Agaa000669.1
Basic Information
- Insect
- Autographa gamma
- Gene Symbol
- RHOBTB1
- Assembly
- GCA_905146925.1
- Location
- LR989871.1:8255042-8267694[+]
Transcription Factor Domain
- TF Family
- BTB
- Domain
- zf-C2H2|ZBTB
- PFAM
- PF00651
- TF Group
- Zinc-Coordinating Group
- Description
- The BTB (for BR-C, ttk and bab) [6] or POZ (for Pox virus and Zinc finger) [1] domain is present near the N-terminus of a fraction of zinc finger (Pfam:PF00096) proteins and in proteins that contain the Pfam:PF01344 motif such as Kelch and a family of pox virus proteins. The BTB/POZ domain mediates homomeric dimerisation and in some instances heteromeric dimerisation [1]. The structure of the dimerised PLZF BTB/POZ domain has been solved and consists of a tightly intertwined homodimer. The central scaffolding of the protein is made up of a cluster of alpha-helices flanked by short beta-sheets at both the top and bottom of the molecule [2]. POZ domains from several zinc finger proteins have been shown to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes including N-CoR and SMRT [5, 3, 4]. The POZ or BTB domain is also known as BR-C/Ttk or ZiN.
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 17 1.6e-07 6.5e-05 23.6 0.0 5 44 258 296 254 318 0.82 2 17 0.00067 0.27 11.9 0.0 16 44 320 347 316 369 0.80 3 17 0.00063 0.25 12.0 0.0 16 44 371 398 357 420 0.82 4 17 0.00068 0.28 11.9 0.0 16 44 422 449 419 471 0.80 5 17 0.00068 0.28 11.9 0.0 16 44 473 500 470 522 0.80 6 17 0.00066 0.27 12.0 0.0 16 44 524 551 518 573 0.81 7 17 0.00068 0.28 11.9 0.0 16 44 575 602 572 624 0.80 8 17 0.00071 0.29 11.9 0.0 16 44 626 653 623 674 0.81 9 17 0.00068 0.28 11.9 0.0 16 44 677 704 674 726 0.80 10 17 0.00064 0.26 12.0 0.0 16 44 728 755 722 778 0.81 11 17 0.00067 0.27 12.0 0.0 16 44 779 806 776 829 0.80 12 17 0.00067 0.27 11.9 0.0 16 44 830 857 826 879 0.80 13 17 0.00067 0.27 11.9 0.0 16 44 881 908 877 930 0.80 14 17 0.00064 0.26 12.0 0.0 16 44 932 959 926 982 0.81 15 17 0.0007 0.29 11.9 0.0 16 44 983 1010 979 1031 0.81 16 17 0.00028 0.11 13.2 0.2 47 109 1108 1177 1099 1178 0.76 17 17 3.6e-16 1.5e-13 51.4 0.1 6 108 1202 1303 1197 1305 0.91
Sequence Information
- Coding Sequence
- ATGGACAACGAGCAGCCCCACCAAGAGCTAGTAAAATGCGTGGTGGTAGGCGACACGGCGGTCGGCAAGACGCGGCTGATCTGCGCACGCGCATGCAACAAGCACGTGTCGCTGTCGCAGCTGATGACCACGCACGTGCCTACCGTGTGGGCTATCGACCAGTATAGGATATATAAGGATGTTCTAGAAAGATCATGGGAAGTCGTAGACGGTGTCAACGTATCTCTCCGCCTTTGGGATACTTTTGGAGACCACGAGAAGGATCGGAGATTCGCTTACGGAAGGTCCGATGTAGTCCTACTATGTTTTTCAATAACCAACCCTATATCACTAAGGAATTGTGGAGCTATGTGGTATCCTGAAATTAGACGTTTCTGTCCGAACACACCAATCTTATTAGTAGGATGTAAGAACGATCTTAGGTATATGTACCGAGATGAAACCTACCTCAATTATTGTAAAGACCGGAGCCCTTTTATAAGGGCACCAAGAAAAAGCGACCTAGTAATGCCCGACCAAGGCCGCGCTCTTGCGCACGAGTTCGGCATCTACTACTACGAGACCTCCGTCTTTACTTACTACGGCGTTAACGAAGTCTTTGAGAATGCCATCCGAGCGGCGCTCATGGCGAGACGGCAACAGAGGTTCTGGATGACCAACCTGAAGAGGGTGCAGAGGCCGCTGTTGCAGGCACCATTTAGGCCTCCAAGGCCCATGGAGCCTGAAGTAGCTGTCGTGAACAGCACTTACTTAGAAAACATGACCGTATTGCTAAGACAACAGTATTTCTCGGACATGGTGATTATCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTACGTATATACATGATAGGCTGCGGCGCTAAGGGCTTCCCGGTGCACCGGCTGATGCTGGCGGCGGCGTGCGAGGCCTTCCACCGCCTGCTCAGCACCGACTGCGGCTCGCTCTCCGCCGAGCTGGCGCGCAGCTCCAGTGAGAGCAGCATGGTGAGCAGTATGGGCGAGGCGACGACCGGCGAGTTCAATGAGGATACGGAGTACTTGATACGACAGGATCAAGCCAAGCAGATGAGGGTATGGGATCAGATAAAGCGGCGCTCGTCGTGTCAGATCCTACCGTTAAGCGACAGTTGTAAGAAACCGCCGGACTTGTATAGAGAGGTCAACCATCCCGCCATCATCTCTATTAGAGTTGTTAAGTGCGACAAAATCCAACACGCGACATCCCAAACTCAAACAATAGTGACGATGAGCAAGCTTATATCTCAAACAGTCATGCAAGAGATCATAAACTTCATATACACCGGCTCCTTAGACAGCAGTGCCTTTAAACAGCAGTCAGCTGCTATCGGATTGTTACTGGAGATACGCCAGGCGGCGGAACTGCTGGGCTTCCACGAGCTCACCAAGTTGAGCCAGTTCATCTTGGACCAACATCTACTGTTTGATAAGGGATTCATGCTGCAATTTCATACGCCTCTACCGCAGCGGCTATGCGACATGTTTGTGGAGCGCAGCATGTTCGCGGACGTGACGTTCGACCTCGACGACGGCATCCACCTCGCGCACCGCGCGCTGCTCATGGCGCGCTGCGACCCCATGAAGGCCATGTTCCAGGGACACTTCCGCGAGAGCATCTCTAGAGTGATATCATTCCCCGGCGTAAAAATGTACGCGTTCCACATCCTGCTGAGCTATATCTACAGTGACAAGATCCCGGCGGTGGAGCCCACGCGGTGTCTCGAGTTATTGGAGCTAGCTAACCGGCTGTGCATGAACCGCCTAGTTAACTTGGTGGAGGCGCGAGTTATAGACCAGTTGCAGCAGAGGGATAGGGTATGTGGTGACGATGATCAAGTCGTCGAAATAGCGTTGTCTCTACTCGAACCTGTCAAGTTGCACAACGCTCACAATCTGGCGGACTGGTGCATGTGGCGGCTGTGCGGCGCGTACGACCGCGTGTGTCGCGCCAGACATCTCTCACAGCCTTCCCGCGACTACCTCTCCGACAACCGCTGGCCGCCTGTCTGGTATGTCAAAGAGTTCGACTACTACCAGAAGTGTGTGAACGAACAAAGTAAAGAACAGAAGGAGTTAAGACCGACAACCTCATTACAAGCGAACCAACAGACTGGCTGCTTGTGTTTTACTAGCAAGACGCGGCGCGACAGCGAGCCGGGCGCTGACGTCACGACGGCGCTGTGCCGCTCGGAAGACGCCACGCTCGCGCTGCATCAGCCGCCGCTCTGA
- Protein Sequence
- MDNEQPHQELVKCVVVGDTAVGKTRLICARACNKHVSLSQLMTTHVPTVWAIDQYRIYKDVLERSWEVVDGVNVSLRLWDTFGDHEKDRRFAYGRSDVVLLCFSITNPISLRNCGAMWYPEIRRFCPNTPILLVGCKNDLRYMYRDETYLNYCKDRSPFIRAPRKSDLVMPDQGRALAHEFGIYYYETSVFTYYGVNEVFENAIRAALMARRQQRFWMTNLKRVQRPLLQAPFRPPRPMEPEVAVVNSTYLENMTVLLRQQYFSDMVIICGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVRIYMIGCGAKGFPVHRLMLAAACEAFHRLLSTDCGSLSAELARSSSESSMVSSMGEATTGEFNEDTEYLIRQDQAKQMRVWDQIKRRSSCQILPLSDSCKKPPDLYREVNHPAIISIRVVKCDKIQHATSQTQTIVTMSKLISQTVMQEIINFIYTGSLDSSAFKQQSAAIGLLLEIRQAAELLGFHELTKLSQFILDQHLLFDKGFMLQFHTPLPQRLCDMFVERSMFADVTFDLDDGIHLAHRALLMARCDPMKAMFQGHFRESISRVISFPGVKMYAFHILLSYIYSDKIPAVEPTRCLELLELANRLCMNRLVNLVEARVIDQLQQRDRVCGDDDQVVEIALSLLEPVKLHNAHNLADWCMWRLCGAYDRVCRARHLSQPSRDYLSDNRWPPVWYVKEFDYYQKCVNEQSKEQKELRPTTSLQANQQTGCLCFTSKTRRDSEPGADVTTALCRSEDATLALHQPPL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -