Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 5 0.075 4.4e+02 2.0 0.0 22 45 43 67 33 70 0.81

2 5 0.00055 3.2 8.9 0.2 23 45 73 95 69 98 0.91

3 5 5e-06 0.029 15.4 0.0 20 48 98 125 94 131 0.85

4 5 0.0038 22 6.2 0.1 21 52 127 158 124 159 0.89

5 5 5.9e-05 0.34 12.0 0.1 20 48 154 181 153 185 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	5	0.075	4.4e+02	2.0	0.0	22	45	43	67	33	70	0.81
2	5	0.00055	3.2	8.9	0.2	23	45	73	95	69	98	0.91
3	5	5e-06	0.029	15.4	0.0	20	48	98	125	94	131	0.85
4	5	0.0038	22	6.2	0.1	21	52	127	158	124	159	0.89
5	5	5.9e-05	0.34	12.0	0.1	20	48	154	181	153	185	0.88

Coding Sequence: ATGGCCACTACCACTGAAGCCACTACAGAACTTAGACCAAATTACACTTGCCGAAGGTGTAAAGTCACATTCCACACAAAACGCGAATCACTGCTCCATAAAAAGCTAATACACGATTCCGATCCGGAACAGAGTAAATACGTTTGTAAGATATGTAATAAAGGATTTGCAAATCACGGCAACATGTACCGCCACTTAAAAGGTCACGGTGATATTCGACCGCATACATGCCGCGTATGTGGCAAATCGTTTGCGCAGGCTGCCAATCTCAATCGACACTATTCAGTGCACAACGGTGAGCGACCGTTCACATGCTCGGTCTGCTCGAAAGGATTCACGCAACAGGGCAATCTTCGACGTCACGAATTAATTCATACCGGCGAAAAGCCGTTTCGTTGTAAACGTTGCGGTCGAATGTTTTCGCAACGGATCAATCTTAAGAAGCACGTCATGTTGCATCAGGGTTACAAGCCGTACACATGCGAAATTTGCAATAAATCCTTTCTGCAGGCACAAAACTACAAGAAACATTTGCAACGTCACGAGGAGAAGGGTATCAAGTCGGAAAACAGCGATTTATTGTATGAGTGTGCCATGTGTGGTGTAGTTTTTAGTAATTTTGCCGATTTTCAAGGACATGAAATATTCTGCGAGGTCGCTGGAGAGGAACAGATTGAAACGACTACCTTTGAATTGgagcaacagcaacaacaggaacagcagcaacaacagcagcagcagcctCAACAACACCAAACGCAACAGCATCAACAGCAAATTACCCACACAGTTCATTCGTAG
Protein Sequence: MATTTEATTELRPNYTCRRCKVTFHTKRESLLHKKLIHDSDPEQSKYVCKICNKGFANHGNMYRHLKGHGDIRPHTCRVCGKSFAQAANLNRHYSVHNGERPFTCSVCSKGFTQQGNLRRHELIHTGEKPFRCKRCGRMFSQRINLKKHVMLHQGYKPYTCEICNKSFLQAQNYKKHLQRHEEKGIKSENSDLLYECAMCGVVFSNFADFQGHEIFCEVAGEEQIETTTFELEQQQQQEQQQQQQQQPQQHQTQQHQQQITHTVHS

Sequence clustering based on sequence similarity using MMseqs2