Basic Information

Gene Symbol
-
Assembly
GCA_907269095.1
Location
OU026141.1:5543041-5546670[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 0.0037 0.35 12.3 3.8 1 23 63 86 63 86 0.96
2 18 0.24 23 6.5 0.0 3 23 113 134 112 134 0.93
3 18 0.016 1.5 10.3 1.8 2 23 157 178 156 178 0.97
4 18 0.00032 0.03 15.6 1.3 1 23 182 204 182 204 0.98
5 18 0.0011 0.11 13.9 0.2 2 19 210 227 209 228 0.96
6 18 0.0028 0.26 12.7 1.6 1 23 238 261 238 261 0.96
7 18 0.014 1.3 10.5 0.8 1 23 267 290 267 290 0.94
8 18 0.76 72 5.0 0.7 1 13 296 308 296 311 0.84
9 18 6.9 6.5e+02 2.0 0.3 2 23 366 388 365 388 0.86
10 18 0.57 54 5.4 0.1 2 23 414 435 414 435 0.96
11 18 0.018 1.7 10.1 3.1 2 23 458 479 458 479 0.97
12 18 5.6e-05 0.0053 18.0 1.5 1 23 483 505 483 505 0.98
13 18 0.026 2.5 9.6 1.2 1 23 510 533 510 533 0.95
14 18 0.013 1.2 10.6 0.2 1 23 539 562 539 562 0.87
15 18 0.035 3.3 9.2 0.9 1 23 569 592 569 592 0.97
16 18 0.0081 0.77 11.2 2.9 1 23 598 620 598 620 0.97
17 18 3.5e-06 0.00033 21.8 3.7 1 23 626 648 626 648 0.98
18 18 7.1e-07 6.7e-05 24.0 0.4 1 23 654 676 654 677 0.96

Sequence Information

Coding Sequence
ATGGAAGCTGGTATTCTCGTTATCGGGCAAAAACCCGAAGAAATTGACGATACGAGTCAAGTGCAAATGCTCGAGACAAGGGGCAGGCGGCGCACAGGGAATACAAAGAGATCGATTTTCAGGAACAACCTAAGAACCATTCTCGATAGCAGTACAGCGTATCCCTTTAAACACAAGAATGGCGTGTTCCATTGCTTCTTTTGTAACACGAAGTTCAGTGATCCTGAGAAACTGAGAGAACACAACCGCTCCTTGCACGGGGACACGAGAAAGTTCGCCGTCTCCTTCACGCCTAATAAGTATGAACCCATTAAGATAGATTTCGGGGAAGCCGCGTGCAGAATTTGCGATGTATCTATTACCAACTACGGGGTTCTGAAAGCACACATCCTCGCTGTGCACGGGAAAGAGATCGACACGTCCTACGGCGAGACGATACTGCCGTACAGTCTCGCCAGAAACGAGAACAAGTGCCAGGTTTGCGGGAAATCGTACGAGCTGTTCCTCACATTGCACAGACACCTCAACGAACACTACAACGATTATATTTGCGAGAACTGCGGCAAGAGATTCGCCACACGAGGCAGAATGTTCAGTCACAGCAAGACTCATTCGCGACAAGACTGGCCTTGTCGGAAGTGCGACAAGAAGTTCGCGACATACTCAGCGTTGCGCTGGCATGATGGCAAAGAGCACGAATGCAGGGTGATGTACAGTTGTCCGATTTGCGAGGAACGATTTACCTCATACCTGCACAGGATGAAGCATCTGAGCTCAGTGCATGGACAGGAGACTCTCTACGCTTGTCCGTCTTGTCCAAAAGTCTACAAGCTGTGCAGTCTCAGGACAGCGCACATAAAATTCGCCCATAAACAGGAAAGGAACCATGAGTGTACGACATGCGGGATGAAGTTCTTCACCAACCGAGCAAAGACTGAAGATAAACAAAAAAAGGCCAAGACTGAACAAAAGAGTGAGGCCAAGACCCGCGAAGAACAGTTGGGCATCGCGAGGCGAGCTGCGTTTATAACCAACATATCGATAATACTGGAGTGCTGCACAGCGTACCCCTTCAAGTATCGGAAGGGGGCTTTTCTTTGCTATTTTTGTATGAACACATATACGGAGCCCGAGGACCTCCGCGAACACTACGCCGAAACGCATACAGACGTGAAACATGTCTTCCTCTCTCGTAAACCTAGGAGTTACGATCCGCTGAAGGTAGATTTCTCAAAAGCAGTTTGCAAGCTATGCGGGTTTCTCATACCGGATTATGAAACGATGAAAACGCATCTTAAGGTACATGGGAAAGCTTTAGACTTGACTCATGGCGAGAGCGTGCTTCCGTACAGTCTGAATAAAGACGAGAATCGGTGTCTGATCTGCAGAAAAGAGTACGAGACGTTCTTTAGTCTGCACAAGCACATGAACGAGCATTTCGAGCGGTATATATGTGAGACTTGTGGGAAGAAATTCGCTACGTATTCGAGGATGATGAACCATACTAGGAGCCACGAACGTGGAAAATTTCCATGCAAAAGATGCGGCGAGACCTTCCTAACCTACTCTTCGATGCACAATCATGTAGCCAAAGCGCACAGATCGAATAACAGATACAAGTGTCCGATATGCGACGAGAAGTTCCCTGAGTACAAGCTGAGATTGGAGCACCTGAGCAACGTTCACGGGAAGAAGCCGGCCGTTTTCCCCTGTCCGTCGTGTCCTAGGATCTTCGACCTGTGCAGTCGGAGGACGGCCCATATAAGGTCTCAGCACTTGATGGAGAGGAACCACGAGTGTACCGAATGCGCGATGAAGTTCTTCACGAATAACGAGCTGCGGAATCATAAGATAAAGCACGGAGGACCGAGGATCCACCAGTGTCAAGTTTGCAAGAAGTCGTATGCGAGAAAGAAGACTCTACGCGAACATATGAGGATACACAATAACGACAGGCGGTTCGTCTGCCCAGTCTGTGGTCAAGCGTTCATACAGAACTCCAGTATGAACCAGCATCTGAGAGTACACCATACGGCTCAAGCCGTTCGTATCAAAACTGATGTTTCGGTTGATTTCAAATAG
Protein Sequence
MEAGILVIGQKPEEIDDTSQVQMLETRGRRRTGNTKRSIFRNNLRTILDSSTAYPFKHKNGVFHCFFCNTKFSDPEKLREHNRSLHGDTRKFAVSFTPNKYEPIKIDFGEAACRICDVSITNYGVLKAHILAVHGKEIDTSYGETILPYSLARNENKCQVCGKSYELFLTLHRHLNEHYNDYICENCGKRFATRGRMFSHSKTHSRQDWPCRKCDKKFATYSALRWHDGKEHECRVMYSCPICEERFTSYLHRMKHLSSVHGQETLYACPSCPKVYKLCSLRTAHIKFAHKQERNHECTTCGMKFFTNRAKTEDKQKKAKTEQKSEAKTREEQLGIARRAAFITNISIILECCTAYPFKYRKGAFLCYFCMNTYTEPEDLREHYAETHTDVKHVFLSRKPRSYDPLKVDFSKAVCKLCGFLIPDYETMKTHLKVHGKALDLTHGESVLPYSLNKDENRCLICRKEYETFFSLHKHMNEHFERYICETCGKKFATYSRMMNHTRSHERGKFPCKRCGETFLTYSSMHNHVAKAHRSNNRYKCPICDEKFPEYKLRLEHLSNVHGKKPAVFPCPSCPRIFDLCSRRTAHIRSQHLMERNHECTECAMKFFTNNELRNHKIKHGGPRIHQCQVCKKSYARKKTLREHMRIHNNDRRFVCPVCGQAFIQNSSMNQHLRVHHTAQAVRIKTDVSVDFK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00209105;
90% Identity
iTF_00209105;
80% Identity
-