Bdis001118.1
Basic Information
- Insect
- Bombylius discolor
- Gene Symbol
- ZEB2
- Assembly
- GCA_939192785.1
- Location
- CALNDV010000056.1:485724-487652[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 12 8.8 5.1e+02 1.4 0.0 5 17 34 46 33 47 0.89 2 12 0.063 3.7 8.2 0.3 1 23 48 71 48 71 0.93 3 12 8.2e-06 0.00047 20.4 0.3 2 21 298 317 298 318 0.94 4 12 0.00038 0.022 15.2 0.1 1 19 336 354 336 356 0.95 5 12 0.0056 0.32 11.5 0.6 2 23 393 414 392 414 0.96 6 12 0.023 1.3 9.6 7.3 1 23 420 443 420 443 0.97 7 12 8.3e-06 0.00048 20.4 0.5 2 23 450 471 449 471 0.97 8 12 0.011 0.65 10.5 1.3 2 23 477 498 476 498 0.97 9 12 2.5e-05 0.0015 18.9 2.2 1 23 504 527 504 527 0.97 10 12 1.2e-05 0.00067 19.9 1.9 1 23 533 555 533 555 0.96 11 12 0.00073 0.042 14.3 1.1 1 23 562 584 562 584 0.98 12 12 6.7e-05 0.0039 17.5 1.0 1 23 590 612 590 612 0.98
Sequence Information
- Coding Sequence
- ATGTCTCTAGAGGAGCCAAGAAAAGTACTTGGATTTTTCGAAAGTGAAAGTTTCGAATATAATGTTGAAGTTGGAAAAGTGGAGATTAAAGTACAAAGGAAATGTGGAGAAATTTTCGTTGATGAAAACAATTTATTCAGTTTCTTATGTACACTTTGTAAAGCACCATTTGAAGAAATCTCAAATTTTTTTTTACATATTAAAGAAAATCATACAGTGGAAGATGAAAACATGAAGTGTATGGAGAGGGAAGATGAATACGAAGGGGATAGAGAAGATGAGTACAAGGAGGATAAAGATGATGAATATGAGGAGGATAAAGAAGATGGATACGAGGAGAATAAAGAAAATGAATACGAGGAAGATAAAGAAGATGAATTCGAGGAAGATGAAGAAGATGAATTCGAGGAAGATGAAGATAAATACAAATGGGATAGAGGAGATGAATACAAAAAAGATAGGGAAGATGAACACAAAGAGGATAAAGAAGATGAGCATACACTGGAAGATTTAATGCCATGGTCACCAAATAAAGATGATCCTGAAATTGTAAAATCAATTGTAGAAATAATTGCAATCGATAATATTAACGTGATTCCCGTTATACCTAAATTTACAGAAGATAACTCAAGTGATGAATCAATATTTATTAATATAAATGAAGTTAAAAAGAAACCTCGAAAAAAGAAATTAAAAGATGAAAATGAACAAGTAAACACAAACTCTACATTAACAGTATTTTCGTTTGATGAAGAAACAAATAATATGAAACATAAAAGTGAAAAAGATGAGCTTGATGATATGAAAGATGAAAATGAAGAATATGAAAAAATTTGGCATGATAATATGGAAAATAAAAGTGGAGAAAATGAACAAGATAAACAGGGACCAAAATGTACAATTTGTGGAAAAGTATTTTCACGTGTAGCTTCTTTAAATCGACATAAAAAACTTGTAAAATGTAGTGAAAAACCATTAAAAATAAAAATAGATAAAATAAAAGTATACATTTGTGATATTTGTGGTTTAAGATTTAAATCAAACCGTGCTCTTGAAGAACATAAATATTTTACAAAACGTGGACATAATTTAGGTTCAAATCCACAATATCAATCTGATAAAGCAGTAAAGAAAAAATTAATAAATCTATCAAAAgcatcacaaaatgaaaaattaaaatgtaaatattgtgatagaatttttgtagatacaacaaaacgtgctgatcatgaacgtattcatactggtgaaaaaccatttgaatgtaaaatatgtggtagacgttttcataaaaaatcatattgtcaaatgcatgaacgtacaacacatacaacagaaagattatcaacatgtgaaaaatgtggtaaaacatttaaaaatgaaatagctgttatggcacatatgaaaagacatggtaaaccaaatttacaatgtaattattgtgaaagattattttttaataaagttgaacgtagacaacatgaaagaatacatactggtgaaagaccatatatatgtaaattatgtgataaatcatttcaaactagtggaagtttaagtgaacatcatagaataaaacatttaaatgttagattatattcatgccaatattgtgatagaagtttttatacaaaacaacaattaacaaatcatagtgctgtacataaacgtgatataaaaccatttcaatgtgaattatgtaatacatcatttgcattacgaagaagtttatcattacataaaaaaattcattcaaatgaacgtaattatgtatgtagaatttgtggtCGGGGTTTCAAGCAATATTCTGGATTATATCTTCATAAAAAAAATCATGCTAAAAATACACAAAAAAGATGA
- Protein Sequence
- MSLEEPRKVLGFFESESFEYNVEVGKVEIKVQRKCGEIFVDENNLFSFLCTLCKAPFEEISNFFLHIKENHTVEDENMKCMEREDEYEGDREDEYKEDKDDEYEEDKEDGYEENKENEYEEDKEDEFEEDEEDEFEEDEDKYKWDRGDEYKKDREDEHKEDKEDEHTLEDLMPWSPNKDDPEIVKSIVEIIAIDNINVIPVIPKFTEDNSSDESIFININEVKKKPRKKKLKDENEQVNTNSTLTVFSFDEETNNMKHKSEKDELDDMKDENEEYEKIWHDNMENKSGENEQDKQGPKCTICGKVFSRVASLNRHKKLVKCSEKPLKIKIDKIKVYICDICGLRFKSNRALEEHKYFTKRGHNLGSNPQYQSDKAVKKKLINLSKASQNEKLKCKYCDRIFVDTTKRADHERIHTGEKPFECKICGRRFHKKSYCQMHERTTHTTERLSTCEKCGKTFKNEIAVMAHMKRHGKPNLQCNYCERLFFNKVERRQHERIHTGERPYICKLCDKSFQTSGSLSEHHRIKHLNVRLYSCQYCDRSFYTKQQLTNHSAVHKRDIKPFQCELCNTSFALRRSLSLHKKIHSNERNYVCRICGRGFKQYSGLYLHKKNHAKNTQKR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00235248;
- 90% Identity
- -
- 80% Identity
- -