Bbet024583.1
Basic Information
- Insect
- Biston betularia
- Gene Symbol
- -
- Assembly
- GCA_905404145.1
- Location
- FR989876.1:2585619-2596546[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 20 2.4 1.9e+02 3.4 0.2 2 23 111 132 110 132 0.95 2 20 0.00064 0.051 14.6 0.3 2 23 136 158 135 158 0.89 3 20 1.7 1.3e+02 3.9 1.5 1 23 208 230 208 231 0.94 4 20 0.011 0.9 10.7 2.6 3 23 381 402 379 402 0.95 5 20 6.1 4.9e+02 2.1 0.0 3 19 412 428 410 430 0.95 6 20 0.22 17 6.7 0.3 2 23 441 462 440 462 0.94 7 20 1.2 99 4.3 2.1 5 23 513 532 511 532 0.94 8 20 0.061 4.9 8.4 3.2 2 23 541 562 540 563 0.94 9 20 2.8 2.3e+02 3.2 3.5 1 23 570 595 570 595 0.89 10 20 0.27 22 6.4 1.1 3 23 606 627 604 627 0.93 11 20 7.6 6e+02 1.8 3.5 1 23 632 655 632 655 0.95 12 20 0.0012 0.094 13.8 4.2 1 23 661 683 661 683 0.97 13 20 0.0001 0.0081 17.2 1.8 1 23 690 712 690 712 0.98 14 20 8.8e-05 0.007 17.4 2.3 1 23 717 739 717 739 0.96 15 20 0.0014 0.11 13.6 2.4 1 23 745 767 745 767 0.97 16 20 2e-06 0.00016 22.5 1.2 1 23 773 795 773 795 0.97 17 20 3.5e-05 0.0028 18.6 2.2 2 23 802 823 802 823 0.98 18 20 0.0022 0.18 12.9 0.4 2 23 833 855 832 855 0.97 19 20 5.9e-05 0.0047 17.9 0.8 1 23 860 882 860 882 0.99 20 20 0.0031 0.25 12.5 4.8 1 23 888 911 888 911 0.97
Sequence Information
- Coding Sequence
- ATGTCTTCCGACGATTCTGAGGATGAGCCCCTGTCCGTCTTGGCGGCACTGAAAAAACGAGATGAATCAGGGCTTGAAATATACCCAATAATTAAAACTGAAGGTTCTACATCGAAACTCTTAATAAAAAAGGAATGCGACATATCTATAACACTTCAGCAGCAGTTGCAGAGTGGGCTGCTACCGGCAATTGTCGAAAGGCCGACAGATGTATGGTTGTATTTAACAGATTTTAATTTAACCGGGCCGTATACTTGCCTCCTCTGTTCTGAGTGGTTCATTAATAGGAATAGAATTGTCATACACTATGTGATCGATCACAAAAAAGATTACTGTGGAATCTGCAGATACTTAGTACCAAACAGAGAAACATGGTGGCAGCATCAAAAATTCCATATCCCATGGAAATGCTCACAATGTACTGAAAGTTTTCCAGTTCAGTCAGAGCTTCGTAAGCATTTCAGTGCTGCTCACAATCTTGTTCATTGCCACTTCTGCTACTTGCGCCTTCCTGATGGTGACCAATATCACAAGCATTTGCTTCAAAAACATTGTGTCACCAAAGTATCTGGTATTCATGGAGATTGTCTGTGGGATTTTGAATGCACAGGCAACCAGAATTTTCAGTGCCTACTCTGTTCAAAGTCAGTAAATGTTGGTCGACAATTTGCAGACCATTTCATGTCTCATCATCACTTTACTCTTAAATGCTTCATGTTCTACGTTGCCGGCATTGATCTACCATTTAAAGTAAAAGGTGCAGAGTTAACACCAGATTTTGTTGATACACAACTCAAAGCATATAGCACTTTTGGTTATGTTGACTTTATAAAGAGCCTGAAATTCAAAGAAGAATCTGTGACAGTTACTGAAGAAATTCCAATTACAGTTCATTGTGAACCAGAGTTTAAGGAACATAGTGAAAATGATGATGATGGTGAAGATTTAAAGCTCAGCGAGGAAATAAAGTGTTACAGAGGAATTCCTGACTTTGACGTTTCACATATAGAAGTAATAACAACACAAGAATGCTATTCTGAATATATTGAAGGAACATTAAACAAACTAAATTTAAATGTAATGCCTGAATCATCAGAAATTACCTACCCGAATTTTGCTATTGAATCAAAACCAATCAACTGTTGCCTTTGTACTGAAGTATTTATGAAAAAAAATAATTTGGAAAGCCACATGACTAAATCTCATGGCATAAAAGCCCTGCCGATTTACTGGTGTAGAGTTTGTGCTGCGGCATTTGATAGTTTCTCAGAGTTGGAGATTCATTCTGCACAAGAATTAAGTGAATTCGGGGATCTGTGGATTTGTCAGTTCTGTGATCAAGAGTTTGATGGCCGAGAAGACACTAGGAAACATTTGACTGAACACTGGCATGAATTACAGTATGATAACTGCTTCAGTCCACACCTAGGATTCAAATGCAAGTTCTGTCCGATTCTCTTTTGGAACGAGACTGACAGAGAGTCTCACCATGTTAACATGCACGCTGAAAAGAACAAGGTCGACTTTTATCACTGTATATGTGATGAGGTTTTTGGTGATAAGGTATTTTTCGTCCATCACTATCTAACCAAACACAATTGTGATACTTCATATCTCCTAAAATGCTGTATTTGTTCCATCGTGTTTGAGTATGTAGACGACTTGAGGAGTCACTTTAAAAACCATCATCCGGAGGCCAAAAAAATATTTTGTTGCTTGGATGATTGCAAATACAGGCCTTTTAGCCAGAGGAAATCTTTCCTTATACATTTAAAGTCATTCCACGATCCGATAGCTCGGCCCCGCCCGTCTAACTGTGAGACGTGCGGTCTAGAGTTCACTACCGCTAAAGCTTGCTCCCAGCACGTTAACAAAGTTCACGGACCTGGCAGATTCCACTGCACTCTCTGCGAGGAGAAGTTGCACACTAATGACGAAAGAAAGATCCACTACCTCGTCCGTCACCCGGGCCGTAACCAGTACCAATGCCACGCGTGCGATAAATCCTTCCAATACAAATCGTCGCTCTACATGCATAAACAGGAGCATTCGCCGTATAAGAAGGATTATACTTGCAGTTATTGCGGGAAGAACTTCTTGAAAAAAGATTCCTACAGAGAACACATGATGATTCACGAAGCGCCGCGACACGCTTGCTCGTATTGTCCGATGCGGTTCGTGCAACGCTCCAACATGTTGCGCCACGAGCGGAGGCATACCGGAGAGAGGCCCTACGCCTGTCAATATTGTCCGAGGACCTTCTCCGATAAAGGCGCTTGTACTTCGCATTCGAGGACACATATAAAGACTACATCGTTCGCATGCGTTTATTGTGGACAAACCTTCGTGCAGAAATCCAAGCTTACTTACCATATACGGAAGCACACTGGAGAAAATTTGGAGACATGCACGGTGTGTTCGAAAATATTTACAAGCGCGTGCTCATTGCGAGAACACATGCGAATACATCAAAGGACGAAATTGAAGAAGACAATCAAATGCCCCCTTTGCAAGAATATGTATTCCATGGAGCGTGACATGCTACGTCACATGCGCACAGCGCACACTGGTGTTCAATTCAAGTGTCCACTGTGCCGGAAATGTCTCCGAAATCCCGGCGCGCTTCGGGACCACGTGTTGACACACAGCCGCGTCAACACTTACCGGTGCAAACTCTGCCCGAAATCGTACCACACGAAGAAGTCCATAACTAAACACTTAGAAAAACGTCATGATATAGAACCTATCAATACTCAAAATCATTACCGGCATCTTGACCCCAAAGAATGCGAGTTAGGTCTAGACGATGAGGTAATGGAAAAGATATTTGGCAATGCCAAAAAGACAAGAAAGACGGACATTATGTATGAAGGCTTTGCCACTTATAATAATGGTAATCAGCTGTCACAAGAAATAAGTGACTATAATCTTGTAGAAAAACAGATTGAAGGAACATCTTATGTACAAAGTGTCGAAGTAAAACTGGAGCCTGAAGATGAAGAAGATATTGAAGAGGTGCCTTCACCGGACTTCGTTAACGTAAAGATAGAAAGTATGGAAGAAGAATAA
- Protein Sequence
- MSSDDSEDEPLSVLAALKKRDESGLEIYPIIKTEGSTSKLLIKKECDISITLQQQLQSGLLPAIVERPTDVWLYLTDFNLTGPYTCLLCSEWFINRNRIVIHYVIDHKKDYCGICRYLVPNRETWWQHQKFHIPWKCSQCTESFPVQSELRKHFSAAHNLVHCHFCYLRLPDGDQYHKHLLQKHCVTKVSGIHGDCLWDFECTGNQNFQCLLCSKSVNVGRQFADHFMSHHHFTLKCFMFYVAGIDLPFKVKGAELTPDFVDTQLKAYSTFGYVDFIKSLKFKEESVTVTEEIPITVHCEPEFKEHSENDDDGEDLKLSEEIKCYRGIPDFDVSHIEVITTQECYSEYIEGTLNKLNLNVMPESSEITYPNFAIESKPINCCLCTEVFMKKNNLESHMTKSHGIKALPIYWCRVCAAAFDSFSELEIHSAQELSEFGDLWICQFCDQEFDGREDTRKHLTEHWHELQYDNCFSPHLGFKCKFCPILFWNETDRESHHVNMHAEKNKVDFYHCICDEVFGDKVFFVHHYLTKHNCDTSYLLKCCICSIVFEYVDDLRSHFKNHHPEAKKIFCCLDDCKYRPFSQRKSFLIHLKSFHDPIARPRPSNCETCGLEFTTAKACSQHVNKVHGPGRFHCTLCEEKLHTNDERKIHYLVRHPGRNQYQCHACDKSFQYKSSLYMHKQEHSPYKKDYTCSYCGKNFLKKDSYREHMMIHEAPRHACSYCPMRFVQRSNMLRHERRHTGERPYACQYCPRTFSDKGACTSHSRTHIKTTSFACVYCGQTFVQKSKLTYHIRKHTGENLETCTVCSKIFTSACSLREHMRIHQRTKLKKTIKCPLCKNMYSMERDMLRHMRTAHTGVQFKCPLCRKCLRNPGALRDHVLTHSRVNTYRCKLCPKSYHTKKSITKHLEKRHDIEPINTQNHYRHLDPKECELGLDDEVMEKIFGNAKKTRKTDIMYEGFATYNNGNQLSQEISDYNLVEKQIEGTSYVQSVEVKLEPEDEEDIEEVPSPDFVNVKIESMEEE
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00666804;
- 90% Identity
- iTF_00207245;
- 80% Identity
- -