Bmaj001116.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombylius major
Gene Symbol
ham
Assembly
GCA_932526615.1
Location
CAKOBF010000026.1:687729-713739[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.2 12 6.8 0.8 1 22 303 324 303 326 0.89
2 9 0.00066 0.039 14.6 0.5 1 23 333 356 333 356 0.94
3 9 1.2e-07 6.8e-06 26.4 1.6 1 23 362 385 362 385 0.98
4 9 1.8e-06 0.00011 22.7 1.7 1 23 391 413 391 413 0.95
5 9 4.5e-05 0.0027 18.3 5.0 1 23 419 441 419 441 0.99
6 9 0.0014 0.083 13.6 3.5 2 21 449 468 448 473 0.94
7 9 7.1e-09 4.2e-07 30.2 1.3 1 23 822 844 822 844 0.99
8 9 5.6e-07 3.3e-05 24.3 1.7 1 23 850 873 850 873 0.97
9 9 4.9e-05 0.0029 18.2 6.8 1 23 879 901 879 901 0.99

Sequence Information

Coding Sequence
ATGTCAGGAAGCAGTGGTGACGAGTACGAATATGGTATACCGTCCAGTCTTCAAGTAATACCACTtgatttagataaaaatagcaataatagcaatagaagcaataataataataataataaaaataataatttacatgatatacaaaattattattatcataatcaacaacaacaacaacaatatcatcatcatcatcattcacatatgatcacatcagtaccttcattatttaatgcaacaacaacaagaacaataccaacagaatcagaatcatcaatacaaacaacaccattagattatcaatgtaATAATAAATTACAAAATCGTAATACATCAATGAGAAATTTTCAAACAAACGAAATGTCATCAAGATTACAAAATGATAATATAAAATTTGATTTAAATATTAAAGATAATGGTGTTTATACAAATGTTTTATTACATCGTGGTACACGTTTGGGTCCATTCTCAATGAAATGGAGTAATAAACCGACAGATAGAAATTATGCATGGGAGGTTGTTGCTGGATCAAATGTTCGAGGCTGGTTGGAACCAGTTGTTGAATCTGAAAGTTGGTTAAGAAAATTACGTTTTCTGGTGGAAGGCAATAATATTGAAATTGCAAATTTACAACATTTTTTAGCGGCAGGTTATTTGTGGTTCGAAGTACAAAAGGATATTCCGGCAGGAACTGAAATAATAGCGGGACCAAAGACACCTCTACAATTAGGAGATATTTTCAATAATGGAACATTTGAAAATAAAAATCCTAAAAGAAGTGAATCACAGAATTCGATTTTAAATAGAAATGAAGATGATGAATTAATTTCAAATAATTTAGACAATAATAAATCAATAAATAATCAACAAGATCAGGATTCTGATGATGAAGAAGGTATAAATTTTAGATGTAATCTTTGTGAAAGACAGTGTCGTGATATTGATAGCTTGGATTATCATTTAGTTGCTGAACATCATTTTCCAAAAGACAATTTTAGGTGTGAATTGTGTCCAAAAAGTTATTATTATCGTCCTTCATTATTAAGACATCGTGCTCTTGTACATGGTGAATTAAGAAAATATCCTTGTGAAAATTGTACAAAAGCATTTTGTGATCCATCAAATTTACAACGACATATTCGTTCACGTCATAGTGGTGCAAGAAGTCACGCTTGTCCAGAGTGTGGTAAAACTTTTGCAACATCATCTGGACTTAAACAACATACACATATACATTCCTCAGTTAAACCATTTCAATGTGAAGTTTGTTTTAAAGCATACACACAATTTTCAAATTTATGTCGACATAAACGTATGCATGCTGATTGTCGAATGCAAATTAAATGTACGAAGTGTGGTCAAAGTTTTAGTACTGTGACATCATTATCAAAACATAAACGTTTCTGTGATTCTCATCATTCTCATCATCAACAACAACAAGTTCATCCACCACCTCCACCACAATCAAATCCAATCGGAGTTGTACCACCATCTCCAATGACGACCCCACCAAATCCTTTTTTCATATTTCGTGGACCAACACCATTTTTTCCATCAAGTTTTTCTCCATATGGATTTCAAGGAATATTTCCACCAAGTCCTACACAGACACCAGCTTTTCCTCTTTTTTCATTTTCTAAACCAAACTTAGATGTGCCTCTTATGGATAAAGAAAGGATATCACCACAAAGAAATACAAGTAGCAGTTTAGGTGGAGAATCATATATTAGTCCAATAATTTCTGATGAGCGTAGATTAAATCATATGATACCATCACCAACAAGATCAATAGCAATGTCTTCACAAGAGAGTAATTGTAATATTGATATGAAAATTAGTCAACTTTCTCCCCGTAGTAGACACTCAAGAAGTCCGGAAGGTAATTCTTCAAATTTAATGTATTCCGAAAGAGATGAATCTTTTAGGGATGATTCCAAAGAAATAAAACAAGAAAGACAAACACCTTTGGAAGATAAGGGATCAATAAATGTGACGAGGACACCATCACCGAACAACGAAGAAACACGAACTTCTCCATCAGTACATACCGAACAGCCGCTTGATCTTTCAGTGACACGGAGTCGTAATAGAAGTCGTAGTTTGACACCAGAGCCTTGTAATAAAAAACGTGATATACCATCACATCAATCATTTCAGGCAAGTCGAACACCATCAGTATCACCGGGATTAACACCTTCACCATCACCTCCTGGACCACCAATGGCATGTCCTAGACCAATCCATCCTATATTATTAGAAGCTATTTATCGACCAACTACCGGATTAAGTGCAGCCTTTCAACGTCCCTTTCCTTTTTTAGGGCCAATGGGCGGTCGCGGACCAGGATTTGACCACATACTACATCGGAATGGGCCGTTTCCGCCCAAACCATTTCATGAAACCCTAATGGTAACTGGAGGTCTAACAGGACCATTAACCACAACTAAAATtaaagatcgttatacatgtaaattttgtggtaaagtatttccacgttcagcaaatttaacacgacatctacgaacacatactggtgaacaaccatataaatgtaaatattgtgaacgatcatttagtatatcaagtaatcttcagcgacatgttagaaatattcataataaagaaagaccatttaaatgtcatttatgtgatcgatgttttggtcaacaaacaaatttagatcgtcatttaaaaaaacatgatactgatgcaaaTGGTTTAAGTTTAAGTGTTGGTGATTCACCATCATCAAATGAAGCTGATAGAGAAGATACATATTTTGATGAAATACGTTCATTTATGGGTAAAGTTACTTATAATAATGGTATTTATACACCAATTAGTATAAGTACTGGTGAAAATGAAACTGAAGATGGTAGTAGTGATATTGACAACGAAATAATTAATGAAAAAGATAATATAACGAATAACAACGAACATGATGCTGCTATTGAAGTTTCAACATAG
Protein Sequence
MSGSSGDEYEYGIPSSLQVIPLDLDKNSNNSNRSNNNNNNKNNNLHDIQNYYYHNQQQQQQYHHHHHSHMITSVPSLFNATTTRTIPTESESSIQTTPLDYQCNNKLQNRNTSMRNFQTNEMSSRLQNDNIKFDLNIKDNGVYTNVLLHRGTRLGPFSMKWSNKPTDRNYAWEVVAGSNVRGWLEPVVESESWLRKLRFLVEGNNIEIANLQHFLAAGYLWFEVQKDIPAGTEIIAGPKTPLQLGDIFNNGTFENKNPKRSESQNSILNRNEDDELISNNLDNNKSINNQQDQDSDDEEGINFRCNLCERQCRDIDSLDYHLVAEHHFPKDNFRCELCPKSYYYRPSLLRHRALVHGELRKYPCENCTKAFCDPSNLQRHIRSRHSGARSHACPECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCTKCGQSFSTVTSLSKHKRFCDSHHSHHQQQQVHPPPPPQSNPIGVVPPSPMTTPPNPFFIFRGPTPFFPSSFSPYGFQGIFPPSPTQTPAFPLFSFSKPNLDVPLMDKERISPQRNTSSSLGGESYISPIISDERRLNHMIPSPTRSIAMSSQESNCNIDMKISQLSPRSRHSRSPEGNSSNLMYSERDESFRDDSKEIKQERQTPLEDKGSINVTRTPSPNNEETRTSPSVHTEQPLDLSVTRSRNRSRSLTPEPCNKKRDIPSHQSFQASRTPSVSPGLTPSPSPPGPPMACPRPIHPILLEAIYRPTTGLSAAFQRPFPFLGPMGGRGPGFDHILHRNGPFPPKPFHETLMVTGGLTGPLTTTKIKDRYTCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFKCHLCDRCFGQQTNLDRHLKKHDTDANGLSLSVGDSPSSNEADREDTYFDEIRSFMGKVTYNNGIYTPISISTGENETEDGSSDIDNEIINEKDNITNNNEHDAAIEVST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00234234;
90% Identity
iTF_00234234;
80% Identity
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