Basic Information

Insect: Bombus sibiricus
Gene Symbol: BAZ2B
Assembly: GCA_014737505.1
Location: JACXIM010000076.1:192571-352943[-]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 2.2e-22 1.3e-18 66.7 0.0 4 76 599 671 596 672 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	2.2e-22	1.3e-18	66.7	0.0	4	76	599	671	596	672	0.94

Sequence Information

Coding Sequence: ATGGAGAAGGAGAACTCCGCATCGGGCGGAGGTGGCGGGGGCGGTGGAGGCGGCGGAGGTGAAGCGGCGGCCACGGCGACTCCAGGCGCCACCTCCGCCTCCGAGAAACTGCAGGCGGACCAGGCCAATCCGTTGCTCGATCCGACTGCGCTCTTCGGTGCGTATTGGCCTCGAGGTGATAGTGCAGCTTCGTCGCTATTTGGAGGAATGCCGGGCGGATATGGATTGGGGGCCCATCATTTACCATCGGCTTATGCCATCTTGGGCCGTGGTGGCTCTGCTCCCGGATTCGGGGGCCACACACCAGCTTCCGCTCCACCACCACCTCCATACTCCCATAGCAGCCTTGGTACTCTGAGTGTAGCTGCCAGTCAGGCTGCGAGTTTAGGTATCAATCCTGCTAGTGCAGCATGGTGGACAATGGCCTCACATTTAGCTGCACAGGACTACCTCGCGAGGTTACAAGGAGCGGCAGGGCTACCCGGATTTCCGCCTGGTGCCGAGAGCCTTCTGCCACCCTATCCTGCCTCTCTACTTAATCCCCCGTCCCTATCGTCCCATAAGTCTAGTAAGTCTAAGTCAAGCAAGAGTCACAAGACGCCAGCGAGCAGTAGCAGCTCGACGACGCCGAGTATGACGGGCAGCAGTTTACCGGTTTCGACTCAAGCACCAGTCACGTCGTCTCATCACAGCACGTCGACCAGCAGCACGCCGAATTCGCAAACGAACGTTGTCAGCGATCCTAGCAGTATATTAGGAGGTGTACGCCTGCCACCTGATACGGAGATTATCAAGTACACGTCGAGCATAGTCGGTCCAAAGGTTCCTGGCACAACGAACCGCGGGAGGAAGAAGACTATATCCTTAGACACACCGAGTGTGAGTGTGCATCCACCGCCGGTACCTGCTCTGAGTGCTCATCAAACAAACACTACGACATCTTCGTTAATGATGGAACCGAGAAAATATAATCGCACGGGGACCGAGTCGAACGATTATAGGGAGTCGGTGGATCGCGTGGAGGTGATCAAACTGCCGGCACACTCGACAAACGGCTCTGCCTTACCAGCTCCATCGTCGTATACAACAACCACTAACGCGAGCAATTCGAATGATTCGGACGCGCCGCTGAACCTCTCGCTGAAACCCTCGACGACGAGCAGTAGCTCGCCGATTTCAGGCAGTCAGCCGCTCAGTCAGCTCAGTAATTTAAGTCAGTCGTTACTCGCCTCCGATCGAACTTCGAGAAGAAAGCCAGGACCGAAGCCTCGAAGGGTACCACAAAATTCCGTACCGGTGCCAGCATCGCCGAGTCCATCCTTGGCGCAGCTGTTCGCTGCAGCGGATTCACCTCAACGACCGAGCAGCGGAAGCGAGGAGAGCGAGAGCGCCAGCACGACCCACCACAAAGATGGTCGACCGAGAAACTTGGGCCGTGGAGTATCTAAACCGAAGAAGAACACGGTGGCTTCGCTGCTAGCTCAGAGTAGAGCTTTGGGAATCAAACCGACGCCCACTTTGGATCCTAGTGTGCCATTGTCTCATCAGGTCTCGTTACTTAGGTCGAATATTCTGGCTGCTCAATTGCATGCCACTGCCACTGGCCAGACTGATGACAAGAATCAGCGGTCTTTACAGGAGAAGATGAAGAACAAGGTGCTCGAGGTATCCGGTGAGGAGAGTAACATGGATGTGACGAGCGAGAGCGGCAGCAACACCGACGTTGTGACGGACACCGACGACGACAACGCGGATGGCGTGTCTAGCGCGAAGAGAAGAAAAGTGAAGCCTAGCGAGAGGGATCTCCAGGTGCCGCTTGAGCGTGGCTGGAAGCGAGAGACCGTCATCAAGGGATTAGGAAAGTCAGGGGTGATAAAGGGTGACGTGTCTTATTATAGTCCTTGTGGAAAGACGTTCAGGAGTAGTCCGGATTTGGCGAAGTTTTTGGAGCAACAGAATCCACCCGACTTAACGACGGCAAACTTTTCGTTCTCGTCTCGTCCGCTTGTGGGTGAATTCCTGCAGCCAACGATGGGTCTCGCGGAGGCGGAATTCGTTAGGTTGGGCGCTCAGGAAGTTGCGAGAAGATTGGAGGAGTTGAGAGCCGCAGGTGGTTTCAGGGACGTGCGAACAAACAATCAGTACGAGAGGGAGAAACTGGCATATGCAAAAAAGCTAGCGAAAGAGGAGGCGCAACGACACAAGGAGCAGGCTAGGCTCATCAAGGAGCAAGAGAAAACGGAAAGGCAGGAAGCAGTGAGGCGAGAACGGGAGATTCGAAATCAACAGCTGCTCGAGGCTCGGAAAAAACGGCAGGAAGAGGTGGAGAAGATACGACTGGAAGAGCAACAACGGAAGCAACAGGAACGAGAACTGAAGCGGCAGCAGGCGGTTATGCTGAAAGAACAGATGTACATGCAGGAGCTCACCAAGCAGCGCGAGATGCTCTACACCGTCGAGCTGGAGAGAGAACGAAGGAGACAGCACATGGCGTTGGTTCGAGCGTTGGAAAATCGACGAAAAATGGAGGAAAGAGAGAAGAAACGGTTAGAGGCGAGAGCCGAGAGAATAGCGACGAAGGAGAAACGAGCTGAACAGAGGAAGGTTGAGATGGAACTGATCGAACAGATCAGAAAGCCTGTCGAGGACATGGAGCTAACGGATCACAGACCACTGCCAGAATTGAAACGACTACCTGGTCTCAAGCTGTCCGGTCAGGCGTTCGCTGACATCGTGATGGTGTTCGAATTTCTGCATAATTTCGGCGAGACTTTAGGCTTCGATATGGAATCGCTGCCAAGCCTAAAAAGCCTTCAACTTGCGCTGCTAAACGACGAGGAAGCTGAGGAAGAACTCCTTTCCGTGATGACACATCTGTTAGTATGCGCGATCGAGGATCCAGGAATCCCTCAACCAGCAAGGCACACAACCGGTCTTGGTCAAAGTTTACGTCAAGCTGATATAACGCACGCTAACATCAGCGAAGTCTTACGAATCTACTTGTACGCGAACGCTACAGGCGAAGTGAAGGCTTTGACAGGAGTATGTCTGGAACGAGAACGCGACAAGAAATTCGCAGATCATCATCAGAATGGCGGTGACTATGCCTCCACCTGTTCAGGCAAGAACGCCCAATTCTACGAACACTTGCACAACAACGAAACATGGAAGATGTCCGAGAGGCTGAGGGACAAACCGTTCCTGGCCTTGAATCCCACGCATAAGGCGCAGATGCTCGGGTTTCTCTGCAACGAGCTATTGCAGAACAAGGCTGTGATCAGACAGATCGAGGGTAGCTTGGAGACGGTAGCTCAATTGAGGAAAGAGAGATTTGTGTTGGATACAAAAATTAGGAAATTGAGGCAGTTGCATAGTCGAAAGGTTCGAATGGAAGCAGTTGGCGTAATCGTTAACAAAACTGGAGATACTATTACGATCGAGAAGAAAGAGGTTGACGAGGAAGGTAACACGACGTCGACAGCAGTGGGGACGACACCCACTCCTGATGAAATTCATCACGAAGACGAGGTTGAAGACATGTCCGAGAACGAGAGCGAAGGAACTCAGCCCGAGGAGGAGGAGGACAAAAATCTGTCCGGCGAAGAGCTGGGTAAAAAATTGGATAAACTGTTGAAACAGTCAGAAGAACAATTGCAGAAATTGAACAGCTCCTCGAAACAGCTACGAGCACATATATTTGGGCAAGACAGATGCTGGAGAAGATACTGGGAGCTGGCATGCGCTGGTGGCATCTTCGTCGAAGCTATGGAAAGCGCTGAACCAGAAATCCTAGAGTTGCAAGCTGAACTAGACGAAAAGTACAAAAACGTGTCGATGGAGGAAAAATCAGAAACGAAGCAGGAGGACACCAAAGTCGAGAATCGCGAGAACGAAGCTCCCAACGATGTAAAGAAGGAGAAGAAATTCAATTCGAGCGAGCAAGAGGCCGACGTCAAGCCTTTGGCGGATAAAACGAAATCTGAAATTGAAGATGTTAATTGCAAGAAAGAACCTATGCAAAACTGCGAGAATTTGGCGAACATGAAGGAAGAGAAAAAGAATGATTTGGATAGTTCGATGACCGATGCGAAGACCAACGTCACGTCTGAAGAGATTAAACAAGAAACAGAGATAGTTAGTATGGATGTCGATATCAAGGAAGAGACGAAGAAGGAGAACGACGAAGCAGATGAAGACACGAAACCAGCGGTGAAGATAATGGAAGATAAAATCGTCGAAACAATTCCAAACGGTGATAAGTTCAACCATGTTAACAATCTTCATAATGGAAAAGAATTAAACGGCACCTTTATATCTAATAATAGCAACGAATCCAATTGGTTCTCGATTTTACCTCGCGAGACTTGCGATACTCCAGGACCAAGTACCAAGCAAATATTTGGAATAGCCGAACCAACCGAACTGAGAATACCAGTGTTCCCTCCGCCGGCTAGTCCAAATTACGACAGGTGTGACAGTCCAGCTCCATTGATTTTGACTCAAGACGAAGCAGCGCAACTTGAGTATTTGAAAGTGCATGGTTTACCACCCCCTGGAGAAGCCAAACCAGTACCAAAAGATTTGAGATATGGTTGGTGGAGAATAACGGACGTAGACACGTTTCAAGAACTATTGGAGCACCTTCATTCTCGCGGTGTTCGCGAGAAGGAACTAAAACGTACAACGTGGGCGACCATGGAATCTTTCCTAGCTGTTACGGGCAAGATCAACGTGGACCCTGGTAACCTGACTGCTACCGAACTTCAAGCGACACCAGACGAACCTGACACACCGATTCCAAAACCAGACAACCCGGCTGACTGGAGCGAACAAGTCGCATTACGGGTAGATGCGCAACTCTTGGAACAAGTCGAGGCTCTAGAAGATAAAGTCGCAAATGCCAGCATGCAGATCAAAGGCTGGAAGTTACCTCCACGAGCAGGAACCGAAGAGGCAGAAGAAATTGAGAAACTGAACGAAATGGAGAAAATTAGCGCGGTTGAACAAGCTCGACAAAGGTTACTATCCCTGGAAGCGGCTATTGAAAGGAGATACTTGAAACCACCGTTAGGCGTTTGTACTGGAGATCCAAATCTAGCGGCCTTAAAGGCAGAACAAGCGGCCGCTGCGAACGCAAATTCGAATAATTCGGATCAGAGCAATCAGACCCCGATACCTCAAGAAGAAACAACTCCAAGAGGGCTGAACAACTGGCGAGAAGCAACGGCCCGAGCACACACGTCCGCTCAGCTCGCCATGGCGCTTTATATGTTGGAGGCCAGCATCGCATGGGACAAGAGCATCATGAAGGCTAATTGTCAGTTCTGTCATAGCGGAGATAACGAAGACAAACTATTACTGTGTGATGGTTGTGACCGCGGCTATCATACTTATTGTTTCCGTCCAAAAATGGAAAACATTCCTGATGGTGACTGGTATTGTCACGAATGCATGAACAAAGCTACAGGGGAACGAAACTGTTTGGTATGTGGAAAGAGGGTTGGTAAAAATTTAGTGCTATGTGAACTCTGTCCACGGGCTTATCACACTGACTGCCACAATCCTGTTATGCCAAAAATGCCAAGGGGTAAATGGTATTGTTCTAATTGCCACAGTAAACAACCAAAGAAGAGAAATAGTAGTCGAAGGAGTCATACCAAAGGGGCAGGCACCAGAGAAAGTGAAAGTTCTGATCATCCACCAGCTAGTCCAACGCCGTCAACGGCATCGAACACACACGTAGAGGACGTCAGTTCATCGGAACCGGCAACCCCAACTGCTTCGCCACGGAAGGAGGGAAACAATAGGACGCTCACGAAGAAACAGCAACGAGAGTTGGCTCCTTGTAAGGTGCTACTCGAACAGTTGGAGCAACAGGACGAGGCCTGGCCGTTCCTCTTGCCGGTGAACACCAAACAGTTTCCTACCTACAAGAAAATTATTAAAACACCCATGGATCTCAGTACGATCAAGAAGAAATTGCAGGACTCCGTGTACAAGTCTCGCGATGAGTTTTGCGCCGATGTCAGACAGATGTTCATCAACTGCGAGGTATTCAACGAGGATGACAGTCCCGTGGGGAAGGCTGGACACGGGATGCGCAGTTTCTTCGAAATGCGTTGGACCGAGATTACTGGCGCACCACCTCCACACCCACAAACGCATAGCTGA
Protein Sequence: MEKENSASGGGGGGGGGGGGEAAATATPGATSASEKLQADQANPLLDPTALFGAYWPRGDSAASSLFGGMPGGYGLGAHHLPSAYAILGRGGSAPGFGGHTPASAPPPPPYSHSSLGTLSVAASQAASLGINPASAAWWTMASHLAAQDYLARLQGAAGLPGFPPGAESLLPPYPASLLNPPSLSSHKSSKSKSSKSHKTPASSSSSTTPSMTGSSLPVSTQAPVTSSHHSTSTSSTPNSQTNVVSDPSSILGGVRLPPDTEIIKYTSSIVGPKVPGTTNRGRKKTISLDTPSVSVHPPPVPALSAHQTNTTTSSLMMEPRKYNRTGTESNDYRESVDRVEVIKLPAHSTNGSALPAPSSYTTTTNASNSNDSDAPLNLSLKPSTTSSSSPISGSQPLSQLSNLSQSLLASDRTSRRKPGPKPRRVPQNSVPVPASPSPSLAQLFAAADSPQRPSSGSEESESASTTHHKDGRPRNLGRGVSKPKKNTVASLLAQSRALGIKPTPTLDPSVPLSHQVSLLRSNILAAQLHATATGQTDDKNQRSLQEKMKNKVLEVSGEESNMDVTSESGSNTDVVTDTDDDNADGVSSAKRRKVKPSERDLQVPLERGWKRETVIKGLGKSGVIKGDVSYYSPCGKTFRSSPDLAKFLEQQNPPDLTTANFSFSSRPLVGEFLQPTMGLAEAEFVRLGAQEVARRLEELRAAGGFRDVRTNNQYEREKLAYAKKLAKEEAQRHKEQARLIKEQEKTERQEAVRREREIRNQQLLEARKKRQEEVEKIRLEEQQRKQQERELKRQQAVMLKEQMYMQELTKQREMLYTVELERERRRQHMALVRALENRRKMEEREKKRLEARAERIATKEKRAEQRKVEMELIEQIRKPVEDMELTDHRPLPELKRLPGLKLSGQAFADIVMVFEFLHNFGETLGFDMESLPSLKSLQLALLNDEEAEEELLSVMTHLLVCAIEDPGIPQPARHTTGLGQSLRQADITHANISEVLRIYLYANATGEVKALTGVCLERERDKKFADHHQNGGDYASTCSGKNAQFYEHLHNNETWKMSERLRDKPFLALNPTHKAQMLGFLCNELLQNKAVIRQIEGSLETVAQLRKERFVLDTKIRKLRQLHSRKVRMEAVGVIVNKTGDTITIEKKEVDEEGNTTSTAVGTTPTPDEIHHEDEVEDMSENESEGTQPEEEEDKNLSGEELGKKLDKLLKQSEEQLQKLNSSSKQLRAHIFGQDRCWRRYWELACAGGIFVEAMESAEPEILELQAELDEKYKNVSMEEKSETKQEDTKVENRENEAPNDVKKEKKFNSSEQEADVKPLADKTKSEIEDVNCKKEPMQNCENLANMKEEKKNDLDSSMTDAKTNVTSEEIKQETEIVSMDVDIKEETKKENDEADEDTKPAVKIMEDKIVETIPNGDKFNHVNNLHNGKELNGTFISNNSNESNWFSILPRETCDTPGPSTKQIFGIAEPTELRIPVFPPPASPNYDRCDSPAPLILTQDEAAQLEYLKVHGLPPPGEAKPVPKDLRYGWWRITDVDTFQELLEHLHSRGVREKELKRTTWATMESFLAVTGKINVDPGNLTATELQATPDEPDTPIPKPDNPADWSEQVALRVDAQLLEQVEALEDKVANASMQIKGWKLPPRAGTEEAEEIEKLNEMEKISAVEQARQRLLSLEAAIERRYLKPPLGVCTGDPNLAALKAEQAAAANANSNNSDQSNQTPIPQEETTPRGLNNWREATARAHTSAQLAMALYMLEASIAWDKSIMKANCQFCHSGDNEDKLLLCDGCDRGYHTYCFRPKMENIPDGDWYCHECMNKATGERNCLVCGKRVGKNLVLCELCPRAYHTDCHNPVMPKMPRGKWYCSNCHSKQPKKRNSSRRSHTKGAGTRESESSDHPPASPTPSTASNTHVEDVSSSEPATPTASPRKEGNNRTLTKKQQRELAPCKVLLEQLEQQDEAWPFLLPVNTKQFPTYKKIIKTPMDLSTIKKKLQDSVYKSRDEFCADVRQMFINCEVFNEDDSPVGKAGHGMRSFFEMRWTEITGAPPPHPQTHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00684165;
90% Identity: iTF_00684165; iTF_00224551; iTF_01514823; iTF_01514155; iTF_00215020; iTF_00760979; iTF_00219797; iTF_00221909; iTF_00141824;
80% Identity: -