Basic Information

Insect: Bombylius major
Gene Symbol: -
Assembly: GCA_932526615.1
Location: CAKOBF010000200.1:111686-115138[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 0.85 50 4.8 1.1 2 20 29 47 28 49 0.91

2 17 0.098 5.8 7.8 5.0 1 23 70 92 70 92 0.97

3 17 0.12 7.1 7.5 4.4 1 23 98 121 98 121 0.92

4 17 0.0025 0.15 12.8 0.9 1 23 124 147 124 147 0.97

5 17 0.26 15 6.4 0.6 2 17 156 171 156 176 0.87

6 17 0.0016 0.093 13.4 1.3 1 23 184 206 184 206 0.97

7 17 0.00098 0.058 14.1 1.3 1 23 212 234 212 234 0.97

8 17 9.3e-05 0.0055 17.3 0.8 1 23 240 262 240 262 0.97

9 17 0.048 2.8 8.8 1.3 1 21 268 288 268 289 0.93

10 17 0.027 1.6 9.5 0.9 1 23 632 655 632 655 0.92

11 17 0.0088 0.52 11.1 0.8 2 23 679 700 678 700 0.93

12 17 0.0022 0.13 13.0 1.2 2 23 736 758 735 758 0.96

13 17 0.00013 0.0074 16.9 0.3 2 21 777 796 777 797 0.93

14 17 0.00011 0.0063 17.1 1.2 1 23 805 827 805 827 0.99

15 17 5.1e-06 0.0003 21.3 3.7 1 23 833 855 833 855 0.99

16 17 7.5e-06 0.00044 20.7 0.1 1 23 861 883 861 883 0.98

17 17 0.00049 0.029 15.0 3.0 1 23 889 911 889 911 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	0.85	50	4.8	1.1	2	20	29	47	28	49	0.91
2	17	0.098	5.8	7.8	5.0	1	23	70	92	70	92	0.97
3	17	0.12	7.1	7.5	4.4	1	23	98	121	98	121	0.92
4	17	0.0025	0.15	12.8	0.9	1	23	124	147	124	147	0.97
5	17	0.26	15	6.4	0.6	2	17	156	171	156	176	0.87
6	17	0.0016	0.093	13.4	1.3	1	23	184	206	184	206	0.97
7	17	0.00098	0.058	14.1	1.3	1	23	212	234	212	234	0.97
8	17	9.3e-05	0.0055	17.3	0.8	1	23	240	262	240	262	0.97
9	17	0.048	2.8	8.8	1.3	1	21	268	288	268	289	0.93
10	17	0.027	1.6	9.5	0.9	1	23	632	655	632	655	0.92
11	17	0.0088	0.52	11.1	0.8	2	23	679	700	678	700	0.93
12	17	0.0022	0.13	13.0	1.2	2	23	736	758	735	758	0.96
13	17	0.00013	0.0074	16.9	0.3	2	21	777	796	777	797	0.93
14	17	0.00011	0.0063	17.1	1.2	1	23	805	827	805	827	0.99
15	17	5.1e-06	0.0003	21.3	3.7	1	23	833	855	833	855	0.99
16	17	7.5e-06	0.00044	20.7	0.1	1	23	861	883	861	883	0.98
17	17	0.00049	0.029	15.0	3.0	1	23	889	911	889	911	0.98

Sequence Information

Coding Sequence: ATGAATGAAGACACAACTTCTGGATCTGAAGAATCTGATGTAGAAGAAGAATTTCCATCTAAATCAAAAGAAAATGATGATAAAAGATGTAAATATTGCGTTAAACTTTTTAAAACCTTACAAGAAAAAGAAAAACATGAAGAAAAATGTGAAGCAGCAATTTATAATCCAACTGATATTGTAAGTACAAAAGATGGACAGAACAGTTTCATATGTAATGATTGCTGTCGTACATTTAAATTTTTAACTGGTCTAACAAAACATAAATTAAAACATGAACCACCCGGCGGATTTATTTGTAGAATTTGTGATGCTAAATTTTGTTCAGATTTTGAATTACAAAAGCATAAAGAACATACTCATATGGTTTACAAATGTAGGGTTTGTAAAGGAAAATTTACAAGTAGGGAAAGTTATGAAGAGCATATAATTAAAGAACATGATGGACGTGATCGAGAATATGCTGTTTGTGAAGATTGTGGTGCATTATTTAAAACTCGTACACATTTATCATTTCATAAACAATCAAATTGTGGAACATTAAAACCATATAATTGTGATCAGTGTGGTTCATTTTTTCAAAATAAATGGTCATTAAAAAATCATAAATTAATTCATAGTGGCGAAAAGAAATTTTTCTGTAGTTATTGTGGTAATAGTTTTCTTAATAAAGGACAATTAATAAATCATGAAAGAAAACATACACAAGAGAAACCGTTTGTTTGTGATATTtgctccaaagcatttgctcaccgagaaagtttagttacacattcatcaactcatactggtataaaaccgtatttatgtgaaggatgtggtgcatgtttttcatgtattggaaatttaataaaacatCGACGTAATCGTCCGTTTTCATGTGGTTTACCACAATTTACAAATAAAGCTAAAATAGCACCACGACCAAGTTTCAAATCTGGCAAATTTCAAGCGAAAACTAAAATTCCAAAAACGGGTATGGTGTTGGCTGATGATGCTATTAAAAAAATGAAAAACTTCTTCAAAAGAGAAAAAACAAAAACTGTGAAAAAATGTAGAAAGCAAGAAAGTTTAGAACAAACAGATGAAAAAATTAATTCACATGTTAATAATATCAATGAAGTAAATAAAGAAGAAACTCTTACAGTAGCTAATTATCAAGAAACAGAAATTAGTCAAAGTGATTTTATGGAGGATAACAAAAAGGAACCATTAATACTCTTTGAATCTGAAATTACAGATGAAATGACAACAACGAAAACAGAAACAATTTGTGTTCTTGAAATAATAGACCACGATGAAATTACAAATGATGTTTGCAATGATTTTGAGGATAGTTTTAATGATCATGATTTATCAGACTTTTTTAATTTTGATAATGAAAAACTGGTAAATATTGAAATAAAACAAGAAACAACGGATATCAATCATGATGTTATATTACAAAATACTTCAGATGTTCTTCATGTCGTTAAACAGGAGGATTGTGCCATAAATAATGAAAATTTTTCTAACAAAAAACTAAAAATTGAAAAAGAAGAAAACATTAAAAGTGAAGATGAAGAAGATAATATTCCTTTATCAAGAGTAAAATCAAAAATAAAAACCAGAGAAAATAAAAGGAAAATACCATCAAAATCATCTAAAAATAAGAAAACATCATCAAAATCATCTAAAAATAAGAAAACATCATCAAAATCAACTAAAAATAAAAAATCACTTCCACATGAAAATTTACAGTTACCATCAGTAATCGATAATCAAGAAACAAATGAACATATTAATAATTTAAAAGAAAATCCAGAAAACATTTTAATAATTGCACATAACATTAGTACAGAATATAAACGAAAAACTAAAGAAAAAATGAATACTCCATCAAGACAACAAACATTTGAATGTGATCATTGTCCAAAAATTTACATGCAACGTAAGCCATACGTAAAACATCTTGTTAATGATCATAAAATGAATTTATATGAAATTGAAACATCTTTAGATATATTAAATCAACAAGATAATGCTAAACAAATGCGTTGCAGATATTGTGCTAAAATTTATTATCAAAAAGTATCTTTAAAAAGACACGAAGATCTTCATGGTCCTGAAGGAAAACTAATTTATAAATGTCAGTGTTGTCAAAGTTATTTTGCTACACCAGAAAAGGCAACTGAACATGCTAAAGAAGAACATGAAGATTTATTAAAATGTAATATTTGTAATAAGATTTATAGTTGCCCAGATTCATTGGTTACACATCAAAAAAGTGTTCATTCAACAACAAAAATTGAATTAGATAGTAGCGGTTTTAAAAATAAACCAAATAACGTGTGTCAAAAAtgtggtaaaagatttgttaataaaacggcattaaatgatcatgaaagatcaaattgtggacaaaatccattatataaatgtaaagcttgtggtaaaggttatcatagtgctggttcattaaaaactcatcaaaatattcatactggtgagttaccatataaatgtgaacattgtgataaagcatgccgaacacctggacaacttaaggttcatgaaagaaaacacactggagagaaaccttttaaatgtgaaATTTGTCCAAAAGCATTTGCATACCGTGAAAGTCTTCTAATACACATGAGCCTTCATACCGGTGTTAAACGTTATATATGTTACGGATGTGGTACACGTTTCTCATGCATTTCAAATTTACAAAATCATAGAAGAACACATAAAGATACCTGCGGAGCATTACCGTTAAATTCAAAAGCAAGTATGCCAATGGGTGTTGCTCGTGGTATTTTACATGTTGGTAAAAGATTTGAATAA
Protein Sequence: MNEDTTSGSEESDVEEEFPSKSKENDDKRCKYCVKLFKTLQEKEKHEEKCEAAIYNPTDIVSTKDGQNSFICNDCCRTFKFLTGLTKHKLKHEPPGGFICRICDAKFCSDFELQKHKEHTHMVYKCRVCKGKFTSRESYEEHIIKEHDGRDREYAVCEDCGALFKTRTHLSFHKQSNCGTLKPYNCDQCGSFFQNKWSLKNHKLIHSGEKKFFCSYCGNSFLNKGQLINHERKHTQEKPFVCDICSKAFAHRESLVTHSSTHTGIKPYLCEGCGACFSCIGNLIKHRRNRPFSCGLPQFTNKAKIAPRPSFKSGKFQAKTKIPKTGMVLADDAIKKMKNFFKREKTKTVKKCRKQESLEQTDEKINSHVNNINEVNKEETLTVANYQETEISQSDFMEDNKKEPLILFESEITDEMTTTKTETICVLEIIDHDEITNDVCNDFEDSFNDHDLSDFFNFDNEKLVNIEIKQETTDINHDVILQNTSDVLHVVKQEDCAINNENFSNKKLKIEKEENIKSEDEEDNIPLSRVKSKIKTRENKRKIPSKSSKNKKTSSKSSKNKKTSSKSTKNKKSLPHENLQLPSVIDNQETNEHINNLKENPENILIIAHNISTEYKRKTKEKMNTPSRQQTFECDHCPKIYMQRKPYVKHLVNDHKMNLYEIETSLDILNQQDNAKQMRCRYCAKIYYQKVSLKRHEDLHGPEGKLIYKCQCCQSYFATPEKATEHAKEEHEDLLKCNICNKIYSCPDSLVTHQKSVHSTTKIELDSSGFKNKPNNVCQKCGKRFVNKTALNDHERSNCGQNPLYKCKACGKGYHSAGSLKTHQNIHTGELPYKCEHCDKACRTPGQLKVHERKHTGEKPFKCEICPKAFAYRESLLIHMSLHTGVKRYICYGCGTRFSCISNLQNHRRTHKDTCGALPLNSKASMPMGVARGILHVGKRFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00234220;
90% Identity: iTF_00234220;
80% Identity: -