Basic Information

Insect: Bombus sibiricus
Gene Symbol: Zfy1
Assembly: GCA_014737505.1
Location: JACXIM010000124.1:1287776-1296342[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 17 1.6 1.8e+02 3.3 0.3 1 23 79 104 79 104 0.95

2 17 0.25 28 5.8 1.3 2 23 117 138 117 139 0.93

3 17 4.7 5.2e+02 1.8 3.7 1 23 145 167 145 167 0.97

4 17 0.029 3.3 8.7 0.5 2 23 173 194 172 194 0.97

5 17 0.17 19 6.3 8.5 2 21 471 490 470 493 0.94

6 17 1.1 1.2e+02 3.8 0.3 1 23 558 580 558 580 0.82

7 17 1.1 1.2e+02 3.8 0.2 3 23 791 811 789 811 0.94

8 17 0.0044 0.49 11.3 0.3 1 23 819 841 819 841 0.98

9 17 0.14 16 6.6 1.1 2 23 937 958 936 958 0.95

10 17 0.47 52 4.9 1.2 3 23 970 990 969 990 0.96

11 17 0.0027 0.3 12.0 0.2 1 23 1067 1089 1067 1089 0.98

12 17 0.031 3.4 8.7 0.3 1 23 1163 1185 1163 1185 0.97

13 17 4.4e-05 0.0049 17.6 0.6 1 23 1191 1213 1191 1213 0.97

14 17 0.0045 0.51 11.3 2.6 1 23 1260 1282 1260 1282 0.97

15 17 0.00074 0.083 13.7 1.7 1 23 1288 1310 1288 1310 0.99

16 17 0.38 42 5.2 2.6 2 23 1402 1423 1401 1423 0.97

17 17 6.8 7.6e+02 1.3 0.3 2 23 1431 1452 1431 1452 0.79

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	17	1.6	1.8e+02	3.3	0.3	1	23	79	104	79	104	0.95
2	17	0.25	28	5.8	1.3	2	23	117	138	117	139	0.93
3	17	4.7	5.2e+02	1.8	3.7	1	23	145	167	145	167	0.97
4	17	0.029	3.3	8.7	0.5	2	23	173	194	172	194	0.97
5	17	0.17	19	6.3	8.5	2	21	471	490	470	493	0.94
6	17	1.1	1.2e+02	3.8	0.3	1	23	558	580	558	580	0.82
7	17	1.1	1.2e+02	3.8	0.2	3	23	791	811	789	811	0.94
8	17	0.0044	0.49	11.3	0.3	1	23	819	841	819	841	0.98
9	17	0.14	16	6.6	1.1	2	23	937	958	936	958	0.95
10	17	0.47	52	4.9	1.2	3	23	970	990	969	990	0.96
11	17	0.0027	0.3	12.0	0.2	1	23	1067	1089	1067	1089	0.98
12	17	0.031	3.4	8.7	0.3	1	23	1163	1185	1163	1185	0.97
13	17	4.4e-05	0.0049	17.6	0.6	1	23	1191	1213	1191	1213	0.97
14	17	0.0045	0.51	11.3	2.6	1	23	1260	1282	1260	1282	0.97
15	17	0.00074	0.083	13.7	1.7	1	23	1288	1310	1288	1310	0.99
16	17	0.38	42	5.2	2.6	2	23	1402	1423	1401	1423	0.97
17	17	6.8	7.6e+02	1.3	0.3	2	23	1431	1452	1431	1452	0.79

Sequence Information

Coding Sequence: ATGTCAGGAAGGCTACCCCGTCTGCGTGCACTTCGTCCACGACCCCAGCAATTTAAAACGGAGTCACATAAGGAAGGTAACCTTAAAGAGAACAGTCAGGGAGTCGTGATGAGGGAGCACGAGTTGCAAAGCGACACCGAAGACATTTCGTATAGTGTCAAAGATGATGTCCCAATAAAAAACAATTCAAAGCACGAACACGAGGAGCTCGATTGTTCGGGGTCTTCACAAAATTACGAATGTAAAACATGCAAACCACCAAAACCTCTATCAAGTCTTAAGGCGTATCTCGATCATCTGAAAAAGGAGCACAAACAAAAGGGGAAATTCATACGTGACACTGGAAATCGATGTTCTATGTGTTCATATGTTGCATTAAATTCAAGAGATCTTGAAACTCATCAGAGAGTACATCATTTAAAGAGAAGGTTTTTCCGATGTGCTAAGTGCTCTTATGTAACACATGTACGTGCTCGTTATACAAAGCATGTGAAATATCATTCCATGCCAATGATCAAATGTGATGCTTGTGATTTTCGTACGCCATATAAGTGGAATTTAGATAGGCACACTAGAAATCATGGAGGAGGAGGGGCTTTTCAATGTCGTGCTTGTAATTTTACAGCTGATATTAGACAAAGTTTAACAGTACATGAAACTAATCATCATGAACCTCCTGTGGGTCAAACAAATCGTAAATCTAGCACACCTTTTGAACGAAAACCAAGAAATAGTCCTAAACGTTACAATCAGGTGGGTGCAAGTGATTTTCGGGAATCACTACATATATCTACAGGTACAACAGTCTCAATCAGTCCTGGAGATTCATACATTTCTGATCAATCCATGGAAGATAAGAGAAGTGCAATAGCTAATGCAGAATGTATAGCATTGAAATGTGAAGAAAAAGGTTGCCAATTCATTACTGCATGGGATTCTGAGATGCAACGACACCTGGCAGAATGTCATGCTCCAATTACACCAAATAAATCCAGAAAACCACTGCCAATGTTAATTCCTCTAAGTCCTACTAAGCTAAATAGTATTAACTCCAGTGGACCTTCAACGACGTTGTTAAAAGTTCCACGTGTTAGAGTAAGACCGGAACTCGCGCAAATTGCAAGAGACACGGAACTGGCAAAATTATATGGAAATAAAGAAGTTAGCAACTTAAAGAAGGATGCGAATAACGCGGCCGATTTATTTGAAAAAAAAAATGCGTCGTTCTTTGATAAGCTTAAGGAAAAGCTTACAACGACAGCGTCAATTAATAATGGAGTACCGGAGGTAGCTGTAAGTACTACGAACGATTTGAAATGCTGGTGTACTTTTAAAGCTAGTAGCATGGAAGAGCTGGCTTGTCACAAACAAATACACCACACTGCTCTAAGTGTATCCGTGGGCACAACGCGTTGCCCGAAGTGCAGGAGACGTTGCAAAAGTTCGACTGATCTACAAGTGCATATGCAGTGTTGTCACTCGACAAGCAACGATACGTCAATACACAATAGCTTAGAAAAATTATCAAATTGTTCAGAACTCCGTGTGACCTCGTATCGCGGTGAATATGCATTCCCAGCGCAAACGGATTGGGACGTTAATCTCAGCGGACTGAATTCCTCTGGATCATCGGTTGAAGGTTCTTCGACGCATCCAAGTGGCCGATGGGTATACAAATGCCCGGATTGTCCCTTTTGGGCATCCACCGCAAGTCGTTTTCATGTTCATATTGTCGGTCATTTAAATCGGAAGCCATTCGAGTGTTCCCTATGCGCGTATCGCTCTAACTGGCGGTGGGACATCACAAAACATATTAAACTTAAAGCAGCTAAAGATCCAGTTCATATGACTGCCAGGGTACTTATGAGGGATGAAACAGGTCGACGGAATTATTCCAAATATAACAAATATCTTGCACAGGTCGAGCAACAGTCGTGGGATGATCAAAACATGGAGGAACGTAGCGTGGAAGAAACGAATTCTGACGAACCGCCAACTAAGTTATTCATAATGAATAGCAACGAATATCGGCAAACATCGGATCTCTCGTCTTCTCCTATTTCGATCGTGTCTCCGAATGAAGGAAACCATAATCTTAACACCATTAACGTCGGATTGAAACCACCACCGCTTCTTAAAGCTGCTGCGAGGAATCGGGGACAGTCTTTACTTAAAAGCAATTTGATTTCCTCTCATTCACTNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNTAAATCTCACAGTGAGCCAGCTGACCAACTCCATGGAGAAGAAAAAAATGTATTTGGTTGTGGAGATTGTCCATTTTCCGCATCTGATGCAGCAACGCTATCGATGCATAGAGTTCATCATCGTCCAAATTTGGATGCTATTTTTAAATGCTATTTATGTCCATATTATGTCAGCACAAAAGCAGAGCTTTTGGATCATGTCAGACTTCATGGAGAGGAGCTCGCCGTTGTGCACCAACAGAGTATGGAGTACAATTTTCCTACCAAGTCTAAAGCACATCGAACTTCAAACACTGATAATAGTATTAATCGCACGAAACAAGAAAAGTCTGTAGAGCAAGTGATTCATATCACAACGCAGAGCAACGTGACTTGTTTCACTAATGTTTCGAAGAATTCCGGAGCGCCACCGCCATTGCTTCTTGATACACGAGCACTGCCTGAAGCTCCATTAGTATGGGTGTCCCGACCAGATGGTACACTAGCGAAAATGTTAAAATGTCGTCACTGCCCTTTTGTATCTTCGCGACGAGCAGAAGTCCGAGATCATGAAACCATGCACCTCGATACTCCTAGTAATGGTCCTGTGGTCGCTTGCACAGATTGTAGTTTCACTTGCACACGGCGAGAAGTCATGGTTGCACACACAGATATGCATTCCGGATCTTTAGGCACTGTTCATTGTTTGGTAGATGATTCAAGGCCAGATTCGCAGCAATTAAGCGATTTGGCTGCGCTTCTCGGCTTTACTCATTCTCCGGTATTAGGTTCGGAACCTGATCTACGAGACTTAAGACTTGTGCATTGTTGTAGCAAATGTCCAGCGCGATTTCTTTGCGAAAAGGAATTAAGAATACATTTAAGATATCATTCTACAGAACTAGCTTATTCTTGCCAATGGTGTTCTTATGCTGCTCGACAACCGGCCCATCTTTTGGCCCATCAGAAGGCACATTCTACGGAGTATCAAGAGCGCACCAAATATTTGTTATCTTTATACGGCCAGTCACAGCGGTATCCGCCCCCTACCACAGCTTGTGTCGAAGCAAATAATCAAGATTCAAATAATTCTACACCTACCGTCGCATGGATTGTAGTCGAAGTTACAGAAAGTTCCAACAACGGGTTTAATAGTAGCATGAACAACACAAATCAACGAACTGGGAATCAAGTATTCACTTGTGCAAAATGTCCAGCTCGTTATTTCAAATTGGATGCTCTAGAATATCATATGACCTTACATGGGTCAAACAATAGATTTAAATGCACTGAGTGTGACTATTCGTCGAAGACGGCTCAGAATTTAGTGAAACATCAGGTAGTTCATAGACGTCAAAACGAAGCGAGCGATGTAACTTCAAATCTGTCGCCTCCTCCCGACCCACAGTTTGGACTTTTTATGCGTGGGAATCCTAACTTTGTATATCCTGGTTATTTAAGAAACGGCCGATTAAAAGAAAAGCGATATAAATGCCATAAATGTCCTTCTGCCTTTGAGAAACGAGAACAATACAGAGTTCATCTAACTCTGCACGGTGCGAAACAAAGATATCGCTGCGATACATGCGACTATTCCGTAAAATATTACGCTAATTATATTCAACATCTAAAGAAACATCAGGCAAATGCAGAGGCGCAAGCTTCACGTAGACAATTTGAGGACGATACAATTACCATTGATAGCGATAATATTTCCGATAATATAGGTTCCATTTCACGTTCAGGAAAGACGCTTAAATCACCCAATAATTCAGCTTCAATCATGACTACAAATGGTATACCAGTGTTAAATTTTGGTGGAGCACAGGCCTCGAATCAAGATAAGCAGTCGTTAATGTTGCTGCAAAAGAAAGGGATACTTCTATCTTCTAACGACGAAGTGGAGACGTTACGTTGTCAAAGCTGTCCGTTCTCTACGTGTGACAAAGACATGATGGATGCTCATAAGCGTCGACATGGCATTGAAAGAATGACACCGTCTTGTCCTCATTGCGATTATATACCGCGAAAAGATGAGAATGTCGGCGAACATATTAGATTGCATTTTACAAGACTTTATAAACCAGAATCCTATCTTATTATAGAATTATTAACATTGACAATGAAAAAGATATCTTCGAACGGAAAGGAAGAGAAACAAAAGGCTGCCGAATTACTTTTTAAAGAATACGCGGATGGAAGATTTTTTCCTTTTACCGATACCAATTCCTTTGGGAGTCCTCCTACTGTGAGCAGTTACAAAGAAAAAGTCATAGTCGATCCAAATACAGGAGAAACGAAACATTTAACTGTTTAG
Protein Sequence: MSGRLPRLRALRPRPQQFKTESHKEGNLKENSQGVVMREHELQSDTEDISYSVKDDVPIKNNSKHEHEELDCSGSSQNYECKTCKPPKPLSSLKAYLDHLKKEHKQKGKFIRDTGNRCSMCSYVALNSRDLETHQRVHHLKRRFFRCAKCSYVTHVRARYTKHVKYHSMPMIKCDACDFRTPYKWNLDRHTRNHGGGGAFQCRACNFTADIRQSLTVHETNHHEPPVGQTNRKSSTPFERKPRNSPKRYNQVGASDFRESLHISTGTTVSISPGDSYISDQSMEDKRSAIANAECIALKCEEKGCQFITAWDSEMQRHLAECHAPITPNKSRKPLPMLIPLSPTKLNSINSSGPSTTLLKVPRVRVRPELAQIARDTELAKLYGNKEVSNLKKDANNAADLFEKKNASFFDKLKEKLTTTASINNGVPEVAVSTTNDLKCWCTFKASSMEELACHKQIHHTALSVSVGTTRCPKCRRRCKSSTDLQVHMQCCHSTSNDTSIHNSLEKLSNCSELRVTSYRGEYAFPAQTDWDVNLSGLNSSGSSVEGSSTHPSGRWVYKCPDCPFWASTASRFHVHIVGHLNRKPFECSLCAYRSNWRWDITKHIKLKAAKDPVHMTARVLMRDETGRRNYSKYNKYLAQVEQQSWDDQNMEERSVEETNSDEPPTKLFIMNSNEYRQTSDLSSSPISIVSPNEGNHNLNTINVGLKPPPLLKAAARNRGQSLLKSNLISSHSLXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXKSHSEPADQLHGEEKNVFGCGDCPFSASDAATLSMHRVHHRPNLDAIFKCYLCPYYVSTKAELLDHVRLHGEELAVVHQQSMEYNFPTKSKAHRTSNTDNSINRTKQEKSVEQVIHITTQSNVTCFTNVSKNSGAPPPLLLDTRALPEAPLVWVSRPDGTLAKMLKCRHCPFVSSRRAEVRDHETMHLDTPSNGPVVACTDCSFTCTRREVMVAHTDMHSGSLGTVHCLVDDSRPDSQQLSDLAALLGFTHSPVLGSEPDLRDLRLVHCCSKCPARFLCEKELRIHLRYHSTELAYSCQWCSYAARQPAHLLAHQKAHSTEYQERTKYLLSLYGQSQRYPPPTTACVEANNQDSNNSTPTVAWIVVEVTESSNNGFNSSMNNTNQRTGNQVFTCAKCPARYFKLDALEYHMTLHGSNNRFKCTECDYSSKTAQNLVKHQVVHRRQNEASDVTSNLSPPPDPQFGLFMRGNPNFVYPGYLRNGRLKEKRYKCHKCPSAFEKREQYRVHLTLHGAKQRYRCDTCDYSVKYYANYIQHLKKHQANAEAQASRRQFEDDTITIDSDNISDNIGSISRSGKTLKSPNNSASIMTTNGIPVLNFGGAQASNQDKQSLMLLQKKGILLSSNDEVETLRCQSCPFSTCDKDMMDAHKRRHGIERMTPSCPHCDYIPRKDENVGEHIRLHFTRLYKPESYLIIELLTLTMKKISSNGKEEKQKAAELLFKEYADGRFFPFTDTNSFGSPPTVSSYKEKVIVDPNTGETKHLTV

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00762862;
90% Identity: iTF_00226234;
80% Identity: -