Basic Information

Insect: Bombylius discolor
Gene Symbol: Zfy2
Assembly: GCA_939192785.1
Location: CALNDV010000344.1:29584-46227[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 16 0.099 5.7 7.6 0.7 3 23 319 341 317 341 0.91

2 16 3.6 2.1e+02 2.6 0.3 2 23 412 432 411 432 0.93

3 16 1.5 86 3.9 2.0 3 22 498 517 496 520 0.90

4 16 0.02 1.1 9.8 1.1 2 19 542 559 541 562 0.93

5 16 0.02 1.2 9.7 2.5 1 23 579 602 579 602 0.95

6 16 0.13 7.7 7.2 1.1 1 20 607 626 607 631 0.81

7 16 0.14 7.9 7.1 1.0 2 23 646 668 646 668 0.96

8 16 0.0014 0.083 13.3 0.1 2 21 674 693 673 694 0.94

9 16 0.061 3.5 8.2 0.8 2 23 859 880 858 880 0.91

10 16 0.35 20 5.9 5.9 2 23 894 914 893 914 0.95

11 16 4.8e-05 0.0028 18.0 3.0 1 23 920 943 920 943 0.95

12 16 6.5e-07 3.8e-05 23.9 1.2 1 23 967 989 967 989 0.97

13 16 2.8 1.6e+02 3.0 0.1 1 23 996 1020 996 1020 0.80

14 16 0.13 7.4 7.2 1.3 1 23 1026 1050 1026 1050 0.97

15 16 0.0056 0.32 11.5 1.1 2 23 1057 1078 1056 1078 0.97

16 16 0.00022 0.013 15.9 2.4 1 20 1084 1103 1084 1105 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	16	0.099	5.7	7.6	0.7	3	23	319	341	317	341	0.91
2	16	3.6	2.1e+02	2.6	0.3	2	23	412	432	411	432	0.93
3	16	1.5	86	3.9	2.0	3	22	498	517	496	520	0.90
4	16	0.02	1.1	9.8	1.1	2	19	542	559	541	562	0.93
5	16	0.02	1.2	9.7	2.5	1	23	579	602	579	602	0.95
6	16	0.13	7.7	7.2	1.1	1	20	607	626	607	631	0.81
7	16	0.14	7.9	7.1	1.0	2	23	646	668	646	668	0.96
8	16	0.0014	0.083	13.3	0.1	2	21	674	693	673	694	0.94
9	16	0.061	3.5	8.2	0.8	2	23	859	880	858	880	0.91
10	16	0.35	20	5.9	5.9	2	23	894	914	893	914	0.95
11	16	4.8e-05	0.0028	18.0	3.0	1	23	920	943	920	943	0.95
12	16	6.5e-07	3.8e-05	23.9	1.2	1	23	967	989	967	989	0.97
13	16	2.8	1.6e+02	3.0	0.1	1	23	996	1020	996	1020	0.80
14	16	0.13	7.4	7.2	1.3	1	23	1026	1050	1026	1050	0.97
15	16	0.0056	0.32	11.5	1.1	2	23	1057	1078	1056	1078	0.97
16	16	0.00022	0.013	15.9	2.4	1	20	1084	1103	1084	1105	0.95

Sequence Information

Coding Sequence: ATGCTGGAGGAAGATATCGATGATACACATCTTTGTATTAAATGCAGTACAACAATTGTTGGTATTGAAAATTATGTACAACATAGAAAAAATTCATGTTCATCAAAAACAAATCGTGATATACGAGTAGTTCATGTTGATCATCCGTATGGTACATATGACTTTTCTGAAACATCAACATATCATCATCATGACCATCATAAATCTGAAGAAGTTGAAAAACCAGGAAAATCATTATCAGAATCTTATGATCTACCTTATGATTTGGGTGCGGATGTATTTTTTTCATCATTAGAGCTTCAAAGTAGCTCAAAACGTACTTTACGTAATGTTAATGCTACTACTACTAGTAATAATGGTATTAGTAGTGGTAAACATTCTTCAACGACATCATCACGTATATTAACACGTAAAGCTACTGCTGCATTATTAGCACATCATGAACAAGAAGATGAATGGATTGAACAAACATCATCTACACCAAATAATAATTCTCACAATTTAATGATAAGTGGTAATAAAAAATGTGAACCGCCATCATCGGTTTTCACATTTAATCATGATTCACCTGAACCAGAAACTGAAGATGAAGATGATGTTGATGATGAAGATTATGAAACAACCAGTCCAAGTGTTCCAGCAAATCATACTGGCGGTAAATGGAAGCCGACAGATAATAATGGTGGTAATTTAAGACAACATCACGATCATCATACATTATTGAGAAATTCACCATCATCAGCTTGGGATGATCGACATCATACTTGGGATAGTATAACAGATACAGTTGATGAAAAATCTGGAAAAATTCAAGAAATACATGAAGATTTTGATCATGATTTTAATCCACCACCAGGACATACTAAAGGTAAATGGGTACCTGGTACGAAAATTGTGAAACTTGATTATAAAGAAGAAGTTGAAATTGAAAGAATTTATACACGTCAATATTGGTGTAATACATGTAATCGTAAATTAGCATCAAAAATATTATATGAACGTCATTTAAAATCAAATCTTCATTTGAAAAGATCCGAACCAGAACAACAACTTGAAAGAGCTGCCGTTAAAATGATTACACTTCCAGAACGAATTAAAAAACCATCAAAATATTTAAATTCATCAATTTATGTGACATCCTCAACAAAATCTGATATCTCAGAGAAAAAATCAAAAACTACAATTAGTTCCGAAAAATTATCAGAAAAACGAAAACGTCGAAAATACTACATAAAATGTGAAACATGTAAGATAAGACTACCAAAATATTCACTTGGAAAACATTTAATATCACATTATCATTATCGACGTATGATTCAGAGTCCATCAAAATCTTATGATATGATTCTTGAGAATATGGATAGAATTGTAAAACAAGCACCATATCAATGTCAACCATGTCAGTTCTATACAAATACTGAAAATGATTTCTTATGTCATTGGAATACACCAAATCATCGTGATATCACTGAGGGTCCTGGTAGATTTTGGTGTAGTTTTTGTAAATTTGAATGTGAAGATAATAATCAAATGAGACGTCATTTATTAAGTATTGAACATAAAGAAGTTGTATTAACTATTAATCGTTCTGTACCAATTATAATTGGTAAAAAAATAATTATTGAATGTTTTAAATGTAAACAAATATTTCGTTATAATTTTGAATTACGTAAACATGCTGAACATTGTACTGCTGAACCAACTGGTACAGCATCAAATAATTATCAATCAAAATTTAATTGTAATTTATGTGATGTTATTTGTAAATCACGTTTATCATTACAAAAACATCAATTATTAAAACATAAAAAGAAAAATTTTTATTGTTCAATATGTAATAAAAATTTTGAAACAGCATTAAAATCTAAAAAACATCGATCATCAATTGAACATAAAATTTGTGCATCATCGAAAAAACATAAAATTTTAATAAGAAAATGTAAAATTTGTAATGAAACTTTACAAGACATATTAAAATTGAAGGAACATATGAAATTAAAACATCCAGAAAGTAAATCTTCGTGTCCTCATTGTGGTAAAACTTTCGCTTTACCGCAAGAAGTTGGTCGTCATATTCGAGATATGCAGTGTAACCAGTCGAAAGAATTGCATTTATCAGGACTATTAGAATCAGATGAAACAATTTCGGTAGCTCCTACTCCGTGTTCTACTACATCATCTTCATCCTTGAATACAGTTCGTCCTACTACATCAAACATCTCTTCGTCTTCTTCTCTGACAAATCCTGAATCCACTCCTCTATATTTATCAACAATGTCACTAGCATCATCGAAAACAGTTCTTTCCACAACTAATTCCTTATTCCTTACAGTACCATCAACATGTTCTACAGTACTGAATCCACCACTTCTTTCTACCGTAAACAGTCCTCTGTTTCTGACGATTTCTTCAACATCTTTAACACGACAAGATATTACACACGATACAGTTATTTCAAGTCCAATTGTAGTTGAACACATCACAAAAACTAAAAAATTATATTCATCAACAAATGATAATAATGAATCCAATGACATCACAAAAGGAACACAAACTGAAAACGATAAAATGTTATCCTGTTCGAAATGTGATTACAGAACAACAATGAAATCGGAACTTTTATATCATGAAATTTTTCATAAACAAGAAAATTTAAATTCAAATAAAAAATTAAAAATATCATGTCCATTATGTGAAAAAAAATTTCGAAAACATTCATTAAGATGTCATTTACGTCAACATACTAATGAGAAAAATTTTATATGTAATTACTGTCAAATGAGTTTTGGTCGAAAACATAATTTAAAGACACATATCATAAATCGGCATGAAACTGATAAAAAACAACAAAAACAACAAAATATAAAAAAAAATCCTAATAATAAAATACAAGCAAAATATCAATGTGATACATGTGGAAAATCCTTTAAAAAAAGATATTCACTTCAACAGCATATTGGCATACATGGTGAACGTGACAAAAGATTCAGTTGTCCAAAGGAATTATGCATTTTTATTGGTAGAGATGCATCAGATTTAAAAATTCATTTAAGTGTACATTCAATGGAGAAAAATTTTAAATGTACATACGATGGATGTGATTATATGGGAAAAACTATGAGACTTTTAAAAAAACATTCCATAAAGCATGAATCAAATAAAATATTATCATGTCCAGAATGTAATTTTACTGCTAAACTTTCAGGACATATAAAACGTCATATGCTTACTCATACTGGAGAAAAACCTTATAAATGTCCACATTGTTCTTATTCTTGTAATAATTTGGAAAATTTAAGAAAACATGTTTTATTAACTGCATTACATACCGGTAAATATTTATATGAATGTGAATTTTGTGATACAGAACAAAAATTTAAAACGAATTTTCAACGTGAATATCGTGCACATTTAGTTATTGCTCATAGAGTTGAAGTTGAAAAATTAAAAAAATTAATAaacactttgcataatgatgcgttttctcgttga
Protein Sequence: MLEEDIDDTHLCIKCSTTIVGIENYVQHRKNSCSSKTNRDIRVVHVDHPYGTYDFSETSTYHHHDHHKSEEVEKPGKSLSESYDLPYDLGADVFFSSLELQSSSKRTLRNVNATTTSNNGISSGKHSSTTSSRILTRKATAALLAHHEQEDEWIEQTSSTPNNNSHNLMISGNKKCEPPSSVFTFNHDSPEPETEDEDDVDDEDYETTSPSVPANHTGGKWKPTDNNGGNLRQHHDHHTLLRNSPSSAWDDRHHTWDSITDTVDEKSGKIQEIHEDFDHDFNPPPGHTKGKWVPGTKIVKLDYKEEVEIERIYTRQYWCNTCNRKLASKILYERHLKSNLHLKRSEPEQQLERAAVKMITLPERIKKPSKYLNSSIYVTSSTKSDISEKKSKTTISSEKLSEKRKRRKYYIKCETCKIRLPKYSLGKHLISHYHYRRMIQSPSKSYDMILENMDRIVKQAPYQCQPCQFYTNTENDFLCHWNTPNHRDITEGPGRFWCSFCKFECEDNNQMRRHLLSIEHKEVVLTINRSVPIIIGKKIIIECFKCKQIFRYNFELRKHAEHCTAEPTGTASNNYQSKFNCNLCDVICKSRLSLQKHQLLKHKKKNFYCSICNKNFETALKSKKHRSSIEHKICASSKKHKILIRKCKICNETLQDILKLKEHMKLKHPESKSSCPHCGKTFALPQEVGRHIRDMQCNQSKELHLSGLLESDETISVAPTPCSTTSSSSLNTVRPTTSNISSSSSLTNPESTPLYLSTMSLASSKTVLSTTNSLFLTVPSTCSTVLNPPLLSTVNSPLFLTISSTSLTRQDITHDTVISSPIVVEHITKTKKLYSSTNDNNESNDITKGTQTENDKMLSCSKCDYRTTMKSELLYHEIFHKQENLNSNKKLKISCPLCEKKFRKHSLRCHLRQHTNEKNFICNYCQMSFGRKHNLKTHIINRHETDKKQQKQQNIKKNPNNKIQAKYQCDTCGKSFKKRYSLQQHIGIHGERDKRFSCPKELCIFIGRDASDLKIHLSVHSMEKNFKCTYDGCDYMGKTMRLLKKHSIKHESNKILSCPECNFTAKLSGHIKRHMLTHTGEKPYKCPHCSYSCNNLENLRKHVLLTALHTGKYLYECEFCDTEQKFKTNFQREYRAHLVIAHRVEVEKLKKLINTLHNDAFSR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00235373;
90% Identity: iTF_00235373;
80% Identity: -