Bcon000184.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus confusus
Gene Symbol
Mtf1
Assembly
GCA_014737475.1
Location
JACXIV010000095.1:330511-334393[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 3.2e-06 0.00025 21.1 0.8 1 23 125 149 125 149 0.98
2 6 0.00024 0.018 15.3 0.2 1 23 155 179 155 179 0.95
3 6 0.0002 0.016 15.5 2.2 1 23 185 209 185 209 0.97
4 6 3.1e-06 0.00024 21.2 0.7 1 23 214 238 214 238 0.97
5 6 3.3e-05 0.0026 17.9 5.1 1 23 244 268 244 268 0.98
6 6 4.8e-06 0.00037 20.6 2.5 1 23 274 298 274 298 0.98

Sequence Information

Coding Sequence
ATGGCGGCGTGGGAAGGCGAAAAATTTCAAGAAATCGGGAATGCCGATGATATCGAAGAGAACTTCAATAACATTCTCGTGACGCATGATCTTCAGGATTGTCTGGATGATAGTTTAGATTTAACCAGTTTTGGGAAAGTGTATGAAGAAAGTGCTGTGTTTGATTACGAGAAGTATTCCGATGACGATGCTCCTCTAGACGAAAAACTATCAAATGATAATGTTACCGAGTCAATACATTCAATCAACCCCCATGAAATTTATATGCGCATCCATTCTGGCCGAGATGACATTTCAACAATTAAATCTTCACATACAACTACTGCAATTCAAAGCATAGTTCCAGATACAAATCAGAAACATATTGGTCGATATACCTGTGAATATGAAGGTTGTAATAGGACATATAGTACAGTTGGTAACCTACGTACCCATATGAAAACACATAAAGGCGAGTATCGATTTAAATGTGCAGAACCAAGTTGTGGAAAGGCATTTCTTACGTCGTACAGCCTTAAGATTCATATTAGGGTACACACAAAAGTGAAACCATTTGAATGCAACCACAAAGGCTGTGAAAAAGCATTCAATACCCTTTACAGACTGAGAGCTCACCAAAGACTTCACAGTGGCAACACATTTAATTGCGAAGAGATTGGATGTGTTAAATTCTTCACTACTCTAAGTGATCTCAAGAAACATATACGTACTCATACTCAAGAAAGACCTTACAAATGTAGGGAAAAAGGATGTGGTAAGGCTTTTACAGCATCACATCATTTGAAAACGCACAGAAGAACACATACGGGAGAACGACCTTATGTATGTACTGTAGGCAATTGCAAACGATCCTTTACCACACCTCATAGTTTAAAGAGTCACTTGAAAACTCATAAGAGAACGACTGATATCGACGAAACGAAACATGAAGTCAATAAAGATGATTACAGAAACCAAAGAAACAGTGAGATATTGAAAACAGAAATCGATGTTGAAATAACGTCGAGAAATACAAATGTGCCATGTTATGCCATTATACCGTTATCTTCTAGCAATACACAAAATAAGGAAAGTATTACTTATTTATCTATTGAAAATCCAAATGATCAGTCATCTTCTACAAATGATATGATAGATATCTTAAATCAAAACAGACTAACCAAAGAACTTGATTATAACATCACTAACAAAGATGCTGAAAATTTAAATAAATCAACAAATGTCACTGTTCTTGCGTCGGAAAATATTGTCTTAGATAATTTTACCGAGCATACAATTGATAATTTTAATAATAATGAAAGTTATGACAAATTTAAAATATTCAATGAAGTAAATAATTCGAATTTACAACGGGATCAAAATCAACAATATAGTTCTAATCCTTCAACAAAAGTGCAAGATAGCAAGATTAATAATACAAGTAAGTCCAATTCAATAAATTTGGAGCAAAAAATTATACAAGACGGCCTACAAAATACAATTGTTCACATCTCGGAAGGGACGAATTTTACAAGTGATGTACAACAGTATGTAAATGATAATACTATTGCTAAAAAAGTTTATGATAATAGAACAAATGTAAGTGCAGTTGCTGAAAATAATAATGCGACTTTGTATGACACAAATTCTGTTACTAGTCATGTATCAAATATAATTAGTTCCTCTAGTGAGACTCAACTCTTTGATAGTGAGATAGGAAATTTACCATTTATTAATGATAGTTTACGAACTGGATCTCTTAATGAAGTTGAACATGCATTGAATTGTAATGTTATTGCAACTACGCAGTCAGAAGCTATTGAACTAGCCATAGCATCTGAGGAGGAAATACCTTCTCCTTGGATAGATGTCATGGCATTGGCAACCCCATCTGCTTTAAGGCGGCAGTCTTGGTCGGAATTGAACGCTTTTCCAACAGCGGTTCACTCATTAGTCGACTTAGTTGAACCGGAACCATATCCTTTACAGATAGAAAATGACATGCAACCATTACAAGTAAATAATGTAAATTTAGTAGACGTGGAAAACATTAATACCGAATGTACCGAAGTCACATGTTGTAAAGAGAACGATAAAGATAAAGAAAGCGAAAGCAGAATAAAAATAAAAAAAAATAGAAATATCCTACAGGAGATTACAGCCGAAGCAGATATATGCAAATGTATTGATTGTAAATGTGATCATCTACAAAATTGTCAAAATTGCTCAAACAATACAATTCCTGAAATTAATAAGAAGCACGTTTCATCGAAAATGGTAGATGATTTTGTATCTTGTTTACAAAGCGAATGTGTTTGCGACAATGAGCCCGGTGGCTGTGGGTCTTGTTGTGTTGTGATTTGTTTAAAAACATTGCAGCAATTGCAAAAAGTATTCAGTCGTAATTGCTGTAAAAGTACTAACAGTGTCACATGTTGTAGAGAAAAATTATTATCCCCATTAATGAAGTGCCAGTTAACAAAAAACCAATGA
Protein Sequence
MAAWEGEKFQEIGNADDIEENFNNILVTHDLQDCLDDSLDLTSFGKVYEESAVFDYEKYSDDDAPLDEKLSNDNVTESIHSINPHEIYMRIHSGRDDISTIKSSHTTTAIQSIVPDTNQKHIGRYTCEYEGCNRTYSTVGNLRTHMKTHKGEYRFKCAEPSCGKAFLTSYSLKIHIRVHTKVKPFECNHKGCEKAFNTLYRLRAHQRLHSGNTFNCEEIGCVKFFTTLSDLKKHIRTHTQERPYKCREKGCGKAFTASHHLKTHRRTHTGERPYVCTVGNCKRSFTTPHSLKSHLKTHKRTTDIDETKHEVNKDDYRNQRNSEILKTEIDVEITSRNTNVPCYAIIPLSSSNTQNKESITYLSIENPNDQSSSTNDMIDILNQNRLTKELDYNITNKDAENLNKSTNVTVLASENIVLDNFTEHTIDNFNNNESYDKFKIFNEVNNSNLQRDQNQQYSSNPSTKVQDSKINNTSKSNSINLEQKIIQDGLQNTIVHISEGTNFTSDVQQYVNDNTIAKKVYDNRTNVSAVAENNNATLYDTNSVTSHVSNIISSSSETQLFDSEIGNLPFINDSLRTGSLNEVEHALNCNVIATTQSEAIELAIASEEEIPSPWIDVMALATPSALRRQSWSELNAFPTAVHSLVDLVEPEPYPLQIENDMQPLQVNNVNLVDVENINTECTEVTCCKENDKDKESESRIKIKKNRNILQEITAEADICKCIDCKCDHLQNCQNCSNNTIPEINKKHVSSKMVDDFVSCLQSECVCDNEPGGCGSCCVVICLKTLQQLQKVFSRNCCKSTNSVTCCREKLLSPLMKCQLTKNQ