Basic Information

Insect: Atrophaneura dixoni
Gene Symbol: Baz2b
Assembly: GCA_018248015.1
Location: DWHX01001487.1:1993-32094[+]

Transcription Factor Domain

TF Family: MBD
Domain: MBD domain
PFAM: PF01429
TF Group: Unclassified Structure
Description: The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.3e-12 4.8e-09 37.3 0.0 3 75 642 717 640 719 0.88

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.3e-12	4.8e-09	37.3	0.0	3	75	642	717	640	719	0.88

Sequence Information

Coding Sequence: ATGGACAAGGAGAATGGCGAGGGTAGCGATGCCGCCGGCAAGCCGCCACCCGACGGCTTGCTGGACGCCGCTGGACTTTTCGGAGCATACTGGGGCCGCGAAAGTTCCAGTAGTGGAGCAGCggctgcgcaggcgcaggctCAGGCCCAGGCGCAAGCGCAGGCGGCGCTCTTCGGTTTCGGCTCCCGCTACCCACCGCCTACTACCCTCGGCGTTGCTGCCAACCAAGCTGCCTCACTTGGTCTCCACCCTGCAGCTAGCGCCGCGTGGTGGTCTATGGCGTCACATCTTGCAGCACAAGACTATCTAGCTCGCTTGCAAGCCTCCGGTCTCAATTTTCCACCTCTTGGAGACCCATACTCCGCTTTGTCGGCCTTATCCGGAGCCGGTGCTAGTATGAAACAACCGTCTAAACATAATAAGCAACCCATGCGGAGTGAAAGATCAGGTCGTAACAGTAGCGGCATGTCATCGAGCGCATCAATGAAAGAGAAGAGTCCATCAACAAGTGGTGGTAACTCTCAGCCGAGCATGAGTGAGTGGGGAACATCCTACGGCTTCCCGAAGACGTCTTCTCCGTCAACGATGCACTCCCAACCGTCTCTCTCAAGCCTAGCGTCTCTTAACAGCTTAGTATCAGCACCGCATCAATCCAAATCTTCCAGCAAGCCCCCACCTGTACCTACTTCATCCAGAAAGAGTTCGTCCAGTTCATCAAGCAAGAGTAAAGAGCGTGATTTGGCACTGTTAAGAGGCGACCTTATGTTGGCTCAAGCGGCGGCACACGGTGCCTATCACGCAGCCGTCGCCGCTGCCACCAAAGGAAAGaatatGTCACCGCTGTACCCGTTTGGCATGCCGGGTTCAGAAAAAGATCGACACGCAGGCATCGACACACTTACCGGTCTTCCGCATACCATACTtagtgCCGCTTTGGAAGGCGGcGACCCTTCGTCAGTGCTTGGAGGAGTTCGCCTTCCACCTGATacggaaattattaaatacaccTCATCGCTGGCAGGGCCCaagGTACCTCCAGGGACTACTAATCGGGGCCGCAAAAAGACGATATCACTGGATCCCCCTCAAGTGTCAGTCCATCCCTCTGCCGGCGATAGGTCGACGCCATTGCCAAGCAAGCGACCTAAAGTCGAGGATTATGGCAGCGGGCGATCGTCCGTCGAAGTGATTCGGTTGCCGGGCAAAGCGGAACGTGGCGGCGGCCCGCTGGCGGGTACGCCGCCACCCAACCTGGCTGACTACGCGGGCATATCACGCGAGCTCTTACAGACCATTGCCAGCCAAAGCGGGGTCAGCCTGGCGGCACTCGAGCGTCAACTGGCAGCACAGCCCGGAGATTCTGGTTTGAATTTGAGCACAAAATCTACAACATCGGATGATGCGCCACTCGACCTCGGCTTTAAATCTACCGCCGATGAAGACGCTCCCCTCAACCTGTCTCTGAAGCCTGCACCTCCAAGTACGCAGGCTTCTGATGCGTTGTCCCGTCTGACTTCTCTGAGCAGCTCTCTAAACGCTTCGAATAATGATAGAATATCGCGTAGAAAACCAGGTGCAAAACCGCGTCGGGTGGCACCTGAACTGAACTCTCACGCTGCAGATTCACCACGACCGAAGTCTAGTGGCAGTGAGGACAGCGAATCAATAGGCGGATGGCCTACACGCGAAGGCCGGCCGCGTAACTTGGGGCGCGGTGTGAGCAAGCCCAAGAAGAACACGGTGGCGTCGCTGCTCGCACAAAGTCGAGCGCTCGGCTTGCGACCGGCTCTCGCTCACCAACTGCTCGCTGAAACGGACTTAGAAAAGCTTCGGACGCTTCTTGGAGAAAGCGCGAGCACGGATTCGGAGTGTCCGTCAGACAGCGGCCCCTCTGACTCTGACGCGAGTGACCCGGGCCGTCGACACGATGCCCAGTTACGCTTACCACTCGCACTTGGCTGGAAGCGTATGACGGTGATCAAAGGTCTATCCCGTAACTGCAATATAAAGGGCGACGTGAGCTACTCACCACCTGAGCCACATTTAGGACTAACTATAAAGTCCACACAGGACCTCAATACgttcTTGGACTCAAACCCATGTCCGCCGTTGTCGTCGGACAACTTCAGCTTCAGCGCGCGCACTTTGCTGGGAGAATACGTACAACCGGCGCCGGATCTAGCGGAACCACTTATATTCAATGAAACCGAAATCACGAAAagATTGGAAGAAGCTAGGGCTTTAGCCGCGCTTAGTACACCGCGTCCGACACCGCCACCTGTGGAGCGTCGTATTGAACTAGCGCGGCGACAGCAAGCCGCGAGGGACGCGCGCAGGGATTCCGGGCCACGAAGAGAACAGGCTCGTCTAGTAAGAGAGTTAGAAAGGTCCGAAAGGGCTGAGCTAGCGAAAAGGGAAAAAGAGGTCCGAAGTCAGCAGCTATTAGAGCATATCAACAAGAACCGAACGCAGCTCACCATCGAACCGCTGCCGTCGATACCGAAAATTTGTACCGAGTCCAATGAATGGAAAATACCAGAGATAGTAATGGGTCCAGCCGTTAAAACTAATAAGGACCGCACTATGCCTCCAATAAGCTTATCCTTAATACCCGTCAGTGGACCGAAAGATCAAAATACAcctattaaaacaataaattttgatcAATCTGGATGGAAGGAAGAGATTGAAGAATATAACGCACTTGATAAAATGAAAGACTTCGCTGAAAAAGCGGCTTTCGATTTACCGAAACAgccaaaaaacaaatacttcgACTTTACATTGATGAAGACaactgaaaagaaaacaaatacacCTGATAAGGAGAATAATTTAGAGAAATTGATCGAGTCATATTCTAGAATAAGTGAGTTTATAAACGGCTGCGATTGGTCAAAACTAGACGGCGAAAATAAAGACGATCCAAAAAGTTTGgaacagaaatatttagacGCTAAGAATGAATTCATGTCTCAAAATCTGATGTTAATGCcaaaagaaacacaaaaatcAGTTCTAAAAGAGGTCATCGACCTAAGCGGCGATGACGAGAACATACTCAAcgatattattacaaaaaaaatcagtcaGGGGACATTTAACGTAGGCAAAGATGGTGCGCTGTCTATCTCAGTACATCCCTTCGGCAGTAAGGACATGTACTTGGCTAAGAGAAGAAAGCAAGAGGAATTAGAGAAGCAGAAAATAGAAGATCAGGCGAAAAGACAACAGgaGAGAGAGTTAAAAAGACAACAAGCTATCCTGTTAAAAGAacagCAAAAGTACATAACAGAGGAACGTGAGAGGAGACGTCAGCACACGACGTTTATTCGTCAACTAGAAGGACGCAGACGGTGGGCGGAGCGTGAACGTAGGAAGCATCAAAATCTCCTCGACCGTCTATTGGCTAAGGAAAGAAAATTGCAACAACGTAAAAAGGAGATGGAGTTGCTCGCGGAGCTCAGGAGACCTCAAGAAGACTCATCATTATCTGATCAGAAACCACTGCCAGCTCTTAATAGGATTCCAGGACTAAAGCTTTCCGGCCAAGCTATGGCAGACTTATTACAAGTATACGAGTTTATACACAACTTTGGACAGACACTTGGATTTgaCATGGAATCACTACCCACGCTACAGACTTTACAACAGGCGCTGTTGCCTGATTGTAGTGCTGACGCAGAGGAAGAACTGCTTCAAGTTCTTACGCAACTACTCGTTTGCTCCATTGAAGACCCAGGCATTCCACATCCTGGTCGACATACGACGCTTTTGGGCCATGCCATCCGTATGGGCGACATCACGCCCGCAAATCTCAGCGAAGTGCTCCGTATCTTCCTATACGCCAACGCTACTGGTGAACTCAAGTCACTTACTGGATTAACAGcagagagggaaagagagcGTCGAGTAGCAGATCATCATCAAAGCGACGCAGAAATGCAACACACGTGCGCTCACACCAAAAACGCAGCATACTATGAACAACTTCACAACAACCTCACTTATAAACTATCtgAGACACTTCGCGATAAGCCGTTCCTTGCGCTTAACCCGACTACAAAGGCGCGCATGTTGGCTTACTTGTGCGACGAGCTGCTTCAAAGTAAAGCTGTTCTGCGGCAAATCGACGCATCACTTGAACACCTCAACCAGTTGCGAAAAGAACGCTATCTCATGGACATGAAGATACGAAAagtGCGGGTACTTCATCAACGCAAGGTACGCTCCGAACAGGCGGAGAAGCAGCAGGCGCTAGCGTTGGAGCGCATGCAGCGCTTAGTAGAAGAGAGTACTACCACAGTCACCAACATTTCGCATCTACCGGAAGAAGatcATATAATAAGTGACAAGAATGAAACTCCCAAGAAACTTGAAAAAGCCGATTCACCACAGCTGGAATCAGAatctaataaacaaacagaacTGCCGTCCCCCTACAAAGATAACGTGGCGATTGAAGAAAGCGACAAAGAACTCTCACCCATAAAAGACTTAtcaaatagtattaaaactaaggagattttaaataacaataaagacGAATGTTCACCACCCGACAACTCGAAGATTGATAAAGACAGTGTTATAGGCGACTGTGATGCAATATTGAGCGACTTAGAAAGTGAGGGAACTCAACCGGAAGagGATGAAGATAAAAATCTTTCATCTGAAGAACTCGCACGCAAACTGgagaaactattaaaacaatcAGAACAACAAATGCAACAGCTCTCAGCTGGTTCGCACGCATTAAGAGCTACTTGCTATGGACAAGAcaggTACTGGCGACGATATTGGTCTCTAGGCAAGTGCGGAGGAGTCTACGTAGAGGCTATGGAGTCGGCTCAACCAGAAATTTTAGCCTACCAAGAAGCGTTAGAAACAGCTTCCCTTAAAGGACAGCCTTTGAGCGACAcagcaaagaaaaagaaaaaagGatcaaaagataaaaatgatataaaggAAGAAGTGGAAACTGAAGCGCAACGTCAAGAAGAAGCTTTACAAAGCGAACTTGAACTGCGCAATATAAAATCGGAATTAAACCTTAGTGATCATACACAGATTATTAAGTACGAGCCGAATGTAAAGCACGGCACGTGTAAAGTTGAAGGGTCATCTATAAAAAtggaagaaaaatatattcagcaaaaacaaaacaaagaagaAGAGGATCTGCTAGATATTGAGGACTCCATTCCCACCGCGTTTCTAGTCCAGAAACCAACTCACAAACCAATGTTCGCAACACAAGCAGAACCTATAGATAAGCCACAGGAGATCGTAAAAGTAGAAAATGTCGTAAAAGCAGAATCTGTGGAGAAGGAAGTAGCAGAAGAAAGTAAAGATgaacttgttaataatttagaagaattaagaaaaatggCCGAAGCCGTATCGTCGCAATTAGATGCTGCTAAAAAGGCGGAAGCAGAAATGAAAGATGAATATGAGGAAGCAGAGCGACTTACAAAAAAAGAACTATTGGATGCTGAAAGTGCTCACATGCAGCTTTACATGAAGATGATGGAAGGAAAGTGGTTCTCTATTTTGAGGCACGAAAGTTCATATTTGACAAATATAAACGAGGACAAATCACATGAGCAAAAAGTTCCAGAGTTCTGCAACAATGAGCACACTTGCTCAGAAGTCGTTATGAGCCAAGGTCATAAATGGgatgtttcaaataatttgcATTTGCTTAACGATCCTAGTCTATTTACTCTTAATAGTATGGTGACAAGTGTCCAGGTCCCAACCAATACTGTATACACAGACTCCAGTCTTACTATGTCTGGTTTGGCACAGGAAATGATGGACGCgagtataaataaagatgaGAATGACGAAGACGAGGAAATGGAGGAAGATAACAAAGAACAAGATAATGATCTAGAAAGAGAATTGCAAGCTGATTCTGCGAAGCTAGAAGCAGCGGCACAAAAAGCAAAGGCTTCTGGTCTTACTAGTTTAGGTCTCTTGAACTTCAATGCATTATCTACATACGTTACGTGCGACAGTCCACCGCCTATACAGATGACGCCCGACGAGGTGGAGCAGTTGGAACAATGTAAAGTGCATGGAATGCCGAAAAAATTGGAGGGCGGATTTGTGCCCAGAGAGATGCGacatGGTTGGTGGCGCATTAACGATACTAACGAGCTTACTGCTGTGATACGCGCCCTTCACCCTCGCGGAGTCCGCGAGCGTGAACTGTACTCTACGCTTACGCACAACCCGCAACAAATCACAGACAAGTTGCTCATGGAGAAAACTGAAGTAATACGTTTCGAGTCAGCACCTCCGGTTGACGAAAAAGTTGACCAAGATTATCCTGAACCAGATTCGCCGAGTTCCTTCTGCGCGATCACTGCACGTCGCGTTGATCTACAGTTATTATCAATGgTTGAAGCTCTAGAGGAGAGAGTAGCAGCGGCCTCAATGCAGGTAAAGGGTTGGCGGCCGTCCCGCTTGCCCCTGCCAGAAGAAGCTACGGGGGCAGAGATAGTGGCACGGGCAAGGCACAAGTTGGCTTCTGTGGAGGCTCACATCGAGAGGAGATACCTTAAACCGCCTTTGGTACAAAGGTATGCTAGtACCACAGAGGCTACTTTGGGAGCCGTATTACAAGGAGAGCACGGCAACGCATCGGCCACGTCACCTCAAAACTCTGAACCAAGTGAAGGCAAagATAATAAGGGAATAGCACGAGGTTTAGCAACGTGGCGTGAAGCGGTGGCACGATGTAACACGTCGGCGCAGCTGGCGATGCTACTGCAGGCTTTAGAAGCCGCCGTAGCTTGGGATAAAAGCATCATGAAAGCAAATtgtcaattttgtttatctggTGATAATGAAGATCAGCTACTACTTTGCGATGGTTGTGACAAGGGCTATCACACTTATTGTTTTAAGCCCCGCATGGAAAAAATTCCTGAAGGAGATTGGTACTGCTGGGAATGTGTGAACAAGGCGCGAGGGGAGCGTGTTTGTATAGTATGCGGAGGCGCTTCGAGCGGGCGCACCATCCCTTGCGCCCTGTGTGTACGCGCGTACCACCAGGACTGCCACTACCCGCCTCTGCAcaagaatCCTCGTGGCAAATGGTACTGCTCGCAATGCATTTCACGCGCACCTCCTAAAAAACCACGAAACGCAAAGAAACGCGAAAGTAAAAACAAGGATAACAGCATAGATCTCGATCAGAGTATGGTCCCGAGGTA
Protein Sequence: MDKENGEGSDAAGKPPPDGLLDAAGLFGAYWGRESSSSGAAAAQAQAQAQAQAQAALFGFGSRYPPPTTLGVAANQAASLGLHPAASAAWWSMASHLAAQDYLARLQASGLNFPPLGDPYSALSALSGAGASMKQPSKHNKQPMRSERSGRNSSGMSSSASMKEKSPSTSGGNSQPSMSEWGTSYGFPKTSSPSTMHSQPSLSSLASLNSLVSAPHQSKSSSKPPPVPTSSRKSSSSSSSKSKERDLALLRGDLMLAQAAAHGAYHAAVAAATKGKNMSPLYPFGMPGSEKDRHAGIDTLTGLPHTILSAALEGGDPSSVLGGVRLPPDTEIIKYTSSLAGPKVPPGTTNRGRKKTISLDPPQVSVHPSAGDRSTPLPSKRPKVEDYGSGRSSVEVIRLPGKAERGGGPLAGTPPPNLADYAGISRELLQTIASQSGVSLAALERQLAAQPGDSGLNLSTKSTTSDDAPLDLGFKSTADEDAPLNLSLKPAPPSTQASDALSRLTSLSSSLNASNNDRISRRKPGAKPRRVAPELNSHAADSPRPKSSGSEDSESIGGWPTREGRPRNLGRGVSKPKKNTVASLLAQSRALGLRPALAHQLLAETDLEKLRTLLGESASTDSECPSDSGPSDSDASDPGRRHDAQLRLPLALGWKRMTVIKGLSRNCNIKGDVSYSPPEPHLGLTIKSTQDLNTFLDSNPCPPLSSDNFSFSARTLLGEYVQPAPDLAEPLIFNETEITKRLEEARALAALSTPRPTPPPVERRIELARRQQAARDARRDSGPRREQARLVRELERSERAELAKREKEVRSQQLLEHINKNRTQLTIEPLPSIPKICTESNEWKIPEIVMGPAVKTNKDRTMPPISLSLIPVSGPKDQNTPIKTINFDQSGWKEEIEEYNALDKMKDFAEKAAFDLPKQPKNKYFDFTLMKTTEKKTNTPDKENNLEKLIESYSRISEFINGCDWSKLDGENKDDPKSLEQKYLDAKNEFMSQNLMLMPKETQKSVLKEVIDLSGDDENILNDIITKKISQGTFNVGKDGALSISVHPFGSKDMYLAKRRKQEELEKQKIEDQAKRQQERELKRQQAILLKEQQKYITEERERRRQHTTFIRQLEGRRRWAERERRKHQNLLDRLLAKERKLQQRKKEMELLAELRRPQEDSSLSDQKPLPALNRIPGLKLSGQAMADLLQVYEFIHNFGQTLGFDMESLPTLQTLQQALLPDCSADAEEELLQVLTQLLVCSIEDPGIPHPGRHTTLLGHAIRMGDITPANLSEVLRIFLYANATGELKSLTGLTAERERERRVADHHQSDAEMQHTCAHTKNAAYYEQLHNNLTYKLSETLRDKPFLALNPTTKARMLAYLCDELLQSKAVLRQIDASLEHLNQLRKERYLMDMKIRKVRVLHQRKVRSEQAEKQQALALERMQRLVEESTTTVTNISHLPEEDHIISDKNETPKKLEKADSPQLESESNKQTELPSPYKDNVAIEESDKELSPIKDLSNSIKTKEILNNNKDECSPPDNSKIDKDSVIGDCDAILSDLESEGTQPEEDEDKNLSSEELARKLEKLLKQSEQQMQQLSAGSHALRATCYGQDRYWRRYWSLGKCGGVYVEAMESAQPEILAYQEALETASLKGQPLSDTAKKKKKGSKDKNDIKEEVETEAQRQEEALQSELELRNIKSELNLSDHTQIIKYEPNVKHGTCKVEGSSIKMEEKYIQQKQNKEEEDLLDIEDSIPTAFLVQKPTHKPMFATQAEPIDKPQEIVKVENVVKAESVEKEVAEESKDELVNNLEELRKMAEAVSSQLDAAKKAEAEMKDEYEEAERLTKKELLDAESAHMQLYMKMMEGKWFSILRHESSYLTNINEDKSHEQKVPEFCNNEHTCSEVVMSQGHKWDVSNNLHLLNDPSLFTLNSMVTSVQVPTNTVYTDSSLTMSGLAQEMMDASINKDENDEDEEMEEDNKEQDNDLERELQADSAKLEAAAQKAKASGLTSLGLLNFNALSTYVTCDSPPPIQMTPDEVEQLEQCKVHGMPKKLEGGFVPREMRHGWWRINDTNELTAVIRALHPRGVRERELYSTLTHNPQQITDKLLMEKTEVIRFESAPPVDEKVDQDYPEPDSPSSFCAITARRVDLQLLSMVEALEERVAAASMQVKGWRPSRLPLPEEATGAEIVARARHKLASVEAHIERRYLKPPLVQRYASTTEATLGAVLQGEHGNASATSPQNSEPSEGKDNKGIARGLATWREAVARCNTSAQLAMLLQALEAAVAWDKSIMKANCQFCLSGDNEDQLLLCDGCDKGYHTYCFKPRMEKIPEGDWYCWECVNKARGERVCIVCGGASSGRTIPCALCVRAYHQDCHYPPLHKNPRGKWYCSQCISRAPPKKPRNAKKRESKNKDNSIDLDQSMVPR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00249723; iTF_01495795; iTF_01115721; iTF_01496624; iTF_01494328; iTF_01495065; iTF_00197383; iTF_01337769; iTF_00922894; iTF_01155214; iTF_01157809; iTF_01154000; iTF_00957970; iTF_00840314; iTF_00195188; iTF_00204373; iTF_01402740;
90% Identity: iTF_00197383;
80% Identity: -