Bdif013504.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus difficillimus
Gene Symbol
-
Assembly
GCA_014737525.1
Location
JACXIT010000097.1:1072508-1073602[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 4.7e-05 0.0044 17.5 3.2 1 23 93 115 93 115 0.98
2 9 3.2e-07 3e-05 24.4 0.6 1 23 121 143 121 143 0.98
3 9 0.00015 0.014 15.9 1.7 1 23 148 171 148 171 0.97
4 9 1.5e-05 0.0014 19.1 0.5 1 23 177 199 177 199 0.97
5 9 2.4e-05 0.0022 18.5 0.2 1 23 205 228 205 228 0.97
6 9 6.3e-07 5.9e-05 23.4 0.5 1 23 238 260 238 260 0.94
7 9 2e-05 0.0018 18.8 1.8 1 23 264 286 264 286 0.95
8 9 6.7e-06 0.00063 20.2 0.1 1 23 292 314 292 314 0.98
9 9 3.9e-07 3.7e-05 24.1 1.0 1 23 320 342 320 342 0.99

Sequence Information

Coding Sequence
ATGTTGAAAAATCACGTTGTTGATTGCAGAACTCTCGAGGTCGTACAGTGGGACGCGAAATCCAAAGACTGCGGCGACCAGGCCATCAAGATCTTCGAATCAAGATCACTCATATCGTCAGAACCATCGCCAGAACCATCGCAAGTGAATCCTTCGTCTGATAGAAAAGATCGTACCTCGAAGGAGCCAAATTACCTTACGAATTCTGACAACGATTCACTGACAAATTCATCTACAAAGAGGAGGAAGAATAAAAGATTCGAAGATCAAGAACAATACATCTGCTCCACCTGCAAGTTACATTTTGACAGACAAGGAGACTACAAGCGTCACATGATCAAGCACAGCGATCTTCGTCCTTACAAATGCGAAATCTGCGACAAGGCGTTTAAACGTTCCTCAGAGGTGTCCAACCACACTCAGATCCACCGTGGTATCGAATACGCGTGCGAAGTATGCGGTTTCACTACGATAAATAAATTCTCTTTAAGAATGCATCATCGTCGAGTTCACCAGCGTGACTTTCGTTATCGTTGCGATCAATGTGACAAGGGTTTCATGTCTAATTACGATCTGGAGGACCACAAGGCCAGTCATCTAGGCAGAAAGACCTTCATTTGCGAATTCTGTGGCAACGCCTACTCCCAAAAATCCTACTTGGTAGCACACAAACGGGTAATTCATAGAATTCAAAAGAGCGCGCCGAAGGAGTTCCAGTGTAATATCTGCAACAAGAGTTTCGCTACCGAGCAGAATCTTCGTAATCACGTTGGTCTACACTCGCAAATGTTCCTGTGCGCCCAGTGTGGCAAAAAATTCGCAACCAATCACGCTTTGAAGCTTCACGGTCGAAAACACACGGGGGAGAGACCTTACGAGTGTATGGTTTGCTCGAAAGCTTTCGCCAGATCGGCTGCGCTCAGAGTGCATAAATTAACACACACGGGCGAGAGACCATACGTGTGTGACCTGTGCGGGCAGAGTTTTACTCAGAGAAGTAGCATGATGGTGCATCGACGAAAACACCCCGGAAGTCATCCTCCGCCTCCTCCTCTACTTCTTAGCAGACTCGAGAGCAATGGACATAAGTTATAG
Protein Sequence
MLKNHVVDCRTLEVVQWDAKSKDCGDQAIKIFESRSLISSEPSPEPSQVNPSSDRKDRTSKEPNYLTNSDNDSLTNSSTKRRKNKRFEDQEQYICSTCKLHFDRQGDYKRHMIKHSDLRPYKCEICDKAFKRSSEVSNHTQIHRGIEYACEVCGFTTINKFSLRMHHRRVHQRDFRYRCDQCDKGFMSNYDLEDHKASHLGRKTFICEFCGNAYSQKSYLVAHKRVIHRIQKSAPKEFQCNICNKSFATEQNLRNHVGLHSQMFLCAQCGKKFATNHALKLHGRKHTGERPYECMVCSKAFARSAALRVHKLTHTGERPYVCDLCGQSFTQRSSMMVHRRKHPGSHPPPPPLLLSRLESNGHKL