Basic Information

Gene Symbol
-
Assembly
GCA_939192785.1
Location
CALNDV010001855.1:34623-37919[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.69 40 4.9 1.1 2 20 28 46 27 48 0.91
2 17 0.08 4.6 7.9 5.0 1 23 69 91 69 91 0.97
3 17 0.097 5.6 7.6 4.4 1 23 97 120 97 120 0.92
4 17 0.0041 0.23 11.9 0.9 1 23 123 146 123 146 0.96
5 17 0.21 12 6.5 0.6 2 17 155 170 155 175 0.87
6 17 0.0013 0.074 13.5 1.3 1 23 183 205 183 205 0.97
7 17 0.0019 0.11 12.9 3.0 1 23 211 233 211 233 0.97
8 17 7.4e-05 0.0042 17.4 0.8 1 23 239 261 239 261 0.97
9 17 0.039 2.2 8.8 1.3 1 21 267 287 267 288 0.93
10 17 0.39 23 5.7 0.9 1 23 629 652 629 652 0.85
11 17 0.00085 0.049 14.1 1.2 2 23 676 697 675 697 0.96
12 17 0.38 22 5.7 1.5 1 23 705 728 705 728 0.94
13 17 0.0012 0.068 13.6 1.6 2 23 733 755 732 755 0.96
14 17 0.0001 0.0059 17.0 0.3 2 21 774 793 774 794 0.93
15 17 1.8e-05 0.001 19.3 1.3 1 23 802 824 802 824 0.99
16 17 4.2e-06 0.00024 21.3 3.7 1 23 830 852 830 852 0.99
17 17 1.2e-05 0.00068 19.9 0.2 1 23 858 880 858 880 0.98

Sequence Information

Coding Sequence
ATGAATGAAGACACAACGTCTGGATCTGAAGAATCTGATGTAGAAGAATTTCCATCTAAATCAAAAGAAAATGATGATAAAAGATGTAAATACTGCGTTAAACTTTTTAAAACCTTGCAAGAAAAAGAAAAACATGAAGAAAAATGTGAAGCAGCAATTTATAATCCCATTGACATTGTAAGTACAAAAGATGGACAAAATCGTTTCATATGTAATGATTGCTGTCGTACATTTAAATTTTTAACTGGTCTAACAAAACATAAATTAAAACATGAACCACCCGGCGGATTTATTTGTAGAATTTGTGATGCTAAATTTTGTTCAGATTTTGAATTACAAAAGCATAAAGAACATACTCATATGGCTTACAAATGTAGAGTTTGTAAAGGAAAATTTACAAGTAAAGAAAGTTATGAAGAACATGTAATTAAAGAACATGATGGACGTGATCGAGAATATGCTGTTTGTGAAGATTGTGGTGCATTATTTAAAACTCGTACACATTTATCATTTCATAAGCAATCAAATTGTGGAACATTAAAACCATATAATTGTGATCAATGTGGTTCATTTTTTCAAAATAAATGGTCATTAAAAAATCATAAATTAATTCATAGTGGTGAAAAGAAATTTTGCTGTAGTTATTGTGGTAACAGTTTTCTTAATAAAGGACAATTAATAAATCATGAAAGAAAACATACACAAGAGAAACCGTTTGTTTGTGAGATTTGCTCCAAAGCATTTGCTCACAGGGAAAGTTTAGTTACACATTCATCAACTCACACTGGTATAAAACCGTATTTATGTGAAGGATGTGGTGCATGTTTTTCATGTATTGGAAATTTAATAAAACATCGACGTAATCGTCCGTTTTCATGTGGCTTACCACAATTTACAAATAAAGCTAAAATAGCACCTCGACCAAGTTTCAAATCTGGTAAATTTCAAACAAAAACTAGAATTCCAAAAACTGGTATGGTTTTAGCTGATGATGCTATTAAAAAAATGAAAAGTTTTTTCAAAAGAGAAAAAACAAAAACCGTGAAAGGTACGAAAAAATGTAGAAAGCAGGAAAATTTAGAACAAACGACTGAGAAAATTAATTCAGATATTAATAATATCAACGAAGTAAATAAAGAAGACATTTTTACAATAGCTAATTATCAAGAAACAGAAATTAGTCAAAGTGATTTTATTGACGATAACAAAAAGGAACCATTAATACTCTTTGAGTCTGAAATTACAGATGAAATGACAACGACGAAAACAGAAACAATTTGTGTTCTTGAAATAATTGACCCGAATAAAATTACAAACGATGTTTGCAATGATTTTGAAGATAGTTTTAATGATCATGATTTAACAGACTTTTTTAATTTTGATAATGAAAAACTAGTAAATATTGAAATAAAACAAGAAACAACGGATATCAATCATGATGTTATATTACAAAATACTTCAGATGTTCTTCATGACGTTAAACAGGAGGATTGTGCCATAAATAATGAAAATTGTTCCAATAAAAAACGAAAAATTGAAAAAGAAGAAAAAATTAAAAGTGAAGATGAAGAAGATAATATTCCTTTATCAAGAGTTAAATCAAAAATAACAACCAGAGAAAATAAAAGGAAAATACCATCAAAATCATCTAAAAATAAGAAAACACTATCAAAATCATCTAAAAATAAGAATAAAAATAAAAAATCACTGCTACATAAAAATTTACAGTTATCATCAGTAATCGATAATAATCAAGAAACAATTGAACATATTAATAATTTAGAAGAAAATCCAGAAAAAATTTTATTAATTGCACATAATATTAGTGCAGAACGTAAACGAAAAACTAAAGAAAAAACTAATACTCCATCAGGACAACAAATATTTGAATGTGATCATTGTCCAAAAATTTACTTGCAACGTAAACCATACGTAAAACATCTTGTTAATGATCATAAAATGAATTTATATGAAATTGAAACATCTTTAGATATATTAAATGAACGAGATAATTCTAATCAAATGCGTTGCAAATATTGTGCAAAAATTTATTATCAAAAAGTATCTTTAAAAAGACACGAAAATCTTCATGGTCCTGAAGGAACACTAATTTATAAATGTCAATGTTGTCAACGTTATTTTTCTACACCAGAAGAAGCAACTGAACATGCTAAAGAAGAACATGCAGATTTATTAAAATGTAATATTTGTAACAAAATGTATAGTTGTCCAGATTCATTGGTTACACATCAAAAAAGTGTTCATTCAACAACAAAAATTGAATTAGATAGTAGCGGTTTTAAAAAGAAACCAAATAATGTatgtcaaaaatgtggtaaaagatttgttaataaaacggcattaaatgatcatgaaagatcaaattgtggacaaaatccattatataaatgtaaagtttgtggtagaggttatcatagtgctggttcattaaaaactcatcaaaatattcatactggtgaattaccatataaatgtgaacattgtgataaagcatgtcgaacacctggacaacttaaggttcatgaaagaaaacacactggagagaaaccttttaaatgtgaaATTTGTGAAAAAGCATTTGCATACCGTGAAAGTCTTCTAATACACATGAGCCTTCATACCGGTGTTAAACGTTATATATGTTACGGATGTGGTACACGTTT
Protein Sequence
MNEDTTSGSEESDVEEFPSKSKENDDKRCKYCVKLFKTLQEKEKHEEKCEAAIYNPIDIVSTKDGQNRFICNDCCRTFKFLTGLTKHKLKHEPPGGFICRICDAKFCSDFELQKHKEHTHMAYKCRVCKGKFTSKESYEEHVIKEHDGRDREYAVCEDCGALFKTRTHLSFHKQSNCGTLKPYNCDQCGSFFQNKWSLKNHKLIHSGEKKFCCSYCGNSFLNKGQLINHERKHTQEKPFVCEICSKAFAHRESLVTHSSTHTGIKPYLCEGCGACFSCIGNLIKHRRNRPFSCGLPQFTNKAKIAPRPSFKSGKFQTKTRIPKTGMVLADDAIKKMKSFFKREKTKTVKGTKKCRKQENLEQTTEKINSDINNINEVNKEDIFTIANYQETEISQSDFIDDNKKEPLILFESEITDEMTTTKTETICVLEIIDPNKITNDVCNDFEDSFNDHDLTDFFNFDNEKLVNIEIKQETTDINHDVILQNTSDVLHDVKQEDCAINNENCSNKKRKIEKEEKIKSEDEEDNIPLSRVKSKITTRENKRKIPSKSSKNKKTLSKSSKNKNKNKKSLLHKNLQLSSVIDNNQETIEHINNLEENPEKILLIAHNISAERKRKTKEKTNTPSGQQIFECDHCPKIYLQRKPYVKHLVNDHKMNLYEIETSLDILNERDNSNQMRCKYCAKIYYQKVSLKRHENLHGPEGTLIYKCQCCQRYFSTPEEATEHAKEEHADLLKCNICNKMYSCPDSLVTHQKSVHSTTKIELDSSGFKKKPNNVCQKCGKRFVNKTALNDHERSNCGQNPLYKCKVCGRGYHSAGSLKTHQNIHTGELPYKCEHCDKACRTPGQLKVHERKHTGEKPFKCEICEKAFAYRESLLIHMSLHTGVKRYICYGCGTR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00235240;
90% Identity
iTF_00235240;
80% Identity
-