Basic Information

Insect: Bombus vancouverensis
Gene Symbol: Baz2b
Assembly: GCA_011952275.1
Location: NW:195974-427647[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.5e-22 6.7e-19 66.6 0.0 4 76 605 677 602 678 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.5e-22	6.7e-19	66.6	0.0	4	76	605	677	602	678	0.94

Sequence Information

Coding Sequence: ATGGAGAAGGAGAACTCCGCATCGGGCGGAGGTGGCGGGGGCGGTGGAGGTGGCGGAGGTGAAGCGGCGGCCACGGCGACTCCAGGCGCCACCTCCGCCTCCGAGAAACTGCAGGCGGACCAGGCCAATCCGTTGCTCGATCCGACTGCGCTCTTCGGTGCGTATTGGCCTCGAGGCGACAGTGCAGCTTCGTCGTTATTCGGCGGAATGCCGGGCGGGTATGGATTGGGGGCCCATCATTTACCATCGGCTTATGCCATCTTGGGCCGTGGTGGCTCTGCTCCTGGATTCGGGGGGCACACACCAGCTTCCGCTCCACCACCACCTCCATACTCCCATAGCAGCCTTGGTACTCTGAGTGTAGCTGCCAGTCAGGCTGCGAGTTTAGGTATCAATCCTGCTAGTGCAGCGTGGTGGACAATGGCCTCACATTTAGCTGCACAGGACTACCTCGCGAGGTTACAAGGAGCGGCAGGGCTACCCGGATTTCCGCCTGGTGCCGAGAGCCTTCTGCCACCCTATCCTGCCTCTCTACTTAATCCCCCGTCCCTATCGTCACACAAGTCTAGTAAGTCTAAGTCAAGTAAGAGTCACAAGACGCCAGCGAGCAGTAGCAGCTCGACGACGCCGAGTATGACGGGCAGCAGTTTACCGGTTTCGACTCAAGCACCAGTCACGTCGTCTCATCACAGCACGTCGACCAGCAGCACGCCGAATTCGCAAACGAACGTTGTCAGTTCTGCGAAAGAGGGCAGcgATCCTAGCAGTATATTAGGAGGTGTACGCCTACCACCTGATACTGAGATTATCAAGTACACGTCGAGCATAGTCGGTCCAAAGGTTCCTGGCACAACGAACCGCGGGAGGAAGAAGACTatatccttagacacaccgAGTGTGAGTGTGCATCCACCGCCGGTACCTGCTCTGAGTGCTCATCAGACAAACACCACGACATCCTCGTTAATGATGGAACCGAGAAAATATAATCGCACGGGGACCGAGTCGAACGATTATAGGGAGTCGGTGGATCGCGTGGAGGTGATCAAACTGCCGGCGCACTCGACAAACGGCTCTGCCTTACCAGCGCCATCGTCGTATACAACAACCACTAACGCGAGCAATTCGAATGATTCGGACGCGCCGCTGAACCTCTCTCTGAAACCCTCGACGACGAGCAGTAGCTCGCCGATTTCAGGCAGTCAGCCGCTCAGTCAGCTCAGTAATTTAAGTCAGTCGTTACTCGCCTCCGATCGAACTTCGAGAAGAAAGCCAGGACCGAAGCCTCGAAGGGTGCCACAGAATTCCGTACCGGTGCCAGCATCGCCGAGTCCATCCTTGGCGCAGCTGTTCGCTGCAGCGGATTCACCTCAACGACCGAGCAGCGGAAGCGAGGAGAGCGAGAGCGCCAGCACAACCCACCACAAAGATGGTCGGCCGAGAAACTTGGGCCGTGGAGTATCTAAACCGAAGAAGAACACGGTGGCCTCGCTGCTAGCTCAGAGTAGAGCTTTGGGAATCAAACCGACGCCCACTTTGGATCCTAGTGTGCCATTGTCTCATCAGGTCTCGTTACTTAGGTCGAATATTCTGGCTGCTCAATTGCATGCCACTGCCACTGGCCAGGCCGATGACAAGAATCAGCGGTCTTTACAGGAGAAGATGAAGAACAAGGTGCTCGAGGTATCCGGTGAGGAGAGTAACATGGACGTGACGAGCGAGAGCGGCAGCAACACCGACGTTGTGACGGACACCGACGACGACAACGCGGATGGCGTGTCTAGCGcgaagagaagaaaagtgAAGCCTAGCGAGAGGGATCTCCAGGTGCCGCTTGAGCGTGGCTGGAAGCGAGAGACCGTCATCAAGGGATTAGGAAAGTCAGGGGTGATAAAGGGTGACGTGTCTTATTATAGTCCTTGTGGAAAGACGTTCAGGAGTAGTCCGGATTTGGCGAAGTTTTTGGAGCAACAGAATCCACCCGACTTAACGACGGCAAACTTTTCGTTCTCGTCTCGTCCGCTTGTGGGTGAATTCCTACAGCCAACGATGGGTCTCGCGGAGGCGGAATTCGTTAGGTTGGGCGCTCAGGAAGTTGCGAGAAGATTGGAGGAGTTGAGAGCCGCAGGTGGTTTCAGGGACGTGCGAACAAACAATCAGTACGAGAGGGAGAAACTGGCATATGCAAAAAAGCTAGCGAAAGAGGAGGCGCAACGACACAAGGAGCAAGCTAGGCTCATCAAGGAGCAAGAGAAAACGGAAAGGCAGGAGGCAGTGAGGCGAGAGCGGGAAATTCGAAATCAACAGCTGCTCGAGGGTCGAAAGCGGCTAGCGTTCACGATCAAGCAGAAAATGAAGATCATCCAAGAGATCGAACGCGGTAAGAGCAAGAGCGACGTGGCGCGCGAGCTGGGTCTGGCTAGCAGCACGGTGGCCACCATTTGGAAGAATCGGGAAAGCATCGCGGAGAGCTGGAGGAACCGCGACATGATGCAGCACTCTGATGTCGAGGACACGGTCGCAAAAAAGTCCGGCCTGTCCTCATCATCGTCGAATTTGGCGTCCGTCACGTCGTTGGTGACGAACAATACGGTGTTAAACACCGTCAACACCACCAACAGTAGCACCACCGGCACCACGTTGCCCACCGCCATCGTGGTGGCACCGCCACAGGTGCAGGTGGTGCCGCCGCCACCACCACCGCCTCTCCCATTGCCGACCACCTCCGCCACGGTCGTCCCGTCGACGTCGCAACCGACGCAGCTCTCCACACCGCCAATCTCCAGCACCATGTCCACAggcaccaccaccaccaccaacGCCAGCATGGACAATACTCAGCAGGCCCAGACCCAGACGCAAAGTCAGGAGCTTCTGGAGGACCCAGACGAAGGACCTCTCGAGGCTCGGAAAAAACGGCAGGAAGAGGTGGAGAAGATACGACTGGAAGAGCAACAACGGAAGCAACAGGAACGAGAACTGAAGCGGCAGCAGGCGGTTATGCTGAAAGAACAGATGTACATGCAGGAGCTCACCAAGCAGCGCGAGATGCTCTACACCGTCGAGCTGGAGAGAGAACGAAGGAGACAGCACATGGCGTTGGTTCGAGCGTTGGAAAATCGACGAAAAATggaggaaagagagaagaaacggTTAGAGGCGAGAGCCGAGAGAATAGCGACGAAGGAGAAACGAGCTGAACAGAGGAAGGTTGAGATGGAACTGATCGAACAGATCAGAAAGCCTGTCGAGGACATGGAGCTAACGGATCACAGACCACTGCCAGAATTGAAACGACTACCTGGTCTCAAGCTGTCCGGTCAGGCATTCGCAGACATTGTGATGGTGTTCGAATTTCTGCATAATTTCGGCGAGACTTTAGGCTTTGATATGGAATCGCTCCCAAGCCTAAAAAGCCTCCAACTCGCGCTGCTAAACGATGAGGAAGCTGAGGAAGAACTTCTTTCCGTGATGACACATCTGTTAGTATGCGCTATCGAAGATCCAGGAATCCCTCAACCGGCAAGGCATACAACCGGTCTTGGTCAAAGTTTACGTCAAGCTGATATAACGCACGCTAACATCAGCGAAGTCTTACGAATCTACTTATACGCGAACGCGACAGGAGAAGTGAAGGCTTTGACAGGAGTATGTTTGGAACGAGAGCGTGACAAGAAATTCGCAGATCATCATCAGAATGGCGGTGACTATGCCTCGACCTGTTCAGGAAAGAACGCTCAATTCTACGAACACTTGCACAACAACGAAACATGGAAGATGTCCGAGAGGCTGAGGGACAAACCGTTCCTGGCCTTGAATCCCACGCATAAGGCGCAGATGCTCGCGTTTCTCTGCAACGAGCTATTGCAGAACAAGGCTGTGATCCGACAGATCGAAGGTAGCTTGGAGACGGTAGCTCAATTGAGGAAAGAGAGATTTGTGTTGGATACAAAAATTAGGAAATTGAGGCAGTTGCATAGTCGAAAGGTTCGAATGGAAGCAGTTGGCGTAATCGTTAACAAAACTGGAGATACTATTACGATCGAGAAGAAAGAGGTTGACGAAGAAGGTAACACGACGTCGACAGCAGTAGGGACGACACCCACTCCTGATGAAATTCATCACGAAGACGAGGTTGAAGACATGTCCGAGAATGAGAGCGAAGGAACTCAGCCCGAGGAGGAGGAGGACAAAAATCTGTCCGGCGAAGAACTGGGTAAAAAATTGGATAAACTGTTGAAACAGTCAGAGGAACAATTGCAGAAATTGAACAGCTTCTCGAAACAGCTACGAGCACATATATTTGGGCAAGACAGATACTGGAGAAGATACTGGGAGCTGGCATGCGCTGGTGGCATCTTCGTCGAAGCCATGGAAAGCGCTGAACCAGAAATCCTAGAGTTGCAGGCTGAACTAGACGAAAAGTACAAAAACGTATCGATGGAGGAAAAATCAGAAACGAAGCAGGAGGACACCAAAGTCGAGAATCGCGAGAACGAAGCTCCTAACGACgtaaagaaggagaagaaattCAATTCGAGCGAGCAAGAGGCCGACGTCAAGCCTTTGGCGGACAAAACGAAATCTGAAAGTGAAGATGTTAATTGCAAGAAAGAACCTATGCAAAACTGCGAGAATTTGGCGAACatgaaggaagagaaaaagaatgaTTTGGATAATTCGATGACCGATGCGAAGACCAACGTCACGTCTGAAGAGATTAAACAAGAAACAGAGATAGTTAGTATGGATGTCGATATCAAAGAAGAGACGAAGAAGGAGAACGACGAAGCAGATGAAGACATGAAACCAGCGGTGAAGATAATGGAAGATAAAATCGTCGAAACAATTCCAAACGGTGATAAGTTCAACCATGTTAACAATCTTCATAATGGAAAAGAATTAAACGGCACCTTTATATCTAATAATAGCAACGAATCCAATTGGTTCTCGATTTTACCTCGCGAGACTTGCGATACTCCAGGACCAAGTACCAAGCAAATATTTGGAATAGCCGAACCAACCGAACTGAGAATACCAGTGTTCCCTCCGCCGGCTAGTCCAAATTATGACAGGTGCGACAGTCCAGCTCCTTTGATTTTGACTCAAGACGAAGCAGCGCAACTTGAGTATTTGAAAGTGCATGGTTTACCACCCCCTGGAGAAGCCAAACCAGTACCAAAAGATTTGAGATATGGTTGGTGGAGAATAACGGACGTAGACACGTTTCAAGAACTATTGGAGCACCTTCATTCTCGCGGTGTTCGCGAGAAGGAACTAAAACGTACAACGTGGGCGACCATGGAATCTTTCCTAGCTGTTACGGGCAAGATCAACGTGGACCCTGGTAACCTGACTGCTACCGAACTTCAAGCGACACCAGACGAACCCGACACACCGATTCCAAAACCAGACAACCCGGCTGACTGGAGTGAACAAGTCGCATTACGGGTAGATGCGCAGCTCTTGGAACAAGTCGAGGCTCTAGAAGATAAAGTCGCAAATGCCAGCATGCAGATCAAAGGCTGGAAGTTACCTCCACGAGCAGGAACCGAAGAGGcagaagaaattgaaaaactgAACGAAATGGAGAAAATTAGCGCGGTTGAACAAGCTCGACAAAGGTTACTGTCCCTGGAAGCAGCTATTGAAAGGAGATACTTAAAACCACCGTTAGGCGTTTGTACTGGAGATCCAAATCTAGCGGCCTTAAAGGCAGAACAAGCGGCCGCTGCTAACGCAAATTCGAATAATTCGGATCAGAGCAATCAGACCCCGATACCTCAAGAAGAAACAACTCCAAGAGGGCTGAACAACTGGCGAGAAGCAACGGCTCGAGCACACACGTCCGCTCAGCTCGCCATGGCGCTTTATATGTTGGAGGCCAGCATCGCTTGGGACAAGAGCATCATGAAGGCTGTGAGTCTAACACCAGCTAGAAACTCGGTCTGCGTCAAGCTACGAAACCGCTGCGTCTCACTCAAAGCTACCACTCAATACAATCAGCTATTGACTACTTCTCAGGCCTCTAATTGTCAGTTCTGTCATAGCGGAGATAACGAAGACAAACTATTACTGTGTGATGGTTGTGACCGCGGCTATCATACTTATTGTTTCCGTCCAAAAATGGAAAACATTCCTGATGGTGACTGGTATTGTCACGAATGCATGAACAAAGCTACAGGGGAACGAAACTGTTTGGTATGTGGAAAGAGGGTTGGTAAAAATTTAGTGCTATGTGAACTCTGTCCACGGGCTTATCACACTGACTGCCACAATCCTGTTATGCCAAAAATGCCAAGGGGTAAATGGTATTGTTCTAATTGCCACAGTAAACAACCAAAGAAGAGAAATAGTAGTCGAAGGAGTCATACCAAAGGGGCAGGCACCAGAGAAAGTGAAAGTTCTGATCATCCACCAGCTAGTCCAACGCCGTCAACGGCATCGAACACACACGTAGAGGACGTCAGTTCATCGGAACCGGCAACCCCAACTGCTTCGCCACGGAAGGAGGGAAACAATAGGACGCTCACGAAGAAACAGCAACGAGAGTTGGCTCCTTGTAAGGTGCTACTCGAACAGTTGGAGCAACAGGACGAGGCCTGGCCGTTCCTCTTGCCGGTGAACACCAAACAGTTTCCTACCtacaagaaaattattaaaacaccCATGGATCTCAGTACGATCAAGAAGAAATTGCAGGACTCCGTGTACAAGTCTCGCGATGAGTTTTGCGCCGATGTCAGACAGATGTTCATCAACTGCGAGGTATTCAACGAGGATGACAGTCCCGTGGGGAAGGCTGGACACGGGATGCGCAGTTTCTTCGAAATGCGTTGGACCGAGATTACTGGCGCACCACCTCCACACCCACAAACGCATAGCTGA
Protein Sequence: MEKENSASGGGGGGGGGGGGEAAATATPGATSASEKLQADQANPLLDPTALFGAYWPRGDSAASSLFGGMPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSTTPSMTGSSLPVSTQAPVTSSHHSTSTSSTPNSQTNVVSSAKEGSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPPVPALSAHQTNTTTSSLMMEPRKYNRTGTESNDYRESVDRVEVIKLPAHSTNGSALPAPSSYTTTTNASNSNDSDAPLNLSLKPSTTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHATATGQADDKNQRSLQEKMKNKVLEVSGEESNMDVTSESGSNTDVVTDTDDDNADGVSSAKRRKVKPSERDLQVPLERGWKRETVIKGLGKSGVIKGDVSYYSPCGKTFRSSPDLAKFLEQQNPPDLTTANFSFSSRPLVGEFLQPTMGLAEAEFVRLGAQEVARRLEELRAAGGFRDVRTNNQYEREKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRREREIRNQQLLEGRKRLAFTIKQKMKIIQEIERGKSKSDVARELGLASSTVATIWKNRESIAESWRNRDMMQHSDVEDTVAKKSGLSSSSSNLASVTSLVTNNTVLNTVNTTNSSTTGTTLPTAIVVAPPQVQVVPPPPPPPLPLPTTSATVVPSTSQPTQLSTPPISSTMSTGTTTTTNASMDNTQQAQTQTQSQELLEDPDEGPLEARKKRQEEVEKIRLEEQQRKQQERELKRQQAVMLKEQMYMQELTKQREMLYTVELERERRRQHMALVRALENRRKMEEREKKRLEARAERIATKEKRAEQRKVEMELIEQIRKPVEDMELTDHRPLPELKRLPGLKLSGQAFADIVMVFEFLHNFGETLGFDMESLPSLKSLQLALLNDEEAEEELLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEVLRIYLYANATGEVKALTGVCLERERDKKFADHHQNGGDYASTCSGKNAQFYEHLHNNETWKMSERLRDKPFLALNPTHKAQMLAFLCNELLQNKAVIRQIEGSLETVAQLRKERFVLDTKIRKLRQLHSRKVRMEAVGVIVNKTGDTITIEKKEVDEEGNTTSTAVGTTPTPDEIHHEDEVEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNSFSKQLRAHIFGQDRYWRRYWELACAGGIFVEAMESAEPEILELQAELDEKYKNVSMEEKSETKQEDTKVENRENEAPNDVKKEKKFNSSEQEADVKPLADKTKSESEDVNCKKEPMQNCENLANMKEEKKNDLDNSMTDAKTNVTSEEIKQETEIVSMDVDIKEETKKENDEADEDMKPAVKIMEDKIVETIPNGDKFNHVNNLHNGKELNGTFISNNSNESNWFSILPRETCDTPGPSTKQIFGIAEPTELRIPVFPPPASPNYDRCDSPAPLILTQDEAAQLEYLKVHGLPPPGEAKPVPKDLRYGWWRITDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGKINVDPGNLTATELQATPDEPDTPIPKPDNPADWSEQVALRVDAQLLEQVEALEDKVANASMQIKGWKLPPRAGTEEAEEIEKLNEMEKISAVEQARQRLLSLEAAIERRYLKPPLGVCTGDPNLAALKAEQAAAANANSNNSDQSNQTPIPQEETTPRGLNNWREATARAHTSAQLAMALYMLEASIAWDKSIMKAVSLTPARNSVCVKLRNRCVSLKATTQYNQLLTTSQASNCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRVGKNLVLCELCPRAYHTDCHNPVMPKMPRGKWYCSNCHSKQPKKRNSSRRSHTKGAGTRESESSDHPPASPTPSTASNTHVEDVSSSEPATPTASPRKEGNNRTLTKKQQRELAPCKVLLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKKLQDSVYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGAPPPHPQTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684165;
90% Identity: iTF_01068296;
80% Identity: iTF_00214391; iTF_00232603;