Acin008877.1
Basic Information
- Insect
- Athripsodes cinereus
- Gene Symbol
- egg
- Assembly
- GCA_947579605.1
- Location
- OX388307.1:19265666-19286153[+]
Transcription Factor Domain
- TF Family
- MBD
- Domain
- MBD domain
- PFAM
- PF01429
- TF Group
- Unclassified Structure
- Description
- The Methyl-CpG binding domain (MBD) binds to DNA that contains one or more symmetrically methylated CpGs [2]. DNA methylation in animals is associated with alterations in chromatin structure and silencing of gene expression. MBD has negligible non-specific affinity for DNA. In vitro foot-printing with MeCP2 showed the MBD can protect a 12 nucleotide region surrounding a methyl CpG pair [2]. MBDs are found in several Methyl-CpG binding proteins and also DNA demethylase [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 2 0.11 1.1e+03 0.7 0.0 28 38 1242 1259 1206 1261 0.70 2 2 1.3e-12 1.3e-08 35.7 0.0 5 71 1292 1351 1288 1356 0.88
Sequence Information
- Coding Sequence
- ATGGATTCTTCTAATTCAACGTTGTCACCATCGATTGATGAAAAGTCTATTCTAGGAGGAGTTTCTGCTGAAGATATGCAAGGTAATGAGAAATCTGAGTCACCAAGTAATGAAAAAAATGTTATCCAAAGTTTGAATTCTAACATAAATGAAAATATACTCATGGATACAATAGAGTTTGATGAGAAAAATGTGACCACTTCTCACAACAACAGTGAAGAATTTGAAAGTATGACAGAAGCTTTCAAGGCAGCAATATCTGAGAAATCACCAAGCAAAAGTGATGTGGTCAATGCTGCAGAAACAAAGGCCGCTTTCCCTGCATTTGATTCCTTTGATGAAGATAGTTGTAATAAATTTGATGATCTTGAAAACAGAGTGCTAGGGATTCTGTCAGATATTTCTAGAGAGGAACAGGAAAATAGTAAACAAGAAACTAATGAGCAGGATGCAGAAGATAATGTGAGTGTAAACGAAACAACCTCTGCAACAATTTCTAAAATTCCTGAGAAAAAAATTGAGGATACAGACGATGTTTCAGTGGATTGTGACAATGATGGAGACACGTTGGGATTGTTGGCTGAAACTGAAGGACGGGAAAGACACTTTTCAGACCCTGAAGATGAGGATGATGAAGAGGAAGGGGATGGAGATGGGGACATTGAAATGGAAGAAGAACATCTTGAGAGTGGTATGGATAGTGATGTAGGTGAAGGGGACGATGAGGAGGGAGAGTACAGTAACAGTAATGATGGTGATGATGATTATAAACCCAAGTCGGATGAAGAGGAAGATGAACAAGATGATGAAGAGGAGGATGATAATGATCCAGAGCTCAGGACATATGTCAAGAGAAAGAAACTACTCAAAGACCTGCATCGACATACTTACCAACCATCTGATAGCAATGATACAATGGAATCTCAAACACCTTTCCAAACTGACATGGATACAGCTGAATCAAGAACGAGTGATGTTGAACCTGGGGAAATAATGTTCAGTTCAGTCAAAGAAGATACAAATAGTTTTAGTGTAAATGATAAACCAGTCTTGTCCATTTGTAGTGTCTCCAGTTTGGTGGGGAGTCTTCAGGATTCTCATTCTGAAGACAATAAAAGAGAAACTGAGACACTAAATCTGGGTAGTGATGTCTCCAAAGTATTAGATGGAGAAACTTTGCATCTAAAAGATTATGCTTCTCAAGAAGATAGTGCGAATATAATATCTAAAGATGTATCAGAAGAAATCATCATTGAAGAAGATAATAGTAAAAATATCAGCATGACTATTTCAACTGATATATCAACCAACATTGTACCTCAAATATTATCTACTCAATCAAAAAATGAAGTAACAAAAATGTCTCAAGAACAAGATGAGCCTTTGGTTAAAGTGAAAGAAAGTATTTCAGTAAATGATTCACCAAAAGATAATTTAGAAAGTGCTAAAGAAAATTTGGAAAAATATTCCCAATTGATGGATGTTGATGAAGATATTGTATCTGAGGAGACTAAGGATGCCATCAAAAGTGACAAATTGTTAGAGAAAGATTCTTCTACTCAAAAAAAAGATGATTCAACCAAATCAAGTGCTGAAATAATTGAACAATTGTCTGATACTTATAATGAAAAGAAAGTAGTTGCAGAAAACCCATCTGATGATGTTATAAGTCCAGTGAATGAAACCAAAAGTATTGACAGTGATGTGGAGATGAAGGATGCTTCTCCTGATACCATTGATAGCTCACAACCAGCTGATACTAAGCGAAAGAATGAAGAGCCTACAAAAGATAAAACATCTTTAGAAGTTTTTTCTCTGGATTCTGATGATGAAAATACTGAGACAGCAAATATATCAGTGGATGTGGAAAAGAAATCTTCAGTAGAATGTATTGTCAGTGAAATTAAACCTAAAACTAGACCTAAAAAGGATATTGAAGAAAAACACGTGAAACCTGGTGAAAAGTGTATTAATCCCACATGCATGCAATCTAATGATCTTCAACCATGCCCTCTATATCTACCTAGTGTTTACCGTGCTAGAGATACCCCAAACAATCCAAAAGCTTGCAAAAAGTGTATAGAAGAAGGCATATCTCTCATGGAAAAGCTGTCTTCAAGGTTGAGAGCAGGATATTGTTTGTTGGATGTGGAAATTCCAAGTAGTCAAGACTTGGTAGAAATATCTGATTCAGATTCAGAGGATGACTCTAAAAATACTAATCAAAGATTAATAAATGGTGGATGGAGGAAAAAGGGTCTCCCTAAACCTACAGCTGAAGAATTAATCAAAGATGTAGAGAAAGATTATATAAACCAAGTGTTGCCTGATCTATTCACCAAGGTCTGGTGCAAATTTGACGTTGATAAACAAATACAGTCATGTGAGGAAAGTCTTGTAAAAAAGATGAATATTTTGGATGATGAGTGCGCCAACTTGGAGAAACTAATAAATCAAGAACAAGTGCAATTGGATATGATTCGAACAAAGTTATATGAAACATTTAGGTACCCTACCGAGTGCAAGACTGAAGTCATAATTACAGAAAATGGAGATCATACCGAAGAGAACTCATTAGTTCCAGAAAGAAGATCAGTCCGTCTCAAAAAACAATTCCAACTTAATAAGCCTCCTGAGGTCTTGCCACCTGCCACTATGGAAGGACCACCATGTACAGCAGACAGTGTCGTTGTCAATAATATACAAGAATTTGCTGTGTCCTTGGAAAGTTTACCGTCCAAAGGAAGACTTCCAGATTATGCACTAAATGTTGGGGACAAAGTTTACGCTGTTCGACAGTCTATATTTGGTGCCTGGTGTTTAGCACAAATTGTCCGTGTTATGCCAAGAGGCACTAAGTTGGCAAATGGAACATTATCCCAATTTTCTCTGGTAACTGTTTACTTTGTGCAAGGTGGTGAAGGTGAGCAAGTGACTAAACAGGTTACTGGCAGACAGGTGGCGTATGCAACACCTTCTACAGTTATGTATAGTGTTGGAACTCGTATAATAGCTCTGTTTCAAAACAAACAGCAACTTAAAGAAGCTTATTACTCTGGGGTGATAGCAGAAATACCTGTTAAGGCAAACCGATTCAGGTATTTAGTTTTCTTCGATGATGGATATTCAAGATACGTGTATCATAAATTTATCTTGTTGGTTTGTCAACGTTCTAATCATGCTTGGGAAGATATACATCCAGTTTCTAGGGGCTTTATACGAAAATATCTGGAAGGCTTTCCAAACCAACCCATGGTGAGGGTGCAAGCGGGACAGTCTATCAGGGCTGAATATAAAGGCAAATTCTTGATGGCTTCAGTAGTGGCTGTAGATTCATCGTTAGCTCTTATTAAATTCAATGAAAACAGTGGCGCTCCAGCTAATCATGAAGAATGGATCTATAGAGGAAGCACTAGATTGGAGCCTCTTTTCCTTGAGTTGCAGGCCGCTGACAGAAAATCACACGGAAGGCACAGGCCCTCCTATGCTACTACAAATCTTAATAAGAGTAAACATTTCCCTTATGTGGAATATTCTAGACCCGATCAGAGTGAAGGAGACAACGCCAGTAATGCTACAGAATCTCAGTCAAATTTGCCACCTCCAAGCCCTGCAAAGGAAACTAAGGAGCAGACATCTGGTACAAGAGCAGTAGCCAAGAAGAGTACATCAAATAAAGATGATTCCTCCAAATATAAAGACAAAGATGAGGTACCTGCTAGCACACAGCAGATGCATGCAGATCAAGTTAAAAGTAAAGTTGTGTATTACTCCCCAAAAGTTACAATTAAGCCTAAGAAGCTTACACCACATACATGTGGTCCAGACTGCCTGAACAAGGATGCTATTGCTTTAAGGGAACTTAGAAATTACAATCCATTAGCAAGACCACTTCTTTCAGGATGGCAAAGACTGATCATAAAGTTTCGTGGTAAGAGGACTATTATGTATCACGCTCCTTGTGGACGCCGACTTCGCAATGCCAAAGAGTTACATCTCTACTTGAGACTGACACGCTCTCAGATGAGTGTTGATTTGTTTGATTTTGATCATTGGGTGCATTGTCTAGCTGAGTTTGTGCCGACCAAGTGCTTTGTCAGTAAAAAGGATTTGTCTCATGGAGTGGAGGCTGTCCCTGTGCCTTGTGTTAACTATTATGATAATGCTCTACCAGAATTCAGTGCTTACAGCACTCGACGTATTCCCACACGAGGTGTGAATCTTAATTTAGATGAGGAATTCCTATGTGGATGTGACTGTACAGATGATTGCCAAGACAGGAATAAATGTCAATGTTGGCAGTTGACATTAGAAGGAGCATCAGTTATTGGCAGCCAATTGAGTCGTGTTGGTTACCAATACAAAAGGCTATTGGAACCAGTACCTACGGGAATATACGAGTGTAATTCTAGGTGTAAGTGTGCTGCAACATGTCTCAATAGAGTAGTTCAACATCCTTTACAATTAAAGTTACAGGTATTTAAAACATTTAATCGTGGTTGGGGAATCAGAGCTTTGAATGATGTTTCTAAAGGAACATTCATTTGTATATATGCTGGAAACTTGCTCACAGATGCTGTCGCCAATGTGGATGGAGTTACAGAAGGAGATGAATATTTAGCAGAATTGGATTATATTGAAGTAGTTGAAAAGTTGAAAGAGAATTATGAATCAGATGTACCTGAAGAAGATAAGGATTTCGATGAGGAATCTGAAGAGCCATCAGACAATGAAAAGATATCAGATGCAGGAAAGGAAAAGAAGACTGGACCACACGGAGAATCAGATGAGGAGTTTAAACCTCACACAAAAATAGATTCAGGAGATGTAACGGGGATAGCTACACGAAGACAGTTACGGAAGAAGAAAAGTGATAGAAATGCCAAAAATAGCAAAGATTCAAAAGTGCTAGAGAGTACGGAAGAGAAAGTTGAGAAAGAAAAGGAGAAGGAACACAGTAAAATTGAGACTGCAGAGAAGAATAGTGGATGGGAGGATGAGGGAGCTGTGCCTGTGGTAGACGAATTCATCACCATCAGTGATGATGAGGAAAAAAGGGAACCTTCCAGGTTTGCTGCTCCAGATGACTTGAATGATGATGACAAGTATGTTTCTAAGCACAGgtcagttagaagcttctttggaaaagatgaggcctgctatattatggatgcaaaggttcaaggaaacctcggcagatatttaaatCATTCATGTTCTCCAAATGTATTTGTGCAAAATGTGTTTGTTGATACCCACGATCCACGCTTCCCTTGGGTTGCATTCTTTACTCTGAATCATGTACGAGCTGGAACAGAACTGACTTGGAACTATAACTATGATGTTGGAAGTGTTCCCGGAAAAGTGATGTTTTGTAGGTGTGGAGCTACCAACTGCAGGGGGCGTCTGTTATAA
- Protein Sequence
- MDSSNSTLSPSIDEKSILGGVSAEDMQGNEKSESPSNEKNVIQSLNSNINENILMDTIEFDEKNVTTSHNNSEEFESMTEAFKAAISEKSPSKSDVVNAAETKAAFPAFDSFDEDSCNKFDDLENRVLGILSDISREEQENSKQETNEQDAEDNVSVNETTSATISKIPEKKIEDTDDVSVDCDNDGDTLGLLAETEGRERHFSDPEDEDDEEEGDGDGDIEMEEEHLESGMDSDVGEGDDEEGEYSNSNDGDDDYKPKSDEEEDEQDDEEEDDNDPELRTYVKRKKLLKDLHRHTYQPSDSNDTMESQTPFQTDMDTAESRTSDVEPGEIMFSSVKEDTNSFSVNDKPVLSICSVSSLVGSLQDSHSEDNKRETETLNLGSDVSKVLDGETLHLKDYASQEDSANIISKDVSEEIIIEEDNSKNISMTISTDISTNIVPQILSTQSKNEVTKMSQEQDEPLVKVKESISVNDSPKDNLESAKENLEKYSQLMDVDEDIVSEETKDAIKSDKLLEKDSSTQKKDDSTKSSAEIIEQLSDTYNEKKVVAENPSDDVISPVNETKSIDSDVEMKDASPDTIDSSQPADTKRKNEEPTKDKTSLEVFSLDSDDENTETANISVDVEKKSSVECIVSEIKPKTRPKKDIEEKHVKPGEKCINPTCMQSNDLQPCPLYLPSVYRARDTPNNPKACKKCIEEGISLMEKLSSRLRAGYCLLDVEIPSSQDLVEISDSDSEDDSKNTNQRLINGGWRKKGLPKPTAEELIKDVEKDYINQVLPDLFTKVWCKFDVDKQIQSCEESLVKKMNILDDECANLEKLINQEQVQLDMIRTKLYETFRYPTECKTEVIITENGDHTEENSLVPERRSVRLKKQFQLNKPPEVLPPATMEGPPCTADSVVVNNIQEFAVSLESLPSKGRLPDYALNVGDKVYAVRQSIFGAWCLAQIVRVMPRGTKLANGTLSQFSLVTVYFVQGGEGEQVTKQVTGRQVAYATPSTVMYSVGTRIIALFQNKQQLKEAYYSGVIAEIPVKANRFRYLVFFDDGYSRYVYHKFILLVCQRSNHAWEDIHPVSRGFIRKYLEGFPNQPMVRVQAGQSIRAEYKGKFLMASVVAVDSSLALIKFNENSGAPANHEEWIYRGSTRLEPLFLELQAADRKSHGRHRPSYATTNLNKSKHFPYVEYSRPDQSEGDNASNATESQSNLPPPSPAKETKEQTSGTRAVAKKSTSNKDDSSKYKDKDEVPASTQQMHADQVKSKVVYYSPKVTIKPKKLTPHTCGPDCLNKDAIALRELRNYNPLARPLLSGWQRLIIKFRGKRTIMYHAPCGRRLRNAKELHLYLRLTRSQMSVDLFDFDHWVHCLAEFVPTKCFVSKKDLSHGVEAVPVPCVNYYDNALPEFSAYSTRRIPTRGVNLNLDEEFLCGCDCTDDCQDRNKCQCWQLTLEGASVIGSQLSRVGYQYKRLLEPVPTGIYECNSRCKCAATCLNRVVQHPLQLKLQVFKTFNRGWGIRALNDVSKGTFICIYAGNLLTDAVANVDGVTEGDEYLAELDYIEVVEKLKENYESDVPEEDKDFDEESEEPSDNEKISDAGKEKKTGPHGESDEEFKPHTKIDSGDVTGIATRRQLRKKKSDRNAKNSKDSKVLESTEEKVEKEKEKEHSKIETAEKNSGWEDEGAVPVVDEFITISDDEEKREPSRFAAPDDLNDDDKYVSKHRSVRSFFGKDEACYIMDAKVQGNLGRYLNHSCSPNVFVQNVFVDTHDPRFPWVAFFTLNHVRAGTELTWNYNYDVGSVPGKVMFCRCGATNCRGRLL
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -