Basic Information

Insect: Bombus impatiens
Gene Symbol: -
Assembly: GCA_000188095.4
Location: NT:1563337-1577289[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 18 3.5e-05 0.0022 17.5 1.4 1 23 447 469 447 469 0.96

2 18 0.0021 0.13 11.9 1.6 1 20 475 494 475 497 0.94

3 18 8.8e-06 0.00055 19.4 1.4 1 23 503 525 503 525 0.98

4 18 5.1e-05 0.0032 17.0 4.4 1 21 531 551 531 553 0.95

5 18 6.9e-06 0.00043 19.8 5.6 1 23 559 581 559 581 0.99

6 18 1.6e-05 0.00099 18.6 5.3 1 23 587 609 587 609 0.97

7 18 6e-05 0.0037 16.8 6.9 1 23 615 637 615 637 0.96

8 18 5.9e-08 3.7e-06 26.3 2.7 1 23 643 665 643 665 0.98

9 18 4.3e-05 0.0027 17.3 6.7 1 23 671 693 671 693 0.97

10 18 1.3e-05 0.00084 18.9 5.8 1 23 699 721 699 721 0.98

11 18 3.6e-07 2.2e-05 23.8 2.9 1 23 727 749 727 749 0.98

12 18 5.3e-06 0.00033 20.1 7.8 1 23 755 777 755 777 0.98

13 18 1.7e-05 0.001 18.6 9.1 1 23 783 805 783 805 0.98

14 18 2.2e-05 0.0014 18.2 7.5 1 23 811 833 811 833 0.98

15 18 0.0011 0.066 12.9 8.8 1 21 839 859 839 861 0.94

16 18 8.1e-06 0.0005 19.6 0.4 1 23 867 889 867 889 0.98

17 18 0.013 0.8 9.5 4.3 1 23 899 921 899 921 0.99

18 18 3.1e-07 1.9e-05 24.0 1.3 1 23 927 949 927 949 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	18	3.5e-05	0.0022	17.5	1.4	1	23	447	469	447	469	0.96
2	18	0.0021	0.13	11.9	1.6	1	20	475	494	475	497	0.94
3	18	8.8e-06	0.00055	19.4	1.4	1	23	503	525	503	525	0.98
4	18	5.1e-05	0.0032	17.0	4.4	1	21	531	551	531	553	0.95
5	18	6.9e-06	0.00043	19.8	5.6	1	23	559	581	559	581	0.99
6	18	1.6e-05	0.00099	18.6	5.3	1	23	587	609	587	609	0.97
7	18	6e-05	0.0037	16.8	6.9	1	23	615	637	615	637	0.96
8	18	5.9e-08	3.7e-06	26.3	2.7	1	23	643	665	643	665	0.98
9	18	4.3e-05	0.0027	17.3	6.7	1	23	671	693	671	693	0.97
10	18	1.3e-05	0.00084	18.9	5.8	1	23	699	721	699	721	0.98
11	18	3.6e-07	2.2e-05	23.8	2.9	1	23	727	749	727	749	0.98
12	18	5.3e-06	0.00033	20.1	7.8	1	23	755	777	755	777	0.98
13	18	1.7e-05	0.001	18.6	9.1	1	23	783	805	783	805	0.98
14	18	2.2e-05	0.0014	18.2	7.5	1	23	811	833	811	833	0.98
15	18	0.0011	0.066	12.9	8.8	1	21	839	859	839	861	0.94
16	18	8.1e-06	0.0005	19.6	0.4	1	23	867	889	867	889	0.98
17	18	0.013	0.8	9.5	4.3	1	23	899	921	899	921	0.99
18	18	3.1e-07	1.9e-05	24.0	1.3	1	23	927	949	927	949	0.97

Sequence Information

Coding Sequence: ATGAACAGTGAGCAGCATGCATTGCCAGCGACTACGCAGGCACAGCAAGAGGATGTAAACGCGGGTCAAAGTGGTCGTCCTTCATACCCAGGTGGTTTGGCTACAACAACCAGTCTTGGCAATGTAGGGAGTACCCCGCATTCATCCGCGGACCTGCGTGTAGGTACAGCCGTAGCGTTAGCCTCCTCGGTAGCTAAATATTGGGTCCTCACCAATCTCTTTCCTGGACCGCTACCTCAGGTCTCAGTCTATCATCATTCCCACCACAACTCCTCACATAGGAGTAGTGGAGGTGGAGAGGCATCTTCCAAAGAGCCAGCCTCTTCATTGAACCAAGAAATGGCGTTGACTTCCAGTTCACATCATCAGTCAACACCTACACACCATCATCACCAACCTTCAGTTAGCAGTAGCAGTCATCATAGTTCTTTACAACCAAATTCACAGcaGATACCAGTTTCTCTACCAGGCCTTAATTTAGACGGGGCACATATACCTGCCAGCGTCAGTCATTTACAAGCAGCACATGCACAAATGCAACAAATGCAGGCagcacaacaacaacagctgcatcagcagcaacagcaacagccccaacaacaacaacagcagcagcagcaacaatcTCACCATCAGATGCAAAGTCATCAGAACGCTCAGAACAGTGGACCAACTGCACATAATCAAAACGCACAGAGAGATGATAACAAGGTGAAAGATGAAAGTGGAAGTTGCACAACTGAACGTTGCAGTGACAATCAAGTTCACTGTCAAGTTCAATGTGACCTCCAATTACAAACATCTCAAGATTTACAACAAAGTCTTAtgcaacagcagcaacaacagcagcaacaaaTTGGTGTAAACATAAGCGGAAATTCATCGAGTGAAGGCGGAAGtcaaaataatacagaaaagcctgaaaaagagaaagaattgCGTCAACTAAATATGACGCAATTCCAAGTGCCAGATTTAAAACCAGGAGGTCATATGATGGATGTAAGAACAGCTGATGGATCAGTCGTGAAGATTAGCGCTGGGAACGAACAAGATTTAGCAAAAACACTTGGTGTTGAAATGGTGCAAAATATGTACAAGGTAAATGTCGAAGACATTAATCAGCTTTTAGCATATCATGAAGTATTTGGAAAACTACAAAGTGAAATAGCAGCTGGTACAACTTTAGTTGGAAGTACAGTTCCTACTCAAACAGTTACCACTATACAAAATGGAACTCCAATTGTACAACAAGTTCAATTAAATAAGTTTGATATTAAATCAAGCGATGGCGAAGCTACACCAGGACCAAGCGCTTCGCCTGTGTCGGTTGGAAGTCATGCATGTGAAATATGTGgaaaaatttttcagtttcgCTATCAGCTTATCGTTCATCGTAGATATCATACGGAAAGGAAACCTTTTACTTGTCAGGTGTGTGGCAAGGCCTTCTTAAATGCAAACGATTTGACACGGCATGGGAAGTGTCACCTAGGTGGATCCATGTTTACTTGTACAGTTTGTTTTCATGTATTTGCAAATGCGCCCTCTTTGGAACGTCATATGAAGCGACACGCTACCGATAAACCGTATAATTGTACCGTATGTGGAAAAAGCTTTGCAAGAAAAGAACATTTGGATAATCATACGCGTTGTCATACTGGGGAAACACCTTATAGatGCCAGTACTGTTCAAAGACGTTTACTAGGAAGGAACATATGGTAAATCATGTTCGCAAACATACGGGTGAAACACCTCATCGAtgtgatatttgtaaaaagagCTTTACCCGCAAAGAACATTTTATGAACCATGTTATGTGGCACACGGGAGAAACTCCTCATCATTGTCAAGCTTGTGGCAAGAAATATACACGTAAAGAACATCTCGCAAATCATATGCGTTCACATACCAATGATACACCGTTTCGCTGTGAAATATGCGGTAAGTCGTTTACAAGAAAGGAGCACTTCACGAACCACATAATGTGGCACACGGGTGAGACGCCGCATCGCTGTGATTTCTGCTCGAAGACATTCACGCGAAAGGAGCATCTCTTGAACCACGTTCGCCAGCACACGGGTGAGTCTCCACACCGATGCGGCTTCTGCTCCAAATCGTTCACCAGAAAGGAACACCTTGTTAACCACATCCGCCAACACACAGGAGAGACGCCCTTCCGCTGTCAGTACTGTCCAAAAGCATTTACGCGGAAGGATCATCTGGTGAACCATGTCAGGCAACACACGGGTGAGTCACCGCACAAGTGCCAGTATTGCACCAAATCCTTCACGAGGAAGGAACATTTGACAAATCACGTGCGTCAACACACAGGCGAATCGCCACACCGATGCCACTTCTGCTCCAAGTCATTTACTCGTAAGGAGCATTTGACGAATCATGTGCGAATCCACACTGGTGAATCACCTCATAGGTGTGAATTCTGTCAGAGAACGTTCACCAGGAAAGAACATCTAAATAATCATCTCCGTCAGCATACCGGAGATTCATCGCACTGCTGCAACGTGTGCTCGAAACCATTTACAAGAAAGGAACATCTCGTAAATCATATGCGATGTCATACTGGTGAACGTCCATTTGTATGCACAGAATGTGGCAAAAGCTTCCCTTTAAAGGGGAATCTACTTTTCCACATGCGTTCGCACAATAAAGGCAGCAACGCCGAGAGACCGTATCGTTGTGATCTTTGTCCAAAAGACTTTATGTGCAAAGGACATTTAGTGTCTCATAGACGATCACATTCGGACGAGCGACCACATAGCTGTCCAGATTGCGGGAAAACTTTCGTTGAAAAGGGCAATATGCTGAGACACTTGAGAAAACACGCAGCGGAAGGTCCGCCAACACAAGTTAGCACGCCCTCTGCAATTCCTCAATCCGGTGTTCTGCCCATTCCGGCAGCAGCAGTTCTGGTCGGCCATCCTTTGGCACCCCCTGCACCACCCGTAGTCCCACAACATACCGTAGTTGTGCCTACTCCTCCGGGTGTACTGACCTCCTACTAA
Protein Sequence: MNSEQHALPATTQAQQEDVNAGQSGRPSYPGGLATTTSLGNVGSTPHSSADLRVGTAVALASSVAKYWVLTNLFPGPLPQVSVYHHSHHNSSHRSSGGGEASSKEPASSLNQEMALTSSSHHQSTPTHHHHQPSVSSSSHHSSLQPNSQQIPVSLPGLNLDGAHIPASVSHLQAAHAQMQQMQAAQQQQLHQQQQQQPQQQQQQQQQQSHHQMQSHQNAQNSGPTAHNQNAQRDDNKVKDESGSCTTERCSDNQVHCQVQCDLQLQTSQDLQQSLMQQQQQQQQQIGVNISGNSSSEGGSQNNTEKPEKEKELRQLNMTQFQVPDLKPGGHMMDVRTADGSVVKISAGNEQDLAKTLGVEMVQNMYKVNVEDINQLLAYHEVFGKLQSEIAAGTTLVGSTVPTQTVTTIQNGTPIVQQVQLNKFDIKSSDGEATPGPSASPVSVGSHACEICGKIFQFRYQLIVHRRYHTERKPFTCQVCGKAFLNANDLTRHGKCHLGGSMFTCTVCFHVFANAPSLERHMKRHATDKPYNCTVCGKSFARKEHLDNHTRCHTGETPYRCQYCSKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHFMNHVMWHTGETPHHCQACGKKYTRKEHLANHMRSHTNDTPFRCEICGKSFTRKEHFTNHIMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCGFCSKSFTRKEHLVNHIRQHTGETPFRCQYCPKAFTRKDHLVNHVRQHTGESPHKCQYCTKSFTRKEHLTNHVRQHTGESPHRCHFCSKSFTRKEHLTNHVRIHTGESPHRCEFCQRTFTRKEHLNNHLRQHTGDSSHCCNVCSKPFTRKEHLVNHMRCHTGERPFVCTECGKSFPLKGNLLFHMRSHNKGSNAERPYRCDLCPKDFMCKGHLVSHRRSHSDERPHSCPDCGKTFVEKGNMLRHLRKHAAEGPPTQVSTPSAIPQSGVLPIPAAAVLVGHPLAPPAPPVVPQHTVVVPTPPGVLTSY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00899003;
90% Identity: iTF_00625640;
80% Identity: iTF_00232113;