Btry000860.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bactrocera tryoni
Gene Symbol
MBD-R2
Assembly
GCA_016617805.2
Location
NC:25431453-25435675[-]

Transcription Factor Domain

TF Family
MBD
Domain
MBD domain
PFAM
PF01429
TF Group
Unclassified Structure
Description
The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 1 8.7e-21 2.4e-17 61.9 0.1 4 76 410 480 407 481 0.93

Sequence Information

Coding Sequence
ATGGGGCGTCGCTGTTGTGTAACTGGCTGCAACTCTACCTCTCGTTTACCGGAACATCATGGTGTCACTTACCACTCGTTTCCCTTGGATGCAAACATACGTGCTATTTGGCTGCGTAATACCCGGCTTAGCTCAGAACGACAAATAACCAAAAGCGTGCTTGTGTGCTCGAGACACTTTCGTCGTATCGATTTCCAACCACAACGTAGTGGAAAGTATCTACTTAAACAACGCGTATTTCCCACAGTATTTCCGTGGGGAAAAGTCGATCCAACACAAGTTGAATCTGATTTAGAAGACCTAAAAAATAATAGCATGAATACATCAAGTCTTACAAGTCAATCAACGGAGGATGCTACGAAAGCAACAGTAGAAGCCAAGGttgcacaaataatggctgAAACTGCCGAACGTAGTGCAGCAAAAGCTAATGCCAATGCCGTAAAGGATGATGTTGAAAGTGCATCGCCAGTAACTACGCCAGTTGCTGTATCGCCGGCTGCTATTAAATTTGAGCCTGTCACGTCATTCAATCCCGGTGCACGATTAGAAGCACAAGATTTTGATGGTGTATGGCATGCAGCACGTGTGGTTGAAGTTGACAATGATGACAGAGAAGTGCTAATAAAATTCGAACGTTCTGGGAAAGTAAAATCGGCAGTTGTCGGTACAGAAGAGTGGATTCCCATGAATTCAACGCGTTTGCGACAAAAAGTTTCAACAAAACCAGTACCAGTTTTTGAATTGGAAGAAAAGTGTATGGCACGTTGGTCGGGGCCAAGAAAATTCCCTGGCACAATTAAGAAAATACTCGGAAATGATATGTATGAAGTACTCTTTGATGATGGATATGTAAAAAATGTACGTGCAgtacatattaataaaatattaccaTTGGATCCAGAGTTACAAGCACCAATATCATCATCTCCGACTATACCAAGCACTCCACAGACACCTTCAACCAATTTGTCAGACACATCAGCACTAAAAACTCCAAATACCGAATCGCCATTACCAGTGACGTCAAGTTCAACAAGTGGAAAGAAACGAGCTTCATCTGGTTCTCGAAAAGATTGGCCTTTACTTGATCTGGCAAAATTGGATTTATCTACATTAAATTTACCGGACATTCCAAAGGATGGAGAATGGACATGTCATTGGGTAAACGATCAACCAATTGGGAAAGAAGGTTATCTTATTGTCGGTGAGCACCGAAAGCCAACAGTAATCGTTGAAGATTGGCGTCTGCCACCAGGTTGGGTGAAACATATGTATCAGCGTTCAAATGTCTTAGGCAAATGGGATGTCATATTAGTTACGCCAGGTGGAAAACGTTTCCGCTCAAAAgctgatttgaaaattttccttgAGGAGCAAGGTCAGGTGTACAACCCCGATATATATGATTTTAGCATTCATCGACGCCGTGCAAAGGATATAAACGCCTATGTGTATACGCCTGACTATACGCCACAGCCACCGCCAAAACCAAAAGCGCTAGAAACGACAATTGCCGCCATGGATGCAGCAAGTGTGAAAGCAGCTACAACAGCACTTGCTGTCAGTACTTCACAATATATTGAAACACCCGTGGCCTCAGCCGAACCGCCTGCAGAATTGATGACACCAACTTTGGCAAGAGACTCTCCTTTGAAAGACGTCACAATGGATATAACAGATAATGCTGACACCGTTTCGGGACGCTCAGTGGATGCTAATTTGCCAGCAGAAGATGGTTATGcTTACATAGGGGGACTAAAGGTGCAAATAATCAATAACCTTTTCCGTTGTCCACAAGAGGGGTGTTTAAAGAACTTCCGCAAGGAGGATCACTTGCAAATCCATGTTAAGCACTATCATCCGGATTTGAATAAGCTTCTCGGTTCGTGTCCAAAGATGCTTGATCTGGCCGAAAAACGTACACATACCAAACCAGACCAACATGAACCTGCTCCGCGCAATCAAATTCCAAATCAGCAATTCTTTGCTAAGCTACATCAACAAGATTTACTACAAACGCGCGCACATAGACGTAGTGCTGGTGCACATGCCACAACCACTGGCGGTATTCCTCAGTCTACGGTGACTACGACAGATTTAAAATGTGAAGTCGAGAACAAGATGGAAACAGACGCTGATGCAGAGACTTCACAAATATCTGTCGGTCTCAATGACACCTTGCTTAATAGCTCGGCACAAGATAGTCATAATAGTACAGCGGTAGAGGCTGCTGTGGGCACTTCCATTGCAATGGATGATAGTTTGTCCGACATTCCAGGCATACCAACTAAACGTGCGCGCATGTCACCGAACAAGCGTACCCTGGGATCACGCAAAAGTAACCGTCAGCGCACCACTAAGCGATACTTGACAGCGGCACAAACCACAGCAGGTACATCGCTGCTACCGGTTGTCACCGGTGATAATAGTTTCGGTGTGTCCGATTTCGAGGAGACTCGCCACTCATTCAACGCCACTCCGGACGCCAAAGTTGTAGAGGTTGGCAAGAAACGCAAATCCTCTGGCGCGCCAGTCACATCAATGAGCAGCCTTGATTCACCGGTAACCGCTGACTCGGGATCGTCATCGTTTCCACCGCTATTGGCGGCTTCTAATGAAATTGATGGCATAGCTGGTGCAACCAGTGTAAATAATCCGCAGTACATAAAGGAAAACGGCGAAATAATAAAGATTGTTAGCATGCGTCAAGaggaaataataaattgtttatgCTCATATGGCGAGGAAGACGGTTTAATGATACAGTGCGAACTATGCTTATGCTGGCAGCATGGCATATGCAATGGCATTGATAAAGAGGTGGATGTGCCTGAGAAATATGTATGCTATATTTGTCGAAATCCACAACGTGGTCGCGAATCAATGCGTTTCAAGCACGATCAGGATTGGTTATATGATGGAAAATTACCAGTGGCCAATTACCACATTGCCAATCCAAATCTGCCAAAACGTTTCGAATTCTTGAAGAAATCACATGTTCTCACTGGAAATCTGGTAGAGTTAAATCGCTTTATGCATTCGTTGCGCGTAAAAATGAACATTGTCAATAATCGTTGTCATCCGAAATTGTATTTGTGGGCTAAAAAGTGGGAGGAAGACATAGCGCAGCAAAGTATCAAATCCGATATAAAATCTGATCAAGATATTAAAATCGAGGATGCCGAAATTGGCAGTAAAGTGTTGGGTGCAAAAGTGTCGCccattaagaaaattaaatcgGAGCCCACTACACCCACACCAGCACATCCCATTCCCAATATACCACAACCGGAAGCACCTATCGATCCAGTAGAGTGTCAGCACCGATTAATGGAGCATATTAAAATACAACAGAATTTGGTATTGAAACGTTTGGACGATATTGAAAACGAAATAGATGAACTGGAAAGTCAGGAtgatttaatcgatttaaaaGACGCCGACTATAAGAGTACGAAGGATGTTTTGGCCACTTTCATCAAGGAGTTGGATGTCATGAAGCAACTAGCAAAACTAAATGCTTTGGAgaatacaaaacaaacaatGAAAAATGCCGTAACTGCGAAGTAA
Protein Sequence
MGRRCCVTGCNSTSRLPEHHGVTYHSFPLDANIRAIWLRNTRLSSERQITKSVLVCSRHFRRIDFQPQRSGKYLLKQRVFPTVFPWGKVDPTQVESDLEDLKNNSMNTSSLTSQSTEDATKATVEAKVAQIMAETAERSAAKANANAVKDDVESASPVTTPVAVSPAAIKFEPVTSFNPGARLEAQDFDGVWHAARVVEVDNDDREVLIKFERSGKVKSAVVGTEEWIPMNSTRLRQKVSTKPVPVFELEEKCMARWSGPRKFPGTIKKILGNDMYEVLFDDGYVKNVRAVHINKILPLDPELQAPISSSPTIPSTPQTPSTNLSDTSALKTPNTESPLPVTSSSTSGKKRASSGSRKDWPLLDLAKLDLSTLNLPDIPKDGEWTCHWVNDQPIGKEGYLIVGEHRKPTVIVEDWRLPPGWVKHMYQRSNVLGKWDVILVTPGGKRFRSKADLKIFLEEQGQVYNPDIYDFSIHRRRAKDINAYVYTPDYTPQPPPKPKALETTIAAMDAASVKAATTALAVSTSQYIETPVASAEPPAELMTPTLARDSPLKDVTMDITDNADTVSGRSVDANLPAEDGYAYIGGLKVQIINNLFRCPQEGCLKNFRKEDHLQIHVKHYHPDLNKLLGSCPKMLDLAEKRTHTKPDQHEPAPRNQIPNQQFFAKLHQQDLLQTRAHRRSAGAHATTTGGIPQSTVTTTDLKCEVENKMETDADAETSQISVGLNDTLLNSSAQDSHNSTAVEAAVGTSIAMDDSLSDIPGIPTKRARMSPNKRTLGSRKSNRQRTTKRYLTAAQTTAGTSLLPVVTGDNSFGVSDFEETRHSFNATPDAKVVEVGKKRKSSGAPVTSMSSLDSPVTADSGSSSFPPLLAASNEIDGIAGATSVNNPQYIKENGEIIKIVSMRQEEIINCLCSYGEEDGLMIQCELCLCWQHGICNGIDKEVDVPEKYVCYICRNPQRGRESMRFKHDQDWLYDGKLPVANYHIANPNLPKRFEFLKKSHVLTGNLVELNRFMHSLRVKMNIVNNRCHPKLYLWAKKWEEDIAQQSIKSDIKSDQDIKIEDAEIGSKVLGAKVSPIKKIKSEPTTPTPAHPIPNIPQPEAPIDPVECQHRLMEHIKIQQNLVLKRLDDIENEIDELESQDDLIDLKDADYKSTKDVLATFIKELDVMKQLAKLNALENTKQTMKNAVTAK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01562944;
90% Identity
iTF_00193607; iTF_00191400; iTF_00192814; iTF_00190671; iTF_00190710; iTF_00192854; iTF_00191360; iTF_00189996; iTF_00189953; iTF_01563775; iTF_01563819; iTF_01562944; iTF_01562894;
80% Identity
iTF_00193607;