Basic Information

Gene Symbol
-
Assembly
GCA_014737505.1
Location
JACXIM010000202.1:13969-20140[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.15 17 6.5 0.3 3 19 110 126 108 129 0.91
2 13 0.0054 0.6 11.0 1.0 1 22 135 156 135 156 0.95
3 13 0.011 1.2 10.1 6.2 1 23 166 189 166 189 0.93
4 13 2.1e-06 0.00023 21.8 3.1 1 23 540 563 540 563 0.97
5 13 1.7 1.9e+02 3.2 0.3 5 23 570 589 569 589 0.94
6 13 0.0016 0.18 12.7 1.0 2 23 596 617 596 617 0.96
7 13 0.93 1e+02 4.0 3.7 1 20 644 663 644 665 0.89
8 13 0.0033 0.37 11.7 2.1 1 22 766 787 766 787 0.96
9 13 0.0023 0.26 12.2 1.3 2 23 795 817 795 817 0.93
10 13 0.00082 0.092 13.6 4.5 1 23 827 850 827 850 0.95
11 13 3.4 3.9e+02 2.2 0.1 3 19 871 887 870 890 0.88
12 13 0.24 27 5.8 0.9 3 23 899 920 898 920 0.90
13 13 0.0049 0.55 11.2 4.2 1 23 931 954 931 954 0.95

Sequence Information

Coding Sequence
ATGTCTCGACTGTTAGTTTACGTACGCCCTGTTGATGCAATCTTCATGGATATAAAATTGGACAACAAAATGGACCTTTCTGAATGTGCAATAACAATAAAAGAAGAGTCAATCGATCCAGAGATCTGCGATGATTTGTCGTCAGTTGATACGAATAAAGGGAATGAAAATGAAACAGCAACGTTTAAAGGTGAATCTTTGGATGACGTTTATTGTAAAAATAAAGAATCCGCGTTTCCTCAAGAAAGTACGTATTTAGAAAATAACAAATCTGATCCTGATAAACGAAAAAGTAAACATAAAGTATCTTCAAACAACAGAATAATTTGCAATGTTTGTTTGTTAACTTTTCAAACTAAACATTTATTGGAACTGCATAATAAATTATATAGCTGTAATGTATTTAAGTGTAATAATTGCACTGCGATCTTCACTATGCATATTTCGTTGATACGCCATTTAAAGAAGCGATGTTGTACGAAAAAATTGTCTGGATATAGATGTAATTTTTGTAACCGAATATTTTCTTATAAAAGACATGTCCAATCTCATTTATTCCATGCGCATGGGAACGAAATATTTTCTAGCGAAAGCAAAATTACGAAAACGTCTCCTGAATCGTTAGGAAAGTCGAATCATTCGGATGGTATAGTCATGGCAGAATCAAATACTTCACACAGTCCCTCCCCAAAAAGCGTAAATAGCTCAATAAATATATCTTTGGAACTATCTAATAGTTCGAACAATACACTCACCGAGGGTTCGAGCAGCAAGATCAAGTCTACGCATTCGAAATGGTTAAATGATTTGCATGATACACCTTTGAAAAGGATGAAGCAGCCCGTCCTTACAGACTTCATATCGCTGTACAAAGACAAACCGAATGACAAATGTGTTAGCCCGGAAAAAGGTATCGATACGGAGAATATTCCTGTTACTGCGACTATTATTCCAACTTCAACGCTCGAAACATTTAGTAACAAGATATCAACGGCTGCAGAAGTTATTCAGATGTCTACTTCTGTTAAGCGAATCGAATCTCCTGTTAGGAAAAGCCCATTTGTTCAAATTCATGTGAATTTAAAAACAATGATATCTTCATTAAGGAACGAAATAAAAGCTGAATCTGAAAGCTCTAATACCTCGCACAATATGTCTTACAACCTTAGGCCAGTGAAAAGATGTTCTTCTTCTTTATATGATTTTTACGATTTATTGGACTTTGAGACCTTTGGAAGATCAAGACAATCTTTTAAAAGAAACAAGTTCCCCCATATATTTAACCAAAGTAGAAGATCTGCGCCTGAAGCTAAGTGTAAAGAATGTGTGGTCCGTTTGGAGAAATGCGACAAAATCTTCAAGCCTACTAGTTTTGTGTCAAACGAAGACGAAGACGAAAAAGGAGACGCTTTCAAACAAGCAGTATCGACAAATGCGAAAGAGAAATTTGGAGGTTTTCGTGAAACAAGCTCGGCAGGTAACTTGCCTTTGAAAGCTAACACGATTGCGTCAAAGCGATTCAATGAATTTGTAAAATCTTTCGCTGATAGATTAATCGTACTTCAACAAGAATCGGTTGAATTTCACAAGAACTTTAAGGTCAATCAGCAGAAAATATTTCAATGTCATATTTGTAAAAAATCATTTCCTTTGAAGGAGAACCTGCGCGAGCACATGAAATTGTTCCATACGATTTACATGTCGAGCATATGCAACGCGCGTTACACGTCCATGAATAAGTTACTATCTCACTATCTACGTCAGCATATTGTGTTTAAACGAAGGGAATGTTGCGTGTGTTATGAGAAGTTTGATACGTTGGCATTGTTGAAGCGGCACATGATTTTGCATTGTTTGAAGACCATAAGATCAAAAAAGAACGCTCCACCGGTTGATGTTGAAATAAATTGCAATGCATTCAAGAAACAACACAAATGCAAAGGTTGTCGCAAACGATTTTGGCTATACTCATGTTTGAAACAACATGAGAACGTATGTCGTCGAACGAAAGTCTTAATAAATAAACAACGTGTACCTTGTGTAAACCATTTGTCTCGGTCCTTGAAAGAACCAGGCGACATGGAACTCGGCATAGTACAGTCACCTGATTTGGAACAAATGTTGGATGTTTCGGGTGGGACGACAAGATCTTTGGAAAATTATTTGGCTCCGAGTACGCCTATTACGGATGATACTTTCTCTTCGTCATTCGATACAGCTGCAGAGAACAAAAGGTTACTTAATGGGATTGCATGCGTAAAGGGTCACCAAGCGGACAAGATGAACAGAACAAAATTTCCTTGCACTACTTGTGGAACACAATTCCAAACATTTAAAAATTTGTGCATACACGAGCGCACCTATTGCCAAACAGCCACAGAAAAGTGTAACGTTTGTAACACGATGTTTTCCACTAAAAGATTATTACAGTTTCACATGCTTGCTACTCATACGCCTTCGTGCTCGGTAAACTACAAATTCTTTTGTAAGTTCTGTAATCAAGGATTTGTTAAGAAATCGAATCTTCAAATTCACGAACGACACTTTCATATTGGGCAGGATTCTAGACTGGTGTTGAATTCCGATTGCGTTTTGAAAGATAAACCAATTTGTAATATATGCCATTTGTTATTCGAATCCTACGAACGTTTAGTCGAGCATAACATGTATTATTACAGGGGCAATGATATTTTATGCGCAATATGTGGTAAGGCGTTTCAAGGAATGTACAAGTTTCTTCATCACAACAAGTTGGAGCATTATCCGGACGAACCATGGAAATTGTACCCTTACAAATGCGATACTTGTAACGAAGGCTTCAACTACGAATCACATTTCCACGCACATAAGCTATACGTCCATTCGCACGATTCGCCCGCTGACGAGGCGCGCGACCGCGATACATCGGATCAGACTTTTCGCATGTGTTCATGA
Protein Sequence
MSRLLVYVRPVDAIFMDIKLDNKMDLSECAITIKEESIDPEICDDLSSVDTNKGNENETATFKGESLDDVYCKNKESAFPQESTYLENNKSDPDKRKSKHKVSSNNRIICNVCLLTFQTKHLLELHNKLYSCNVFKCNNCTAIFTMHISLIRHLKKRCCTKKLSGYRCNFCNRIFSYKRHVQSHLFHAHGNEIFSSESKITKTSPESLGKSNHSDGIVMAESNTSHSPSPKSVNSSINISLELSNSSNNTLTEGSSSKIKSTHSKWLNDLHDTPLKRMKQPVLTDFISLYKDKPNDKCVSPEKGIDTENIPVTATIIPTSTLETFSNKISTAAEVIQMSTSVKRIESPVRKSPFVQIHVNLKTMISSLRNEIKAESESSNTSHNMSYNLRPVKRCSSSLYDFYDLLDFETFGRSRQSFKRNKFPHIFNQSRRSAPEAKCKECVVRLEKCDKIFKPTSFVSNEDEDEKGDAFKQAVSTNAKEKFGGFRETSSAGNLPLKANTIASKRFNEFVKSFADRLIVLQQESVEFHKNFKVNQQKIFQCHICKKSFPLKENLREHMKLFHTIYMSSICNARYTSMNKLLSHYLRQHIVFKRRECCVCYEKFDTLALLKRHMILHCLKTIRSKKNAPPVDVEINCNAFKKQHKCKGCRKRFWLYSCLKQHENVCRRTKVLINKQRVPCVNHLSRSLKEPGDMELGIVQSPDLEQMLDVSGGTTRSLENYLAPSTPITDDTFSSSFDTAAENKRLLNGIACVKGHQADKMNRTKFPCTTCGTQFQTFKNLCIHERTYCQTATEKCNVCNTMFSTKRLLQFHMLATHTPSCSVNYKFFCKFCNQGFVKKSNLQIHERHFHIGQDSRLVLNSDCVLKDKPICNICHLLFESYERLVEHNMYYYRGNDILCAICGKAFQGMYKFLHHNKLEHYPDEPWKLYPYKCDTCNEGFNYESHFHAHKLYVHSHDSPADEARDRDTSDQTFRMCS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00225500;
90% Identity
-
80% Identity
-