Basic Information

Insect: Bombus hortorum
Gene Symbol: -
Assembly: GCA_905332935.1
Location: HG995192.1:3229700-3233626[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 19 2 2.2e+02 2.9 7.1 1 23 27 50 27 50 0.92

2 19 3e-06 0.00032 21.2 0.3 1 23 56 78 56 78 0.97

3 19 1.8e-05 0.002 18.8 1.4 1 23 84 106 84 106 0.97

4 19 0.0002 0.021 15.5 0.5 1 23 112 134 112 134 0.98

5 19 2.3e-06 0.00025 21.6 7.0 1 23 140 162 140 163 0.96

6 19 0.0017 0.18 12.6 2.1 1 23 179 202 179 202 0.96

7 19 0.0092 0.99 10.3 0.6 3 23 212 232 210 232 0.95

8 19 6.2e-07 6.6e-05 23.4 0.4 2 23 239 260 238 260 0.98

9 19 0.00035 0.038 14.7 0.7 3 20 268 285 266 287 0.94

10 19 0.095 10 7.1 0.7 2 23 322 344 321 344 0.96

11 19 7.8e-06 0.00083 19.9 0.8 1 23 350 373 350 373 0.97

12 19 0.059 6.2 7.7 0.5 2 23 379 400 378 401 0.94

13 19 2.4e-05 0.0026 18.4 0.5 1 23 406 428 406 428 0.98

14 19 0.00019 0.02 15.6 0.5 2 23 435 457 434 457 0.94

15 19 5.8e-05 0.0062 17.2 2.1 1 23 479 502 479 502 0.93

16 19 0.0019 0.2 12.4 0.1 1 23 513 535 513 535 0.95

17 19 0.0073 0.78 10.6 3.6 1 23 541 563 541 563 0.94

18 19 4.5e-07 4.8e-05 23.8 1.1 1 23 569 591 569 591 0.98

19 19 1.6e-05 0.0017 19.0 0.1 1 21 597 617 597 618 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	19	2	2.2e+02	2.9	7.1	1	23	27	50	27	50	0.92
2	19	3e-06	0.00032	21.2	0.3	1	23	56	78	56	78	0.97
3	19	1.8e-05	0.002	18.8	1.4	1	23	84	106	84	106	0.97
4	19	0.0002	0.021	15.5	0.5	1	23	112	134	112	134	0.98
5	19	2.3e-06	0.00025	21.6	7.0	1	23	140	162	140	163	0.96
6	19	0.0017	0.18	12.6	2.1	1	23	179	202	179	202	0.96
7	19	0.0092	0.99	10.3	0.6	3	23	212	232	210	232	0.95
8	19	6.2e-07	6.6e-05	23.4	0.4	2	23	239	260	238	260	0.98
9	19	0.00035	0.038	14.7	0.7	3	20	268	285	266	287	0.94
10	19	0.095	10	7.1	0.7	2	23	322	344	321	344	0.96
11	19	7.8e-06	0.00083	19.9	0.8	1	23	350	373	350	373	0.97
12	19	0.059	6.2	7.7	0.5	2	23	379	400	378	401	0.94
13	19	2.4e-05	0.0026	18.4	0.5	1	23	406	428	406	428	0.98
14	19	0.00019	0.02	15.6	0.5	2	23	435	457	434	457	0.94
15	19	5.8e-05	0.0062	17.2	2.1	1	23	479	502	479	502	0.93
16	19	0.0019	0.2	12.4	0.1	1	23	513	535	513	535	0.95
17	19	0.0073	0.78	10.6	3.6	1	23	541	563	541	563	0.94
18	19	4.5e-07	4.8e-05	23.8	1.1	1	23	569	591	569	591	0.98
19	19	1.6e-05	0.0017	19.0	0.1	1	21	597	617	597	618	0.96

Sequence Information

Coding Sequence: ATGTCTTCCTTAGAAGAAAAAAAACCAGAGCAAATTTATTTGTATTATCGATCGCGAAGAGCAATTTCTCGAGCAATTCACGAATGCATCAAATGCGGAGCCTGCTTCTGTCACATGAGAAAGCTGGTAGAACACCTGAAGAACCTCCATGGTATCGACAGAGCCTTCAGCTGCGACGAGTGCGGCAAAACTTTCAGAAGTCCCATGAACATAGCTCGTCACAAATTAATTCACACTGGTTTCAAAAAATTCGCCTGCGACTTATGCGACTATAGATCAAACCAAAAGTCAAACCTCGAGAGCCATCGTCGAAGACACACCAAAGACTATTCCTTTAAATGCGAACAATGTGGAAAAGGCTTCTTCCTGAGAACAGAATACTTGGAACATATAAATGTTCATACTAGGAAGCTATTGTACAAATGTGATCACTGTAGCAAGTCATACCCTTACAAGAAGAACCTGACAAATCACTTAAGAACGCATCATGCGAGTGTCTCGCAGTTAGAATTAAGAAATGACGTGACAAAGAAGCACGTGTGCACAATTTGCCTGGAGGGTTTCACGCGAAAATTGTTCTTGGAAAGGCACTTGAAGCAACGACACGGTTTGTACGAGAAAATGAAGCATTTATGCGATCTGTGCGGCGCAGTGTTGTCTTCCAAGAGGAGGTTGATGGTGCATAGGCGGGGCCACGTTAACGAGAAGATCGTAAAATGCGATTTATGCGACAAGCAGTTCTCTAGCAAGGAAAACCTCGCTGTTCATCGGCGAGTGCACACTGGGGAGAAACCGTACGGTTGCTCGCAGTGTGGAAGAAGGTTTACACAGAGGACTTCTTTGATATTACATCTTAGCCACTGGGGCAACGATCACGACGTGCTTAGCAGCTGCGAAGATTTCAGAATCAAGAACGAGGATATTCTTCTCGATCCTGGACAAAAGTTCGAGGGGAACGAGAAAGTCTGCGACCTTTGTCAAGAAAAATTCCACTTCGTAACCAGATTAGTAGCTCATCTGAGGATCGTCCACGGTATCCATAGACCCTTCAAATGTGCCACATGTGGGAAGACATATCCGCAGCAGTTCATGCTAAACGCCCATGTGAAAAAATCTCACACTCCTAAAACGATCCCCTGCACTGAATGTAGTTTCATGGGGGTGAATGCCACTGACGTGGAAAGACATACGAAACGACACCATCGAGAAATGAAGTTCACCTGTGAAATCTGTAGCGAGAACTTCGTAGACAAGGATTCCTTGATGACTCACACAACTATGCATAACTTTATGCAGTTTCAACAATGTAACGCTTGTGGTACTACGTTCAACGACGCGTACAGCCTAAAGGAGCACAACCGTTTGTACCACTACGATCCAACAACGTTGATTCAAGAGAAGCTGGAAGCTGACAGTCCGCAGAACACCACGGAGCACAAATGCGACGTCTGTGGGAAGGTTTACAAGTACAAATCGGTCTTGAAGCAACACAAAGTGAAAGCTCACGGTGATATGCCAAATTACGAGAGACGTCGATATTTATGCGCTCTTTGCGGGAAAGAATTGAAAACCGCGAAAGGCCTCGAAATTCACAATCGATCGCACACCGGCGAAAAGCCTTACACCTGCGAGGTGTGTGGCAAGTGTTTCGCCTGTGAGACACTGCTCAGGACTCATAATGTCACGCACACTGGCGAGAGAAAGTATTCTTGCGACCAGTGTGGCAAAGCTTTCACGCAGAGATCCACGTTGGTCGTGCATAAACGTTATCATACCGGCGAACGACCGTATGTTTGTCCTCGATGTGGAAAAGGTTTCGTCACCAGGACCGTCCTGAACACTCACATGAAATCCTGCCGTTGA
Protein Sequence: MSSLEEKKPEQIYLYYRSRRAISRAIHECIKCGACFCHMRKLVEHLKNLHGIDRAFSCDECGKTFRSPMNIARHKLIHTGFKKFACDLCDYRSNQKSNLESHRRRHTKDYSFKCEQCGKGFFLRTEYLEHINVHTRKLLYKCDHCSKSYPYKKNLTNHLRTHHASVSQLELRNDVTKKHVCTICLEGFTRKLFLERHLKQRHGLYEKMKHLCDLCGAVLSSKRRLMVHRRGHVNEKIVKCDLCDKQFSSKENLAVHRRVHTGEKPYGCSQCGRRFTQRTSLILHLSHWGNDHDVLSSCEDFRIKNEDILLDPGQKFEGNEKVCDLCQEKFHFVTRLVAHLRIVHGIHRPFKCATCGKTYPQQFMLNAHVKKSHTPKTIPCTECSFMGVNATDVERHTKRHHREMKFTCEICSENFVDKDSLMTHTTMHNFMQFQQCNACGTTFNDAYSLKEHNRLYHYDPTTLIQEKLEADSPQNTTEHKCDVCGKVYKYKSVLKQHKVKAHGDMPNYERRRYLCALCGKELKTAKGLEIHNRSHTGEKPYTCEVCGKCFACETLLRTHNVTHTGERKYSCDQCGKAFTQRSTLVVHKRYHTGERPYVCPRCGKGFVTRTVLNTHMKSCR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00361060;
90% Identity: iTF_00684909;
80% Identity: iTF_00217213;