Basic Information

Insect: Bombus difficillimus
Gene Symbol: ZNF236
Assembly: GCA_014737525.1
Location: JACXIT010000133.1:2118793-2126813[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 26 0.0024 0.22 12.2 2.1 2 23 176 197 175 197 0.96

2 26 0.00011 0.0099 16.5 1.1 1 23 203 225 203 225 0.98

3 26 3.2e-06 0.0003 21.2 0.4 2 23 231 252 231 252 0.97

4 26 0.0084 0.78 10.5 0.3 3 23 260 280 258 280 0.96

5 26 6.8e-05 0.0064 17.0 0.9 2 23 291 312 291 312 0.98

6 26 7.5e-07 7e-05 23.2 1.1 1 23 333 355 333 355 0.99

7 26 2.9e-06 0.00027 21.3 0.8 1 20 361 380 361 383 0.95

8 26 2.8e-05 0.0026 18.3 0.7 1 23 389 412 389 412 0.95

9 26 0.0027 0.25 12.0 2.2 3 23 423 444 421 444 0.97

10 26 1.9e-06 0.00018 21.9 2.1 1 23 567 589 567 589 0.98

11 26 0.00032 0.03 14.9 3.3 1 23 595 617 595 617 0.99

12 26 0.049 4.6 8.1 1.6 1 23 623 645 623 645 0.97

13 26 0.0028 0.26 12.0 6.7 1 23 736 758 736 758 0.98

14 26 3.4e-05 0.0032 18.0 5.1 1 23 764 786 764 786 0.99

15 26 0.00027 0.025 15.2 1.0 3 23 794 814 792 814 0.97

16 26 0.00041 0.038 14.6 7.6 1 23 820 842 820 842 0.98

17 26 2.4 2.3e+02 2.7 1.3 2 23 1240 1261 1239 1261 0.94

18 26 0.00071 0.066 13.9 1.3 1 23 1267 1289 1267 1289 0.98

19 26 0.0071 0.67 10.7 1.6 1 23 1295 1317 1295 1317 0.98

20 26 1e-07 9.8e-06 25.9 1.4 2 23 1396 1417 1395 1417 0.98

21 26 0.00074 0.069 13.8 3.5 1 23 1423 1445 1423 1445 0.99

22 26 9.5e-05 0.0089 16.6 1.9 1 23 1451 1473 1451 1473 0.98

23 26 0.00039 0.036 14.7 2.5 1 23 1479 1501 1479 1501 0.98

24 26 9.1e-06 0.00086 19.8 0.4 2 23 1726 1747 1725 1747 0.97

25 26 1.4e-05 0.0013 19.3 4.5 1 23 1753 1775 1753 1775 0.98

26 26 2.7e-06 0.00026 21.4 1.1 1 23 1781 1804 1781 1804 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	26	0.0024	0.22	12.2	2.1	2	23	176	197	175	197	0.96
2	26	0.00011	0.0099	16.5	1.1	1	23	203	225	203	225	0.98
3	26	3.2e-06	0.0003	21.2	0.4	2	23	231	252	231	252	0.97
4	26	0.0084	0.78	10.5	0.3	3	23	260	280	258	280	0.96
5	26	6.8e-05	0.0064	17.0	0.9	2	23	291	312	291	312	0.98
6	26	7.5e-07	7e-05	23.2	1.1	1	23	333	355	333	355	0.99
7	26	2.9e-06	0.00027	21.3	0.8	1	20	361	380	361	383	0.95
8	26	2.8e-05	0.0026	18.3	0.7	1	23	389	412	389	412	0.95
9	26	0.0027	0.25	12.0	2.2	3	23	423	444	421	444	0.97
10	26	1.9e-06	0.00018	21.9	2.1	1	23	567	589	567	589	0.98
11	26	0.00032	0.03	14.9	3.3	1	23	595	617	595	617	0.99
12	26	0.049	4.6	8.1	1.6	1	23	623	645	623	645	0.97
13	26	0.0028	0.26	12.0	6.7	1	23	736	758	736	758	0.98
14	26	3.4e-05	0.0032	18.0	5.1	1	23	764	786	764	786	0.99
15	26	0.00027	0.025	15.2	1.0	3	23	794	814	792	814	0.97
16	26	0.00041	0.038	14.6	7.6	1	23	820	842	820	842	0.98
17	26	2.4	2.3e+02	2.7	1.3	2	23	1240	1261	1239	1261	0.94
18	26	0.00071	0.066	13.9	1.3	1	23	1267	1289	1267	1289	0.98
19	26	0.0071	0.67	10.7	1.6	1	23	1295	1317	1295	1317	0.98
20	26	1e-07	9.8e-06	25.9	1.4	2	23	1396	1417	1395	1417	0.98
21	26	0.00074	0.069	13.8	3.5	1	23	1423	1445	1423	1445	0.99
22	26	9.5e-05	0.0089	16.6	1.9	1	23	1451	1473	1451	1473	0.98
23	26	0.00039	0.036	14.7	2.5	1	23	1479	1501	1479	1501	0.98
24	26	9.1e-06	0.00086	19.8	0.4	2	23	1726	1747	1725	1747	0.97
25	26	1.4e-05	0.0013	19.3	4.5	1	23	1753	1775	1753	1775	0.98
26	26	2.7e-06	0.00026	21.4	1.1	1	23	1781	1804	1781	1804	0.97

Sequence Information

Coding Sequence: ATGTTGACGCGACACAGTGTAGTTACAGAATCTCCTTCACATGTCGATACAATACCTATAAATCTCGTTGCTACTGAGGATGGTCGAACGCTTCTAGCAGTAACTGAACATAAAGACGGTATGTTGGAAATTGTTGCAACTCCAGTTATGCTTGTTGGACAAAGCGAAGCTGCATCGCCACTAGTAGATGTAAAAAATTTTAATGGAAATCTAATATTACATTCGCCTGTTTTTCAAATAAGCGTTGAAAATATTGTCAATGAGTCAGAACTTCAGCAACCAACACAAAATTTTGAGACTGAGCCTAATAGCATTGATCAAATGAAGTTACAATCATGCAGAGAATTAACATGCAAGGAAACAGTTACACAAGAATATCAGTCTCTTTCTTCGAATGATTCAGTAGCTAGCGAAAAGGATGGAAAAATTTGTAAACAGAAGCCAATTAATACATCTGTGAAAAAAAATAGCCCTGGAAGGCCCAAAAAAAACAAAGCGATTTCTTTGCAAGATACAGATAGTCTAACATGCGACATTTGCCACCAAGAATTTGGTAAACAAACATTATATCGGAAACATATGGAAAATCATGCAGAAGAAAAACCACATCGATGTCCAAAATGTTCTGCATCGTTCAACGTGCCGACAAATTTTACACTTCACATGGCAACGCATAATACAGGTGAACCGAAATGTCCAGAATGTGGGAAAAAATTCGCGAGAATGGCTAGCTTAAAGTCTCATATGTTGTTACATGAAAAAGAAGAAAACTTATTCTGTACAGAATGCGAAGATGCTTTCTCGACAAAGACTCAATTAGATGCACATTTAAAGCTACATGGGGAAAAGTGGACGATTGAAGAAGTACGAAAGTGTAAATTATGTAACAAACAGTTCAGTCAACCCGCCTTATATAGACTTCATATTCGTGAGCACTATAGGTTGCAGACAAAAGTAGTAAAACAAACGAAAAGAGGGACAAAACACAAAACAATGTATAAGTGTACCATATGTTTGAAGTCTTTTCAAAAGCCAAGTCAATTGATGCGGCATATTAGAGTGCATACTGGCGAAAAGCCTTTCAAGTGTACAGACTGCGGTCGTGCATTCACGCAAAAGAGTTCGCTGCAAATTCATACGTGGCAACACAATGGTATTCGACCTCATGCTTGTGAGTTTTGCAATGCCAAGTTTAGTCAGAAAGGTAATTTGAATGCTCATATAATGAGAGTTCACAATGTCCCAGAGGGAGAACCTATATACGGATGTAATTATTGTTCATGCGTGTTTAAAAAACTCGGCAGTTTGAATGGTCACATGAAACGTATGCATACCGATGTAAACGAGGAGAATACCATTAATGACAATACTCATTCGAGTAATACCGTGGAGTCTGATATACGTGCAACAGTTGATAGTGTTATAACACAACTGGCATCTTTAGAATCCGACATTCATCAAACTACAGAATCGTCAAATATCGAACCGCGTTTATTATCGGAAAACGTAACGAAAAGGGATATTTTACAACAAGCGTTGAAAAACAGTGGTCTTCCTAGTAAAAATAAAATTGCTTCTGAAGAGATAAAGAAGTTTGGAGCTCGTGTTAATTTTGTAACATTATTGGATCGAGCGCCTGATGGTGATACGAGAAAATATTTGACAATAAAACAACGATGCGTAGGAAACATGAGATGGTACGCGTGTACATTTTGTCACAAAGAATTCAAAAAACCGTCAGATTTGATACGTCATTTGCGTGTTCATACGCAAGAAAAGCCTTTTAAGTGCACCCACTGTTATCGTTCGTTCGCTTTGAAATCTACTATGATAGCACACGAACGTACGCATTCAAGTGTTAAACGTTACGCTTGTGGTTCCTGCGAGAAAGCATTCGTGTGCCATAGTAGTTTAATTGCACATACTAGATTGCATGCAAAGTCCGAAAATTGTTCAAATAAAACCACTGACAATGATAAGGACCCCGACACATATGCAGTAATTGATGCTGACATTTATCCTACTGATCAATTGAAAAATCGAATAAAGGGTAAATTAAAATTATCACCGGAAGTAGAAAGTTTAGTACCTCAAGTTATCTTGCAAGAACCGTTGGTAATTAGTGATACAGGAAATAAAATTTCCGTGGTATCTTCGGGAAAGAAAAAACGTGCCTATGATACATCTACTGATCAGGCCAGACCCCATAAATGTTGGATTTGTCAGGCGGCATTTAGAAAAATCAGTCACTTGAAGCAACATCATCGCCGCCACACGGGAGAACGTCCATATAAATGCACAAAATGCGATAGGAGATTTACATCGAATAGTGTTCTAAAATCGCATTTGCATACTCACGAAGATTCGAGACCATACGGTTGTTCTCTTTGTAATGCGAAATTTTCTACACAAAGCAGCATGAAAAGACACTTGGTTACTCACAGTAATAAAAGACCGTTCATGTGCCCTTATTGTCACAAGACTTTCAAAACTTACGTCAATTGTCGGAAACACATGAAAATACATAAGCACGAATTGGCACAACGGCAATTGGAACAACAGAAAATCAGAATACAAGAACAAGCTTCAGACAAGTCAAATATGAAGGAAAGTTCTAAACAAGAAGCGGCTCTTGAATCGTCTTCCTCCTCTTCTGCCTCTATCACTACTATTAATTCCACTATTACCAGCAACATCTCCATCACTACCACTGCCACTACCAGTACCACCCCTACCACCGTCACAACTTCCTCTTCTACGTTTTCAGATAATCTTGCACTTTCTCGTCTTGGATCGGTTGAATTGTCATTTCAATCACAGCTCGGATCAGAGCTTTCACAAGCTTTTCCCGAGTTTCAAAATATAACTGAAGGAAAGGAAAAAATAAGACCAGTTTTAGCAACAAATTGCGATACTACAACGTTTATTAATCAAAATGTAGCGGGAATAGCTGTAACAAATCTTGAAAATTCACCAATATTACAAGCTGATGAAGCTGGTTCAGTCACGTTGCCCGTTTACTCTGGCGATCAGACACTTACACCGGAAAGTATACGAGAAATAGAAGAAACTTTGAATCAACAGTTTTTTAATATCGGGATGAATCTTAACTTGGGAGGTAATCACTCGAGACATTCGAGTAGTACAAACACGAGTGATTTTAGTCATATGAAAGAACAACAGCAACCTGTATTGAATGTTATATATGAAAATAACAATAACAGTAACTGTAATAGTAACGTAGAATCAGCTGGAGAACATGTGTTTTCGACGCAATTAGATTCATTTGAGATGGACCATATTACTTTGCAATCGGATACTGAAATTGACATTGGACTAGATACAAGAAATTCGACTAGTATGGCGAGTATACTACCTAGGAATGTAAAAGATGAACATCGTCTTTCTGTTTGTGTTACGACGCCAGATAACATAAATGTTGAACAATCAGAAAAGTCTGGTGTGCAAGCGGTTGTATTTGTTTCCCAGCCAAACTTCTCCAAAAAAGAGAATATAACAAGTGAATTTACTGTAGAAGAAACCCAGAAGAACAGTATTCAGAAACAATGTATAATCAACCCGATATTCTTTACAGAAGACTTTCGGGGAACATCACAAGATTTCAAGATTCAATCAAATATGCACGCTTTGTCATCCGATGTTCCAGAAATCGTTAAAACCGCTACGGGCAAAATATCCCGTGGACAATCTCTATTACAGTGTCATATGTGTAGCCAACAAGGATTCACGACAGTTGGTTTAAAGGAACATTTGACAAGCCATCGCGGAACGAAGGAATATCAGTGCACAGAGTGCTCTTCTAAATTTTACACAAATGGTGGATTAAATAGACATTCGAAGATTCATGTCGTCAAGCAACCATTTAAATGTTTATCGTGTGAGAAGCAGTTTAACAATAGGATCCAATTGCTATCACATAGTAAAATTCATGAAACTTCAGTATGGAATGCTTCAGAGATAAATGATAATTCAGATAATTCGACGTTTTTATCGGAAGTGCAACAACCACGGATTGCAAATGATCATTCACCATTACATAATATTATGATAGAACCCGATTCTGCCGTTTCTGAGAAAGTTCTGTTGGATACAGTAGCTGAAAAAGAAGTAATGGATCAAGTAGAAATTTTGCTGGAAAAGAAGGAACGAAAAGAGTATACAAACAAATGTAAATATTGTCCGAAAACTTTTCGCAAACCGAGTGATCTTATAAGACATGTACGCACGCACACAGGAGAACGACCATACAAGTGCGATTATTGCAGTAAAAGTTTTGCCGTAAAATGTACTTTGGATTCTCATACAAAAGTTCATACGGGAAAAAAGACATTTCGCTGCCATGTGTGCAATAGTTTATTTGCGACTAAAGGTAGCTTGAAAGTTCACATGCGTTTACATACCGGTTCGAAACCATTTAGATGTCCTATATGCGATTCGAGATTTCGAACATCCGGCCATAGGAAAGTACACTTATTGAAACATGCACGCGAACACAAAGATAATCCAAAGAGAAAACAAAAACATTTGAAGGTTGCAGTCATAGCTGAAGTAGCGACTGATCTTGAGAAATGTGACGGAAAGGAAGAGAAAATGAATAATTTTGAGCCAAAACAGCAAATAGCACAGGAACAGCAGTTATCACAGGCGGTTGCAGGATTAACATCCCATTTAGAGGCATATAGTATTGAAACAGCTGCTTCCTGTTTATCTGATCAAATTAATTTCGACACAGAAGGTATCGTATCGAACAACAATCAAACGATTGTGTCCATAAACGAAAACAATCAGTTAGTTACGAATTTACACTTTCTTCTGACAAATGGTCTTGTTACTATACAAACCGAAGAATCGTTGTTGTCACAATCATCTGCATCACCAGCTAACAATTCGCAACATCGGCCAGCTGGGGTTCCCGATACTGGGTGTGCACTAACAACACCCAGCGTCGTATCTGATACTAACGAACAACATGCCAAGGATGAAATTCATATAGAACAAATGTTAAAAACGCCAGCAAATAATTGTCTTTTAGCGATATCAACTGTGACACCTTCATTGGAACGACAGCTGGAACCATTTTCAAAGGTGACTACGGAAGAAACGTTACCAGTAGTAGCCAATAAACCGACGATCAAAGGGAATCCATCGAAAAAGGAATGCGACATTTGTGGGAAAATATTTACAAAACCGTATCAAGTCGAAAGACATAAACGAATTCATACGGGTGAACGGCCATACAAGTGTGATCTATGTACGAAATCATTTGCCCAAAAGTCAACTCTACAGATGCATCAAAAACACCACACTGGCGATCGACCCTACGCTTGTTCGTACTGTGAATATTCTTTTACGCAAAAGGGCAATCTTCGAACACATGTTAAACGCGTACATCAACTGGATACTGTCGACATCAGAAAATGGAAACGTAACCGTCAATCCTTCCTACCCAAAACATCTCTTCAGGAAAACACGATCGAAGCTAAGAGTCTAAATTTAGACAACATATCGTTTGTAGAGCTGCTTAAATAG
Protein Sequence: MLTRHSVVTESPSHVDTIPINLVATEDGRTLLAVTEHKDGMLEIVATPVMLVGQSEAASPLVDVKNFNGNLILHSPVFQISVENIVNESELQQPTQNFETEPNSIDQMKLQSCRELTCKETVTQEYQSLSSNDSVASEKDGKICKQKPINTSVKKNSPGRPKKNKAISLQDTDSLTCDICHQEFGKQTLYRKHMENHAEEKPHRCPKCSASFNVPTNFTLHMATHNTGEPKCPECGKKFARMASLKSHMLLHEKEENLFCTECEDAFSTKTQLDAHLKLHGEKWTIEEVRKCKLCNKQFSQPALYRLHIREHYRLQTKVVKQTKRGTKHKTMYKCTICLKSFQKPSQLMRHIRVHTGEKPFKCTDCGRAFTQKSSLQIHTWQHNGIRPHACEFCNAKFSQKGNLNAHIMRVHNVPEGEPIYGCNYCSCVFKKLGSLNGHMKRMHTDVNEENTINDNTHSSNTVESDIRATVDSVITQLASLESDIHQTTESSNIEPRLLSENVTKRDILQQALKNSGLPSKNKIASEEIKKFGARVNFVTLLDRAPDGDTRKYLTIKQRCVGNMRWYACTFCHKEFKKPSDLIRHLRVHTQEKPFKCTHCYRSFALKSTMIAHERTHSSVKRYACGSCEKAFVCHSSLIAHTRLHAKSENCSNKTTDNDKDPDTYAVIDADIYPTDQLKNRIKGKLKLSPEVESLVPQVILQEPLVISDTGNKISVVSSGKKKRAYDTSTDQARPHKCWICQAAFRKISHLKQHHRRHTGERPYKCTKCDRRFTSNSVLKSHLHTHEDSRPYGCSLCNAKFSTQSSMKRHLVTHSNKRPFMCPYCHKTFKTYVNCRKHMKIHKHELAQRQLEQQKIRIQEQASDKSNMKESSKQEAALESSSSSSASITTINSTITSNISITTTATTSTTPTTVTTSSSTFSDNLALSRLGSVELSFQSQLGSELSQAFPEFQNITEGKEKIRPVLATNCDTTTFINQNVAGIAVTNLENSPILQADEAGSVTLPVYSGDQTLTPESIREIEETLNQQFFNIGMNLNLGGNHSRHSSSTNTSDFSHMKEQQQPVLNVIYENNNNSNCNSNVESAGEHVFSTQLDSFEMDHITLQSDTEIDIGLDTRNSTSMASILPRNVKDEHRLSVCVTTPDNINVEQSEKSGVQAVVFVSQPNFSKKENITSEFTVEETQKNSIQKQCIINPIFFTEDFRGTSQDFKIQSNMHALSSDVPEIVKTATGKISRGQSLLQCHMCSQQGFTTVGLKEHLTSHRGTKEYQCTECSSKFYTNGGLNRHSKIHVVKQPFKCLSCEKQFNNRIQLLSHSKIHETSVWNASEINDNSDNSTFLSEVQQPRIANDHSPLHNIMIEPDSAVSEKVLLDTVAEKEVMDQVEILLEKKERKEYTNKCKYCPKTFRKPSDLIRHVRTHTGERPYKCDYCSKSFAVKCTLDSHTKVHTGKKTFRCHVCNSLFATKGSLKVHMRLHTGSKPFRCPICDSRFRTSGHRKVHLLKHAREHKDNPKRKQKHLKVAVIAEVATDLEKCDGKEEKMNNFEPKQQIAQEQQLSQAVAGLTSHLEAYSIETAASCLSDQINFDTEGIVSNNNQTIVSINENNQLVTNLHFLLTNGLVTIQTEESLLSQSSASPANNSQHRPAGVPDTGCALTTPSVVSDTNEQHAKDEIHIEQMLKTPANNCLLAISTVTPSLERQLEPFSKVTTEETLPVVANKPTIKGNPSKKECDICGKIFTKPYQVERHKRIHTGERPYKCDLCTKSFAQKSTLQMHQKHHTGDRPYACSYCEYSFTQKGNLRTHVKRVHQLDTVDIRKWKRNRQSFLPKTSLQENTIEAKSLNLDNISFVELLK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00215155;
90% Identity: iTF_00217878;
80% Identity: -