Bneb024651.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Brachynemurus nebulosus
Gene Symbol
BTBD7
Assembly
GCA_035578155.1
Location
JAPWDM010000007.1:28231763-28234649[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 2.2e-11 1.2e-08 36.5 0.0 9 97 166 257 158 269 0.73
2 3 3e-06 0.0016 20.0 0.0 22 50 303 333 299 372 0.71
3 3 0.75 4e+02 2.6 0.0 72 107 393 429 385 431 0.88

Sequence Information

Coding Sequence
ATGAACTTGTTTGGGTGTCTGCTGCCATGTTCATTGAAGCGCGGTTGGTGGAACTTTGAAGAGACGGAGAGTAACAACGGAGTGCGCACCGACCTGCTGGCTGCCCCCACAGCGATGGGTGCAAATGCGTCAAATACAGCTGGTGTGTCTGGTGTTTCTGACATGCCGTTACCCCAATCACTGGCCGGAGCCGCTGCAAGCACGGGTGCGTCGTTGTCACAGGACGGTGTCATTGTACGGGAGCGTAAGAAGAAAGTGACCGGTTTCGCGACGTTGCGTAAAAAGTTCATACGGCGTCGCAGATCGTCAAAACCGTGCGATCACGGACGTATGTTGCGTGAACTAGTGGCGGACTGGAGTCCGTTAGAGTTGGCCGCCTTACTGGAGGAGTACGAAGCGTTGGCCGCGTTGAAAGATTTGAGTTTTCAAGCGGAATTGGCCCGACCACCAGCCACCACGTTTAAACAGGATTTAAGTGCACTTtacgattttaaatattgtactGATGCGGATTTAGTGTTTCGTGGCGCTTGTTTTCCAATACATCGTGCATTACTCTCGGCGCGGTGTCCCTATTTTCGTGATTTACTTGCCGGATGTCCGGGCTACGGTGCTCGAATATGTTTAGAATTGAATCGTACAGCTTCGTTAGATGTACAATTATTTTCGGCCCTTTTAAGATATTTATATACTGGTGATATTTGCCCGCATGAAAGTAATATTGACTTAGAGTTATTGCGAAGACTTGGCGAAGAATTTGGAACGCCAAATCCATTGGAGCATGATTTACGATACTTGTTAGAGACGGGTGATTACGCGGACGCGGCATTAGTATTTACTTCCGATGGTAACGATTATCAACGACCGGATTCGGGTAGTTCCGAGTATGGTTTTCGACCAAAATTAGAGCTTCCTTGTCACAAAGCGATCCTTAGTGCTAGATCTCCATTCtttagaaatttaattcaaCGTCGATCTCGTACTGGTGAAGAACATACCGAACGGGCTCTTCACATTCCCACGCGAATAGTTTTAGACGAATGTGTCATTCCAAAACGGTATGCTCGCGTTTTATTACATGCCGTATACTTGGACACGGTAGATTTATCATTAATCCTTCGTGGGAGCGGTTGCGGGGCCGGCTCGGGTAGCCTAGGTGAAGTTCAGGCACTCACGCACACGGGACGTGCACGACCATCACCTCTAGAAGAGGCTATGGAGTTGTATCAGATTGGACGATTTTTGGAATTGGATATATTGGTGCAAGGCTGTGAGGATATTATTATCGAATGGTTGTCGTTAAACTCACTTCCAACAGTTTTACGGTGGTCTTCACAGCCGCACGGTTCCGCTTGGGTTCATCGTCAAGCGCTCCATTATCTTCGAGAAGAATTCCATATGGTGTCACAGTCGCCAGTGTTGTACCAATTGGATAAAGAACACCTTATAAGCGTTTTGAAAAGCAACTTTCTACAGGCTAGTGAATTAGAAATTCTCCAAGCGATTCTTAAATGGGGTGAACACGAGTTGACACGTCGAATGGAAGACAGGGAACCAAACTTACTCAGTCACACCGCTCACTCAGTAACTCGAAAAGGTGTAAAGAAACGTGATTTAAGTGACGTAGAACTTCGTGAAATTCTTTCCGATTTAATTCCATTAGTTCGTGTGGATCATGTGCTTCCACAAAATAGTGAAATATTACAGCAAGCGATCAAGCGTGGCCTGGTTAGTACGCCACCGTCTCACATTATGGGCGACGACCGCGAGAATCATCGAGTGAACGCATGGATTCGATGTAGAAACAACAATGGTCTGTTCGTGCGACCACGATTTTTTATGCCTTACTATGAGGAGTTAAAGCTTCTCGTCGAGGACCAGTTAGTACAAGAAGTGCAGAGACTTCGTATGCACAGATACATGCCAGACATACCCGATACGCTTTACATGGTTGAAGATAAACCACGCTCTGCTAACACGGCTGGACTCGACGTGCTAGCTGCCGCTTTACCCGTGCCTGATGGAATGACATTATGTGCAATGCTTAAACGAGTCAGTAAATTGAAACAGACACCGATATGTCAACGAGCCATTGCCTCGCCGCTCTCTTCTCGGGCCGAGATCAATCGTCAGATCAAGCTACGAGTTGTTCGCGAATTTAATTTACCTGACGCTGTTGCAGATGTGCTTGATAACACAGCAGTGTTTCGACATGAGGAACATGAGGAGCGTGAACAGAATCATGTTGATCACGAGCCTCCGATACCGTCAGTATGTCCCTCACCGGAACGCACCACCCGCACCCAACAATCCCAAGGACCACAAACACACAGCTCAATGTGCTACGGGCGAAATTTGACTTTCCCGCGGTTTGGCAGTGGTATGGCACAAAGAAACGAGCTTCCCGCGATCGTCACCGAGGGTGATGCGTTCAGACACTTAGGCGGTGAGCCAGAATCGAGTTCGTGTAGTGATGGCCACCTGTCCGACATAATGCCCGACGTAGCAATGGCCACCGCCAGTTTTGGGCAACTACAATTACAGGAACAACAAGAGTTGGAGTTGGATCTTGGCGACGGTGCTAGTCATATGCACAATCAACTGATGCAACAGGGCGCGGCATCCTCGAATAATCCGTTTCTTGTCGAACCAAATCGTGGTTCGCACGCCTCAATCCCCTGTTATCGATATCTCGGCAACATGATCGGACCGCCAATTAATTATTACAGTGCAAATCGTGTCAACGATCGAAACAATGATAATTCCAATTCCGCCATGGATTCAGGATATCACACCGGACCTCCACGATACTTGTAA
Protein Sequence
MNLFGCLLPCSLKRGWWNFEETESNNGVRTDLLAAPTAMGANASNTAGVSGVSDMPLPQSLAGAAASTGASLSQDGVIVRERKKKVTGFATLRKKFIRRRRSSKPCDHGRMLRELVADWSPLELAALLEEYEALAALKDLSFQAELARPPATTFKQDLSALYDFKYCTDADLVFRGACFPIHRALLSARCPYFRDLLAGCPGYGARICLELNRTASLDVQLFSALLRYLYTGDICPHESNIDLELLRRLGEEFGTPNPLEHDLRYLLETGDYADAALVFTSDGNDYQRPDSGSSEYGFRPKLELPCHKAILSARSPFFRNLIQRRSRTGEEHTERALHIPTRIVLDECVIPKRYARVLLHAVYLDTVDLSLILRGSGCGAGSGSLGEVQALTHTGRARPSPLEEAMELYQIGRFLELDILVQGCEDIIIEWLSLNSLPTVLRWSSQPHGSAWVHRQALHYLREEFHMVSQSPVLYQLDKEHLISVLKSNFLQASELEILQAILKWGEHELTRRMEDREPNLLSHTAHSVTRKGVKKRDLSDVELREILSDLIPLVRVDHVLPQNSEILQQAIKRGLVSTPPSHIMGDDRENHRVNAWIRCRNNNGLFVRPRFFMPYYEELKLLVEDQLVQEVQRLRMHRYMPDIPDTLYMVEDKPRSANTAGLDVLAAALPVPDGMTLCAMLKRVSKLKQTPICQRAIASPLSSRAEINRQIKLRVVREFNLPDAVADVLDNTAVFRHEEHEEREQNHVDHEPPIPSVCPSPERTTRTQQSQGPQTHSSMCYGRNLTFPRFGSGMAQRNELPAIVTEGDAFRHLGGEPESSSCSDGHLSDIMPDVAMATASFGQLQLQEQQELELDLGDGASHMHNQLMQQGAASSNNPFLVEPNRGSHASIPCYRYLGNMIGPPINYYSANRVNDRNNDNSNSAMDSGYHTGPPRYL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01349007; iTF_01349797; iTF_01060857; iTF_00332581;
90% Identity
iTF_00332581;
80% Identity
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