Basic Information

Gene Symbol
-
Assembly
GCA_014737505.1
Location
JACXIM010000120.1:299389-308715[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.00048 0.054 14.3 1.0 1 23 791 813 791 813 0.97
2 11 0.0014 0.15 12.9 0.1 2 23 904 925 903 925 0.96
3 11 0.044 5 8.2 0.3 3 23 1099 1119 1097 1119 0.95
4 11 0.0019 0.21 12.5 0.3 1 20 1203 1222 1203 1224 0.94
5 11 9.9 1.1e+03 0.8 1.2 2 23 1249 1272 1248 1272 0.70
6 11 0.056 6.3 7.8 0.2 1 23 1292 1314 1292 1314 0.97
7 11 2.9 3.3e+02 2.4 1.7 1 13 1321 1333 1321 1344 0.80
8 11 0.015 1.7 9.6 0.1 1 23 1363 1385 1363 1385 0.96
9 11 2.3 2.5e+02 2.8 0.8 1 19 1844 1862 1844 1864 0.85
10 11 1.4e-05 0.0016 19.1 0.7 1 23 2035 2057 2035 2058 0.96
11 11 0.21 23 6.1 0.6 1 23 2060 2082 2060 2082 0.95

Sequence Information

Coding Sequence
ATGAAAATTTCTAATGAATTATTTTCTTCACATCATTTGATTGATAATTACTCAGAGCAAGTAATTAACATGTCATTACCATTACCAAAGCCAAAACCTAAAGGTTCTAATGGAAAATACAAAAAAATCCAAGATACTAGTTGTTATATATTCAGGAAAAGATCAAGAAGTAATAGGTTGAAACAATTGTTAAGAAGAGGAGATACATTAGAGGATTTGTGTAAATTATTGTGTAAGCCAGTTATTGTGAATGTTACAAAATTATCAGTATCAGAGATAAAACAATGGTGTAAAAAAGACTTGCATCAATCTGAAGCAAAAAATATATTAACACAGAAAAAAAAATTTAAACGAAGGATACCACGAACAAGATTCTATAAAAGAAAGAAAAAGTCCAAACAGAAGCAGCAATTATCTTGCTTCTTATGTAATTCTGAAAATGAAGTTACACCTCAAAATATGTTATTTTCCAAGAAAGCAGAGATTGAAAACAAGAATTTTATAAAAAATTTATTAGAAGATGTTAAACAACCACATATAAAATTACAAAGAATAGATGAAGTAATCAATAAAATAGCACAGTCATTTGCAAGAGTAACTCCGATTAAAGAATGTGAAACAATTATTCAAACAGAATGTGGAACAAATATTCAATCTGAATGCGAAACAAATATTCCAACCAGATGTGAAACGAGTGTTCAAACAAGATGTGAGACAAGTATTCAAACAGAAGAAACTCAAACTGAATTAAGTATATCTGCATCAGAACAACTAAAATTATCATCTGTAAATATCGATACAGATAAATATCAACAAAATCTTGAAACTGAGACAATAGCAATTAGGTCTCATGCAAATGAGACTCTGCAATTGAATAAATGTGCAGATTCAGATTCAGATTCAGATTCAGATTCAGATTCTAATACTAATTCTGATTTTGATTCTAATGCTGGAAATTCTAGAAATACTAATGAAAGGAGACATAGAATTATATATAATTCTCATACAGATGATAACAATTGTTACAATAAGAGCAATGCAAATGCAAGAATAATTTCGAATAAATTAAAGAGGTTAAGGAGAAATTCACCAAAAAGAATAAGCAAAATTAACGTAGTAAATGAAAAATACAATATTATTAAGAAAAGATGTACAGGTAAAAATTCATTGTTTCAAACACCGCAAAGACNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNAAAGTACTAAAGAAGGTAATACTTCCAGTTGTGTGCCTTCAAAATTAAATCTTGAATGTATTATAGAAAATGGTACTTCTGTAAAAGGAAAGAATGAAGATGCTATGACTATAGAGAAACCAATTGTAGAAAACAAAAAGATTGAAGAACAAGTACAAGAATCATTTCTTTCCAATAGAAATTTTACACAAAGATATAAATTGTTTAAAGAATTAAAAGTTTTTTTAATAAAATTTGATGCTCTGAAAGACTCCAATACTACATATTCAGCAACTGAAATCGAGAAAATGACAGAAAGATTTACGAATTCTTACGTGAATTTAAATTCTTCAGAACTTCAAAATAGTAACAAAAAATCTATAAATAATGCATCATTTACTTCAGTCTTTTCAAAAGATTCTAATATTAACATTGAGAAATCTACAGATGCTACAAAACATGTTTCAAGCTCAAGTATTGATAGCATTTCAAATAAAGATGTTTATACAACTACCAAAAGAACACAAAGCACAGTTAAATTATTATCAAATTTTTCAGAAAAATTATCTCCAAATTCAATCAGAAACGCAAAGATACAACAAGAGAGGAGTTCACAAATTCAAAAAGTTTGTCATAATTTAACAAAAATTTTTGAAGACAGTTCTAAAAAAAGGTTTGCACAGAATACTATTAGTAATGCAAAGCAGAAATTGATTGTTCCAACCCCTACTGTCAAATCTACATTATTATATTCTTCACGAGAATCTACCAATAAAACTTCTGAATTATCAAATGTGGTAGAAAACATTGATAATATAGACAAATCTACTGGTAAAACGTTCTCCTTAAAGAAAAAGATACCAGAGATTTCTTCACGTAAGGAGAATTCTATAAAATTGGTTATTGATGCAAGATCTCAAGAACAAGTGGAAGTTGATACATCTGGTGTTACTAATTCCAAATTGCATCTTTCAAAGAAAAATAAAAAACATGAATTAGAGAAACACACATTTGCACCTAAAACGTGTGGGAAAACTATAAATGTTACAACTACTAAAATAGCTACAAAGAAAAGTGCTTCAACTTCTTATTCTTCCATAGTATCTCCTAAAAAACATAAAAGACTTAGAGATGATCTTGGTTATAAATGTATTGTTTGTGATCTTTGTTTTGAAGATTATTCTGATTTGCAACAACACCTAATTACACATACACAGAAGCAAAATAATAGTTTAGCAAATTCATTGAAAACTTCCAATATGTCACCTGAAAAATCTCAGGATATGATATCTCAATCCTCAAAAGCAAAGATATCAGAACCATCACAAGTGTCAAGTGAGCACAAGAGTGGAGAACATACAGCATCACAATATGTCACCAAGAAAGATAATGGACAACAAATGAAAAAAGATGCTATAACAAAAAGCTCACTGAGTAAAGAAAAGAGGAAAAGGAGGATTAAGCGTATTAGTAATTCAAATAAGTGTAGTATTTGTTCAAAACCTTTTGAAACAATGGCTGATTTGGCAGCTCATATCTTCTTACATACAGAGAGAGAATTGCAACAAGCATATAAATTCGCAAAACAAAAATTGAATGGAACAGAAAAATATAAACAAATTAGAACTGAACAAACAGCTAACAGTATTAAAAATGTAAATAGCACTGTAAATACTGCAGATAATATAATTGAAAGGACTCAGAAAGTTAATGATAAGGAAGAAACGTTGCTTATACAGAAACCAAATAAATCATTAATTACAGAAGATTCAGAAATTAGAGACACAGAATCTATTACTATGAAAGAAAACTATTCGCAAGATATAGAATTATGTCTTCCAGCAAAATCGAAAAAAGATGGTAATAAAAAATCGTTCACAGTATGCGAATGTCATAATAAACCAGGAACTAATGAAAATTGTTTGCAAATCGAAATAGTTCTTCTTTGTCACACTTGCAGGGTACTATTTAGAAGTATGAAATGTTTCGAAACCCATTATCGTCTTCCCGAATATATAAAATGTAATCAAAACCACTTAACTAGTGGTCGTTCTCCAAATTTATTTTGTGCTACCTGTGGTATGATATTTAGTTCAGTTCAAGATGTGCGTCATCATTTAGAAATACATGCTCGTTTTAAAAAAGACTGTACAATGGATTTTCGATGCAACATTTGCAAGGTTATATTCCTGGGAATAGGAAGCCTTTTTTATATCCATTGGTCAAAGCATTCCAGAGATTCTTTTTGGATGGCTAGTGAGAAATCGTTTCCAAAAGATTCCATAATAAACTCGAAGCTGAGAAAGGCAGAGAATTCTTCTACACAAAATGCAATGACTTTGAGTACGTGTGTAGAAAAATACATTGAAGTAGCAGAACATGTCTGTTATAATTGTAAACTGCCTTTTATTACTCAAGATGATTTAAAGAATCATATTTCAGAATGTAGAAAATTTAAGTCAGTTCAAGATGCATCTATTGCAGAAAACTCTAATACATATTTCGCAATAAGGATAACTTGTAGTTTATGCGATGATACTTTTATTAACAAAAAAACAGAATTTTATAAACATATGAAAGATAAACATAATTTGAGTACCGAACCTCGATTTATTTGTACATCATTTACGGCTGGAAATATGGTATTTATTTGCAATGTCTGCACAGCAATGACTAAAAGTTTAGATGACTTTGAGGATCATTGGTTGAAACATAATACAACTCATGTATATTTTACTTGTTCACATTGTAGTAAAATATATCACAACAGCTTAAATTCCTTCATAGACCATGCTAAAAGACATGGTATTGATGCTAATGATGTAGTGTCCTGTGTAGCAAATTATGAACAAACAAAATTCAGTTGTAAACTTTGTAACATTGGTTTTGATTCTCCTCAAAGTATGCAGGAGCATGCTATTATTCATAACACAAACAGCCAACAGATAAGTCCTAAGATTAGTCAAGTTACAAATCAAGACAGCTCTGCAACAGTATCAGAGACAGATTGTGCTTCCAATATTGCAAAGCTGGTTGAATTGACTCTTGAAAAGCAGATGGATGGATCATTACAAATGGAGACTCAAACAATGGAAAAGGCAAGCGAAATTTGTCCAATAGAATCTAGTATAGACAAAAGTAGGGATGAATTAATCAAAATATTAGAAGGAAATGAAGATGATTCTGAACATGAATTAATAATAGACTTGACAAAACAATCAGAAGAATGTAATGAAGGATTAAAAGAAGAAGGAAGTAAGGAAAGACAGACTACATCTAATGTTACATTAGATAAATCTTCTATCAATCAAACTAGTGTCATGTCGGAGAATAATAAAACTAATGCATTGGTAACAAATGTAAATGTCCAAGTATTTTCACAAAATGTTGCAAAATCTAAAACTCAAAATGTTACAGATTCTCTTTTTACTGCTAAAAACATAAATCCTCAAATATCTAATTCAAACATTAAGTCTACAGATATTTTGCAAACAATATTGGTTTCAAATAATGTTAGTAATAATAATAATCTACTAGATACAGAAAAAAAAACAACAAGTGACAAATCAATCACAAAAGATATAGAAAGTACACAAAATGTTGAAGTTCATGACAGAATTTCAATTATAAATCAAGAAGAATCAACAATTTTAACAAAAGAAACATCAGAGAAACAAGGTCCACCAAGACCAAGACAAGGGTTCTTAAGAGTGAAGACTCTTGCAGAGCTTACAGGTTCTACAAATTTATGTGAACTTAGCAATTGTGCTGTTGAAAATGCTAATGAATTAGCTAAGCACTTCAAAAGTCACCATGCTTCGAACAAAGATAATAATGAACACAAAACTACAGAAAAAGAATTAGTTTCAAAACAACCTGAAATAAACAAATTTATTGCCAATAAAAAATTAACAATTGTTCCTAATACAAATCCAAATACATTACTATTATCTTCATCTAATTCAGGCAATATAAAATTAGTGATTCAGAATCCAGTTATGAAATCTAATACTACAGTAATAAATAATCAACAACCACAGCAATTCCAAATAAATACAAATCAAAACGAACACTCATCTTCTCTGGAAAACGTAACATCAGCATATCATAAAAACTTACCAGCTTGCAATTTCGTTCGAACAACCACAGCTATGCCACGTTTTACTATTTTGAAACCTACCAAAGTAATAGCACATACTGCTAATATACCGAATGTACAGAAAACACATATTGCATCCTGTTCTACCAATGAAAATAAACAAAAGTCTTCTTCTGCAAAAAAAAATTCAAGTCATACTATACATAAGTGTAATCATTGCAATTTTGTTTCAAGTATTTCTGCAGAATTCTTAATGCACAATTTACCAGGTAATCGTTCAACTTGTAAGAAGCAATATTCGAAAAATGATACCCAGGCGCAAAAACTTAACAAATTTGATAATTCACAAACAATACCCACAATTAATACTATTCAAAACAATCCAAATCCCAAACGATGTCAACAAACTACTATGAAGCAACCAGGGATTAACTATGCGTCTTCATCTGTCTGTGATCAATATTCTTATCTTGCTGCAGGCACTTCGAATAATAGTAATCAAATGCTTAAACAAAATCAACCAATAATAACTAATCATCCAATAACAGGAAATACCACCCCTATTTATTATAAAAATCCAAATCCTAGCAGTGGTGGAATGTCAATAGTGATCAATCAAACTACACCTACTGTTCAGAATATACCCACAATAGGAATCCTGCAACAACCAGCGCAGCAACAAATATATCAACAACAGGATTTAGTTCAATTTTCCGAATCGAATGCTGTTTTCCAACTGGCAAATCAACCAAGTGTTACAACTTATCAAGTTAGATATGTATGTCCCTATTGTTCGAAAAGTTTTGTTTCTGAAGACTATATGCAAATACATATAAATGAGCACCACAATTTTATATGTAATATTTGTAATTTGCGTTTATACAGTTTTAACGATTTAAATCTTCATAAAATTCAGCATACTTTGTTGTAA
Protein Sequence
MKISNELFSSHHLIDNYSEQVINMSLPLPKPKPKGSNGKYKKIQDTSCYIFRKRSRSNRLKQLLRRGDTLEDLCKLLCKPVIVNVTKLSVSEIKQWCKKDLHQSEAKNILTQKKKFKRRIPRTRFYKRKKKSKQKQQLSCFLCNSENEVTPQNMLFSKKAEIENKNFIKNLLEDVKQPHIKLQRIDEVINKIAQSFARVTPIKECETIIQTECGTNIQSECETNIPTRCETSVQTRCETSIQTEETQTELSISASEQLKLSSVNIDTDKYQQNLETETIAIRSHANETLQLNKCADSDSDSDSDSDSNTNSDFDSNAGNSRNTNERRHRIIYNSHTDDNNCYNKSNANARIISNKLKRLRRNSPKRISKINVVNEKYNIIKKRCTGKNSLFQTPQRXXXXXXXXXXXXXXXXXXXXXSTKEGNTSSCVPSKLNLECIIENGTSVKGKNEDAMTIEKPIVENKKIEEQVQESFLSNRNFTQRYKLFKELKVFLIKFDALKDSNTTYSATEIEKMTERFTNSYVNLNSSELQNSNKKSINNASFTSVFSKDSNINIEKSTDATKHVSSSSIDSISNKDVYTTTKRTQSTVKLLSNFSEKLSPNSIRNAKIQQERSSQIQKVCHNLTKIFEDSSKKRFAQNTISNAKQKLIVPTPTVKSTLLYSSRESTNKTSELSNVVENIDNIDKSTGKTFSLKKKIPEISSRKENSIKLVIDARSQEQVEVDTSGVTNSKLHLSKKNKKHELEKHTFAPKTCGKTINVTTTKIATKKSASTSYSSIVSPKKHKRLRDDLGYKCIVCDLCFEDYSDLQQHLITHTQKQNNSLANSLKTSNMSPEKSQDMISQSSKAKISEPSQVSSEHKSGEHTASQYVTKKDNGQQMKKDAITKSSLSKEKRKRRIKRISNSNKCSICSKPFETMADLAAHIFLHTERELQQAYKFAKQKLNGTEKYKQIRTEQTANSIKNVNSTVNTADNIIERTQKVNDKEETLLIQKPNKSLITEDSEIRDTESITMKENYSQDIELCLPAKSKKDGNKKSFTVCECHNKPGTNENCLQIEIVLLCHTCRVLFRSMKCFETHYRLPEYIKCNQNHLTSGRSPNLFCATCGMIFSSVQDVRHHLEIHARFKKDCTMDFRCNICKVIFLGIGSLFYIHWSKHSRDSFWMASEKSFPKDSIINSKLRKAENSSTQNAMTLSTCVEKYIEVAEHVCYNCKLPFITQDDLKNHISECRKFKSVQDASIAENSNTYFAIRITCSLCDDTFINKKTEFYKHMKDKHNLSTEPRFICTSFTAGNMVFICNVCTAMTKSLDDFEDHWLKHNTTHVYFTCSHCSKIYHNSLNSFIDHAKRHGIDANDVVSCVANYEQTKFSCKLCNIGFDSPQSMQEHAIIHNTNSQQISPKISQVTNQDSSATVSETDCASNIAKLVELTLEKQMDGSLQMETQTMEKASEICPIESSIDKSRDELIKILEGNEDDSEHELIIDLTKQSEECNEGLKEEGSKERQTTSNVTLDKSSINQTSVMSENNKTNALVTNVNVQVFSQNVAKSKTQNVTDSLFTAKNINPQISNSNIKSTDILQTILVSNNVSNNNNLLDTEKKTTSDKSITKDIESTQNVEVHDRISIINQEESTILTKETSEKQGPPRPRQGFLRVKTLAELTGSTNLCELSNCAVENANELAKHFKSHHASNKDNNEHKTTEKELVSKQPEINKFIANKKLTIVPNTNPNTLLLSSSNSGNIKLVIQNPVMKSNTTVINNQQPQQFQINTNQNEHSSSLENVTSAYHKNLPACNFVRTTTAMPRFTILKPTKVIAHTANIPNVQKTHIASCSTNENKQKSSSAKKNSSHTIHKCNHCNFVSSISAEFLMHNLPGNRSTCKKQYSKNDTQAQKLNKFDNSQTIPTINTIQNNPNPKRCQQTTMKQPGINYASSSVCDQYSYLAAGTSNNSNQMLKQNQPIITNHPITGNTTPIYYKNPNPSSGGMSIVINQTTPTVQNIPTIGILQQPAQQQIYQQQDLVQFSESNAVFQLANQPSVTTYQVRYVCPYCSKSFVSEDYMQIHINEHHNFICNICNLRLYSFNDLNLHKIQHTLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00218063;
90% Identity
iTF_00226877;
80% Identity
-