Bmaj015105.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombylius major
Gene Symbol
Rfx2
Assembly
GCA_932526615.1
Location
CAKOBF010000408.1:12231-22983[+]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1.8e-37 1.9e-33 115.1 0.1 3 78 292 367 290 368 0.97
2 2 2 2.1e+04 -4.2 0.7 69 75 745 751 741 754 0.74

Sequence Information

Coding Sequence
ATGACAACTAGACTTGCAACACAACGAAATTATGTTACAATTACTACAGCAACAAATCCTAAAGATTCTAATTCAAGGAAATCAAATCCTTCAACAGTGACACCTACAACTGGAGAACTAATTACAATAACATCCGCAGGATCTACAGAACAAAAAAATTCATCTAGTCAAACAAATGTGATACCATTGCAACAAGTTTTAACACAGAAGAAATTACTTCTTCAAACTGATTCATCTGGAGTAGCTGTAATTGATGTATTACCATTAGATTCATCTGAATCAAATAGTACATCACCAACTCACATAACAACTGATGTTGCCGGTATAGAGTCAGAATTATCACCAACAGATAGTACATCATCATCATCTCTGTCTCAACAGGTTGGTGGTACACAAGTAACTGTGGTACAATCACAAAGTCCAAATGAAAATTCCAGTCAACAACGTTTCATTACTGTAACTGTTTCGACAGATAATAGCGGAAATCAAGAATCATATCAAGTGCAATATGTCGATCCTGAATTATATCATGGAACGGCTCAAAGCCAAAATCAAATGAATTATCCATTTTGTGCAATTGGAGATTATCAAACAAATAATCAATCATATTATACAACAACTGGTAATTATACGAATGCAACGAATACTGCAGCAACATCTCACTCATCTACTTTGCCTTATATAGTTCCTGTTGATGAAAGTTTACTATTAACATCATCACAAAATCGTGATTCACCACAAAATTTAAGAACGGAGGTAACTTACATTCAAGAAAATCATAATACACAACAAACACCTTCTTCAACAACTTCAACAACAGTTTCAGAATCTGAAAATACTCCAAGCATTTCACATGTAACAAGAATTTCTCCAGCAACGGTTTCATGGCTTTTGGAAAATTATGAAACAGCCGAAGGTGTAAGTCTTCCTCGTTCAACACTTTATAATCATTATATGCAACATTGTAATGAAAATAAATTAGATGCAGTTAATGCAGCAAGTTTTGGTAAATTAATACGTTCTGTATTTACGGGATTACGTACACGCCGTTTAGGTACAAGAGGAAATTCAAAATATCATTATTATGGTATACGTGTTAAACCTGGTTCATCATTTGTACAAACAATAGAAGAAAAATCACAAAATTATCCAGGAAATTCAAATATGAATAATAAAAGTAATATTAAGAAACATGGTGCAAAACCAGAAGCATATGAAGCATGTTCACAGTTCTTAGGTGATGGTTCCGGAGCTATACCAATATTTCCAAACATTGAAAGAGATTCAACAATGTCAAATGATATAACAATGGAAGATATTGAAATATTTCGTTCAATGTATCGTGAAAATTGTGAATTATTTCTGGAAGCTATATTAAATTTAGAATTTAGTACAATTGAATTATTATGGAAAGATTTTTGGCGTTCATCTGATAATAATAATATCGATGAAAGTGAAGAAGAAAAATATCTAAGCAAAGCAAAATTATATTTATTATGTCAATATAAAAGTGTACAAGATTTTGTAAAAGAGGTCGATTTTACATTTTATCAAAATATGGTTGAAGTCCTTATTCCTGATGTACTTCGTTCAATTCCTAATTCATTAACACAAGCTATTAGAAATTTTGCAAAAAATCTTGAAATTTGGTTATCTGAAGCTATGAATGGATGCCCAGAAAAAATAATTAAAATAAAACATTCCGCTGTATCAGCATTTTGTCAAACATTAAGACGTTATACCTCATTAAATCATTTAGCTCAGGCTGCAAGAGCTGTTTTACAAAATAGTTCACAAATAGCACAAATGTTAAACGATTTAAATCGTGTTGATTTTCATAATGTTCAAGAACAAGCAGCTTGGGTATGTCAATGTGATACAGCAACCGTCCAACGTTTAGAAAACGATTTTAAATCAGCATTACAACAACAAAATTCATTAGAACAATGGGCCGCATGGTTACGTTCAGTTGTTAATTCAACATTAGAAGAATATCGTGGTAAACCAAATTATGCAAAAGCAGCTCGACAATTTCTATTAAAATGGAGCTTTTATAGTTCAATGGTAATACGTGATTTAACATTACGTTCAGCATCAAGTTTTGGTAGTTTTCATTTAATACGACTTCTTTATGATGAATACATGTTCTTTTTAATTGAACATAAAGTTGCAGAAGCACAACAAACAACAGCTATTGCTGTTATAAGTGAATATGATAAACAGGTAAGTAAAAGTTATCATTATAATAATATATATCATCATAATAATGATAGTTTACAAAATCTTAATGATAATAACATTGATATTGATATTGATATGAATTATTCATTTTAA
Protein Sequence
MTTRLATQRNYVTITTATNPKDSNSRKSNPSTVTPTTGELITITSAGSTEQKNSSSQTNVIPLQQVLTQKKLLLQTDSSGVAVIDVLPLDSSESNSTSPTHITTDVAGIESELSPTDSTSSSSLSQQVGGTQVTVVQSQSPNENSSQQRFITVTVSTDNSGNQESYQVQYVDPELYHGTAQSQNQMNYPFCAIGDYQTNNQSYYTTTGNYTNATNTAATSHSSTLPYIVPVDESLLLTSSQNRDSPQNLRTEVTYIQENHNTQQTPSSTTSTTVSESENTPSISHVTRISPATVSWLLENYETAEGVSLPRSTLYNHYMQHCNENKLDAVNAASFGKLIRSVFTGLRTRRLGTRGNSKYHYYGIRVKPGSSFVQTIEEKSQNYPGNSNMNNKSNIKKHGAKPEAYEACSQFLGDGSGAIPIFPNIERDSTMSNDITMEDIEIFRSMYRENCELFLEAILNLEFSTIELLWKDFWRSSDNNNIDESEEEKYLSKAKLYLLCQYKSVQDFVKEVDFTFYQNMVEVLIPDVLRSIPNSLTQAIRNFAKNLEIWLSEAMNGCPEKIIKIKHSAVSAFCQTLRRYTSLNHLAQAARAVLQNSSQIAQMLNDLNRVDFHNVQEQAAWVCQCDTATVQRLENDFKSALQQQNSLEQWAAWLRSVVNSTLEEYRGKPNYAKAARQFLLKWSFYSSMVIRDLTLRSASSFGSFHLIRLLYDEYMFFLIEHKVAEAQQTTAIAVISEYDKQVSKSYHYNNIYHHNNDSLQNLNDNNIDIDIDMNYSF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00233653; iTF_00118432; iTF_01518626;
90% Identity
iTF_00233653;
80% Identity
-