Bdif013515.1
Basic Information
- Insect
- Bombus difficillimus
- Gene Symbol
- -
- Assembly
- GCA_014737525.1
- Location
- JACXIT010000097.1:1110894-1114446[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 19 1.7 1.6e+02 3.2 7.4 1 23 33 56 33 56 0.92 2 19 3.2e-06 0.0003 21.2 0.3 1 23 62 84 62 84 0.97 3 19 2e-05 0.0018 18.7 1.4 1 23 90 112 90 112 0.97 4 19 0.0016 0.15 12.7 0.6 1 23 118 140 118 140 0.98 5 19 2.5e-06 0.00023 21.6 7.0 1 23 146 168 146 169 0.96 6 19 0.0018 0.17 12.6 2.1 1 23 185 208 185 208 0.96 7 19 0.0099 0.92 10.3 0.6 3 23 218 238 216 238 0.95 8 19 6.6e-07 6.2e-05 23.4 0.4 2 23 245 266 244 266 0.98 9 19 0.00038 0.035 14.7 0.7 3 20 274 291 272 293 0.94 10 19 0.1 9.5 7.1 0.7 2 23 328 350 327 350 0.96 11 19 1.1e-05 0.001 19.5 0.9 1 23 356 379 356 379 0.97 12 19 0.2 19 6.1 0.3 2 23 385 406 384 407 0.93 13 19 6.7e-05 0.0063 17.1 0.6 1 23 412 434 412 434 0.98 14 19 0.0002 0.019 15.6 0.5 2 23 441 463 440 463 0.94 15 19 6.2e-05 0.0058 17.2 2.1 1 23 485 508 485 508 0.93 16 19 0.002 0.19 12.4 0.1 1 23 519 541 519 541 0.95 17 19 0.0078 0.73 10.6 3.6 1 23 547 569 547 569 0.94 18 19 4.8e-07 4.5e-05 23.8 1.1 1 23 575 597 575 597 0.98 19 19 1.7e-05 0.0016 19.0 0.1 1 21 603 623 603 624 0.96
Sequence Information
- Coding Sequence
- ATGTCTTGCACATTTATTCCTTCATTATCTAAATTACTTCGTGCACTTCATCGTTGTTTCTGTTTCAGATCGCGAAGAGCAATTTCTCGAGCAATTCACGAATGCATCAAATGTGGAGCCTGCTTCTGTCACACGAGGAAGCTGGTAGAACACCTGAAGAACCTCCACGGTATCGACAGAGCCTTCAGCTGCGACGAGTGCGGCAAAACGTTCAGAAGTCCCATGAACATAGCTCGTCACAAATTAATTCACACTGGTTTCAAAAGATTCGCTTGCGACTTATGCGACTATAGATCAAATCAAAAGTCAAACCTCGAGAGCCATCGTCGAAGACACACCAAGGACTATTCCTTTAAATGCGAACAATGTGAAAAAGGCTTCTTCCTGAGAACAGAATACTTAGAACATATAAATGTTCATACTAGGAAGCAATTGTACAAATGCGATCACTGTAGCAAGTCATACCCTTACAAGAAGAACCTGACAAATCACTTAAGAACGCATCATGCGAGTATCTCGCAGTTAGAATTAAGAAACGACGTGACAAAGAAGCACGTGTGCACAATTTGCCTGGAGGGTTTCACGCGAAAATTGTTCTTGGAAAGGCACTTGAAGCAACGACACGGTTTGTACGAGAAAATGAAGCATTTATGCGATCTGTGCGGAGCAGTGTTGTCTTCCAAGAGGAGGTTGATGGTGCATAGGCGGGGCCACGTTAACGAGAAGATCGTAAAATGCGATTTATGCGACAAGCAGTTCTCTAGCAAAGAAAACCTCGCTGTTCATCGGCGAGTGCACACTGGGGAGAAACCGTACGGTTGCTCGCAGTGTGGAAGAAGGTTTACACAGAGGACTTCTTTGATATTACATCTTAGCCACTGGGGCAACGATCACGACGTGCTTAGCAGCTGCGAAGATTTCAGAATCAAGAACGAGGATATTCTTCTCGATCCTGGACAAAAGTTCGAGGGGAACGAGAAAGTCTGCGACCTTTGTCAAGAAAAATTCCACTTCGTAACCAGATTAGTGGCTCATCTGAGGATCGTCCACGGTATCCATAGACCCTTTAAATGTGTCACGTGTGGGAAGACATATCCGCAGCAGTTTATGCTAAACGCCCATGTGAAAAAATCTCACACTCCTAAAACGGTCCCCTGCGCTGAATGCAGTTTCATGGGGGTGAATGCCACTGACGTGGAAAGACATACGAAACGACACCATCGAGAAACGAAGTTCACCTGTGAAATCTGTAGCGAGAACTTCGTAGACAAGAATTCCTTGATGACTCACACAACTATGCATAACTTTATGCAGTTTCAACAATGTAACGCTTGTGGTACTACGTTCAACGACGCGTACAGCCTAAAGGAGCACAACCGTTTGTACCACTACGATCCAACAACGTTGATTCAAGAGAAGCTCGAAGCTGACAGTCCGCAGAACACCACGGAGCACAAATGCGACGTCTGTGGGAAGGTTTACAAGTACAAATCGGTCTTGAAGCAACACAAAGTTAAAGCTCACGGTGATATGCCAAATTACGAGAGACGTCGATATTTATGCGCTCTTTGCGGGAAAGAATTAAAAACCGCAAAAGGCCTCGAAATTCACAATCGATCGCACACCGGCGAAAAGCCTTACACCTGCGAGGTGTGTGGCAAGTGTTTCGCCTGTGAAACATTGCTCAGGACTCATAATGTCACGCACACTGGCGAGAGAAAATATTCTTGCGACCAGTGTGGCAAAGCTTTCACGCAGAGGTCCACGTTGGTCGTGCATAAACGTTATCATACCGGCGAACGACCGTATGTTTGTCCTCGATGTGGAAAAGGTTTCGTCACCAGGACTGTCCTGAACACTCACATGAAGTCCTGCCGTTGA
- Protein Sequence
- MSCTFIPSLSKLLRALHRCFCFRSRRAISRAIHECIKCGACFCHTRKLVEHLKNLHGIDRAFSCDECGKTFRSPMNIARHKLIHTGFKRFACDLCDYRSNQKSNLESHRRRHTKDYSFKCEQCEKGFFLRTEYLEHINVHTRKQLYKCDHCSKSYPYKKNLTNHLRTHHASISQLELRNDVTKKHVCTICLEGFTRKLFLERHLKQRHGLYEKMKHLCDLCGAVLSSKRRLMVHRRGHVNEKIVKCDLCDKQFSSKENLAVHRRVHTGEKPYGCSQCGRRFTQRTSLILHLSHWGNDHDVLSSCEDFRIKNEDILLDPGQKFEGNEKVCDLCQEKFHFVTRLVAHLRIVHGIHRPFKCVTCGKTYPQQFMLNAHVKKSHTPKTVPCAECSFMGVNATDVERHTKRHHRETKFTCEICSENFVDKNSLMTHTTMHNFMQFQQCNACGTTFNDAYSLKEHNRLYHYDPTTLIQEKLEADSPQNTTEHKCDVCGKVYKYKSVLKQHKVKAHGDMPNYERRRYLCALCGKELKTAKGLEIHNRSHTGEKPYTCEVCGKCFACETLLRTHNVTHTGERKYSCDQCGKAFTQRSTLVVHKRYHTGERPYVCPRCGKGFVTRTVLNTHMKSCR
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00361060;
- 90% Identity
- iTF_00216535;
- 80% Identity
- -