Basic Information

Insect: Biston betularia
Gene Symbol: PLAGL2
Assembly: GCA_905404145.1
Location: FR989884.1:4605047-4606639[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0003 0.024 15.7 1.0 1 23 121 143 121 143 0.96

2 7 7.7e-05 0.0062 17.5 1.5 1 23 149 171 149 171 0.96

3 7 3.5e-08 2.8e-06 28.0 1.9 1 23 177 199 177 199 0.97

4 7 0.0035 0.28 12.3 0.7 1 23 206 230 206 230 0.94

5 7 6.1e-05 0.0049 17.8 0.4 2 23 238 259 237 259 0.97

6 7 0.00013 0.01 16.8 1.3 1 23 273 295 273 295 0.97

7 7 4.4e-06 0.00035 21.5 1.2 1 23 301 324 301 324 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0003	0.024	15.7	1.0	1	23	121	143	121	143	0.96
2	7	7.7e-05	0.0062	17.5	1.5	1	23	149	171	149	171	0.96
3	7	3.5e-08	2.8e-06	28.0	1.9	1	23	177	199	177	199	0.97
4	7	0.0035	0.28	12.3	0.7	1	23	206	230	206	230	0.94
5	7	6.1e-05	0.0049	17.8	0.4	2	23	238	259	237	259	0.97
6	7	0.00013	0.01	16.8	1.3	1	23	273	295	273	295	0.97
7	7	4.4e-06	0.00035	21.5	1.2	1	23	301	324	301	324	0.96

Sequence Information

Coding Sequence: ATGGCCAGTTCGCCACCGAACCCTAGAGAAGGAGAGGAGCTCGGAGCCACCTCCGAGCCCGCGGAGACGGGCGGGGAGAGCGCGTCCGCCGCGCAGAAGAGGTTCATAGCGCCGCCCGCATCGCAGGTGCCCTCAAGGCTGCATTTCGTGTCGCTGGGTCCTAGCGGGCCTGCCGGCGTTAAGTCCACCTTCCGCACGGTGAAGGTGGCGCGGCGCGTCCCCACGCTGCCGCGCAAGTTGTCACCGGCGGCGGGGCCGGCGGCCGCCGGCGCGTCCACGTCGGCCGCGCCGCCCGCGCCGCCACCGCCGCCGCCGCCGCCTGAGCCGCCTCGTCGCACTCGCCGCGATCAGGCCAAGCGCCATGCCTGTGACACCTGTGCTAAACGATTTACCAGCCCAGGGAAACTCAGCCAGCACCTTCTCTCACACACCGGTGAGCTACCCTTCCCATGCGAATTTTGCGATAAACGATTCAATTCTAAATTTAAGCTAGCACGCCACAACCTCATACACAGCGAAGCAAGGGCCTTCGCTTGCAATGTGTGCGGAAAAACTTTCAACCGCAAAGATCATCTTACTAACCATGTTCGAGTGCACAATCCTGTCAAAAAGCTTTATACGTGTGAGAAACCTGATTGCAGAAAGTCTTACACCTCATTGATGAGTTATAGAAAACATGCAGCTTTGCATTCTGTTGAGGAAGGAAACTTGCAATGTAAAATATGTGATAGAGTCTTCACTAATCGCCAAGATATTGTTTATCATTTAAAGATCCATACAGGTAGTCGCACTGTAAAGAATGAAACTGACAAAAAGTTTACATGCAACTATTGTGAGAGAAGGTTTTTCACGGCGAAGGATGTGCGGCGTCACCTGGTAGTGCATACGGGGAGACGTGATTTCATGTGTCCTTATTGCCCTCAAAAGTTTGGGCGAAAAGACCACCTGGTGAGGCATGTCAAGAATGCACATCCCGATGAGTCTTGGCGGTCTGCAGCTGTTGGAACCTCTAGCGACCCTACACCCGAGGCATCTGCTTTTGAAGAGACTTATACGACAGAATTCGCGGTAGAGGGTACCGATTATACTATCTGGAAACCTGAAGAGTCTTCTGAAGAGTCGAAACCCGTGCGGACGCCGGTACCCTCGTCAGAGATCATCGTAGAGATGCCATCTGAGCTCAACATCAAAATGGAGCCTGGAGCAGACTTAGATGTAAAAGTAGAAGGTGGAGATCCTTTAGAGATAAAGTTAGAACAGCCACCGTCGCCGAGTTGTGCCCTGTACCCTCTGGTGTATGTAGTACCTCAATACCAGCCGCCGGCCAACTTGCCTTACATCACGGAGGCGTTACCAGACACAATGGAGGCGCATTTACTTGACCCCAGCGTTGAGCTTTATGACCCGGGCGAAGGGCCTTCGGGGCTGTCGACTCAGGTGCTTCGAGGTCTACTTGAAGAACCCGAGTCGACATACCCGGCTGAAGAGAGCGGCAGCGGCACGCGGTCGCAGCAGCGTCTGCCAGCGTTCACGCAAGCTTTCCAAACCGCCCAAAGTTCGAAGCCGCCGCCGCCTCCGCCCCCGCCACACTAA
Protein Sequence: MASSPPNPREGEELGATSEPAETGGESASAAQKRFIAPPASQVPSRLHFVSLGPSGPAGVKSTFRTVKVARRVPTLPRKLSPAAGPAAAGASTSAAPPAPPPPPPPPEPPRRTRRDQAKRHACDTCAKRFTSPGKLSQHLLSHTGELPFPCEFCDKRFNSKFKLARHNLIHSEARAFACNVCGKTFNRKDHLTNHVRVHNPVKKLYTCEKPDCRKSYTSLMSYRKHAALHSVEEGNLQCKICDRVFTNRQDIVYHLKIHTGSRTVKNETDKKFTCNYCERRFFTAKDVRRHLVVHTGRRDFMCPYCPQKFGRKDHLVRHVKNAHPDESWRSAAVGTSSDPTPEASAFEETYTTEFAVEGTDYTIWKPEESSEESKPVRTPVPSSEIIVEMPSELNIKMEPGADLDVKVEGGDPLEIKLEQPPSPSCALYPLVYVVPQYQPPANLPYITEALPDTMEAHLLDPSVELYDPGEGPSGLSTQVLRGLLEEPESTYPAEESGSGTRSQQRLPAFTQAFQTAQSSKPPPPPPPPH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01209629;
90% Identity: iTF_00207249; iTF_00666771; iTF_00033196; iTF_00034088; iTF_00143309; iTF_00926894; iTF_00826136; iTF_00827309; iTF_00044775;
80% Identity: -