Basic Information

Gene Symbol
-
Assembly
GCA_000789215.2
Location
NW:725918-732036[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 17 0.52 29 4.9 0.0 1 23 112 135 112 135 0.89
2 17 0.0027 0.15 12.1 5.6 2 23 184 206 183 206 0.96
3 17 0.0036 0.2 11.7 0.1 1 23 321 344 321 344 0.94
4 17 0.027 1.5 8.9 0.8 2 23 394 416 393 416 0.94
5 17 0.002 0.11 12.5 1.5 1 23 470 493 470 494 0.93
6 17 2.9 1.6e+02 2.5 0.0 2 14 512 524 511 528 0.83
7 17 8e-05 0.0045 16.9 2.2 2 23 544 566 543 567 0.96
8 17 0.0029 0.16 11.9 2.3 1 23 654 677 654 677 0.96
9 17 0.32 18 5.5 2.5 2 23 687 708 687 709 0.93
10 17 0.00016 0.0093 15.9 0.1 1 23 750 773 750 773 0.93
11 17 1.1 60 3.9 6.7 2 23 823 845 822 845 0.97
12 17 0.00034 0.019 14.9 0.4 1 23 902 925 902 925 0.97
13 17 0.0097 0.55 10.3 2.9 1 21 977 997 977 998 0.94
14 17 0.0034 0.19 11.8 0.2 2 23 1056 1078 1055 1078 0.95
15 17 2.4 1.4e+02 2.8 2.3 2 23 1128 1150 1127 1150 0.94
16 17 0.015 0.84 9.7 0.2 3 23 1247 1268 1246 1268 0.95
17 17 0.21 12 6.1 1.2 2 23 1318 1340 1317 1340 0.96

Sequence Information

Coding Sequence
atggaTCAACTATTCATGTTCTCAAATGAGTATACAGAGGATGACGATAACAATGCTAAGGATGGTAACAATAAAGaggaagcaaaaattaaaagtgaaccTCAAGAAATTGTCAATGATGGTGAAGATGACAATAGCTACATAATGCCGGAATCCTTATTGCAACAAATGACAACAACGCGAGATGAAGATGGAGAAGCTGAAGATGATaacactatttttaattttgggaTTGAACCAACTGCGAAAACACGTTCCTTGTCGGCTATAGTGAAATCAACTTCTACAAAAAATCCTCAAGATGCGTTAATTAACTATGATATGGCCATAATGTATATATGCCCGGCTTGCGGTGCGGAATTCGATACGCAAAGCATTTGGAAGGGGCACATAAATGGAGTGCATGAATATAATACTCGGCGAGGATTAAATTTTGTACCGATAGATAAGTTGTATCACAAATGTTTAGAATGCAACAAACCCATTGCTATGCATGCaatggaaaatttgttaaaacataaatttactcATTTGCCTCATCGCTGTACTAAATGTAAAATCTGCCATCGACGTTATAAATATCGGCAGGATTTAATTGTACATTTGCGCTTATGTCATCGTGAAGATGTGATATTAATGATGCAAAGCGAAAAGACACCTGTGCCTAGGCATGAAAACAAGCGAGCATCAATCCCTGCAGTAACAAATGCTCAGTTAGAAATAAAGGACATAAAAGGAAATGCTGTTGATATTTTTGAGAACACATGTGATAGTGTTGAGGTAAAAAACGAACCATTTGATCCGGACGATCAGGACGCGGAAAGTTTGCTGGTACAATCAGGGAGTAAATCCAAATATCCACGAACCTCAATACTAGAAGATGCACTGAGTCGAAGTTCTTCACAAGTTTTCGAACAGAGACCAAGTGATGAAGAGAAACAATGtgaaaaacatatacaatatatttgccCAGTTTGTAATACGGAATTCATGACCAAGAATGAATGGCAGGAACATGTACAAGAAATGCATAACTTTTGCACAATCAGTGGGCTTGGGtttcaaaaacgttttaattCAACGGCTGAATGTATGGAATGCAACCGGATTTTGCCTGACAATGCAATAGACcaactgcaacaacacaaattttCACATCTTCCTTGCAAAACATGGTTACGTTGTAAGCTTTGTTTACGCTCGTTTATTACCTACAAGGATATAATAAAGCACTTGCTCAACCAACATCGGCTTGATGACGAACTTGACGCAGATATGGATGACAGCCAAGATTATCGTTCCTTTGACCCATACGCTGCGCCATCAAACGACTATGAAGAAGACCAGACGTTAGCTGAAGACCAACTTAAAGGCGATCTACGTGATATTTATGAAACACAAATAGATTATTTGTGTCCTAAATGTGGTAAAGagtttttcgaaagaaaaatgtGGAGAAAGCACATTGTTAAAGCACATCATTATACCGATTTGAAAACACTTTGTTTTGAGGCTGTGAACGAGCACCAGTTGCAATGCCGATTATGCGGTAAAGTAATCACAAATGCCTACGGTGTGCAAAACGCTCAACAACATTACTTTACACACTTACCACACAAAGCGTACATTCGCTGCCGCTTATGTGATAAATCTTATACAGATCGCAAAGGATTGGTAAAGCATCTTCGTAAAGTACACCATATTAATTCCAAAACGGCAGCGACAGCAGCATTAGCTAAAGGAAATAAGATCAGGCCACCTTTATTAGCAACATACCAAAAGTCCTCATCTGAACACGTGAGCATATCTCGTAAAGCACCTGTTAAAGAAATCGTTCGTCATAACGGCGTaatatttgagataaaattttTGGACGAAGATAGTAATGATAACACCTCGTTTGGTGGGAGAAATGTAGATGACACGCATGAAAATAGTTTTGCTATGCCCACAAGAAGACATGTGTGCTCGGATTGTTACTCAACCTTCACTACAGTAcaagaattacaaaaacataccCGAGAACAACATGACTTCAAAAAACCAAGCCAAACAAATGTCTGCGGTAGGTGTTATTGTACATTCGAGTCAGAAGAAGCGCTGCAAGACCATAAAATAAAGCATCATTCATCGGATGCTAGTGGGGGTaacaatgatgatgatgatttaCTCTTGGTACCTACTGGCAACGAGGAAGTTAAAATGAACACCGCTGATGATACTCcaaatattgaacaatatttctgTTATCTATGTCCTGCATGTGGTGAGGAATTTAAAACTCAATACGAATGGCGTCGTCATATAAACGACATACACTATTTCGATCGCAGATATGagttaaatttcaaacaaatcgaTAAATTTCATTTCCAGTGCTTGGAATGTAAGGAAATTGTGAACAGTGCTAAATTGAAAGGTCTGCAAGACCATAAATTTCGTCACTTACCttataagttatatataaaatgtcgGCTCTGCAGCACATGCTACAATCATAAACCTAATGTGGTCACACATCTGTGCACGCAACACAATTTTGCACATCCACGAAAATCGTCCAGCTCAAGCCCAGCTATATCATCAGCACCGCAAATGCGTAATACATATAACATGCAAGCAACTACTTCTAACATTTTCAAGCCTTTATCAACTGAAAGCCTCATTTCCTTACACAATGCAGTAGAACACGAAACAATTACCTATTATTGCCCGCAGTGCAATGAACCGTTTAACACACATGCCCTATGGCGTCAACATATCGTCACTGTACATGATCTTAACAGTCGACAAGGTTTGAATTTCCGCCAATTAGACGCACACCATTATATATGTTTGGAGTGTTATAAACGAGTCACAGTAACTCATACCAAGGGCGCTATAGGTCAACTGCAGTCGCATAAATTCCGCCATTTGCCGTATAAATCTTTCTGTTGTACCAAATGTGGCGGTGTCTTTGTGCGCAAGCAAATGTTCTTTAAGCATCTAAATCGTGCCACCAATAGATGTCCACTGATGGGCAATGAACGCGCAACACATCatgtcaaaacaaaaagttataagAACTCGGTGCGTAATATATACGGTCAACAAAGTGACGACAGTAAACCGTTGAAGAATCTCAACTTCTCGGTGACATCGAATGAGAAGTGTCCCTACATCATACAATGTCCACAATGTGGCATAAAATTCGAAAAGTGGCATCCATGGCGTGATCACATCGAAAAGGAACACAAGCTAAATAGTATGGAatcattgaaattcaaaaagatCAATGATCACCTACACATTTGTATACAGTGTAAGGAACGTGTGAACGGTGCAAATTTTGTTAACCTCCAAACACATCGCTTTAAGCACTTGCCATATGGCACTTATTTACACTGTCGTTTCTGTGATGTCAGATACTATTATATGATTAACATTATAAAACACATGAAACAAAAACATCCAAATCATGGCCTGGAAGAGCTCGAATTGCAATTGGAGAGTGCACCAGACGAAGAGTCCGTCAGTTCTTCGGCGGTGACAGTGAGTATGGATGTTGATAAGGAGAGTGATGTGTGCGAGGAGAAAAACGCCGATAACGATGGTAATGATAATAACAAGACAAtcgacgatgatgatgatgcgcTGGTTATTGCTGACGATGGCGAACACAATAATAAAGTTTCTGAAGAAAAGGATATTGATTATGGTTTTGGGTGTGAGTCTtcaatatgttcatatattataCTATGTCCACAATGTGGTATTAAATATCATAATTGGTATACGTGGCGTGATCATATATCAGAAGCCCATTCGCTAAACAGCCACAAAACGTTGAATTTCACGAAAATTTTCGATTGGTTGCAAGAATGCAACGAGTGCAAGGAGCGTGTAAATGCCACATCGCTATTTAATTTGCAAACGCACAAATTCAAGCATTTACCATATGGCACTTACTTAGAGTGTCGCTACTGTGACGccaaatataactatataatacACATTGTTAGACATTTGAAGACGAAACATCCAGAGCATGCATTGCAAAAACAAGATAGACCCATTGATATTGATGAAACTTTATTGGACAATGTTGATGACAATGTTGCTGATGAAAATGTTGTAGAAGTAAAGCGCAGTGTTGGTGACGAAACAAAGCGTGTTACTAATTCGGATGGGGATGCAGAGGCTGAGGGTGATGAAGATGAGGATGTTGACGATGACATGGATGATGAAATTGATGAAGacgttgatgatgatgacgacgacgatgacgatgaagaAGAAGCTGAGGAGAATGCACATAATAATAATGGGAATGCTGCTGGTAAAGTTGTTGAGCAAATGGATGTTGATGCTAAAAGCGATGATGATTTTGGAGATGGtgatgacgacgatgatgatgatgatgatgacgatgatgatgatgatgatgacgatgatgatagTGAAAATTATGGTACTGATGGTAATGTAGAAGATCCAGCTATTGACAGCGAAAATACAAACGTAGAGGCGCCAAATGGTGTAGTGGAAGACATTGAACAAGTTGAAAACCCCGAAGAACAGTTTGTTCTTGGCTAA
Protein Sequence
MDQLFMFSNEYTEDDDNNAKDGNNKEEAKIKSEPQEIVNDGEDDNSYIMPESLLQQMTTTRDEDGEAEDDNTIFNFGIEPTAKTRSLSAIVKSTSTKNPQDALINYDMAIMYICPACGAEFDTQSIWKGHINGVHEYNTRRGLNFVPIDKLYHKCLECNKPIAMHAMENLLKHKFTHLPHRCTKCKICHRRYKYRQDLIVHLRLCHREDVILMMQSEKTPVPRHENKRASIPAVTNAQLEIKDIKGNAVDIFENTCDSVEVKNEPFDPDDQDAESLLVQSGSKSKYPRTSILEDALSRSSSQVFEQRPSDEEKQCEKHIQYICPVCNTEFMTKNEWQEHVQEMHNFCTISGLGFQKRFNSTAECMECNRILPDNAIDQLQQHKFSHLPCKTWLRCKLCLRSFITYKDIIKHLLNQHRLDDELDADMDDSQDYRSFDPYAAPSNDYEEDQTLAEDQLKGDLRDIYETQIDYLCPKCGKEFFERKMWRKHIVKAHHYTDLKTLCFEAVNEHQLQCRLCGKVITNAYGVQNAQQHYFTHLPHKAYIRCRLCDKSYTDRKGLVKHLRKVHHINSKTAATAALAKGNKIRPPLLATYQKSSSEHVSISRKAPVKEIVRHNGVIFEIKFLDEDSNDNTSFGGRNVDDTHENSFAMPTRRHVCSDCYSTFTTVQELQKHTREQHDFKKPSQTNVCGRCYCTFESEEALQDHKIKHHSSDASGGNNDDDDLLLVPTGNEEVKMNTADDTPNIEQYFCYLCPACGEEFKTQYEWRRHINDIHYFDRRYELNFKQIDKFHFQCLECKEIVNSAKLKGLQDHKFRHLPYKLYIKCRLCSTCYNHKPNVVTHLCTQHNFAHPRKSSSSSPAISSAPQMRNTYNMQATTSNIFKPLSTESLISLHNAVEHETITYYCPQCNEPFNTHALWRQHIVTVHDLNSRQGLNFRQLDAHHYICLECYKRVTVTHTKGAIGQLQSHKFRHLPYKSFCCTKCGGVFVRKQMFFKHLNRATNRCPLMGNERATHHVKTKSYKNSVRNIYGQQSDDSKPLKNLNFSVTSNEKCPYIIQCPQCGIKFEKWHPWRDHIEKEHKLNSMESLKFKKINDHLHICIQCKERVNGANFVNLQTHRFKHLPYGTYLHCRFCDVRYYYMINIIKHMKQKHPNHGLEELELQLESAPDEESVSSSAVTVSMDVDKESDVCEEKNADNDGNDNNKTIDDDDDALVIADDGEHNNKVSEEKDIDYGFGCESSICSYIILCPQCGIKYHNWYTWRDHISEAHSLNSHKTLNFTKIFDWLQECNECKERVNATSLFNLQTHKFKHLPYGTYLECRYCDAKYNYIIHIVRHLKTKHPEHALQKQDRPIDIDETLLDNVDDNVADENVVEVKRSVGDETKRVTNSDGDAEAEGDEDEDVDDDMDDEIDEDVDDDDDDDDDEEEAEENAHNNNGNAAGKVVEQMDVDAKSDDDFGDGDDDDDDDDDDDDDDDDDDDDSENYGTDGNVEDPAIDSENTNVEAPNGVVEDIEQVENPEEQFVLG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01564090;
80% Identity
-