Bhor000210.1
Basic Information
- Insect
- Bombus hortorum
- Gene Symbol
- -
- Assembly
- GCA_905332935.1
- Location
- HG995201.1:2006234-2010134[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 6.5 6.9e+02 1.3 0.2 1 20 368 387 368 391 0.77 2 10 0.027 2.8 8.8 3.8 1 23 398 420 398 420 0.97 3 10 0.00064 0.068 13.9 4.0 1 20 426 445 426 448 0.96 4 10 1.3e-06 0.00014 22.4 1.7 1 23 454 476 454 476 0.98 5 10 4.2e-05 0.0045 17.6 3.3 1 23 482 504 482 504 0.98 6 10 2.9e-06 0.00031 21.3 0.7 1 23 515 537 515 537 0.98 7 10 1.2e-08 1.3e-06 28.8 0.3 1 23 543 565 543 565 0.99 8 10 6.7e-06 0.00072 20.1 0.6 1 23 571 593 571 593 0.95 9 10 8.9e-06 0.00095 19.8 0.1 1 23 599 621 599 621 0.93 10 10 1.6e-05 0.0017 18.9 0.2 3 23 629 649 627 649 0.98
Sequence Information
- Coding Sequence
- ATGAATTGGGAAATTAGCTGTGCTGACATGTGTCGAGCGTGCATGAAAGTTGACGGCGTTCTTCTTCCTATGTACGATGACGACACGATTAGTCAAAAAAATTTGCCTAATAAACTTGCAGAACTTGCATCGATACAGATTGACAGGTTCGATGGGTTACCAAATATGCTTTGTGCAAAGTGTGCTTATCGCACAGATGCATTTTATGATTTCAAGTTGCAAGTTCAAGCTACTGAAAGGAAACTCCGCAAAATGTTTGAAACACAAATCCGCTATAACATAAAGGAGGAGCCAATGGACAATGATTTTGAACAAGACTGTTCAGAACAGTCAGACGAATTGATAGAAATTAAATTATTAGATAACAAAGAAGATATTAGGCCTACCAATGGTACGGATAATTCAGAAGAATTTTTGTCCGAGCGAATTACTATAAACGAGAAAGTGGAGCAAGCGTTAGAGCTCGACGTGTCCGAACTGGTAGAAGAAAATGGCGAATTTAACAAGGCTAGCATATCTGAATTGAAAGGTATTATCATTTCGAAGCTGTCAGGAGCAGAGATCGATCAAGACAAACGACTGAAGAACGAGATACCTGATGAAATTTCGAAAATTTTGGAATCCCAGCAGCTAGATTATACCATAATGTATATACCGGAAGATGTTTCTTTAGAGCATGTAGAGCATGTAGAGCATGCGAATACCCAGAATACGCTTTCTTGCGATACTGTGATTAAATTAGAAGATAGCAAAAAGATTACCGAGGCTGACTGTAATGGGGAGCTCCTACACGAAACGGTGGACAACGAAGAATTTTTAAATGCCGTGTGCAACGAGAAGATCGTGGAATCAAGGGAGGAAGATAATAAAACCAGCGACGACGAGGTGGCCTGGAAACCTACGATTTCGGAAGAAAAATCGATGGAAAGACTAAACGAGAAAAACACACAAAAACATTCGCCGGAATCGAATCAACAGCCAGAAGAGAGCGATGACTCTGACTCCGATTATTTTGTCGACCCGAAAGATAATATATTAGGTAGCTTGAATGATACAATAACGAGAATAAAGGAGATAAAACTCGAAGACGACGTGATACAGTATCAGTGCACTCTGTGTTTGCAAAATTACGATAAGCTGACCGGTGTCTTGTTGCATACTATAGACAATCATGTGCCGAGTAGCGGTCCATTCTTTTGCGTGGTATGCGAGAAAGACTGCCAGAGTCATAGAGAATTGCGTGCGCATGTTAAAACGCATAGAGGCCAGTTCCCATATTCCTGTTTCATATGCAACAAAGCTTACACGATGAAGAGGTATTTAAAGAGACATATGGTGTGTCACACGGAGTTTCATAGGCATCGTTGTCCAAAATGCGGCCTCAGATTCAAAGTTAAATCAGAGTTAGAAACTCACATTACGACACACATACGCGGTGCGCCTTACTCCTGTAGTCAATGTCCACGACTGTTCAATCATAAAGGTAACTACAAGCGGCATTTGATTACTCACTTGGATCCGCAAGGTCTTCACTTACCCAAGTATCCCTGTAAAGTTTGTGGAAAAAGATTTCTAAATAATCGCACATTAGAGACACATATGCGCGTTCACACAGGTGAAAAACCGTTCAAATGCGAGATATGTGGACGATCGTTCTCTCAACAAGGAAATTTGTTGAATCATGTAAGAATCCACTCAAACCCGCGAAGCTACACGTGCGAGGTTTGCGGAAAGCGATTCAACCAAAGGGCCACTTTGAGAGATCATAGTCTTCTACACACTGGAGAAAAACCATATGTTTGTAATGTTTGCGGAATAGCGTTTACTTTTAGCGCCGCGTTGAGACGCCACATGTGGACTCATACTGGTGGAAAACCATTCGGATGTGAAATTTGTAGTGCTCGTTTCGTGGGCAAATATGATTTACGACGACATATGAGGATACACACGGATAGACCGAGAACGAAACGAAGAAAAAACGTGATCAAATCGAACAATGAACAGGAAGCAATTAAAGAAGAAGATGTTACAGTTTCGGAACATCCTGACACAGAGACTGTTTTAATAGAACAAGTTTTGTTAACGCAAAACGTTACGCAGGTTGTGCAACAAGAGTCTGAGAAGGAAAATGTCGATGCTCTTTTTAATCTTATACAATATGGTTAA
- Protein Sequence
- MNWEISCADMCRACMKVDGVLLPMYDDDTISQKNLPNKLAELASIQIDRFDGLPNMLCAKCAYRTDAFYDFKLQVQATERKLRKMFETQIRYNIKEEPMDNDFEQDCSEQSDELIEIKLLDNKEDIRPTNGTDNSEEFLSERITINEKVEQALELDVSELVEENGEFNKASISELKGIIISKLSGAEIDQDKRLKNEIPDEISKILESQQLDYTIMYIPEDVSLEHVEHVEHANTQNTLSCDTVIKLEDSKKITEADCNGELLHETVDNEEFLNAVCNEKIVESREEDNKTSDDEVAWKPTISEEKSMERLNEKNTQKHSPESNQQPEESDDSDSDYFVDPKDNILGSLNDTITRIKEIKLEDDVIQYQCTLCLQNYDKLTGVLLHTIDNHVPSSGPFFCVVCEKDCQSHRELRAHVKTHRGQFPYSCFICNKAYTMKRYLKRHMVCHTEFHRHRCPKCGLRFKVKSELETHITTHIRGAPYSCSQCPRLFNHKGNYKRHLITHLDPQGLHLPKYPCKVCGKRFLNNRTLETHMRVHTGEKPFKCEICGRSFSQQGNLLNHVRIHSNPRSYTCEVCGKRFNQRATLRDHSLLHTGEKPYVCNVCGIAFTFSAALRRHMWTHTGGKPFGCEICSARFVGKYDLRRHMRIHTDRPRTKRRKNVIKSNNEQEAIKEEDVTVSEHPDTETVLIEQVLLTQNVTQVVQQESEKENVDALFNLIQYG
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00118167;
- 90% Identity
- iTF_00217898;
- 80% Identity
- -