Blap014362.2


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus lapidarius
Gene Symbol
-
Assembly
GCA_936014575.1
Location
CAKXZU010000089.1:454377-460906[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.00055 0.038 14.3 1.0 1 23 787 809 787 809 0.97
2 10 0.034 2.4 8.7 0.0 2 23 900 921 899 921 0.95
3 10 0.05 3.5 8.1 0.3 3 23 1095 1115 1093 1115 0.95
4 10 0.0021 0.15 12.5 0.3 1 20 1199 1218 1199 1220 0.94
5 10 0.096 6.7 7.3 0.2 1 23 1288 1310 1288 1310 0.97
6 10 3.3 2.3e+02 2.4 1.7 1 13 1317 1329 1317 1340 0.80
7 10 0.017 1.2 9.6 0.1 1 23 1359 1381 1359 1381 0.96
8 10 0.18 12 6.4 1.7 1 19 1840 1858 1840 1860 0.95
9 10 2e-05 0.0014 18.8 0.7 1 23 2048 2070 2048 2071 0.96
10 10 0.23 16 6.0 0.6 1 23 2073 2095 2073 2095 0.95

Sequence Information

Coding Sequence
ATGGAAATTTCTAATGAAGAATTATTTTCTCCACATCATTTGATTGATAATTACTCAGAGCAAATAATTAACATGTCATTACCATTACCAAAGCCAAAACCTAAAGGTTCTAATGCAAAATACAAAAAAATCCAAGATACTAGTTGTTATATATTGAGGAAAAGATTAAGAAGTAATAGGTTGAAACAATTGTTAAGAAGAGGAGATACATTAGAGGATCTGTGTAAATTATTGTGTAAGCCAGTTATTGTGAATGTTACAAAATTATCAGTATCAGAGATAAAACAATGGTGTAAAAAAGACTTGCATCAATCTCAAGCAAAAAACATATTAACACAGAAAAAAAAATTTAAACGAAGAATACCACGAACAAGATTCTATAAAAGAAAGAAAAAGTCCAAACAGAAGCAGTTATCTTGCTTATGTAATTCTGAAAATGAAGTTACACCTCAAAATATGTTATTTTCCAAGGAAGCAGAGATTGAAAACAAGAATTTTATAAAAAATTTATTAGAAGATGTTAAACAACCACATATAAAATTACAAAGAATAGATGAAGTAATCAATAAAATAGCACAGTCATTTGCAAGAGTAACTCCGATTAAAGAATGTGAAACAATTATTCAAACAGAATGTGGAACAAATATTCAATCTGAATGTGAAACAAATATTCCAACCAGATGTGAAACAAGTGTTCAAACAAGATGTGAGACAAGTATTCAAACAGAAGAAACTCAAACTGAATTAAGTATATCTGCATCAGAACAACTAAAATTATCATCTGTAAATATCGATACAAATAAATATCAACAAAATCTTAAAACTGAGACAGTAGCAATTAGGTCTCATGCAAATGAGACTCTACAATTGAATAAATGTGCAGATTTAGATTCAGATTCAGATTCTAATACTATTTTTGATTTTGATTCTAATACTGGAAATTCTAGAAATACTAATGAAAGGAGACATAGAATTATATATAATTCTCATACAGATGATAACAATCGTTACAATAAGGGCAATGCAAATAATGCAAGAATAATTTCGAATAAATTAAAGAGGTTAAGGAGAAATTCATCAAAAAAAATAAACAAAATTAACCTAGTAAATGAAAAATACAATATTATTAAGAAAAGATGTACAGGTAAAAATTCATTGTTTCAAGCACCACAAAGACCAAGTATATTAGACCGTATATCTGCGCTATGTGATCCTGATGATGATGATGATGATGATGATGAAAGTACTAAAGAAGGTAATACTTCCAATTGTGTGCCTTCAAAATTAAATCTTGAATGTATTATAGAAAATGATACTTCTATAAAAGGAAAAAATGAAGATGCTATGACTATAGAGAAACCAATTGTAGAAAACAAAAAGATTGAAGGACAAGTACAAGAATCATTTCCTTCCGATAGAAATTTTACACAAAGGTATAAATTGTCTAAAGAATTAAAAGTTTTTTTAATAAAATTTGATGCTCTGAAAGACTCCAATACTACATATTCAGCAACTGAAATCGAGAAAATGACAGAAAGATTTACGAATTCTTACGTGAATTTAAATTCTTCAGAACTTCAAAATAGTAACGAAAAATCTATAAATAATGCATCATTTACTTCAATCTTTTCAAAAGATTCTAATGTTAACATTGAGAAATCTACAGATGCTGCAAAACATGTTTCAAGCTCAAGTATTGATAGCATTACAAATAAAGATGTTTATACAACTACCAAAAGAACACAAAGCACAATTAAATTATTATCAAATTTTTCAGAAAAATTATCTCAAAATTCAATTAGAAATGCAAAGATACAACAAGAGAGGAGTTCACAAATTCAAAAAGTTTGTCATAATTTAACAAAAATTTTTGAAGACAGTTCTGAAAAAAGGTTTGCACAGAATACTATTAGTAATGCAAAGCAGAAATTGATTGTTCCAACCTCTACTATCAAATCTACATTATTATATTCTTCACAAGAATCTACCAATAAACCTTCTGAATTATCAAATGTGGTAGAAAACATTGATAATATAGACAAATCTACTGGTAAAACGTTCTCCTTAAAGAAAAAGATACCAGAGATTTCTTCACGTAAGAAGAATTCTATGAAATTGGTTATTGATGCAAGATCTCAAGAACAAATGGGAGTTGATACATCTGATGTTACTAATACCAAATTGCATCTTTCAAAGAAAAATAAAAAACATGAGTCAGAGAAACGTACATTTGCACCTAAAACATGTGGGAAAACTATAAATGTTACAACTACTAAAACAGCTACAAAGAAAAGTGCTTCAACTTCTTATTCTTCCACAGTATCTCCTAAAAAATATAAAAGACTTAGAGATGATGGTTATAAATGTATTGTTTGTGATCTTTGTTTTGAAGATTATTCCGATTTACAACAACACCTAATTACACATACACAAAAGCAAAATAATAGTTTAGCAAATTCATTGAAAACTTCCAATATGTCACCTGAAAAATCTCAGGACATGATATCTCAATTCTCAAAAGCAAAGATATCAGAACCATCACAAGTGTCAAGTGAGCACAAGAGTGGAGAACATACAGCATCACAATATGTCACCAAGAAAGATAATGGACAACAAAAGAAAAAAGATGCTATAACAAAAAGTTCACTGAGCAAAGAAAAGAGGAAAAGGAGGATTAAGCGTATTAGTAATTCAAATAAGTGTAGTATTTGTTCAAAACCTTTTGAAGCAATGGCTGATTTGGCAGCTCATATCTTTTTACATACAGAGACAGAATTGCAACAAGCATATAAACTCGCAAAACAAAAATTGAATGGAACAGAAAAATATAAACAAACTAGAACTGAACAAACAGCTAACAGTATTAAAAATGTAAATAGCACTGTAAATACTGCAGATAATATAATTGAAAGGACTCAGAAAGTTAATGATAAGGAAGAAACATTGCTTATACAGAAACCAAATAAATCATTAATTACAGAAGATTCAGAAATTAGAGATGCAGAATCTATTACTATGAAAGAAAACTATTCGCAAGATATAGAATTATGTCTGCCAGCAAAATCGAAAAAAGATGGTAATAAAAAATCGTTCACAGTATGCGAATGTCATAATAAACCAGGAACTAATGAAAATTGTTTGCAAATCGAAATAGTTCTTCTTTGTCACACTTGCAGAGTGCTATTTAGAAGTATGAAATGTTTCGAAACCCATTATCGTCTTCCCGAATATATAAAATGTAATCAAAACCACTTAACTAGTGGTCGTTCTCCAAATTTATTTTGTGCTACCTGTGGTATGATATTTAGTTCAGTTCAAGATGTGCGTCATCATTTAGAAATACATGCTCGTTTTAAAAAAGACTGTACAATGGATTTTCGATGTAACATTTGCAAGGTTATATTCCTGGGAATAGGAAGCCTTTTTTATATCCATTGGTCAAAGCATTCCAGAGATTCTTTTTGGATGGCTAGTGAGAAATCGTTTCCAAAAGATTCCATAATAAACTCGAAGCTGAGAAAGGCAGAGAATTCTTCTACACAAAATGCAATGACTTTGAGTACGTGTGTAGAAAAATACATTGAAGTAGCAGAACATGTCTGTTATAATTGTAAATTGCCTTTTATTACTCAAGATGATTTAAAAAATCATATTTCAGAATGTAGAAAATTTAAGTCAGTTCAAGATTCATCTATTGCAGAAAACTCTAATACATATCTCGCAATAAGGATAACTTGTAGTTTATGCGATGATACTTTTATTAACAAAAAAACAGAATTTTATAAACATATGAAAGATAAACATAATTTGAGTACCGAACCTCGATTTATTTGTACATCATTCACGGCTGGAAATATGGTATTTATTTGCAGTGTCTGCACGGCAATGACTAAAAGTTTAGATGACTTTGAGGATCATTGGTTGAAACATAATACAACTCATGTATATTTTACTTGTTCGCATTGTAGTAAAATATATCACAATAGCTTAAATTCCTTCATAGACCATGCTAAAAGACATGGTATTGATGCTAATGATGTAGTGTCCTGTGTAGTAAATTATGAACAAACAAAATTCAGTTGTAAACTTTGTAATATTGGTTTTGATTCTCCTCAAAGTATGCAGGAGCATGCTATTATCCATAACACAAACAGCCAACAGATAAGTCCTAAGATTAGGCAAGTTACAAATCAAGACAGCTCTGCAACAGTATCAGAGACAGATTGTGCTTCCAATATTGCAAAGCTGGTTGAATTGACTCTTCAAAAGCAGAAGATGGATGGATCATTACAAATGGAGACACAAACAATGGAAAAGGCAAGCGAAATTTGTCCAATAGAATCTAGTATAGACAAAAGTAGGGATGAATTAATCAAAATATTAGAAGGAAATGAAGATGATTCTGAACATGAATTAATAATAGACTTGACAAAACAATCAGAAGAATGTAATGAAGGATTAAAAGAAGAAGGAAGTAAGGAAAGACAGACTACATCTAATCTTACATTAGATAAATCTTCTATCAATCAAACTTGTGTCATGTCGGAGAATAATAAAGCTAATGCATTGGTAACAAATGTAAATGTCCAAGTATCTTCACAAAATGTTGCAAAATCTAAAACTCAAAATGTTACAGATTCTCTTTTTACTGCTAAAAGCATAAATCCTCAAATATCTAATTCAAACATTAAGTCTACAAATATTTCGCAAACAATATTGGTTTCAAATAATGTTAGTAATCATAATAATCTACTAGATATAGAAAAAAAAATAAGTGACCAATCAATCACAGAAGATATAGAAAGTACACAAAATGTTGAAGTTCATGACAGAATTTCAATTATAAATCAAGAAGAATCAACAATTTTAACAAAAGAAACATCAGAGAAACAAAGTCCACCAAGACCAAGAAAAGGATTCTTAAGAGTGAAGACTCTTGCAGAGCTTACAGGTTCTACAAATTTATGTGAACTTAGCAATTGTGCTGTTGAAAATGGTAATGAGTTAGCCAAACACTTCAAAAGTCACCATGCTTCGAACAAAGATAATAATGAACACAAAACTACAGAAAAAGAATTAGTTTCAAAACAACCTGAAATAAACAAATTTATTGCCAATAAAAAATTAACGATTGTTCCTAATACAAATTCAAATACATTACTATTATCTTCATCTAATTCAGGCAATATAAAATTAGTGATTCAGAATCCAGTTATGAAATCTAATACTACAATAATAAATAATCAACAACCACAGCAATTCCAAATAGATACAAATCAAAAAGAACACTCATCTTCTCTGGAAAATGTAACATCAGCATATCATAAAAACTTACCAGCTTGCAATTTCGTTCGAACAACCACAGCTATGCCACGTTTTACTATTTTGAAACCTACCAAAGTTATAGCACACACTGCTAATATACCGAATGTACAGAGAACACATGTAGCATCCTGTTCTACCAATGAAAATAAACAAAAGTCTTCTTCTGCAAAAAAAAATTCAAGGCATACTATACATAAGTGTAAGCATTGCAATTTTGTTTCAAGTAATTCTGCAGAATTCTTAATTCATAATTTACCAGGTAATTCAACTTGTAAGAAGCAATATTCGAAAAATGATACCCAGGCACAAAAACTTAACAAATTTGATAACTCACAAACAATACCCACAATTAATACTATTCAAAACAATCCAAATCCCAAACGATGTCAACAAACTACTATGAAGCAACCAGGGATTAACTATGCGTCTTCATCTGTCTGTGATCAATATTCTTATCTTGCTGCAGACACTTCGAATAGTAATAATCAAATGCTTAAACAAAATCAACCAATAATAACTGATCATCCAATAACAGGAAATACCACCCCTATTTATTATAAAAATCCAAATCCTAACAGTGGTGGAATGTCAATAGTGATCAATCAAACTACACCTACTGTTCAGAATATACCCACAATAGGAATCCTGCAACAACCAGCGCAGCAACAAATATATCAACAACAGGTATACAATGAACCAGTGACAATTATGAATACACCATACTTGTATCAACCACAAGATTTAGTTCAATTTTCCGAATCGAATGCTGTTTTCCAACTGGCAAATCAACCAAGTGTTACAACTTATCGAGTTAGATATGTATGTCCCTATTGTTCGAAAAGTTTTATTTCTGAAGACTATATGCAAATACATATAAATGAACACCACAATTTTATATGTAATATTTGTAATTTGCGTTTATACAGTTTTAACGATTTAAATCTTCATAAAATTCAGCATACTTTGTTGTAA
Protein Sequence
MEISNEELFSPHHLIDNYSEQIINMSLPLPKPKPKGSNAKYKKIQDTSCYILRKRLRSNRLKQLLRRGDTLEDLCKLLCKPVIVNVTKLSVSEIKQWCKKDLHQSQAKNILTQKKKFKRRIPRTRFYKRKKKSKQKQLSCLCNSENEVTPQNMLFSKEAEIENKNFIKNLLEDVKQPHIKLQRIDEVINKIAQSFARVTPIKECETIIQTECGTNIQSECETNIPTRCETSVQTRCETSIQTEETQTELSISASEQLKLSSVNIDTNKYQQNLKTETVAIRSHANETLQLNKCADLDSDSDSNTIFDFDSNTGNSRNTNERRHRIIYNSHTDDNNRYNKGNANNARIISNKLKRLRRNSSKKINKINLVNEKYNIIKKRCTGKNSLFQAPQRPSILDRISALCDPDDDDDDDDESTKEGNTSNCVPSKLNLECIIENDTSIKGKNEDAMTIEKPIVENKKIEGQVQESFPSDRNFTQRYKLSKELKVFLIKFDALKDSNTTYSATEIEKMTERFTNSYVNLNSSELQNSNEKSINNASFTSIFSKDSNVNIEKSTDAAKHVSSSSIDSITNKDVYTTTKRTQSTIKLLSNFSEKLSQNSIRNAKIQQERSSQIQKVCHNLTKIFEDSSEKRFAQNTISNAKQKLIVPTSTIKSTLLYSSQESTNKPSELSNVVENIDNIDKSTGKTFSLKKKIPEISSRKKNSMKLVIDARSQEQMGVDTSDVTNTKLHLSKKNKKHESEKRTFAPKTCGKTINVTTTKTATKKSASTSYSSTVSPKKYKRLRDDGYKCIVCDLCFEDYSDLQQHLITHTQKQNNSLANSLKTSNMSPEKSQDMISQFSKAKISEPSQVSSEHKSGEHTASQYVTKKDNGQQKKKDAITKSSLSKEKRKRRIKRISNSNKCSICSKPFEAMADLAAHIFLHTETELQQAYKLAKQKLNGTEKYKQTRTEQTANSIKNVNSTVNTADNIIERTQKVNDKEETLLIQKPNKSLITEDSEIRDAESITMKENYSQDIELCLPAKSKKDGNKKSFTVCECHNKPGTNENCLQIEIVLLCHTCRVLFRSMKCFETHYRLPEYIKCNQNHLTSGRSPNLFCATCGMIFSSVQDVRHHLEIHARFKKDCTMDFRCNICKVIFLGIGSLFYIHWSKHSRDSFWMASEKSFPKDSIINSKLRKAENSSTQNAMTLSTCVEKYIEVAEHVCYNCKLPFITQDDLKNHISECRKFKSVQDSSIAENSNTYLAIRITCSLCDDTFINKKTEFYKHMKDKHNLSTEPRFICTSFTAGNMVFICSVCTAMTKSLDDFEDHWLKHNTTHVYFTCSHCSKIYHNSLNSFIDHAKRHGIDANDVVSCVVNYEQTKFSCKLCNIGFDSPQSMQEHAIIHNTNSQQISPKIRQVTNQDSSATVSETDCASNIAKLVELTLQKQKMDGSLQMETQTMEKASEICPIESSIDKSRDELIKILEGNEDDSEHELIIDLTKQSEECNEGLKEEGSKERQTTSNLTLDKSSINQTCVMSENNKANALVTNVNVQVSSQNVAKSKTQNVTDSLFTAKSINPQISNSNIKSTNISQTILVSNNVSNHNNLLDIEKKISDQSITEDIESTQNVEVHDRISIINQEESTILTKETSEKQSPPRPRKGFLRVKTLAELTGSTNLCELSNCAVENGNELAKHFKSHHASNKDNNEHKTTEKELVSKQPEINKFIANKKLTIVPNTNSNTLLLSSSNSGNIKLVIQNPVMKSNTTIINNQQPQQFQIDTNQKEHSSSLENVTSAYHKNLPACNFVRTTTAMPRFTILKPTKVIAHTANIPNVQRTHVASCSTNENKQKSSSAKKNSRHTIHKCKHCNFVSSNSAEFLIHNLPGNSTCKKQYSKNDTQAQKLNKFDNSQTIPTINTIQNNPNPKRCQQTTMKQPGINYASSSVCDQYSYLAADTSNSNNQMLKQNQPIITDHPITGNTTPIYYKNPNPNSGGMSIVINQTTPTVQNIPTIGILQQPAQQQIYQQQVYNEPVTIMNTPYLYQPQDLVQFSESNAVFQLANQPSVTTYRVRYVCPYCSKSFISEDYMQIHINEHHNFICNICNLRLYSFNDLNLHKIQHTLL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00218063;
90% Identity
iTF_00226877;
80% Identity
-