Bsup007507.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus superbus
Gene Symbol
SOX21
Assembly
GCA_014737385.1
Location
JACXIK010000019.1:4245293-4279789[+]

Transcription Factor Domain

TF Family
HMG
Domain
HMG_box domain
PFAM
PF00505
TF Group
Other Alpha-Helix Group
Description
High mobility group (HMG) box domains are involved in binding DNA, and may be involved in protein-protein interactions as well. The structure of the HMG-box domain consists of three helices in an irregular array. HMG-box domains are found in one or more copies in HMG-box proteins, which form a large, diverse family involved in the regulation of DNA-dependent processes such as transcription, replication, and strand repair, all of which require the bending and unwinding of chromatin. Many of these proteins are regulators of gene expression. HMG-box proteins are found in a variety of eukaryotic organisms, and can be broadly divided into two groups, based on sequence-dependent and sequence-independent DNA recognition; the former usually contain one HMG-box motif, while the latter can contain multiple HMG-box motifs. HMG-box domains can be found in single or multiple copies in the following protein classes: HMG1 and HMG2 non-histone components of chromatin; SRY (sex determining region Y protein) involved in differential gonadogenesis; the SOX family of transcription factors [1]; sequence-specific LEF1 (lymphoid enhancer binding factor 1) and TCF-1 (T-cell factor 1) involved in regulation of organogenesis and thymocyte differentiation [2]; structure-specific recognition protein SSRP involved in transcription and replication; MTF1 mitochondrial transcription factor; nucleolar transcription factors UBF 1/2 (upstream binding factor) involved in transcription by RNA polymerase I; Abf2 yeast ARS-binding factor [3]; yeast transcription factors lxr1, Rox1, Nhp6b and Spp41; mating type proteins (MAT) involved in the sexual reproduction of fungi [4]; and the YABBY plant-specific transcription factors.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 2 1e-30 5.3e-28 97.0 3.6 1 69 56 124 56 124 0.99
2 2 4.1 2.1e+03 -1.1 0.1 48 62 216 230 209 231 0.83

Sequence Information

Coding Sequence
ATGAGAGCCGGCGGCAACATGTGCGACGGCTCGTTCACTGAGACCCTGCGCGGTATGCAGGGCATGTCGGGTACGTCGCCACCCGGTGGAGCGGGGGTCGGCCCCATGGGGGTTGGCCTCGGTAGCCCTCTTGGACCGACCGCGAAGAAGGCGCAGGTGGAGCACATCAAGAGGCCGATGAACGCATTCATGGTATGGTCACGATTACAACGACGGAAGATCGCGCAGGAGAACCCGAAGATGCACAACTCGGAGATATCCAAGAGGCTCGGTGCCGAATGGAAGCTCTTGACCGAGGACGAGAAACGACCCTTTATCGATCAGGCGAAAAGGTTACGGGCACAGCACATGAAGGAACATCCCGACTACAAGTACAGACCTAGAAGAAAGCCGAAAACCTTACGAAAGGAAGGTTATCCTTACAGTATTCCGTATCCTAGTGTGCCGATGGATGCGCTCCGAGCTGGAATGGCTGGTGGAATGGGACAGGCAGGAATGGGATCGTATTATGGTCCCGCGGCCGCTTATGGTTCACTGTCTGCAGCCAGCATGGCCGCAGCCGCTGCTGCAGCAGCACAGCAGTCAGCAGCGGCGATGTCTGCGGGTCTAGCAGCACCTGCTCAGGTGGTGAGCTCGATGGACGCCATGAAGTACTCGATGGAGGCCGACAAATACCGGGCAGCATACATGCCGCCGAGCACTCTGGCGATGAGCATGTACTCCGACCCCAAGTATCTGGACTCGAGTCCAAAATCGTACCTGGACCGGAGCTACTTAGACTCCGCGAAGGCGTATTTCGAACAATCGAAGCTCTACATGGACCAGAAGCCTGCGATCACCGACTACAATCGGCCCAGTTACGAGCACAACAAGCTTTACGAAGAGTCCAGCCCCGGTAGTATCGTCGGTGGTGGTCCAACAAGGTCACCAGCCGCAGAATCTCCGGACATGAGCAAACAGCACGAGAGGACCGAGCAAGGTTCGTCTAGCGCGAGTTCTACGTCTACCTCGTCGGCTGCGAGTCCTGGTGCGAGTCTGCCAGCCTATTATCCAGGCTCGGTGCAAACCAGCGGTCTATTAGGACCCCAGATGAGCCAATACGGCGGCTATCAAACGGCTCCAGCGCCTGGAAACGAATCGTTCAGACGACCACTCACTGTCATCTTCTGA
Protein Sequence
MRAGGNMCDGSFTETLRGMQGMSGTSPPGGAGVGPMGVGLGSPLGPTAKKAQVEHIKRPMNAFMVWSRLQRRKIAQENPKMHNSEISKRLGAEWKLLTEDEKRPFIDQAKRLRAQHMKEHPDYKYRPRRKPKTLRKEGYPYSIPYPSVPMDALRAGMAGGMGQAGMGSYYGPAAAYGSLSAASMAAAAAAAAQQSAAAMSAGLAAPAQVVSSMDAMKYSMEADKYRAAYMPPSTLAMSMYSDPKYLDSSPKSYLDRSYLDSAKAYFEQSKLYMDQKPAITDYNRPSYEHNKLYEESSPGSIVGGGPTRSPAAESPDMSKQHERTEQGSSSASSTSTSSAASPGASLPAYYPGSVQTSGLLGPQMSQYGGYQTAPAPGNESFRRPLTVIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00086241; iTF_00088806; iTF_00087981; iTF_00085359; iTF_00087124; iTF_00084534; iTF_00730017; iTF_00730697; iTF_01228334; iTF_00264960; iTF_01514785; iTF_01512795; iTF_01454050; iTF_00016003; iTF_00016645; iTF_01048867; iTF_01048192; iTF_01068260; iTF_01068937; iTF_01066218; iTF_01067574; iTF_01066903; iTF_01070327; iTF_01069630; iTF_00881989; iTF_00882946; iTF_00879595; iTF_00881230; iTF_01390177; iTF_01393484; iTF_01389392; iTF_01394261; iTF_01391070; iTF_01391935; iTF_01120171; iTF_00200716; iTF_00011081; iTF_00460505; iTF_00089530; iTF_01392732; iTF_01077426; iTF_00880412; iTF_00221222; iTF_01089958; iTF_01498182; iTF_00015335; iTF_00866664; iTF_00231945; iTF_00225197; iTF_00214355; iTF_00141195; iTF_00965995; iTF_00982252; iTF_01070988; iTF_00773773; iTF_01411470; iTF_01413142; iTF_00939511; iTF_01303319; iTF_01414138; iTF_00938654; iTF_01412287; iTF_00060171; iTF_01200111; iTF_00174139; iTF_00174988; iTF_00175711; iTF_01539566; iTF_00219759; iTF_00221873; iTF_00360177; iTF_00417521; iTF_01406457; iTF_00181266; iTF_01261799; iTF_00181929; iTF_01476880; iTF_01476136; iTF_01477528; iTF_00754610; iTF_01123026; iTF_00117971; iTF_00228627; iTF_00233189; iTF_00760948; iTF_00633591; iTF_01255511; iTF_00232568; iTF_01087161; iTF_01523321; iTF_00014683; iTF_00718523; iTF_00862523; iTF_01122395; iTF_00963813; iTF_00159070; iTF_00452542; iTF_00142431; iTF_00684127; iTF_00684754; iTF_01015775; iTF_01355271; iTF_00229312; iTF_00863232;
90% Identity
iTF_00863232;
80% Identity
iTF_00228627;