Bmaj015498.1
Basic Information
- Insect
- Bombylius major
- Gene Symbol
- ZEB2
- Assembly
- GCA_932526615.1
- Location
- CAKOBF010000449.1:91054-93098[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 11 0.42 25 5.8 0.4 1 23 49 72 49 72 0.93 2 11 3.7e-06 0.00022 21.7 0.4 2 21 337 356 337 357 0.94 3 11 0.00068 0.04 14.6 0.1 1 19 375 393 375 395 0.95 4 11 0.007 0.41 11.4 0.6 2 23 432 453 431 453 0.96 5 11 0.028 1.7 9.5 7.3 1 23 459 482 459 482 0.97 6 11 1e-05 0.00061 20.3 0.5 2 23 489 510 488 510 0.97 7 11 0.0031 0.18 12.5 0.4 2 23 516 537 515 537 0.96 8 11 3.1e-05 0.0019 18.8 2.2 1 23 543 566 543 566 0.97 9 11 1.4e-05 0.00085 19.8 1.9 1 23 572 594 572 594 0.96 10 11 0.001 0.059 14.0 1.4 1 23 601 623 601 623 0.98 11 11 4.5e-05 0.0026 18.3 1.5 1 23 629 651 629 651 0.97
Sequence Information
- Coding Sequence
- ATGTCTCTAGAGGAGCCAGAAAAAGTACTTGGATTTTTTGAAAATGAAAGTCTTGAATTTAATGTTGAAGTAGGAAAAATGGAGATTAAAGTGGAAAGGAAATGTGGAGAAATTTTCATTGATGAAAACAATTATTTATTCAGTTTCTTATGTACACTTTGTAAAGCTCCATTTGAAGAAGTTTCAAAATTTTTTTTACATATTAAAGAAAATCACACGTATGAAGATGAATACATGATGGATATGGAAGTGAAGGAGGAAGGTGAATACAAAGGGGATAAAGGTGATGAATACAAAGGGGATAAAGATGATGAATACGAGGAGGATAAAGGTGATGAATACAAAGGGGATAAAGATGATGAATATGAGGAGTATAAAGGTGATGAATACGAGGACGATAAAGAAAATGAATACGAGGAAGATAAAGTAGATGAATACGAAGAGAATAAAGATGAAGAATATGAGGAGGATAAAGATGAAGAGTACGTGCAGGATAAAGATGAAGAGTACGTGCAGGATAAAGAAGATAAAGAAAATGAATACGAGGAATATAAAGTAGATGAATACAAAAGAGATAGGGAGGATGAACACGATAAACAAGATGAGCACACACTAGAAGAATTAATGCCATGGTCACGAAATAAAGATGATTCTGAAATTGTAAAGTCAATTATAGAAAGAATTGCAATCGATAATACCAACGTGATTCCCGTTATATTTAAATTTACAGAAGATAATTCAAGTGATGAATCAATATTTATTAATATAAATGAAGGTAAAAAGAATCCTCGAAAAAAATTAAAAAAAGAAAATGAACAAGTAAACACAAACTCCACATTAACAGTACTTTCGTTTGATGAAGAAACAAATAATATGAAACATAAAAGTGAAGAAAATGAACAAAATGAGCATGATAATATGAAAGATGAAAATGAAGAATATGAACAAATTTGGAACGATAATCTGGAAAATAAAAATGAAGAAAATGAACAAAATAAACAGGGACCAAAATGTACAATATGTGGAAAAGTATTTTCACGTTTAGCTTCTTTAAATCGACATAAAAAACTTGTAAAATGTAATGAAAAACCATTAAAAATTAAAGTAGATAAAATAAAAGTATACATTTGTGATATTTGTGGTGTAAGATTTAAATCAAATCGTGCTCTTGAAGAACATAAATATTTTACAAAACGTGGGCATAATTTAGGTTCAAATCCTCAATATCAATCTGATAAAGCAGTAAAGAAAAAATTAGTAAATTTATCAAAAgcatcacaaaatgaaaaattaaaatgtaaatattgtgatagaatttttgtagatacaacaaaacgtgctgatcatgaacgtattcatactggtgaaaaaccatttgaatgtaaaatatgtggtagacgttttcataaaaaatcatattgtcaaatgcatgaacgtacaacacatgcaacagaaagattatcaacatgtgaaaaatgtggtaaaacatttaaaaatgaaatagctgttatggcacatatgaaaagacatggtaaaccaaatttaccatgtaattattgtgaaaaattatttataaataaagttgaacgtagacaacatgaaagaatacatactggagaaagaccatatatatgtaaattatgtgataaatcatttcaaacaagtggaagtttaagtgaacatcatagaataaaacatttaaatgttagattatattcatgccaatattgtgatagaagtttttatactaaacaacaattaacaaatcatagtgctgtacataaacgtgatgtaaaaccatttaaatgtgaattatgtaatacatcatttgcattacgaagaagtttatcactacataaaaaaattcattcaaatgaacgtaattatatatgcagaatttgtggtcgaagttttaaGCAATATTCTGGATTATATCTTCATAAAAAAAATCATGCTAAAAATACACAAAAAAGATGA
- Protein Sequence
- MSLEEPEKVLGFFENESLEFNVEVGKMEIKVERKCGEIFIDENNYLFSFLCTLCKAPFEEVSKFFLHIKENHTYEDEYMMDMEVKEEGEYKGDKGDEYKGDKDDEYEEDKGDEYKGDKDDEYEEYKGDEYEDDKENEYEEDKVDEYEENKDEEYEEDKDEEYVQDKDEEYVQDKEDKENEYEEYKVDEYKRDREDEHDKQDEHTLEELMPWSRNKDDSEIVKSIIERIAIDNTNVIPVIFKFTEDNSSDESIFININEGKKNPRKKLKKENEQVNTNSTLTVLSFDEETNNMKHKSEENEQNEHDNMKDENEEYEQIWNDNLENKNEENEQNKQGPKCTICGKVFSRLASLNRHKKLVKCNEKPLKIKVDKIKVYICDICGVRFKSNRALEEHKYFTKRGHNLGSNPQYQSDKAVKKKLVNLSKASQNEKLKCKYCDRIFVDTTKRADHERIHTGEKPFECKICGRRFHKKSYCQMHERTTHATERLSTCEKCGKTFKNEIAVMAHMKRHGKPNLPCNYCEKLFINKVERRQHERIHTGERPYICKLCDKSFQTSGSLSEHHRIKHLNVRLYSCQYCDRSFYTKQQLTNHSAVHKRDVKPFKCELCNTSFALRRSLSLHKKIHSNERNYICRICGRSFKQYSGLYLHKKNHAKNTQKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00234216;
- 90% Identity
- -
- 80% Identity
- -