Basic Information

Gene Symbol
-
Assembly
GCA_905475315.1
Location
FR997764.1:12561118-12570169[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 29 7.7e-06 0.0008 20.5 0.6 1 23 202 224 202 224 0.97
2 29 0.00056 0.058 14.6 0.3 2 20 256 274 255 276 0.92
3 29 0.0014 0.14 13.4 0.1 2 23 305 327 304 327 0.96
4 29 8.4 8.7e+02 1.5 0.2 2 14 344 356 343 363 0.82
5 29 0.0016 0.17 13.2 1.7 1 23 374 397 374 397 0.97
6 29 0.001 0.11 13.8 0.9 1 23 417 439 417 439 0.95
7 29 0.0018 0.18 13.1 0.8 2 21 479 498 478 499 0.94
8 29 0.002 0.21 12.9 4.6 2 23 538 560 538 560 0.97
9 29 0.0019 0.2 13.0 0.6 1 23 610 633 610 633 0.97
10 29 0.015 1.6 10.1 0.1 1 23 686 708 686 708 0.97
11 29 0.00084 0.087 14.1 4.0 1 23 719 741 719 741 0.98
12 29 0.0076 0.78 11.1 0.6 2 23 753 774 752 774 0.96
13 29 0.0026 0.26 12.6 1.4 1 23 784 806 784 806 0.98
14 29 0.0075 0.77 11.1 9.2 1 23 835 857 835 857 0.96
15 29 0.00038 0.039 15.2 2.8 1 23 868 890 868 890 0.98
16 29 2.1e-05 0.0021 19.2 0.5 1 23 898 920 898 920 0.98
17 29 0.00059 0.061 14.6 0.2 2 23 940 962 939 962 0.97
18 29 0.82 84 4.7 0.5 1 23 980 1002 980 1002 0.91
19 29 7 7.3e+02 1.7 4.4 1 22 1009 1030 1009 1031 0.75
20 29 0.015 1.5 10.2 4.0 2 23 1042 1064 1041 1064 0.95
21 29 0.025 2.6 9.5 0.2 2 23 1087 1108 1086 1108 0.95
22 29 1.3 1.3e+02 4.1 3.1 2 23 1151 1173 1150 1173 0.95
23 29 0.032 3.3 9.1 0.4 2 23 1189 1210 1188 1210 0.94
24 29 3.6 3.7e+02 2.7 3.8 5 23 1220 1238 1217 1238 0.93
25 29 0.012 1.3 10.4 0.8 2 23 1249 1271 1248 1271 0.95
26 29 0.05 5.2 8.5 2.3 2 23 1288 1306 1288 1306 0.92
27 29 1.1 1.1e+02 4.3 1.7 2 21 1310 1329 1309 1330 0.93
28 29 0.29 30 6.1 1.2 2 23 1379 1400 1378 1400 0.93
29 29 0.00064 0.066 14.4 0.6 2 23 1411 1433 1410 1433 0.97

Sequence Information

Coding Sequence
ATGGCTCTCAAGCTTGGAAAATGCAGGCTCTGCCTCAAGCTCGGCGACTTTTACTCGATATTTACGGTGGACAATGCCGTGCAACTTGCGGAGATGGCTATGGAATGCGCCCGGGTGAAAATCTACGATGGCGACGGGCTGCCAGACAAAGTGTGCTCGGAGTGCATACAGAAACTTAGCAGCGCGTACATCTTCAAACAGCAGTGCGAGCGCGCCGACCAGGAGCTACGGCGCAACTATGTGCCGCCTCCAGGGTTTAGTATCAGCCCTACACCACCAACAAGACAAAGCAGCGATTCCGCGTTTTCAAATCATACCGATAGCTCCAACCTAACTAAACAGGTGTCTTCCTTCGAAGAGAAAGGATCTCCCGTTACCAAAAGTAGGAAACGCAGCATCGACAGCGGGGATAACGGCTCCATAGGCGGCGCGTCTAGTGACTACAGACCCAGCGGCTCCAAACGTATCGAGGAACTAAGAAGGTTACAGAAAAGGCCACGGATGCAGTCCGGGAACACGTCGCAGTTGGACTCGGATTACGAAGACAATAGCGCCTCATACGCCCCGGAAACAGATTCCGACGAACCTCTACTCAGAAACAATTTCGACTGCAAAATATGTCCTAAACAATTCACAAGCAGACGAAGCCTCGCTAACCACGTACGAATACATGAAAAACTACAAAAAAAAGATGGTTTAGTAGGAAATGTCGTGGTCGAAATTCCGCAGAAGGTCGAGGATGCGGCTGACGCAGAAGATAAACTGAGCTGTAACAAATGTGGGAGGACTTTCAAACTGAAAATCATGTTGAATAGGCATTACGAGGTTTGCGGCAAGATTCCCGTCAAGTCACCGCAGAAGGAGCTGCTCGTGACGCTAGAACCTATTGACGGAATGATGAACAGGAATATTGTGTGTGAAATATGCAACGCCAAGTTCAAAGCTATAGAAAGTTTGGAAAAGCACATGAAAGTCGTACATGCGGCCGTTTTAAAACGAGAAAAACGTGAGAATAGTAAGGTGCCAGTTCCGTGCCTCTATTGCCACGAGATGTTCGATGACTACTACGCACATAGCGCGCATTTCAACGATTGTCCGCAGAAAGATGATTCCTTGCCATATGAATGTCCTGTTTGTAAAAAGCTTACGTCGAGAAAAACTTCGTACTTCCAGCATATTAAGAACATGCACTTTGAGCCTCGTTCGTCCTTCGCAAATACTTCAATAGAGGCAGAGCCTGAGACTTATCATGAATGTAGAATGTGCAACAAGAAGCTCTCTTCACAAGACTTGTTGATCAAGCATTTAGCTGCCCATATGTCGAATATTGAAGACAACGAAGTTGGCGCTGATAATGAGTCGCGAGCTAGCACTATCGAAGATTCTGCGTCAATCCAATCCATACACAGCAACTCCAATACTCCAGGTTGTATTAAATGCTCGAGGTGTGACAAAGAATTCAAATACAGGAAAGCCCTTCTCACTCACCAACTGAAATGTACGGAAGTGCAGGTGAAGGCCGAGCCCCCGGACAAGCCGTCCACGAGTCTGCTGAGCGAGGCCGCGTACCGCCAGTCCGATTCCGAGTCCAGCCAGGAGGAGGACGACAACACCTGCGACATCTGCGAGAAGCAGTTCTCCTATCGCCGCCAGCTGCTGCACCACAAGAAGACCAAACACAACATGAGTTCGGGACACAAGCGCGCCAAGATCTACCTCAAGGACTGCAAGGTCCGCTGCATGATCTGCGACGTAGAGATGAAGGTCGGCGATATCAACCAGCACAATCAGAAACACATTTCTAAGAACATGAAGCCCCGCAATCTCTACACATGCGCAGAGTGCGAGGATACCTTTAAAAGTTGTTCAGCGCTCGCGAACCATATAAAGCTGATACACAGGCTGAAGCAGAAGAAGCTAGAGCTGGGCGTCGACCCGTCGGATTTTTGTGAAGTCGTTGTGACAAAAGCGGAACCCCTGGACTGGATCCAGAGTCACAACGACTTTGGAGAGGTTCCGGGCGTGGAGACCAAGCCGTTGGTAGACCTTAGCGGCTTCACATGTCCTATCTGTGCCAAGAAAATGCCAACGCTCATATCTCTGAAGCGACACGTCAACTGGCATTCAAATGTTGGAAATAATATCGAGAAGAAGTATGAATGTGTTGTTTGCAATGAGGCGTTCAGATTCCAATGCCACTACAAGATCCACATGCGGGAGCACTACCACGACACGAACCTGGACCCGAAGCACCTGACGTGCAGCATCTGCGGGCGCGTGAGCAAGCACCTCCGCGCTGCGCAGGCGCACATGAACTTCCACAAGCAGACCCGCTTCCAGAACAAGGACTACCAGTGCTCCATCTGCGAGCGCGTCTTCCAGCACCGGAAGGTGTACCTCTCCCATATGGCCATACACTACAAGAAGGGCGACGTCGTCCACAACACCATTGTAGGCGACGCTTTACCCAACACGGCCGACAAGAACGTATTCGACGGTACACATAAGTGCCACCACTGCGGCAAAGTCTGCGATTCAGAAAACTCCCTCAAACATCATCTAATCTGGCACACGTCCAAGACATTCCTGTACGGCGCCCGACACGAGTGCAGTATTTGTAAAGTTAAGTTCACAAACAAAAGGAGATTAGAGCTACACATCAGGTCCCATTACGAAGATGATAATGGACCCTACAAATGCACCATCTGCGGTAAAGGGTACACTGATGAAGGCTACTACCAAAAACACGTCAAAGGACACAACTTTGATCACCAGTCTCACAAAAAGAGAATAGAAAATATTAGGAAGGATAAAGTCAAGTGCCCAATATGTTCTCGCTATTACCCAGATTTAGTCAAACTTATTCGCCATTTGAGGCGGACACATCCCGAAAGTAAGATGATCAAGACTGACCCCGACGCGCCTCCGCAGCCATACTTCTCTTGCAAACTATGCGCCAAAGTGTTCCTCGATCAACGCAGGCTACAGTATCACGAGGAAGCTCATCTCAGAAAGCCAGAATTCTTTAAATGTAAGTTTTGTGGAAAGAAAACCATATCACTAAAGAGTCATCGATTTCACATAAAGAGTCATTTGACGCAGAAGCACTTGGACAATCCACTGAAATGTTCTCACTGTGAGGAAACCTTTGTGAAGGGCTATGACTTGCACCACCACCTGCGTGATGCCCACGACATCAACGAGACGTGGATCGCTGAACGCACCGAACAAACCCTTAATGGCCCGTTAAAAGATCTGCAGTGCTCCATATGCATGAAAATCCTTGCAAGCAAAGGTAATTTTGAGCGACATATCGATTACCACAACTCATTAAGATGCAACTACTGCTTTGATTACTTCAGTTCACTTAGATTTTTGGAGGGACATCTAACCTTCTCGTGTGAAAAGAAGAAGCTTCTAGGTGACACCGAAGTTTATCCTAAGAAAGTGAAATGTGATATTTGTTACAAAGCATTCCACGTTCAAGTCAAACTAGATTGCCACTTGCGCACGCAACATGGGATCAAGGTGAACAAGGAAGCTTCGGCAGGGAAACAAGAGATCGTCTGCGACTTCTGCTTCAGGGTGTTCGAGAATGAGTACGCTTTATCTACTCATAAAACTTACCATCGTACTGTCGGCTTCTATGGATGCATTTACTGTAACAAGAAGTTCAACACAATGACGGTCTACCGAAAACACAAGAACCACCATTTCTCGCAGCTGAACGTGGACAACCCTACCAAGTGCGAACATTGCGACGAAACCTTCGTAGCGTTCAGGGAGATGATATACCACATGAGAGACGTGCACGGCGACGACAAGGAGTGGGTCATAGAGCCGAAGGAATCCATCGAGGAGACCTGCCCCATCTGCAACAAGGTGTTCTACAACCTGCACAAACACCTAAGCTACCACGAAGACAACAAGTGCAAAAAGTGCAGTGAGTACTTCTACTCCAGGGTAGACTACGATAACCATCTCTGTGCCGTTGAGAGCGATGATGAAGGCTTTCCAGCCGCTGGGACGAAGCAGGCGGCCCAGTACGAAGAGTGCAAGTTTTGCTTCAAACCCATCACAAAGAAGAGTTCCAAAGCCAAACATGATCAAATACACAAGGGATCTGGCTCTATTTCCTGTAGATTCTGTAAGCTTAAGTTTAAGACTATGGACGCTTTTAATATTCACGCCTTTTCACATCGAAGTAGAAAATACAATAAGAAGCCCATTAAATGCAGAAAATGTGGCGAAAAGTTTGTGAAATACGGACCGTTCATAAAGCATATGAAAACAGTTCATAAATCATTAAAGAAGCTGCACTACCGGGCTGTCGTGAAGCCCGAGACGTGCATCATATGCGGAGAGGACTTCCCCAACCTGCACAACCACTACCGCGCTCATATGTTGAACCAGTGCCACGATTGCTGCAAGTACTTCACATCCTACAGGTTATTCACTTTGCACGAATGTGACAAAGAGGACGCGGACCCATCGAAAGTGTTCACCAGCGACGCGAACCTGAACGAGTTGATAAACACGTACGTTCCTAAGGATGAGAAGGACGACGAGAAGTATTACGGCCACAGTGATGACGAGGAGGAGGAGGAGGAGTACGTGGAGCCGCTGGTGTATGCCGACGAGGAGAGCCAGGACCAGGAGCAGGAGACACAGGACCTGCCTCTCATGGCCCAGTCTCCAATCATATCAGATGTTCTGTCGCTGTACAAGCCGCAGACCAACGGAGTGGATGATGATGTCGTCAATATAACTGACGATGAGTCCGTCGACTTAGATCACGCCGCTCCAGTCGTAGTTATTGACGATGATGATGATTAA
Protein Sequence
MALKLGKCRLCLKLGDFYSIFTVDNAVQLAEMAMECARVKIYDGDGLPDKVCSECIQKLSSAYIFKQQCERADQELRRNYVPPPGFSISPTPPTRQSSDSAFSNHTDSSNLTKQVSSFEEKGSPVTKSRKRSIDSGDNGSIGGASSDYRPSGSKRIEELRRLQKRPRMQSGNTSQLDSDYEDNSASYAPETDSDEPLLRNNFDCKICPKQFTSRRSLANHVRIHEKLQKKDGLVGNVVVEIPQKVEDAADAEDKLSCNKCGRTFKLKIMLNRHYEVCGKIPVKSPQKELLVTLEPIDGMMNRNIVCEICNAKFKAIESLEKHMKVVHAAVLKREKRENSKVPVPCLYCHEMFDDYYAHSAHFNDCPQKDDSLPYECPVCKKLTSRKTSYFQHIKNMHFEPRSSFANTSIEAEPETYHECRMCNKKLSSQDLLIKHLAAHMSNIEDNEVGADNESRASTIEDSASIQSIHSNSNTPGCIKCSRCDKEFKYRKALLTHQLKCTEVQVKAEPPDKPSTSLLSEAAYRQSDSESSQEEDDNTCDICEKQFSYRRQLLHHKKTKHNMSSGHKRAKIYLKDCKVRCMICDVEMKVGDINQHNQKHISKNMKPRNLYTCAECEDTFKSCSALANHIKLIHRLKQKKLELGVDPSDFCEVVVTKAEPLDWIQSHNDFGEVPGVETKPLVDLSGFTCPICAKKMPTLISLKRHVNWHSNVGNNIEKKYECVVCNEAFRFQCHYKIHMREHYHDTNLDPKHLTCSICGRVSKHLRAAQAHMNFHKQTRFQNKDYQCSICERVFQHRKVYLSHMAIHYKKGDVVHNTIVGDALPNTADKNVFDGTHKCHHCGKVCDSENSLKHHLIWHTSKTFLYGARHECSICKVKFTNKRRLELHIRSHYEDDNGPYKCTICGKGYTDEGYYQKHVKGHNFDHQSHKKRIENIRKDKVKCPICSRYYPDLVKLIRHLRRTHPESKMIKTDPDAPPQPYFSCKLCAKVFLDQRRLQYHEEAHLRKPEFFKCKFCGKKTISLKSHRFHIKSHLTQKHLDNPLKCSHCEETFVKGYDLHHHLRDAHDINETWIAERTEQTLNGPLKDLQCSICMKILASKGNFERHIDYHNSLRCNYCFDYFSSLRFLEGHLTFSCEKKKLLGDTEVYPKKVKCDICYKAFHVQVKLDCHLRTQHGIKVNKEASAGKQEIVCDFCFRVFENEYALSTHKTYHRTVGFYGCIYCNKKFNTMTVYRKHKNHHFSQLNVDNPTKCEHCDETFVAFREMIYHMRDVHGDDKEWVIEPKESIEETCPICNKVFYNLHKHLSYHEDNKCKKCSEYFYSRVDYDNHLCAVESDDEGFPAAGTKQAAQYEECKFCFKPITKKSSKAKHDQIHKGSGSISCRFCKLKFKTMDAFNIHAFSHRSRKYNKKPIKCRKCGEKFVKYGPFIKHMKTVHKSLKKLHYRAVVKPETCIICGEDFPNLHNHYRAHMLNQCHDCCKYFTSYRLFTLHECDKEDADPSKVFTSDANLNELINTYVPKDEKDDEKYYGHSDDEEEEEEYVEPLVYADEESQDQEQETQDLPLMAQSPIISDVLSLYKPQTNGVDDDVVNITDDESVDLDHAAPVVVIDDDDD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00785388;
90% Identity
iTF_00185512;
80% Identity
-