Basic Information

Gene Symbol
-
Assembly
GCA_011952255.1
Location
NW:68063-75989[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.033 2.1 8.2 0.5 2 21 109 128 108 129 0.93
2 13 0.005 0.33 10.8 0.4 1 21 135 155 135 156 0.96
3 13 0.012 0.78 9.6 5.7 1 23 166 189 166 189 0.93
4 13 3.6e-06 0.00023 20.7 3.0 1 23 546 569 546 569 0.96
5 13 1.2 78 3.3 0.3 5 23 576 595 575 595 0.94
6 13 0.00051 0.033 13.9 1.2 2 23 602 623 602 623 0.96
7 13 1 67 3.5 3.3 1 20 650 669 650 671 0.89
8 13 0.0005 0.033 13.9 2.0 1 22 772 793 772 793 0.96
9 13 2.8e-05 0.0018 17.9 1.2 2 23 801 823 800 823 0.94
10 13 0.62 40 4.2 6.6 1 23 833 856 833 856 0.95
11 13 0.87 57 3.7 0.6 3 19 877 893 875 895 0.93
12 13 0.07 4.5 7.2 4.1 1 23 903 926 903 926 0.90
13 13 0.0011 0.073 12.9 4.9 1 23 937 960 937 960 0.94

Sequence Information

Coding Sequence
ATGGCTCGAGTGTTAGTTTACGCACGCCCTGTTGATGCGATCTTCATGGATATAAAATTGGGCAGCAAAACAGATcCTTCTGAATATGCAATAAGAATAAAGGAAGAGCCAATCGATCCAGAGATCTGCGATGATTTATCGCCAGTTGATACGAATACAGAGAATGAAAATGAGACAGCGATGTGTGAAGGTGAATCTTCGGATGGTGTTTATTGTAGAAATCGAGAATCCGCGTTTCCTCGAGAGAGTACATacttagaaaataacaaatcgGATCCTGATAAACGAAAAAGTAAACATAAAGTACCTTCAAACAACAGAATAAGTTGcaatgtttgtttgttaaCTTTTCAAACTAAACATTTATTGGAACtgcattataaattatatagcTGTAATGTATTCAAGTGTAATAATTGCACTGCGATCTTCAGTATGCATATTGCGTTGATACGTCATTTAAAGTCACGATGTCGTACGAAACAATGGTCTGGATATAGATGTAATTTTTGTAACCGAAGTTTTTCCTATAGAAGATATATCCAATCTCATTTATTCCATATGCATGGGAACGCAATATTGTCTGGTGAAAGCAAAATTACGAAAACATCTCCTGAATCGTTAGGAAAGTCGAATCATTCGGATGATATAGTCATGGCAGAATCAAATACTTCACACAGTTCCTCCCCAAAAAGCGTAAATAGCtcgataaatatatctttgaaACTATCTAATAGTTCAAACGATACACCCACCAAGGGTTCGGGCAGCAAGATCAAGTCTACGCATCCGAAATGGTTAAACGATTCGTATGGTACACCTTCGAAAAGGATGAAACAGACCGTCCTTACAGACTTTATATCGCTGTACAAAGATAAACCGAATGAAAAATGGGTTAGCCCGAAAGAAGTTATCGATACGGAGAATATTCCTGTTACTGCGACTATTATTCCAACTTCAACGCTCGAGACATTTAGCAACAAGACATCAACGGCTTCAGATGTTATCCAGATGTCTACTTCTGTTAAGCGAATCGAATCTCCTGTTAGGAAAAGACCATTTGTTCAGATTCATGTGAATTCCAAAACAATGATATCTTTATTAAGGAACGAAATAGGAGCTGAATCTGAAGGCTCTAATACCTCGCACAATATATCTTACAACCTTAGGCCAGTAAAAAgatgttcttcttctttatataatttttacgatttattgGAGTTTGAGGCCTTTGGAAGATCAAGACaatcttttaaaagaaacaagtCCCGCTATCCGTTTAACCAAAGTGAAAGATCTGCATCTGAAGCTAAGTGTAAAGAATGTGTGGTCCGTTTGGAGAAATGCGACAAATTCTTGGAGCCTACTAGTTTTGTGTCGAATGGAGACAAAGAtgaaaaggagaaggaaaacGAAAACGAAGACGGTTTCAAACAAGCAGTATCGAAAAATGTGAAAGAGAAATTTGAAGGTTTTCGTGAGACAAGCTCGGCAGGTAATTTGCCTTTGGAAACTGGCACGATTGCGTCAAAGCGATTCAAtgaatttgtaaaatcttTCGTTCATAGATTAATCGTACCTCGACAAGAATCGGTAGAGTTTAAGAAGAACTCTAAGGTCGATCagcagaaaatatttcaatgtcatatttgtaaaaaatcgTTTTCTTTGAAAGAGAACTTGCGCGAGCACGTGAAATTGTCCCATGCGATTTACATGTCGAGCATATGCAACGCACGTTACACGTCCATGAATAAGTTACTAACTCACTATCTACGCCAGCATATTGTGTTTAAACGAAGGGAATGTTGCGTGTGTTATGAGAAGTTTGACACGTCGGCATTGTTGAAGCGGCACATGATATTGCATTGTTTGAAGACCATAAGATCAAAGAAGGACGTTCTACCGGTTGATgttgaaataaattgcaaCGCATTCAAGAAACAACACAAATGCCAAGGTTGTCGCAAACGATTTTGGCTATACTCGTGTTTGAAACAGCATGAGAATGTATGTCGTCGAATGAAAGTCTCGATACATAAACAACGTGTACCTCGTGTAAACCATCTGTCTCGGTCGTTGAAAGAACCAAGTGACATGGAACTCGGCATAGTACAATCGTCTGATTTGGAACAAACGTTGGATGTTCCGGATGGGATGACAAGACctttggaaaattatttggCTCCGAGTACGCTTATTACGGATGATACTAACTCTTCGTCATTCGATACAGCTGCAAAGAACAAAAGGCTACTTAATGGAATAGCATGCGTGAAGGGTTACCAAGCGGACAAGATGAACGGAACAAAGTTTCCTTGCACTACTTGTGGGACACAATTCCGAACATTTCAAAATTTGTGCATACACGAGCGCACTTATTGCCAAACAGCCACCAAAAAGTGTAACGTTTGTAACACGATGTTTTCCACTAAAAGATTATTACAGCTTCACATGCTTGCTACCCATACGCCTTCGTGCTCGATGAACTACAAATTCTTTTGTAAGTTCTGTAATCAAGGATTTGTTAAGAAATCGAAAGTTCACATTCACGAACGACACTTCCATATTGGAGAGAATCCTAGACTGGGGCTGAATTCCGATTGCGTTTTGAAAGATAAACAAATCTGTAATATATGCCATTTGTTATTCGAATCCTACGAACATTTTGTCGAGCATAACACGTATTATTACAAGGACAAAGATTTTTTATGCGCAGTATGTGGTAAGTCGTTTAAAGGAATGTACAAGTTTCATCATCACAACAAGTTGGAGCATTATTCGGACAAACTATGGAAATTGTACCCTTACAAATGCGATACTTGTAACGAAGGCTTTAGCTACGAATCACATCTCCACGCACATAAGCTACACGTTCATTCGCACGATTCGCCCGCTGACGAAGCGCGCGACCACGATACATCGGATCAGATACATCGCATATGTTCATGA
Protein Sequence
MARVLVYARPVDAIFMDIKLGSKTDPSEYAIRIKEEPIDPEICDDLSPVDTNTENENETAMCEGESSDGVYCRNRESAFPRESTYLENNKSDPDKRKSKHKVPSNNRISCNVCLLTFQTKHLLELHYKLYSCNVFKCNNCTAIFSMHIALIRHLKSRCRTKQWSGYRCNFCNRSFSYRRYIQSHLFHMHGNAILSGESKITKTSPESLGKSNHSDDIVMAESNTSHSSSPKSVNSSINISLKLSNSSNDTPTKGSGSKIKSTHPKWLNDSYGTPSKRMKQTVLTDFISLYKDKPNEKWVSPKEVIDTENIPVTATIIPTSTLETFSNKTSTASDVIQMSTSVKRIESPVRKRPFVQIHVNSKTMISLLRNEIGAESEGSNTSHNISYNLRPVKRCSSSLYNFYDLLEFEAFGRSRQSFKRNKSRYPFNQSERSASEAKCKECVVRLEKCDKFLEPTSFVSNGDKDEKEKENENEDGFKQAVSKNVKEKFEGFRETSSAGNLPLETGTIASKRFNEFVKSFVHRLIVPRQESVEFKKNSKVDQQKIFQCHICKKSFSLKENLREHVKLSHAIYMSSICNARYTSMNKLLTHYLRQHIVFKRRECCVCYEKFDTSALLKRHMILHCLKTIRSKKDVLPVDVEINCNAFKKQHKCQGCRKRFWLYSCLKQHENVCRRMKVSIHKQRVPRVNHLSRSLKEPSDMELGIVQSSDLEQTLDVPDGMTRPLENYLAPSTLITDDTNSSSFDTAAKNKRLLNGIACVKGYQADKMNGTKFPCTTCGTQFRTFQNLCIHERTYCQTATKKCNVCNTMFSTKRLLQLHMLATHTPSCSMNYKFFCKFCNQGFVKKSKVHIHERHFHIGENPRLGLNSDCVLKDKQICNICHLLFESYEHFVEHNTYYYKDKDFLCAVCGKSFKGMYKFHHHNKLEHYSDKLWKLYPYKCDTCNEGFSYESHLHAHKLHVHSHDSPADEARDHDTSDQIHRICS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00215949;
90% Identity
iTF_00222137;
80% Identity
-