Basic Information

Insect: Bombyx mori
Gene Symbol: prg
Assembly: GCA_027497135.1
Location: CP114953.1:6451863-6453680[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.26 14 6.4 1.6 2 23 178 200 177 200 0.85

2 10 0.051 2.9 8.6 2.2 1 23 206 229 206 229 0.96

3 10 6.7e-06 0.00037 20.8 4.1 1 23 235 257 235 257 0.96

4 10 1.3e-06 7.2e-05 23.0 3.0 1 23 263 285 263 285 0.99

5 10 1.7e-05 0.00094 19.5 0.1 1 23 291 313 291 313 0.97

6 10 0.0011 0.059 13.9 1.4 1 23 319 341 319 341 0.97

7 10 0.00026 0.014 15.8 3.4 2 23 436 458 435 458 0.95

8 10 0.00028 0.016 15.7 1.5 1 19 464 482 464 486 0.94

9 10 0.0018 0.1 13.2 2.7 3 21 494 512 492 513 0.92

10 10 0.0013 0.073 13.6 0.0 3 23 523 543 521 543 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.26	14	6.4	1.6	2	23	178	200	177	200	0.85
2	10	0.051	2.9	8.6	2.2	1	23	206	229	206	229	0.96
3	10	6.7e-06	0.00037	20.8	4.1	1	23	235	257	235	257	0.96
4	10	1.3e-06	7.2e-05	23.0	3.0	1	23	263	285	263	285	0.99
5	10	1.7e-05	0.00094	19.5	0.1	1	23	291	313	291	313	0.97
6	10	0.0011	0.059	13.9	1.4	1	23	319	341	319	341	0.97
7	10	0.00026	0.014	15.8	3.4	2	23	436	458	435	458	0.95
8	10	0.00028	0.016	15.7	1.5	1	19	464	482	464	486	0.94
9	10	0.0018	0.1	13.2	2.7	3	21	494	512	492	513	0.92
10	10	0.0013	0.073	13.6	0.0	3	23	523	543	521	543	0.92

Sequence Information

Coding Sequence: ATGGAAGATTCCTTTATTATAGCCAATTTTAATTCTCTGTGTCGCCTTTGCCTCGGTAAAAGTAGACTCGCCATCTCAATATTCGGAGCTGCACCTGATGACATTAATAACGTATCATTGACCTCCAAAATAGCTGAATGTTTTGAGTTACAGATCGATCCTAATGATGGTTTACCTGGCAGGATTTGTTACAAGTGCTTATTCAAAGTGGACAAGTGTTCAAAATTCAAATTACAATGTATCCAAAGTGAAAACAGACTCAGACAAATCACAAATCGTATAAATGAAGTAGATACTTCAAACTCATCTGAAATTACTAATTACACATACAGCAATTCCCAAGATGAACAGAAACATAAGCCTGAAGATTTTATTGTTGAAGATAGCGTTGTGATGGTGGTTGATCCTAGTCTTGATTATGATTCTTCGGATGATTCTGAAAATGTAGAAACTGTGGAGCAAGAAAATACTGATCGAGGCAATACTCCTGATGCGGATGCAATTCCGGAAACATTTTTCAAGAATGTTTCAATGTGCCAATATTGTGATCAAGCTTTCATTTCACAAGAAAAATGTAAAGAGCATGAACTAAACTATCATGATCCAGACATGCCTTTTAAATGTTATGAATGCAGTTTGGCTTTTGTGGAAAGAAATCAGTATGTACAGCATACGAAACATGTCCATGGAAATGACAAGCCCTATCATTGCCCTGAATGTAATAAATGTTTTGGACGAAGATCTGATCTAAGAAAACATTCTATTGTACATACAGGTATCAGACCTTACCAGTGTCAATTTTGCTTGAAGAGTTTTTCACGTAACACAAACTTGAGCAAACACTTGAGAATACACGCTGGTCACAGACCTCATGTTTGCCCTCTGTGCCCTCGTAGCTTTGTAGCCAAAGGTGACCTACAACGACATGTTCTTGTTCATTCTGGCATGAAGCCTTATTCGTGCAGAAAATGTCCCTCTACATTTGGACGAAGAGATAAGCTCATTAAACATGAACTAAAACATGGAATTGTTGCCACTGAGGATAAACCTGAAGACTATGCCAACAGTGTTAAACAGGATCCAAATGACATTGTTGTCAGTGTCAATCCTTTCAGTAACCTCATGACTTCTCCAACACAAAATTCAGATCCTTCAAACCCTACTTACGAACTTCCTAGTGTTCCTGACCATATTTCTGGGGAAAGTAGTTTTATAAAGATGCAAAAAGATCCCTCCACATCACATAAACAACAAAACTCATCACCAAAAAAGGCTACACCAGTTAAGAACAGACCAAAAAACATAAAATGCCATCACTGCACAAAAAAGTTTTCTTCCCTAGATGCATACAAAACTCATGTTTCAATTGCTCATATGGGATCAAGAGGATTTCAATGTAAAATATGTTTTAAGAAATTTTCCAAAAAAAGGGAGTTAGATCGACATGCTCCAATTCACACTGGAGGTAAACAATTAGCTTGTGACCACTGTGATAAAAAGTTTACTAAAAAAGACAAATTTGATAAACACAAACAGTCACAGGAATGTTTGGTTGTGAATATGCCTTGTATAGAGTGTGGTGTTACCTTTGAAAAGAAAGCTGACTTGGTTGCACATATTAAATCACACTTCAATGATACCTATGATAAGTTACAGATTCCAGATGTTGAGATTAAAGTAGAGAAAGATCCAGAAATACCATGTGATGAAAACTATTATGATTTGGGAACATGA
Protein Sequence: MEDSFIIANFNSLCRLCLGKSRLAISIFGAAPDDINNVSLTSKIAECFELQIDPNDGLPGRICYKCLFKVDKCSKFKLQCIQSENRLRQITNRINEVDTSNSSEITNYTYSNSQDEQKHKPEDFIVEDSVVMVVDPSLDYDSSDDSENVETVEQENTDRGNTPDADAIPETFFKNVSMCQYCDQAFISQEKCKEHELNYHDPDMPFKCYECSLAFVERNQYVQHTKHVHGNDKPYHCPECNKCFGRRSDLRKHSIVHTGIRPYQCQFCLKSFSRNTNLSKHLRIHAGHRPHVCPLCPRSFVAKGDLQRHVLVHSGMKPYSCRKCPSTFGRRDKLIKHELKHGIVATEDKPEDYANSVKQDPNDIVVSVNPFSNLMTSPTQNSDPSNPTYELPSVPDHISGESSFIKMQKDPSTSHKQQNSSPKKATPVKNRPKNIKCHHCTKKFSSLDAYKTHVSIAHMGSRGFQCKICFKKFSKKRELDRHAPIHTGGKQLACDHCDKKFTKKDKFDKHKQSQECLVVNMPCIECGVTFEKKADLVAHIKSHFNDTYDKLQIPDVEIKVEKDPEIPCDENYYDLGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01490377;
90% Identity: iTF_00236091;
80% Identity: iTF_00236091;