Bdif013932.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus difficillimus
Gene Symbol
br
Assembly
GCA_014737525.1
Location
JACXIT010000176.1:3458091-3468848[+]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 1.1e-29 3.3e-27 95.0 0.1 1 103 22 120 22 125 0.95

Sequence Information

Coding Sequence
ATGGTAGATACGCAACACTTTTGTCTGCGATGGAACAATTACCAAAGCAGTATAACGTCGGCGTTTGAAAACTTAAGGGACGATGAAGATTTTGTGGACGTCACATTGGCCTGCGATGGCAAAAGCCTCAAAGCGCACCGCGTCGTACTTTCCGCATGCAGTCCCTATTTTAGAGAATTGCTCAAGAGCACACCGTGTAAACACCCGGTGATAGTACTTCAAGACGTAGCGTTCAGCGACTTGCACGCTTTGGTGGAGTTCATCTATCACGGGGAAGTGAACGTGCATCAGCGTTCCCTTAGCAGTTTCTTGAAGACTGCCGAAGTCCTCAGGGTATCGGGACTTACGCAACAGGCCGACCAAACAGACAGGGACGAGCTATCCCATGTACGCGCGTTGGCTGCCGGTGGTAACCACCTTCCCTTTCACGAAAAATCAGAAGAGAGTTTCCCCCGGGGTGGTTCCCCGCCCACGCCAGTAACCCCGACACCGACGACCGTGCAGCAATTGCTACGCCGAGCGCAGATACGCAGGAACGAGAGACGAACACCGGATCCGCACGATGAGTCGGCGAAGAAGCCGAGGGTGCCGTCGCCGCCTCTCAACAACAACGACGCTACTCCCACGGATTTCTCGATGGTGAAGAACAACCATCTGTCGAGCAAGGTCGAGGGTAACGGCGTGCACGAGGAGAACAGCCCCCTGGAAGACAACATCAAGTGCGAGCCGTTGGAGCTGACAGGTGGTAACAGCGGCAACGGAGGCAACAACGAAGACTCGTCGGATTCTGGAGCTGCGGCGTCGGACCGGCCACCCGCGTCGGCCAGCAGTAACGAGCACGAGGCCGAATCCGAACACACGTCCACCCCGAATTTTTTGTCCGAAACGAAAATCTTCCCCACGCCTGGAAGCTTTAATTTCAGTATGGCGGCGCTAGCCACGGAGCATACACCATTGTCAGTGAAATTTCCAGGATTGGGCCACGGGTTGCAACCACCGGACTTGGCAGGAACTTCGCAAGACCGGGAGGTCGCCGAGGAGGACGGGGGTTGGCAGTCCGCTACCAACGGAGACGGTCAACGGCTAACCGGCCAATCGAGCCAAAGTACGGCAACTAGTCAGTGCGAGATGATGCAGGGGCACCAGCAGCATCAGGAGCTGCCCATTATCGATCTCTTAGACGACATTAACGATCAGATGCAGATCGTGCTCAAGTCGGAACCTCTGTCGCCGAAGATAGACGAGCTCGAGTCCTGTCTGCTCAACGAGCAGATCGATCTGCAATCGGATCGAGGCTCGGCCAACAATGCTAATGGTCAGCAGACGCGTCAGCAGAATGGTAACAATAACAACAACAACAGCAACAATAACAACAGGCAACACCAGCAACCAAGGACGACGTTGAACGAAACTGTCCCGTTTGCCGATCTTCGTTGGTTAACGCAGAATGGTAACATGCAACCGGCGTCGAAAGTTCGCGACGCCTCCAGAACTCAGATCGAGCAGGAACTTAAATACTCGAGCCGCTCGATCACCGGCACTTACTGTAGCTTCTGCCAGAAGACTTTCTCTCGTGCGTGGTCTCTTCAGAGGCACTTGGCGGACACGCATTTTTACGTACCGCAGTCGCTCTCCTGCGACCAATGCGGTAGAAGCTACAAGTCGAGGAACAGTCTGGTCAGTCACAAGAGCCAGTACCACGCGAGAAAAGAGCGAAAGGAACACGAGGAACAATGCGAGGTCACGTATTGA
Protein Sequence
MVDTQHFCLRWNNYQSSITSAFENLRDDEDFVDVTLACDGKSLKAHRVVLSACSPYFRELLKSTPCKHPVIVLQDVAFSDLHALVEFIYHGEVNVHQRSLSSFLKTAEVLRVSGLTQQADQTDRDELSHVRALAAGGNHLPFHEKSEESFPRGGSPPTPVTPTPTTVQQLLRRAQIRRNERRTPDPHDESAKKPRVPSPPLNNNDATPTDFSMVKNNHLSSKVEGNGVHEENSPLEDNIKCEPLELTGGNSGNGGNNEDSSDSGAAASDRPPASASSNEHEAESEHTSTPNFLSETKIFPTPGSFNFSMAALATEHTPLSVKFPGLGHGLQPPDLAGTSQDREVAEEDGGWQSATNGDGQRLTGQSSQSTATSQCEMMQGHQQHQELPIIDLLDDINDQMQIVLKSEPLSPKIDELESCLLNEQIDLQSDRGSANNANGQQTRQQNGNNNNNNSNNNNRQHQQPRTTLNETVPFADLRWLTQNGNMQPASKVRDASRTQIEQELKYSSRSITGTYCSFCQKTFSRAWSLQRHLADTHFYVPQSLSCDQCGRSYKSRNSLVSHKSQYHARKERKEHEEQCEVTY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00219441; iTF_01454273; iTF_00214466; iTF_00232674; iTF_00225316; iTF_00232264; iTF_00214665; iTF_00232878; iTF_00225557; iTF_00232059; iTF_00084643; iTF_00087277; iTF_00089198; iTF_00085808; iTF_00088432; iTF_00087569; iTF_00085490; iTF_00088915; iTF_00088123; iTF_00086398; iTF_00084927; iTF_00086751; iTF_00360293; iTF_00360559; iTF_00360984; iTF_00361248; iTF_00966310; iTF_00184016; iTF_00966097; iTF_00184242; iTF_00183360; iTF_00183591; iTF_00625579; iTF_00625798; iTF_01123140; iTF_01122731; iTF_01123325; iTF_01122526; iTF_00964556; iTF_00964770; iTF_00866093; iTF_00866348; iTF_00763310; iTF_00763534; iTF_00864057; iTF_00864284; iTF_00773902; iTF_01424688; iTF_01424455; iTF_01539952; iTF_01539687; iTF_00141489; iTF_00141327; iTF_00963922; iTF_00964132; iTF_00230357; iTF_00233550; iTF_00233307; iTF_00230108; iTF_00219875; iTF_00230759; iTF_00230959; iTF_00221584; iTF_00220120; iTF_00221340; iTF_00118088; iTF_00118340; iTF_00223272; iTF_00223522; iTF_00224201; iTF_00228302; iTF_00228047; iTF_00223956; iTF_01069994; iTF_01067019; iTF_01069292; iTF_01067247; iTF_01068624; iTF_01069745; iTF_01065650; iTF_01068374; iTF_01065886; iTF_01069054; iTF_00228752; iTF_00228998; iTF_00226674; iTF_00226920; iTF_00222835; iTF_00222602; iTF_00220661; iTF_00220903; iTF_00229429; iTF_00229670; iTF_00224630; iTF_00224883; iTF_00227351; iTF_00227595; iTF_00676345; iTF_00676102; iTF_00761050; iTF_00761265; iTF_00231643; iTF_00231393; iTF_00217150; iTF_00217396; iTF_00216031; iTF_00215784; iTF_00217824; iTF_00218054; iTF_00218752; iTF_00218504; iTF_00864725; iTF_00864969; iTF_00983671; iTF_00983876; iTF_00633720; iTF_00633957; iTF_00391415; iTF_00963512; iTF_00963273; iTF_00024698; iTF_00024921; iTF_00216474; iTF_00216719; iTF_00306362; iTF_00306608; iTF_00215101; iTF_00215343; iTF_00226238; iTF_00225994; iTF_00862911; iTF_00862658; iTF_01498527; iTF_01498294;
90% Identity
iTF_00219875;
80% Identity
iTF_00219441;