Beup006482.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Boloria euphrosyne
Gene Symbol
bab1
Assembly
GCA_951802675.2
Location
OX637875.1:6861297-6862784[-]

Transcription Factor Domain

TF Family
BTB
Domain
zf-C2H2|ZBTB
PFAM
PF00651
TF Group
Zinc-Coordinating Group
Description
The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 7.1e-24 3.2e-21 76.4 0.1 4 103 28 124 25 127 0.92

Sequence Information

Coding Sequence
ATGGGGAGCAGCGAAGGTCAGCAAACCTTTTGCTTAAAATGGAATCATCATAAAACCAATCTAGTGGAAATTTTAGAGGCTTTAATTAAAGTCGAGACGTACGTCGACTGCACACTTGTCGTCGATGACCAAGTGACCTTTAAAGCGCATAGGGTAGTACTTGCTGCAAATTCACCATACTTTCAATCAATATTAGCAGATGTACCTATGGATCATTGCAGTATACTGTTCCCAGGAGTTAAAGACTTCGAAATGCGTGCTCTCCTGGAATATATGTACACGGGTGAAGTTAATGTCACTCAAGCGCATATTCCTCGTATCATGAAGGTTGCGGAACAACTCGAGGTAAAGGGTTTGTTTGATATGACAGAACTACGGCGTCGACCTGGGAGTAGTGAACGCACTCCTGCGGCTTCTCCTCCGCGCGTGGTCCCCGCTGCGCCATCTAGCGTGTCACCTCCCATGGCGACTACTCGGTGGCCACTTGCACCTTCTGCACCCGTACTTTCAGCCGCCTACGATTCGGCGGACATGAACCCGTTAAAACGTAAAAAGCTATCTAGTATGTTAGCTACTCGTGACACCCCAATACTAAGGAACGTTCTCGCTCAAGCTACTCCAGTGGATTCATCTCAGCCTATTTCGCTTGTGTGTCACCCCGTTAGTCAGCATGATTCAACACGTTTACATTCTAACGGGTCGGCACATGAATCTGAAAGACCTGCTAGTCCACAAAGACCTTTTGATTATCGTCCTAGGCGACTGTCCTCTAGAGCTTCATCTCCGCATTACAATCGTTCAGACCGATCAGAAGATGCTCACTCACCATACACTGAGCGGTCATTCGAAGAAGATAATCAACGATCATTTCATCCATCTCCACCTCCAACTAATTTTCAACAAGATGTGAGAGCTGGTTTAGCTCCATATGTACCACCTCAGCAAAAACCTGAATGGAAAAGGTACAAACAGTACACAAGGTCAGATATCATGTCTGCTATTGAATGTGTTCGAAATGGAATGAGCGCTTTACAAGCCTCCCGTAAATACGGTGTTCCATCACGCACATTGTATGATAAAGTGAAAAAACTAGGCATTACAACGAGTCGCCCTATGAGCCGTGGAGTAAAAAGAGAATCAAACGGTGCCGCTTTCCCTTACGGTCTAAGTGGAACCGGTGGCAACGACGACGGAGCGCCATCAACACCACTTATTGATCCATCGTTCCTTCAACAAGCATTAGAAGGAGCTACTAGAGATGGAGGTCGAGAAGCTTTACACGCAATGGCCTTGGCTGCCGCAGCTCATGCTGCTTTAGCTCCTCGGACCCCACCTCGTTCAGCACCCCAGTCACCCCGATCTCCACCAGCTGATGATGATCATGTTGAAGACCTCTCAGTAGCGCGGCGACGTGATCCTGACCCACCTTCAGGTGTAATAGTACCGCCTCGTAATTTTGCCCTTGATTGCAGCAGCGACAGAGATTGA
Protein Sequence
MGSSEGQQTFCLKWNHHKTNLVEILEALIKVETYVDCTLVVDDQVTFKAHRVVLAANSPYFQSILADVPMDHCSILFPGVKDFEMRALLEYMYTGEVNVTQAHIPRIMKVAEQLEVKGLFDMTELRRRPGSSERTPAASPPRVVPAAPSSVSPPMATTRWPLAPSAPVLSAAYDSADMNPLKRKKLSSMLATRDTPILRNVLAQATPVDSSQPISLVCHPVSQHDSTRLHSNGSAHESERPASPQRPFDYRPRRLSSRASSPHYNRSDRSEDAHSPYTERSFEEDNQRSFHPSPPPTNFQQDVRAGLAPYVPPQQKPEWKRYKQYTRSDIMSAIECVRNGMSALQASRKYGVPSRTLYDKVKKLGITTSRPMSRGVKRESNGAAFPYGLSGTGGNDDGAPSTPLIDPSFLQQALEGATRDGGREALHAMALAAAAHAALAPRTPPRSAPQSPRSPPADDDHVEDLSVARRRDPDPPSGVIVPPRNFALDCSSDRD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00025187;
90% Identity
iTF_00212358; iTF_01080658; iTF_01017861; iTF_00213351; iTF_00159753; iTF_00247116; iTF_00247981; iTF_00213678; iTF_00723279; iTF_00159986; iTF_00247346; iTF_00248247; iTF_01080855; iTF_00722968; iTF_00261986; iTF_00164514; iTF_01178340; iTF_00934662; iTF_01217418; iTF_00687820; iTF_00261773; iTF_00934958; iTF_00403695; iTF_01248015; iTF_01248335; iTF_00687984; iTF_01178769; iTF_00744884; iTF_00744534; iTF_00403959; iTF_00933656; iTF_00786938; iTF_00933979; iTF_00164253; iTF_00786688; iTF_01217632; iTF_00288790; iTF_00288977; iTF_00405847; iTF_00925877; iTF_00406039; iTF_00925655; iTF_01203973; iTF_00430791; iTF_01202600; iTF_01203177; iTF_00430570; iTF_01203371; iTF_01204812; iTF_01205836; iTF_01204206; iTF_01205038; iTF_01206702; iTF_00878799; iTF_01206484; iTF_00878970; iTF_01205629; iTF_01202400; iTF_00115074; iTF_00771204; iTF_00114866; iTF_00771026; iTF_01125606; iTF_01124534; iTF_01125399; iTF_01124730; iTF_00364842; iTF_00408322; iTF_00365068; iTF_00408590; iTF_01071567; iTF_00752210; iTF_00751955; iTF_00074414; iTF_00074413; iTF_00074684; iTF_00074685; iTF_00075406; iTF_00075683; iTF_00076403; iTF_00076711; iTF_01281238; iTF_01281474; iTF_00984972; iTF_00985289; iTF_00960289; iTF_00960100; iTF_00959531; iTF_00418895; iTF_00421487; iTF_00959345; iTF_00958771; iTF_00419701; iTF_00958613; iTF_00420471; iTF_00420663; iTF_00842808; iTF_00419865; iTF_00842585; iTF_00419101; iTF_00421279; iTF_00855982; iTF_00855822; iTF_00876080; iTF_00874377; iTF_00874605; iTF_00875228; iTF_00875455; iTF_00876320; iTF_00695825; iTF_00824897; iTF_00824646; iTF_00695411; iTF_00843674; iTF_00843422; iTF_00986386; iTF_00985923; iTF_00994292; iTF_00994479; iTF_00323420; iTF_00323635; iTF_01385629; iTF_01385943; iTF_01341455; iTF_01387745; iTF_01388393; iTF_01341454; iTF_01386865; iTF_01386642; iTF_01387539; iTF_01341076; iTF_01341079; iTF_01388640; iTF_01020158; iTF_01020450; iTF_01503774; iTF_01504026; iTF_01564831; iTF_01564515;
80% Identity
iTF_00212358;