Basic Information

Gene Symbol
-
Assembly
None
Location
JAPVRH010001154.1:22625-25001[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 0.29 22 6.0 1.5 2 23 181 203 181 203 0.90
2 14 6.1 4.7e+02 1.9 0.1 5 23 211 230 208 230 0.85
3 14 0.29 22 6.0 0.6 1 23 236 258 236 258 0.94
4 14 0.003 0.23 12.3 0.4 1 23 282 304 282 304 0.98
5 14 0.0044 0.34 11.8 1.5 1 23 306 329 306 329 0.96
6 14 0.0001 0.0077 16.9 1.4 1 23 350 373 350 373 0.98
7 14 0.00038 0.029 15.1 4.1 1 23 389 412 389 412 0.98
8 14 0.28 22 6.1 0.4 2 23 474 496 473 496 0.93
9 14 0.0073 0.56 11.0 0.2 2 23 505 526 504 526 0.94
10 14 0.0033 0.26 12.1 0.8 1 23 532 554 532 554 0.97
11 14 3.1e-06 0.00024 21.7 1.9 1 23 559 581 559 581 0.97
12 14 0.0026 0.2 12.5 3.2 1 23 587 609 587 609 0.98
13 14 0.0011 0.085 13.6 3.1 2 23 615 636 615 636 0.95
14 14 0.018 1.4 9.8 1.3 1 23 641 664 641 664 0.97

Sequence Information

Coding Sequence
atgcactGCCGTGCTTGTATGCAAGTGGAATGTCATACGGttgtaaatatgaaacatGCTGCATCTGCGAAGGATAGTAAAACTTTATACGATTACTTTAATGAGTGCACTCAACTACAAGCAACATCGAATGATGAACTCCCACAAGTATTATGCACAAATTGCATAGAAGACCTACATAATgcctataattttataaagaaggCTCGCAAGTCAGATGGAGAACTTAAAAAGATTTTGACATCACAAAAAGGAAGCATAGACATTTATACTACTACTGAAAGTGCACAGTCTGTAGTGAAGTGTACAAATGACCCCTTAGCGACGccagaacaaaaaatttctgtaaCTGCAACTTCCATCCCTGGTGGCGATACTGAAGTGGCTATATCTTCGCCTGAAATAAAAGTAGAGCTAGATTTTTCagaagattttgaaaaaataattgaggATCATGTTGTGAAAAGTGATTCCGAATCTTCACTGCAAGGTGACAGTGATGATAACAGCGGTGACATTATCAAGCCTGGAGTATCTAATTCTTGTGAATTATGcgattgtacatatttaacgCAAAAGGAACTCAAAGATCATATATTTGATCTacacaaatCTCATATAATCTGCATAAAATGTCCGAAAGTATACGAGCTTCCCATGGAACTACATCTTCATGAATCTCTTGTACATAACACGGAATCACCATTTCAATGTATATGGTGTAATGAATCTTTTCAACGTGAGGATCTACCTAAACATATTCAGAAGAAGCATAAGAATtcgtattcaaaatattttccgcgAACGAGGAGCCGTTGTAATGATAATGATGACAAAAATAGTTTTCGATGTGATGACTGTCAAATACAATTCTCATCTATACTTGAGTTAGCCTATCATGTCAAGAAACACAAATTTGACTGTCCATTATGCTTGATGAGTTTTAGAAAACATGGTACGTATAGGGCTCATGTTAAACGCATACATAATCATTCCATAAGTAGCTTAAAGGCTGCGGTTGGTGTTGAGGATGATACAAATAAGCCATTCAAGTGTTCCATATGCTCCAGGCAGTTCAGATTAAAAGTGTCTCTTCAAGGACATATGAAAATTAAGCATAACCAGTACACACGCCAAAATGCAAAACACGACGAGGATAAGCTATTTGAATGCACAGTATGCAATATGCGTTTTGCAAGTCAAAATTCACTTTATCATCATAAAAGACGGAAACACCGAGATATGACAGCAACACCTGTTGTAGATAGTGAAAACGGTACTAGCGCAGTGGAAATGGGAAAAGATACAGAAAATAGTGGATTTGTTAATTGTACATTTTGCCATAAGGACATACCAACAATTCAAATAAAGTATCACGAAAGGCGACACAAATAtgccttaaataaaaaaagaacatttttgtgtgcattttgtcctcGTGAATATAATTCTGAAACTTCGGTTAAATTGCACGAAAAAAAGATTCATATGTGCGAGAAACCCGAACCCAAAGAATGCCCAATATGTCAGAAAAAAGTTgatccgaaatatttaaaaaaccacATTGAGAATGTTCACACGTCCGAACGTAAATTTATCTGTGATATTTGCGGTGATCCTTTCAAGAGTTACGTTTTGCTGCATAGCCATAAACGTTTGCACTTGGAGCGAAATTTCGCATGCACTGTGTGCGAGAAGAAGTTTATACGCTCATGCGatcttaaaatacatatgcgcATACACACAGGAGAGGAGCCATATGCTTGTCATTTGTGTGATcgaagatttaaaattaaagttcgaCTTAATTATCACCTGCAGCGTCATGCTGGCGTCAAGCGAAAATGTCAGGAATGTGGGAAAGAATTCAATCATgttaaacaattgaaaatccATTCATATAAACACACTGGCATGCCATACAGATGTGCTGTATGTGAATACGGTTGTGCACAGCGTGATGTatttcgGAAGCATTTATTACGTATGCATGATATGACTATGACTGACGAGGAGTATTGTGCAATGTTCAAAGCCAATACTGGCCGTAATCCGCATGTGAAGACTCTGGAAGAATTGCAATCGGAGACGCAAAATGTAGAACAAGACCAATCAAgctaa
Protein Sequence
MHCRACMQVECHTVVNMKHAASAKDSKTLYDYFNECTQLQATSNDELPQVLCTNCIEDLHNAYNFIKKARKSDGELKKILTSQKGSIDIYTTTESAQSVVKCTNDPLATPEQKISVTATSIPGGDTEVAISSPEIKVELDFSEDFEKIIEDHVVKSDSESSLQGDSDDNSGDIIKPGVSNSCELCDCTYLTQKELKDHIFDLHKSHIICIKCPKVYELPMELHLHESLVHNTESPFQCIWCNESFQREDLPKHIQKKHKNSYSKYFPRTRSRCNDNDDKNSFRCDDCQIQFSSILELAYHVKKHKFDCPLCLMSFRKHGTYRAHVKRIHNHSISSLKAAVGVEDDTNKPFKCSICSRQFRLKVSLQGHMKIKHNQYTRQNAKHDEDKLFECTVCNMRFASQNSLYHHKRRKHRDMTATPVVDSENGTSAVEMGKDTENSGFVNCTFCHKDIPTIQIKYHERRHKYALNKKRTFLCAFCPREYNSETSVKLHEKKIHMCEKPEPKECPICQKKVDPKYLKNHIENVHTSERKFICDICGDPFKSYVLLHSHKRLHLERNFACTVCEKKFIRSCDLKIHMRIHTGEEPYACHLCDRRFKIKVRLNYHLQRHAGVKRKCQECGKEFNHVKQLKIHSYKHTGMPYRCAVCEYGCAQRDVFRKHLLRMHDMTMTDEEYCAMFKANTGRNPHVKTLEELQSETQNVEQDQSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00193042;
90% Identity
-
80% Identity
-