Alep017062.1


Basic Information
Transcription Factor Domain
Sequence Information
Similar Transcription Factors

Basic Information

Insect
Athetis lepigone
Gene Symbol
Rfx2_1
Assembly
GCA_033675125.1
Location
CM066229.1:2973031-3003066[-]

Transcription Factor Domain

TF Family
RFX
Domain
RFX domain
PFAM
PF02257
TF Group
Basic Domians group
Description
RFX is a regulatory factor which binds to the X box of MHC class II genes and is essential for their expression. The DNA-binding domain of RFX is the central domain of the protein and binds ssDNA as either a monomer or homodimer [1]. It recognize X-boxes (DNA of the sequence 5'-GTNRCC(0-3N)RGYAAC-3', where N is any nucleotide, R is a purine and Y is a pyrimidine) using a highly conserved 76-residue DNA-binding domain (DBD) [2].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.1 2.1e+03 0.5 0.0 3 17 282 296 281 308 0.87
2 8 1.8 3.7e+04 -3.5 0.0 6 17 331 342 329 345 0.84
3 8 1.8 3.7e+04 -3.5 0.0 6 17 377 388 375 391 0.84
4 8 1.8 3.7e+04 -3.5 0.0 6 17 423 434 421 437 0.84
5 8 1.8 3.7e+04 -3.5 0.0 6 17 469 480 467 483 0.84
6 8 1.8 3.7e+04 -3.5 0.0 6 17 515 526 513 529 0.84
7 8 5.4e-36 1.1e-31 110.4 0.1 5 78 560 633 556 634 0.97
8 8 2 4.1e+04 -4.2 0.3 26 46 918 939 907 942 0.69

Sequence Information

Coding Sequence
ATGTCTGAGATGGGCTTTGAGAATGTGTTCTATTTAGAGAACTTTGAGTGCGCCGGCGACGAGGTTCTGGTGGAGTCATCGCCGCCTGCCTCCCCGGACATGGCGGCGCGGCTCGCGGCCCCGGCACAGGGTGGCGCGGGCGGCGGTGCCTCGCCGAGCGCCGTGCGTGAGCTCATCGTAATACCGGAAATACCCGACTCCATGCATTTGCAGCACGCTATGCAACAGGTGTCCAGTACGGTGGTGGAGGTGAACGGCGACAGTTCCGGCCACTCCAGCCCCACAGCAGAGGGCCAGCACACTTACATCACCGTGTCCAGTGAATGTACGTACAATTATGAGACGTCCTTTAGCTCTGTAAAGTGGGGTGGGGTGGGACAGAGACAGAGTAATACGTTAGACAGAGATGAAAACATGAGATTGGTAATCGGGATGTTTTGCCGGGAAGTGAGGTCCAGCGGCGAGTTGCCTGGGAGATCTCCAAGAGCATGGAGGTGCCTCGGTATCGGTCCTATTACCCCTGTGAGTGACTTCCTCCTGGTCTTTGTGTACCCAAGCTCAAGTGAGGGCGGGAATGGTGTCAACTACCATGTGCAATATGTTACGGAGCCGCAAGAGATCTACACACAAGGACATCCGACACATATGGATTCCTTGCGCTCATACCCTGTGTACGGAGTGACGACTGTGGGCAATGGTACCACTGCGGAGGGAACATCTGCCGACAACGGCTGGGGCGGAGCCTCTTCTGCCGAATACACAGCTTACGGCGTTGTGGTGGCCGGCGACGAAGCATCCGCGCCGGCGTCGCCGGCCACGCCGGCCGCGCCGCGCATGCCGCCGGCCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTCGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTCGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTCGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTCGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTTGACCACTACGAGACCGCTGAGGGTGAGTCAAGTGAGGAACTATCTACTACTCTTTACTACTATAAGGCATCCGCACTGGTGTCGCCGGCACCGTGCAGTGGCTGCTCGACCACTACGAGACCGCTGAGGTGGCTGCTCGACCACTACGAGACTGCTGAGGGCGTATCACTTCCTCGCTCCACACTATACGCGCACTACCTCCGCCACTGCGCTACCCATCGCCTAGAACCAGTCAACGCAGCGTCCTTCGGCAAGCTCATCCGCTCAGTTTTCATAGGCCTTCGGACTAGGAGACTGGGGACTAGAGGCAACTCAAAGTACCACTACTACGGCATCAGGGCCAAGCCCGGCGTGGAACACGAGAACAGTCAGAGCGACGATATGAATGATCAGCACGATAATGTGGATGATAAGACTGATGTGCTGGATCAGCAGGAGGGTAGATCGCGTGACCGTTCGCGCGAGCCGAGCAGCCCGAACCACGCGCACCGGCAGTACTTAGGCACGGTGTCGCCGCCCGAGCCGCCGCCGCTCACCATACACCCGCTGCCGGACGATGTCACGCTCGAGTCGCTCAACGCGCTGCGGAGACACCACAGGGAGCACGGCGCGGAGTTCCTGTCGGCGGTGGCGGCGCTGGACGCGGGCGCGGTGGAGCGCGCTCGGAGGGCCTTCTGGCGGCGCGCGCCCGACCTGCCGCGCCGCGACCTGTGCCGCCTCACCGCGCGCCGCGACGTGGCCGCCTGGCTGCGCGCCGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACACAGGTACGTGTGCACGTGTGCACGTGTGCACGTGTGCACAGTGTGCCTCAGTGCGCGACTGTGCCGCCTCACCGCGCGCCGCGACGTGGCCGCCTGGCTGCGCGCCGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACACAGGTACGTGTGCACGTGTGCACGTGTGCACGTGTGCACAGTGTGCCTCAGTGCGCGACTGTGCCGCCTCACCGCGCGCCGCGACGTGGCCGCCTGGCTGCGCGCCGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACACAGGTACGTGTGCACGTGTGCACGTGTGCACGTGTGCACAGTGTGCCTCAGTGCGCGACTGTGCCGCCTCACCGCGCGCCGCGACGTGGCCGCCTGGCTGCGCGCCGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACACAGGTACGTGTGCACGTGTGCACGTGTGCACGTGTGCACAGTGTGCCTCAGTGCGCGACTGTGCCGCCTCACCGCGCGCCGCGACGTGGCCGCCTGGCTGCGCGCCGCCGAGCTGCAGCTGTACCAGCGCGCCGTGGAGCTGCTGCTGCCCGACGTGCTGCGCCCCATCCCGCCGCAGCTCACACAGGTACGTGTGCACGTGTGCACGTGTGCACGTGTGCACAGTGTGCCTCAGTGCGCGACTGTGCCGCCTCACCGCGCGCCGCGACGTGTGCCTTAACTACTAGACTCTCATCAAtcGCGATCCGCAACTTCGCGAAGAGCCTGGAAGGCGCGCTGGCggccggcgcgggcggcgcgcccACAGCGGCGGCGCGAGCCCAGGCCGCGGCGGCGTCGGCGCTGGCGGCGGCACTACGTCGCTACACGTCGCTCAACCACCTCGCGCAGGCCGCGCGCGCCGTGCTCAACAACCACCATCAGATACACCAGATGCTACAGGACCTGAACCGCGTGGACTTCCGCGTGGTGCGCGAGCAGGCCGCCTGGGCGTGCTCCTGTGGCAGCGCCGCCACCGCACACAGGCTGGAAGCAGACTTCAAGGCGACGCTGGGGCGCGGCGCGTCGCTGGAGCAGTGGGCGGGCTGGCTGGAGGGCTGCGTGCGCGGCGCGCTGCAGCCGCACGAGCGCCGCGCCGACTACACCGCGCGCGCCAGGCGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTACACACAGTACATATATACTCAGCCGCACTACACGACTGCTGCTCGACTGGAGCTTCTACTCCTCGCTCGTCATCCGCGAGCTCACGCTCAGGTCTGCGGCGTCGTTCGGCTCGTTTCACCTGATCCGGCTGCTGTACGACGAGTACGTGTCGTACCTCATCGAGCGCCGCGTGGCCGCGCACCACAACGCGCCGCCCATCGCCGTCATGCACCGCGCTCTTTGGTCGGAGGAAGCTGAAACAGCTTTTATTACCTTAAAGAACGCCTTGGTTACTGCCCCGGTTTTAGCTGTCCCTGATTTTGACAAACCTTTCACTGTTCATTGTGACGCTTCAGCGTATGGTTTAGGTGGTATGTTGTCACAAACAATAGACAATTACGAACATCCGATTGCGTACGTTAGCCGTTCGCTGAACAAAGCGGAGCGGAATTATAGTGCTACCGAACGGGAGGCACTGGCGGTTATTTTTGCAGTAGAGAAATTTCAAGCTTATTTAGGTTCCCGACCCTTCAAAGTGGTCACGGATCACTCATCGCTGAAGTGGTTCATGAACTTGGAGAATCCAACCGGAAGACTTGCTCGTTGGGGTTGCCGACTGTctcaatttgactttgaaattgAGCACAGGAAGGGCTCTGACAACGTCGTTCCGGATGCATTGTCCAGGCTTATGAAAGTGGAAGCGGTGAATGATTCCGATGACGCAGAGAAAGATGATTGGTATGACAGGACCTTTAATGGTTGTAAAGCCTTTCCTAAAAACTTTCCTAATTTCTGCGTCAAGGACGGGAAACTCTATCGTTTCTGCAAGAGTAAATACAATCTACTGAGTGAATTTGATTGGAAGGAAGTGGTAAAGAAAGATAACGGAGTGCAATTCACGGGATCGGAATTCCGGAATCTACTGAAACGCTACAACATTCCCAAACTACATTATTGCCCACGTTATACGCCGCAGGTTAATCTGGTAGAACGGTATAACAAGACAGTTATGACGGCCGTAGCTTCCTACGTGGAAGAAAACCATAGGAACTGGGATGAGCAACTGTACCGAATTCAGTTTGCTATAAACAGTGCAGTAAACGAGTCCACTGGGTTTTCTCCTTTCTTTTTAGTACATGGTAGGGAACCGGTCGTGAATGGGTCCTTCTACAGAGATACTGATGCGGAGTATGAAGTAGCCATGCCTCGCGACGAGTACGCTGGGGAGTTAGGCTGTTTGAGGGACATTTTTGGTCAGGTTCGGTTGCATTTGTTAAAGGCACATGAGGCTAactctaaatattataatttacgccGTAGACCGGCTAAGTTTTCAGTTGGGGATATTGTTTGGAAGCGCTGCTATACGCAAAGCGATGCAGCTAAGTTTAAAATGGCTAAGTTAGCACCCAAGTACGAGAAGTGCAGGGTGAAGGCCGTTTTGTCCCCCTTAGTTTACGAATTGGAAAGATTAGATGGCCATCCCATTGGGTCTTGGCACATGAAGGACTTGAAGAGTCACTAG
Protein Sequence
MSEMGFENVFYLENFECAGDEVLVESSPPASPDMAARLAAPAQGGAGGGASPSAVRELIVIPEIPDSMHLQHAMQQVSSTVVEVNGDSSGHSSPTAEGQHTYITVSSECTYNYETSFSSVKWGGVGQRQSNTLDRDENMRLVIGMFCREVRSSGELPGRSPRAWRCLGIGPITPVSDFLLVFVYPSSSEGGNGVNYHVQYVTEPQEIYTQGHPTHMDSLRSYPVYGVTTVGNGTTAEGTSADNGWGGASSAEYTAYGVVVAGDEASAPASPATPAAPRMPPATVQWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGESSEELSTTLYYYKASALVSPAPCSGCSTTTRPLRWLLDHYETAEGVSLPRSTLYAHYLRHCATHRLEPVNAASFGKLIRSVFIGLRTRRLGTRGNSKYHYYGIRAKPGVEHENSQSDDMNDQHDNVDDKTDVLDQQEGRSRDRSREPSSPNHAHRQYLGTVSPPEPPPLTIHPLPDDVTLESLNALRRHHREHGAEFLSAVAALDAGAVERARRAFWRRAPDLPRRDLCRLTARRDVAAWLRAAELQLYQRAVELLLPDVLRPIPPQLTQVRVHVCTCARVHSVPQCATVPPHRAPRRGRLAARRRAAAVPARRGAAAARRAAPHPAAAHTGTCARVHVCTCAQCASVRDCAASPRAATWPPGCAPPSCSCTSAPWSCCCPTCCAPSRRSSHRYVCTCARVHVCTVCLSARLCRLTARRDVAAWLRAAELQLYQRAVELLLPDVLRPIPPQLTQVRVHVCTCARVHSVPQCATVPPHRAPRRGRLAARRRAAAVPARRGAAAARRAAPHPAAAHTGTCARVHVCTCAQCASVRDCAASPRAATCALTTRLSSIAIRNFAKSLEGALAAGAGGAPTAAARAQAAAASALAAALRRYTSLNHLAQAARAVLNNHHQIHQMLQDLNRVDFRVVREQAAWACSCGSAATAHRLEADFKATLGRGASLEQWAGWLEGCVRGALQPHERRADYTARARRLLLDWSFYSSLVIRELTLRYTQYIYTQPHYTTAARLELLLLARHPRAHAQVHTVHIYSAALHDCCSTGASTPRSSSASSRSGTHSTYILSRTTRLLLDWSFYSSLVIRELTLRYTQYIYTQPHYTTAARLELLLLARHPRAHAQVHTVHIYSAALHDCCSTGASTPRSSSASSRSGTHSTYILSRTTRLLLDWSFYSSLVIRELTLRYTQYIYTQPHYTTAARLELLLLARHPRAHAQVHTVHIYSAALHDCCSTGASTPRSSSASSRSGTHSTYILSRTTRLLLDWSFYSSLVIRELTLRSAASFGSFHLIRLLYDEYVSYLIERRVAAHHNAPPIAVMHRALWSEEAETAFITLKNALVTAPVLAVPDFDKPFTVHCDASAYGLGGMLSQTIDNYEHPIAYVSRSLNKAERNYSATEREALAVIFAVEKFQAYLGSRPFKVVTDHSSLKWFMNLENPTGRLARWGCRLSQFDFEIEHRKGSDNVVPDALSRLMKVEAVNDSDDAEKDDWYDRTFNGCKAFPKNFPNFCVKDGKLYRFCKSKYNLLSEFDWKEVVKKDNGVQFTGSEFRNLLKRYNIPKLHYCPRYTPQVNLVERYNKTVMTAVASYVEENHRNWDEQLYRIQFAINSAVNESTGFSPFFLVHGREPVVNGSFYRDTDAEYEVAMPRDEYAGELGCLRDIFGQVRLHLLKAHEANSKYYNLRRRPAKFSVGDIVWKRCYTQSDAAKFKMAKLAPKYEKCRVKAVLSPLVYELERLDGHPIGSWHMKDLKSH

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-