Basic Information

Insect: Biston stratarius
Gene Symbol: mod(mdg4)
Assembly: GCA_950106695.1
Location: OX467116.1:22735615-22751621[+]

Transcription Factor Domain

TF Family: BTB
Domain: zf-C2H2|ZBTB
PFAM: PF00651
TF Group: Zinc-Coordinating Group
Description: The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.9e-27 6.4e-25 87.9 0.1 2 99 23 116 22 125 0.92

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.9e-27	6.4e-25	87.9	0.1	2	99	23	116	22	125	0.92

Sequence Information

Coding Sequence: ATGGCGTCGGACGAACAGTTCTCACTATGTTGGAACAACTTCCACGCGAACATGTCGGCAGGCTTTCATGGCCTGCTGTCACGTGGAGATCTCGTAGATGTAACATTGGCTGCCGAAGGCAGATTATTACAAGCACACAAATTAGTACTATCTGTATGCTCGCCGTATTTCCAAGAAATGTTCAAAATGAATCCAACGCAACATCCTATAGtatTTTTAAAAGACGTTAGTCATTCAGCGTTAAGAGACTTATTACAGTTTATGTATCAGGGAGAAGTTAATGTTAAGCAGGAAGAGTTAGCATCGTTTATTAGTACCGCGGAACAGCTTCAAGTTAAAGGTTTAACCGGAAATCAAAACGAAGAAAGTTCCACGCCATCAAAACCAAAGCCGACCTCGAGGCCAGGCCCGAGGTCGTCACAACAAAGGCAATCTGTTATGACTAAGTTAGAGACTGATTTAGATTCTAAGCCCTCCTCAACTCCAGTAGCAGTTAAGCGACCAAATAGGCCATCGATAGCATCAAATAATTCATCATCGTCACAAAGCGGACCCGCTAAACGAAAATGTGTAGACCCATTAGAAGCAGGACCCTCTGGATCGGCTAAAGAAGAATTTGTTACGATACCTGACGAAGATGAAAATAACGCTGTGGCACCTAAAATGGAACCAGAATTTGTCAATGAAAGTATGTGGGATGAAGACGAAGGAGACACTAACAATGATGAGACGAATTTTGGTGAAGATGACTCTAATATGGAAATGACTGGTTTTGATGGTTCTACTACTGGTGATGGCAATATAACTGGAGGAGAAGGTGGCGCAGTGGGTGACGCACAAGAGGTGGAGGTGCGGTACACGGTGAcgcggcgcggcgcgccggCGCTGCTCATCGGCGGGTTTGGGTACGTGGCGCGTaagcggcgcggcgcgcgcgttTACTGGACTTGTCGCGCACGTCGCCTCGGCTGCCCGGCGCGCGCGCTCACCGCTGACGGCCGTCTACTAGCGCACACGGCGGGGCACACCCACGCGTCGCCGGCGTCGACGCACGCCGCCACACCCGGCGCCGAGTCCGATCTGGAGTTCGTGATATCGAACCGCGGCCGGAGGCACATGCGACTCGGCGGGTTCTCGTTTTACGCGGAGAAAGTGTTCCCGGAGAAGAGCAAGGTGCGGTGGCGGTGCACGCGGCGCACGTGCCGCGCGTACGCGCACACGCTGCACGACCGCATCTTCGCGCTCAGCAACAACCACTCGCACGCGCCGCCTGGCgtgcccgccgccgccgccgccgcgctcgCTGCGCATCGCTCCTTCGCGCACGCGGCGTTCGCCGCCGCCGCGGTCAAGGCTGTGCTCGACGATTAA
Protein Sequence: MASDEQFSLCWNNFHANMSAGFHGLLSRGDLVDVTLAAEGRLLQAHKLVLSVCSPYFQEMFKMNPTQHPIVFLKDVSHSALRDLLQFMYQGEVNVKQEELASFISTAEQLQVKGLTGNQNEESSTPSKPKPTSRPGPRSSQQRQSVMTKLETDLDSKPSSTPVAVKRPNRPSIASNNSSSSQSGPAKRKCVDPLEAGPSGSAKEEFVTIPDEDENNAVAPKMEPEFVNESMWDEDEGDTNNDETNFGEDDSNMEMTGFDGSTTGDGNITGGEGGAVGDAQEVEVRYTVTRRGAPALLIGGFGYVARKRRGARVYWTCRARRLGCPARALTADGRLLAHTAGHTHASPASTHAATPGAESDLEFVISNRGRRHMRLGGFSFYAEKVFPEKSKVRWRCTRRTCRAYAHTLHDRIFALSNNHSHAPPGVPAAAAAALAAHRSFAHAAFAAAAVKAVLDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01172515; iTF_00650154; iTF_00026984; iTF_01193707; iTF_00701197; iTF_00321711; iTF_00771189; iTF_00018293; iTF_00809301; iTF_01342342; iTF_00785327; iTF_01221726; iTF_00327193; iTF_01425237;
90% Identity: iTF_01172515; iTF_00650154;
80% Identity: -