDIANIMNE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00240321;
90% Identity: iTF_00240321;
80% Identity: iTF_00240321;