Bcul010975.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus cullumanus
Gene Symbol
BTBD7
Assembly
GCA_014737535.1
Location
JACXIX010000037.1:799746-804566[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 3 7e-14 2.1e-11 44.0 0.0 4 87 162 245 159 269 0.80
2 3 1.8e-06 0.00056 20.1 0.0 22 49 302 330 298 372 0.71
3 3 0.53 1.6e+02 2.5 0.0 71 107 391 428 380 431 0.88

Sequence Information

Coding Sequence
ATGAATGTATTCCGAATTTTGACACCGTGTGTATTGCAACGTAGACGACCAAAGGAGGTTGATAATTCCGATAAAAGGGATTGCTGGTTCGTGAAAAGACGGCGTGGAGATGCTTCCTACATGATACATAGAATGGGTGCTTCTGCATCGTCAAGCATTACCAGTGTAGGTGGAGATTCGGTCCAAGCAGCTAGACTTTCATCCTCTGGTAATCCACCTGATCAACATGGCATTGCTATCAGGGAAAAGAAGAAGAAAATGACGGGGTTCGCGACTTTACGGAAGAAGTTCATTCGAAGACGTCGGTCTTCAAAGGCCTGCGACCATGGTAGGATAATCCGAGATTTGGTCTCAACATGGAGCCATTTAGAGGCAACGGCGCTTTTGGAGGAGTACGAGGCGTTGGCTGCATTAAAGGATCTCCATGTTCAAGCCGAATTAGCTAGACCACCGGCTGCCACATACAAACAGGATTTGTCGATGTTGTACGACTATAAACATTGTTCTGATGTGGATTTCGTCTACCGAGGAGCATGCTTCCCTGTTCACAGAGCCCTGTTGTCAGCCCGTTGTCCCTACTTTAGGGATTTGCTGGCTGGATGCCCGGGATACGGTGCTAGAATATGTTTGGAGCTGAGAACACCGAATCTCGAAGTACAAATGTTTTCAGCATTATTGCGATATCTCTACACTGGTGATATTTGTCCACATGATGCAGCTCTGGAGGCGAATCTCTTACGACGACTGAGCGAAGAATTCGGCACACCGAATCCGCTGGAACACGATCTCAGATACCTGCTGGACACCGGTGATTACGCGGACGCTGCGTTAGTGTTCACATCGGACAGTGATTACCAGAGACCAGATAGTGGAAGTTCAGAATATGGATTCCGGCCAAAGTTAGAACTGCCATGTCATAAAGCGATACTTTCTGCGAGATCCCCGTTCTTCAGAAACTTAATACAAAGACGGACTAGATCTGGGGAAGATCACACAGAAAGAGCGCTTCATATACCTACTAGAATAGTTTTGGATGAGAGTGTAATACCCAAACGATACGCCAGAGTATTGTTACATGCAGTGTATTTAGATACAGTTGATTTATCGTTAATTATGAGAGGTAATGGTTGCGGGAACAGCGCTGGTAGTCTTGGAGAGGTTCAGGCTCTTACTCATACTGGACGTGTTCGACCAAGTCCCTTAGAAGAAGCGATGGAATTGTACCAAATCGGCAGATTTTTGGAACTAGATATATTGTCACAGGGTTGTGAAGATCTTATTTTAGAATACCTTACATTGGAATCGCTCCCAACTGTTTTGAAGTGGGGCAGTCAACCTCACGGATCGGCATGGGTACATAGACAAGCCTTGCATTATTTAAGAGAGGAATTCCAGCCGGTCGCTTCTTCTTCTATTCTTCACCAATTGGACCACGTACATTTGGCGAACGTTTTGCAAAGTCATTTCTTGCAAGCGAGCGAACTTGAAATACTGCAGGCGGTACTCAAGTGGGGGGAACAAGAATTGGTGCGTCGTATGGAAGATCGGGAACCAAATTTGCTCAGTCATACGGTGCACTCTGTGACAAGAAAGGGGTTGAAGAAAAGGGATTTAAGCGATATAGAGTTGCGAGAGATACTTAGTGAGCTTCTACCACTTGTCAGAATGGATCACATATTACCCCCAAATAGTGAAGCGCTGGCTCAAGCTATTAGAAGAGGATTAGTTTCAACTCCACCGAGTCATATGATAGGAGACGAGAGGGAGAATTTACGAATGAATGCATGGATAAGGGGAGGGAAGAAAAATGGATTTTTTGTAAGGCCACGTCTGTTCATGCCTTATTACGAGGAAATAAAGTCTTTAGTTGAGGAACAAATAGTCCAAGAAGCAGATTTAGTGAGATTGCGAAGGCCACGGTATGTGGCCGATATTCCCGATGCCTTGTACATGGTTGATGAGAAACCAAGACCAATGGGTACAGCCGGGGTGGATGTTCTCGCCGCGGCGTTTCCAGTTCCAGATTCTGCGACCTTGGCAGCTATGCTGAAGCGAGAGCAGAAATTGAGGCAGTCTCCCAGTTGTCAGAGGGCTATCAGTTTGCCCCTCTCATCGCGACACGAAATTAATAGGCAAGTGCGACTACGTGTTGTGAGGGAGTTCAACCTACCTGACACGGTGGCGGATCTGTTAGAAGTGAGTACTTTTCTCCTCCTGTTAGAGGAGAATAATTCTAAAGTCACCTGTACAAACAATTTTAGGATATTTTGA
Protein Sequence
MNVFRILTPCVLQRRRPKEVDNSDKRDCWFVKRRRGDASYMIHRMGASASSSITSVGGDSVQAARLSSSGNPPDQHGIAIREKKKKMTGFATLRKKFIRRRRSSKACDHGRIIRDLVSTWSHLEATALLEEYEALAALKDLHVQAELARPPAATYKQDLSMLYDYKHCSDVDFVYRGACFPVHRALLSARCPYFRDLLAGCPGYGARICLELRTPNLEVQMFSALLRYLYTGDICPHDAALEANLLRRLSEEFGTPNPLEHDLRYLLDTGDYADAALVFTSDSDYQRPDSGSSEYGFRPKLELPCHKAILSARSPFFRNLIQRRTRSGEDHTERALHIPTRIVLDESVIPKRYARVLLHAVYLDTVDLSLIMRGNGCGNSAGSLGEVQALTHTGRVRPSPLEEAMELYQIGRFLELDILSQGCEDLILEYLTLESLPTVLKWGSQPHGSAWVHRQALHYLREEFQPVASSSILHQLDHVHLANVLQSHFLQASELEILQAVLKWGEQELVRRMEDREPNLLSHTVHSVTRKGLKKRDLSDIELREILSELLPLVRMDHILPPNSEALAQAIRRGLVSTPPSHMIGDERENLRMNAWIRGGKKNGFFVRPRLFMPYYEEIKSLVEEQIVQEADLVRLRRPRYVADIPDALYMVDEKPRPMGTAGVDVLAAAFPVPDSATLAAMLKREQKLRQSPSCQRAISLPLSSRHEINRQVRLRVVREFNLPDTVADLLEVSTFLLLLEENNSKVTCTNNFRIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01234456;
90% Identity
iTF_00676129; iTF_00770498; iTF_01066371; iTF_00118116; iTF_01424484; iTF_00218533; iTF_01539717; iTF_00223303; iTF_01067048; iTF_01067721; iTF_01070474; iTF_00228077; iTF_01199533; iTF_00303214; iTF_00228783; iTF_00220689; iTF_01418449; iTF_01065682; iTF_00223987; iTF_01069779; iTF_00140692; iTF_00219221; iTF_01068405; iTF_00217180; iTF_01069084; iTF_00980299; iTF_00252204; iTF_00297698; iTF_00295395; iTF_01473315; iTF_00254470; iTF_00293862; iTF_00293095; iTF_00296935; iTF_01130953; iTF_01475593; iTF_00255212; iTF_00253713; iTF_01474833; iTF_00252950; iTF_01474072; iTF_00298460; iTF_00291677; iTF_00294623; iTF_00296160; iTF_01523500; iTF_01198799; iTF_00016147; iTF_00086429; iTF_00084673; iTF_00087308; iTF_00085520; iTF_00088947; iTF_00088154; iTF_00014848; iTF_00142561; iTF_00225345; iTF_00230786; iTF_00684266; iTF_00684879; iTF_00229458; iTF_00227382; iTF_00232087; iTF_00222008; iTF_00233336; iTF_00216505; iTF_00230137; iTF_00215131; iTF_00221371; iTF_00214494; iTF_00219904; iTF_00231424; iTF_00232704; iTF_01071108; iTF_00966119; iTF_00762657; iTF_01169281; iTF_00866116; iTF_00763334; iTF_00184040; iTF_00864746; iTF_00863371; iTF_00024717; iTF_00864078; iTF_00861999; iTF_00866802; iTF_00391443; iTF_00306388; iTF_00633749; iTF_00183386; iTF_00862682; iTF_00865434; iTF_00860509; iTF_00360318; iTF_00861280; iTF_01422342; iTF_01423784; iTF_00873895; iTF_01419738; iTF_01421028; iTF_01420365; iTF_01417811; iTF_01419097; iTF_00141929; iTF_00625610; iTF_00361009; iTF_00224660; iTF_00761081; iTF_00734042; iTF_01123164; iTF_00963946; iTF_00963300; iTF_00964582; iTF_00961934; iTF_00962616; iTF_01122558; iTF_00983070; iTF_00982392;
80% Identity
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