Btha010766.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bhutanitis thaidina
Gene Symbol
MBD-R2
Assembly
GCA_029286595.1
Location
JAGSMS010000018.1:8092136-8108449[+]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 4.5e-16 1.3e-12 47.3 0.0 5 63 758 815 754 832 0.90

Sequence Information

Coding Sequence
ATGGCAGTTAAAAAGTGTTGTATTGAAAACTGTCTATCATGTTCAACAAGAAACGAAGATGTTGGTGTTACATATCATAAGTATCCTAAAGATATCACTTTATGTGACATATGGATATCTGTTACACGGCACAGACACTTTGACATAGGAACAACTTCCTATGTGTGTTCACGACACTTTTGTAAAAGTGATTTTCAAGTTTACAAGGACTCAAAATATATCTTGAAGTCAGATGCAGTACCATCAATATTTCCTTGGGATATAACAATGAATATGGATTCAGATATAAATGTTGaggaaaaaaatgaaaataataaagatacatTAAGCAGAAGTAAGGAGTCAGAGCCCGAAAATTTGgatgacataaaaaaatttatagaagACCAAGAGAAGATCATTCAGAAACAAAAATGTGAGGCTAAAAATTTAGTATTAGAAGAAGGAAATATCAGTAGAGAAATTAAAGTCGAAAGTCCCGATAGTCCTAAAATTCAAGACGAAACTCTGACAGTAGCTACTAGTGTAATGGATTTCATATTAAGTGAATCAGAAGCCAGGATTTTgactaaaaaagaagaaaaaagtacTGAAAAAGAGTGCCTCTGTCCTGGTGAAAAAGGGAATAGTAGTATGGCTTTGTCAGTTGGTTCTAAAGTTGAGGCGAAGGATTTTGGAGAATTTTGGTATCCTGCCCAAATTATTGAAGTAGATTATGATGAGATGGAAGTATTAGTGCATTATGACAATGCTTCCAAAAAgcATGATGAATGGATAAATGTCAGCAGTCCTAGGCTAAGACCTATAAGCTATAGTTCGCCGAAATCACCAGCCATGGCTAATACTGAAGTTCTGAAAACTGAAACCAGTCATGTAAAAGAAGAACTTAAATCAGATGAGAAGCCAAAATTAAAGTTTGTTGTTGGAGAAAGGTGTTTGGCACGATGGAGAGATAATCGGAGATTTGTAGCTACAATAAATAAAGACTTAGGCAATGgCTCTTACGAGATTATATTTGATGACGGCTTCCAGTGGAAGTGTACCATGAGTAGGCTATATAAGCTTAAACAATCCACAGAAAGAAGTTCTGACACTTTAACCGTTGACACATCATCTCCGTCATCGTCCTTCTCTTTTCCTTCTCCTATTCCTTATGGAGCTGGTCCCAGTAGTTTGCCCCAATTGCCTGCTTTCCACACTCACCTCTTTGACCCAACCCGTGATTATTTAGGTACGAAAAGCGAGCGTCGCGAAAAGAAACGCAAgttgaatataaaagaaatatttaatattggtcagaagaagaggaggaagcAGAGGTCACCGACTGAAACTGAAATCCCATCACctagaattattaaaaagagaaaaaggaCTGTCATAATAAAAACTGAATTGGAAGTTGCCTCTGAGACTAAGCCAGTTAAGATTGAAGTGAAAAGTGAAATCCCGgatGCTGTAGCATCCATAATTGGTACAGTAGCCAAAGACGAGGTGGTCATTAAACAAGAAACAACATGTGATGATAAATCTCCAACTGCAGTTATGGAACAGAGAACACGACGTGATATAGGTAACGTTcctcaaaaaaattacaatgataaACAACTCAATGCTTTTGTTGGTACCAATCAGGATACTGAAATGACAGATATTAAAAACAAGAGTTTGGATCCAGTGTTAGAAGAGGAAACAAAACTTGAGAACTTTGAAATAACAGATAATCGAAAGCACGAGGAAGTTATTGATAGGATAAAAGAGGTTATAACCAAGTTAGAGGATGGTATAAGTAAGGCGGAAAAGATAGATTCCCCTAAAGTAGAAATTAAAGAAGATAACAAAGATATTAAAGACGAAACAGTAAATACTACAGTTGAAGAAAAGGAGGATAAAGTGACTCCATGTGAAAAgccaaagaaaattaaaactgaaaataatgaaataaagcccaaaaaaaatttgtctaaaattaaaaaaagtaaaaaattaagattgttacaggaaaaaaaggttaaaaagcAGGTGGAAAAAGTTAAGTGTGAATTGGAAGAGATGAAACGACAAGTGGAAGAgatgaaaaaacaaatgttattgaAGACTGAAGTGTTAACAAGCTCTCAACAGAGTCAGGAAATGCCAGAAAGTTTTCTTCTGCCCGGGGAGTGGTGCTGCAGATGGGTAAACGGTCAACCGGTAGGAAAAGTCAGTGAGATAGAAAGTGAAGTAAAGGTTGATGCATACAGTAAGCCTGCTTTACCAAGACGCAGTGTTCAGGTTGAAGATAAGCGGCTGCCTGAAGGATGGACAAAACACATGGTTCGTCGGAGTTTTGGAAACTCAGCTGGCAAATGGGATGTTGTGTTAGTTAgTCCTGATAATCGACGTTTCCATACAAAAAATGACATGCGATGCTATCTTGAGAGCAGTCCTAGCAAAGAACTAAAACACTACGAGAATGCGTTACTCGACTTCGGCGTTCATCTCAAGCTCTCCAGACGGATGGGATGGATCACTAACACCGGTACGGAAGAACCGGTTACGCCATTACCAGCCGGTTTAATGAGCAGCACGTCGCCTTtggtaaaaaaaaggaaactggGCCTGAATAGGGCAAAGGGCATTATGAAAGTAAAGGACAAGAAGAGGTTTGGTGGCAAGATTCGAAGAATGCATAATTTTTCGATTGACACATTGCCAGGGACGAGTGAAGATAATTTGTATGAATCTTCTGATTTACACGCTGAAATAGCGGTACCGACGTTAGAAGATGGTTACGTTTATGTTGGGTCATTAAAAGTTGAAGTTATTGACAACTTATTGCGTTGTCCGGCTGAAGACTGCTTAAAGAATTtcagaaataacacattgtTAAAAATGCACATAAAACATTATCATAGGGAGCTGAGAAAGATGCTCGGTACCACTCCCAAGGTCCTAGATTTGGCTTATGCTAGAACTAAACCTTCTAAAGCAGAAAGGACTAAATTAAGAAATGGAAAAAATAGTAAGGTCATCAAGGTTAAAATACCGAGACCGCCGAAACGCACCGAAGAATCAAAAATAGATCTGATAAAACTTGATTCTGAACTGCAAATTGATATACCCCTTTCACCGACAAAGGATCTAGAGCATGCGCCAAGGTCACAGGATTCACCAAAATTGCGTAATGCACTAGTAAATAAACCAGTTAAAAGGCCTAGAATTCTCCTTCCTGTAAGGAGACCAGACGTAGAAGTAAATGAAACTACAGAAGAATTGGGTATAAGAGGGCTTTCCCCAGTTAATATACCGGCAGTAGAGGCGCTTGACTTTGAAACTGCTATTTCAACTCACACCGTAACAAAACCAGCTGTAGAATGTAAAAAGAAGCGTAAAGGTTTCGCTACGATTCACAAGAGGCCAATGAGTGAGGATGAAGAATGGTTAACTATGAACTCGGATATAGAGACGAGGTCTAGCTTCCCGGGCTCCGGGACACCCGATTCAAAGATAATGGATAACAGAACATCTATTATTGCGGCCGCGTCGTCCGAGTCCAATGAAGACCAAAAGGAATCAATGTATATGTATGCAGAAAATGGTGAACGTATCAAGATAGTTCAAATGAAGCGCGAGGAGATCATAAACTGTCACTGTGGCTTCCGTGAGGAGGACGGGCTTATGGTGCAGTGCGAGTTGTGCCTCTGTTGGCAGCATGCTCTCTGTCACAATATACAAAAGGAGTCTGAGGTTCCAGAAAAATATACGTGCAGCATCTGCCTGAACCCTCGTCGTGGTCGGCGCTCAAAACGTTTCGTGCACGACCAGGACCGTCTGTATGAGGGGCTGTTGCCGGGAGCGCGACCGTGTGAAGCGCTGCGCCGCTCGCACGAGCTGGCCGGCAACCTGCTGCGCGTGCAGGATGCGCTGCACGCGCTGCGCGTCAAGTACTACGTCGCCACgaagaAAGATCACCCAAAACTATACCTGTGGGCAAAGGACTGGGAGACGACAGAGTTGAGCATTACTCAAGAAAAATTGAACTCTGACTATTCTgaccttaatattataattaataacattgggAAAGAGAACTTACCTGTAAAAACAGACGAAATTAAAGATCtgcaaatggaaatccgtacgCCGTCATACGAGGAACACGACGAGAGATTTAGCCAGAGAGAGATTCCCCTTGGCTCTCAGACTCTACTAAGTGGGTTGTTATCGAGCCCTGGTGGTGCTTCCTTAGAACTGCCTATTAGCACTTTTGAGTTAGAAAGATTGGCGAAATCTGTTCAAGAGCAAGCGGGCGAGATGCGCGCGCCGCAGCCCGAGGCCGCGATCGAGGACGACGCGTGCCGCGAGCGCCTGCTGCGCCACGTACAGCGCTGCCAGGCGCTCGTCGACGCCAGGCTCGACTCCATCGAGGCGCAGGTCGCCGagtTGGAATCTCAGGACCCATCGTTCGAGGACGACGAAACTGCCGACTATTTCCCGCGGACCAAGCAGACTATTCAAATGCTGATGCGCGATCTCGATACTATGGAGGAGCTTGGAGTCATTACTTGA
Protein Sequence
MAVKKCCIENCLSCSTRNEDVGVTYHKYPKDITLCDIWISVTRHRHFDIGTTSYVCSRHFCKSDFQVYKDSKYILKSDAVPSIFPWDITMNMDSDINVEEKNENNKDTLSRSKESEPENLDDIKKFIEDQEKIIQKQKCEAKNLVLEEGNISREIKVESPDSPKIQDETLTVATSVMDFILSESEARILTKKEEKSTEKECLCPGEKGNSSMALSVGSKVEAKDFGEFWYPAQIIEVDYDEMEVLVHYDNASKKHDEWINVSSPRLRPISYSSPKSPAMANTEVLKTETSHVKEELKSDEKPKLKFVVGERCLARWRDNRRFVATINKDLGNGSYEIIFDDGFQWKCTMSRLYKLKQSTERSSDTLTVDTSSPSSSFSFPSPIPYGAGPSSLPQLPAFHTHLFDPTRDYLGTKSERREKKRKLNIKEIFNIGQKKRRKQRSPTETEIPSPRIIKKRKRTVIIKTELEVASETKPVKIEVKSEIPDAVASIIGTVAKDEVVIKQETTCDDKSPTAVMEQRTRRDIGNVPQKNYNDKQLNAFVGTNQDTEMTDIKNKSLDPVLEEETKLENFEITDNRKHEEVIDRIKEVITKLEDGISKAEKIDSPKVEIKEDNKDIKDETVNTTVEEKEDKVTPCEKPKKIKTENNEIKPKKNLSKIKKSKKLRLLQEKKVKKQVEKVKCELEEMKRQVEEMKKQMLLKTEVLTSSQQSQEMPESFLLPGEWCCRWVNGQPVGKVSEIESEVKVDAYSKPALPRRSVQVEDKRLPEGWTKHMVRRSFGNSAGKWDVVLVSPDNRRFHTKNDMRCYLESSPSKELKHYENALLDFGVHLKLSRRMGWITNTGTEEPVTPLPAGLMSSTSPLVKKRKLGLNRAKGIMKVKDKKRFGGKIRRMHNFSIDTLPGTSEDNLYESSDLHAEIAVPTLEDGYVYVGSLKVEVIDNLLRCPAEDCLKNFRNNTLLKMHIKHYHRELRKMLGTTPKVLDLAYARTKPSKAERTKLRNGKNSKVIKVKIPRPPKRTEESKIDLIKLDSELQIDIPLSPTKDLEHAPRSQDSPKLRNALVNKPVKRPRILLPVRRPDVEVNETTEELGIRGLSPVNIPAVEALDFETAISTHTVTKPAVECKKKRKGFATIHKRPMSEDEEWLTMNSDIETRSSFPGSGTPDSKIMDNRTSIIAAASSESNEDQKESMYMYAENGERIKIVQMKREEIINCHCGFREEDGLMVQCELCLCWQHALCHNIQKESEVPEKYTCSICLNPRRGRRSKRFVHDQDRLYEGLLPGARPCEALRRSHELAGNLLRVQDALHALRVKYYVATKKDHPKLYLWAKDWETTELSITQEKLNSDYSDLNIIINNIGKENLPVKTDEIKDLQMEIRTPSYEEHDERFSQREIPLGSQTLLSGLLSSPGGASLELPISTFELERLAKSVQEQAGEMRAPQPEAAIEDDACRERLLRHVQRCQALVDARLDSIEAQVAELESQDPSFEDDETADYFPRTKQTIQMLMRDLDTMEELGVIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00204421;
90% Identity
iTF_00204421;
80% Identity
iTF_00204421;