Basic Information

Transcription Factor Domain

TF Family: zf-GAGA
Domain: zf-GAGA domain
PFAM: PF09237
TF Group: Zinc-Coordinating Group
Description: Members of this family bind to a 5'-GAGAG-3' DNA consensus binding site, and contain a Cys2-His2 zinc finger core as well as an N-terminal extension containing two highly basic regions. The zinc finger core binds in the DNA major groove and recognises the first three GAG bases of the consensus in a manner similar to that seen in other classical zinc finger-DNA complexes. The second basic region forms a helix that interacts in the major groove recognising the last G of the consensus, while the first basic region wraps around the DNA in the minor groove and recognises the A in the fourth position of the consensus sequence [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.0016 9.4 7.4 0.0 20 45 74 99 65 105 0.84

2 7 0.065 3.8e+02 2.2 0.0 22 51 122 151 119 155 0.87

3 7 0.035 2e+02 3.1 0.1 27 48 159 179 151 185 0.83

4 7 8.1e-05 0.47 11.5 0.2 20 43 208 231 201 235 0.84

5 7 0.0077 45 5.2 0.1 13 45 229 261 226 264 0.90

6 7 0.1 6.1e+02 1.6 0.3 22 45 266 289 263 292 0.88

7 7 7e-06 0.041 15.0 0.1 21 45 293 317 290 322 0.86

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.0016	9.4	7.4	0.0	20	45	74	99	65	105	0.84
2	7	0.065	3.8e+02	2.2	0.0	22	51	122	151	119	155	0.87
3	7	0.035	2e+02	3.1	0.1	27	48	159	179	151	185	0.83
4	7	8.1e-05	0.47	11.5	0.2	20	43	208	231	201	235	0.84
5	7	0.0077	45	5.2	0.1	13	45	229	261	226	264	0.90
6	7	0.1	6.1e+02	1.6	0.3	22	45	266	289	263	292	0.88
7	7	7e-06	0.041	15.0	0.1	21	45	293	317	290	322	0.86

Coding Sequence: ATGGCAAAGAAGGGACGAATCAAACTCGACGACGGCCCGATTGAAATCGACGACAATATCAGTAATGTGATATTAATCGAAGATAGTCTCGATAGCGTTATCGACGTTGACCTGCTTGACCCCAAGCAGGAACCTTTTTACGGCGATTCACGATGTCCAAAATGCGGACAAAAGTTCGAAACGAACGACGAACTTACCTCGCATACTAAAACGTCCGAGTGTTCGGAAATCGAATCGATTTGCCATATCTGTATGAAAGTCATTGGCGGACATAATAATTTATTGAATCACATAAAAACTCACGAACTTACCGAGGACGAACCGATCGAAGTGAAGGACGAAACTACATTGCCGGAAGATGACGAGGATGAAATGAAATGTCCTTTTTGTGGTGAAGGCGTCGGAGACGGCATGGACTATGAAAAACATCTTCATATTCACGCATTTGCCGATTCTTCAGGTACACGATTTCCGTGTCTAATTTGCGGAAAAGAATTTAAAACTCGAGGCGATCTACGCCGCCATATGCTACGCCACGCCAACATAAAACCATACAAATGTGTCTATTGTCGTAAAGGTTTTGTTACGAAAAACGAACTTCAAACTCATGTACGTTCTCATACTGGTGAACATCCGTACGTATGTGATATATGTTATGCCAGCTTTACAACGTCCAGTTCGATGAAGAAACATCGAAGTAAGCATACGGGCGAAACACGATATGTTTGCTATATTTGTTCGAAAAAGTATTTCGATTCGTACGCACTAAATCGACATATTATGATGCATACGGGCGAACGACCATACCACTGTACCGTTTGCAATCGGGGTTTTTGTCAACGAGGCGATATGCGGGTTCATATGCGGATACATACTGGTGAGCGACCGTTCGAATGTCCTATATGTTTCGTAACATTTAAACAGTCGAGCAATAGAAATGCACATTTTAAAAGGCACGCGAGTCAAATGTAG
Protein Sequence: MAKKGRIKLDDGPIEIDDNISNVILIEDSLDSVIDVDLLDPKQEPFYGDSRCPKCGQKFETNDELTSHTKTSECSEIESICHICMKVIGGHNNLLNHIKTHELTEDEPIEVKDETTLPEDDEDEMKCPFCGEGVGDGMDYEKHLHIHAFADSSGTRFPCLICGKEFKTRGDLRRHMLRHANIKPYKCVYCRKGFVTKNELQTHVRSHTGEHPYVCDICYASFTTSSSMKKHRSKHTGETRYVCYICSKKYFDSYALNRHIMMHTGERPYHCTVCNRGFCQRGDMRVHMRIHTGERPFECPICFVTFKQSSNRNAHFKRHASQM

Sequence clustering based on sequence similarity using MMseqs2