Bneb002162.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Brachynemurus nebulosus
Gene Symbol
-
Assembly
GCA_035578155.1
Location
JAPWDM010000001.1:64117177-64121944[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 9.8e-13 7.9e-09 36.4 0.2 8 70 208 268 203 272 0.86
2 2 2.8 2.3e+04 -3.5 0.1 10 16 365 371 362 372 0.85

Sequence Information

Coding Sequence
ATGGAGACGTCAGAAGCATTAAACGaagATATCGAAAACGACAATAACATAAATGGAGATGATTCTAATCTTGAACCGGTGGATGCAAATAAACCTATAATTGATGTACAGTTATCAAAGGCAAGATCTGAATTAAATTGTGATGATGTATTGGATACAAATAAACAACCCATTTTAAAACGAAAAGCAGAAGATGGTGCAGTAGAACAAACTgagaaaatgatgaaaattgaaaatccaGATATTATTGATCATTCTTCAGAAAATGAAGcaggTACTAAAAACCAAAATGAAGATTCTGATGGCCAATCAAGCGGTGATGAGCCAAAACTTACAATAAAAATAGAAGATGATAATACGAGTGATAAATTAAAGAGTGAAGATGACGAAGAAAATAAAACATCACAAAAATCGGAAAATACTCCTCAAGCTACTGCAAGTGGCACTAAAGCGGACGAAAAAATTGATAACGAatcttcaaaaacaaaattatctaaAAGTCCACAAACTCCTACAACAGAAGCTATACGTCAAAGTCTTCGTGCTAACAGAAACAGTAACCCAGCTGcgtttttagtaaaaaaaccAAAGCTTCCAACAGATATGTCGAATCCAGCTtataaaaaaccatttttgtATGGATGGAAACGTGAACTTGTATACAGAGCAAATTCAGAAAGTGGTCCAAAACGAAATggtgatatttattattttacccCTGATGGCAAAAAAGTTCGATCCATGAGAGAggtattagaaaatttaaaaacaaaagaactgtctacagaaaattttactttttacaaAGAACCATTAGGTATGAATGATCCAGAACTAGAAATTATTAGAGTGGCTAAAGTTAAAGGTTCAGCACCTGTAGCTGGTTTTTCgacacataaaaaatttttgaaagcaaAAAAAGAACAGAAAACTTTAGAAAAGTCTATTTTATCAAGTGGTAAAACAAAATCACCGAAATTTGGAAGTGCTTTAAAAGTAAAACTTTCTGGGGCTAGATTAAGTCAAAGTAAAAAATCAAGTAGTAAGGTTGAAAAAAGGAATAAGTCGTCCAAAGTATCATTGCAAATGGGAACATTACCACCTGGATGGCAGTCCccacaaaaaaaagttgaaaaattACTGGGCAGCGTACCGGAGAAGGTGATGAAATTGAACGAACAATGCTCGGTTAATTGTGAGGGTGTTGCGCCTGCGATACCAAATTTACAATGCAGTCTTTGTCTTTGTTTATATCATCCAGAATGTGTGGGATTGACACTTCCAAATGCTGATTGTCAAGAAAATTATGTGTGCAAGAATTGCCAACCAGAAGATGCACCGACATACAAGGACGGAGAACGAGTAGAAGCTGATTCTTCCTTACCACCACTAACTCCTTTTAGTGCTATAAAAACGCACGCTCCTGTATCAACAATTCCTCCTAGACTTCATAGAATTAATCATAATGCTGATAATACACgagaaacgtttaaaaaaaattcacgacaTTCTAAATTGTTAACTTCTCATCAAATaagaacaaatgaaacaaatcGTTCAGGGAGTGCACAGTCGGAAACAACTAAAAGTTTAGTTGGTTCTGTGACGACGTGGCTTCATTCTAGCTCAACCGTTCAAATGGTTCAGTCAAACAATGACTCAGTGGCGTCTCTCACAAACACTGAGTCGTCACAATTTCAGGCAACTATTGGCGGTCGTAAATTTATAATCATTCCGAAACAAAATGTTCTATCAATCCATCCAAATGAACAGACCAGTATAGTTCCTCCTTCAGAAAATGCACAAATTCCTTCCACACCTTGTAATTCCGATACCACACCGGTTCCATCGTCTACAGATAAAGTACCGGATACTGCCTCGTTGGGTCCACTTTCTTATAATTCTGAAGCCCTTACAATTACAACAAATAATGCTCATTCACAGGCATCGCAGCCTGTTGAAACCTCTTTATCCTATTCACCCACCGCAGCGGATCATCATATGAGAACACAGTGGCAAGGAGATGGCTTATTAAAACAAACGTCAGCACAACTAAAACCTGATAGAATAAGTTcaagaaataaaagaaatagtCAAAGAAACTCCACAGCTTCAGGAAATTTCGTAATAGAAAAAGTGGAAAAACCAAATTTAGACacaagagaaaaagaaaaatttatgcagaattttttgaataatgttTCAGTTGGTTATTCTGTACTTCTTCAAGTATTTCAGTATTTGAAAGTACAAGAATTATTACGAGCAAGTCGAGTTTGTCGAATGTGGAAAGATTTAGCAAATCATCCATCTCTATGGCGTACCGTTCGAATGAAGAACTCGCAGGTACGTGATTGGAGGGGATTAGTAAAATCGTTAAAACGACATGGAACGGAAACGTTAGATTTAAGAAAAGTGTTATTACCAGGTAGTGGAGATGACATGTGGTCTGCCTTCACTGCTGAATTAGGTAATGCTGATACGTTAAAAAGAATCGATTTATGTCGTTGTCCAGCCACCGTTGTAGAAGAATTGGCAAACTCAAATCAAAACCTGGAAATAATTAATGCTATTTCAATTCGTTGTACAACAATCGATTTGTCTTCctacgaaaaattaaaaaatcttcgTGAATTGAGATTAAAATCACAGAATGGAGTAGAACTTACAAACACTTTTTCATTTCTGGAACATCTTACTTTACTGAAACATTTATCATTATTATCTTTTAAAGATTTAGGAAAGAAGGGTATAGAATCTGTTGgtaaattaactgatttagaatcTCTGGAGCTTGGTGAATGCGATtctttagctgaaaattttggttctgaagtaatttcaaaattggAAAGAGTTGAAAAAATGAGATTAGAAAAAGGTCCATCAGGTCCGAGTACTTACAATATATTAGAAGCAATAAGTAAGCTACCCAAAATATATCAAGTTGAGTTAGTCAATTTTGATGTGAAATCTGGTTTTGATGAAGCATTATCTCTTTGCACAAATATTAAACGGCTATTATTAATACCAACTTATATTTCTCAGTCGGCTACAACGAATAATATggttttaaatggaattttccAACTTTCTGAGAATTTAACGTATTTTATATGGGGTATAACCTTAGAACTGCTTCGTGTTACGGAACTTTTTATCGATCAATGTGATCAAACcccgaagaaaaaaaattcgccCAAGAAAGATAAGAAAGGGACGGGTGAcagtatacctatattaaaaccAGTGCCGTTTGTGGAAGATTTCAAAGGTGGAGGTGACGTTACCCAAGATAATACCCAAGTTGAAATATTGCCATTGAATGCGTTACAAAAACTGTTAACAAATAAACTACAAAAtacaaaagttaaaatattaaaaataccgtATCATGCTACTTGGCGGCAAAGTATAAATGATACAATCCAGTGA
Protein Sequence
METSEALNEDIENDNNINGDDSNLEPVDANKPIIDVQLSKARSELNCDDVLDTNKQPILKRKAEDGAVEQTEKMMKIENPDIIDHSSENEAGTKNQNEDSDGQSSGDEPKLTIKIEDDNTSDKLKSEDDEENKTSQKSENTPQATASGTKADEKIDNESSKTKLSKSPQTPTTEAIRQSLRANRNSNPAAFLVKKPKLPTDMSNPAYKKPFLYGWKRELVYRANSESGPKRNGDIYYFTPDGKKVRSMREVLENLKTKELSTENFTFYKEPLGMNDPELEIIRVAKVKGSAPVAGFSTHKKFLKAKKEQKTLEKSILSSGKTKSPKFGSALKVKLSGARLSQSKKSSSKVEKRNKSSKVSLQMGTLPPGWQSPQKKVEKLLGSVPEKVMKLNEQCSVNCEGVAPAIPNLQCSLCLCLYHPECVGLTLPNADCQENYVCKNCQPEDAPTYKDGERVEADSSLPPLTPFSAIKTHAPVSTIPPRLHRINHNADNTRETFKKNSRHSKLLTSHQIRTNETNRSGSAQSETTKSLVGSVTTWLHSSSTVQMVQSNNDSVASLTNTESSQFQATIGGRKFIIIPKQNVLSIHPNEQTSIVPPSENAQIPSTPCNSDTTPVPSSTDKVPDTASLGPLSYNSEALTITTNNAHSQASQPVETSLSYSPTAADHHMRTQWQGDGLLKQTSAQLKPDRISSRNKRNSQRNSTASGNFVIEKVEKPNLDTREKEKFMQNFLNNVSVGYSVLLQVFQYLKVQELLRASRVCRMWKDLANHPSLWRTVRMKNSQVRDWRGLVKSLKRHGTETLDLRKVLLPGSGDDMWSAFTAELGNADTLKRIDLCRCPATVVEELANSNQNLEIINAISIRCTTIDLSSYEKLKNLRELRLKSQNGVELTNTFSFLEHLTLLKHLSLLSFKDLGKKGIESVGKLTDLESLELGECDSLAENFGSEVISKLERVEKMRLEKGPSGPSTYNILEAISKLPKIYQVELVNFDVKSGFDEALSLCTNIKRLLLIPTYISQSATTNNMVLNGIFQLSENLTYFIWGITLELLRVTELFIDQCDQTPKKKNSPKKDKKGTGDSIPILKPVPFVEDFKGGGDVTQDNTQVEILPLNALQKLLTNKLQNTKVKILKIPYHATWRQSINDTIQ

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-