Basic Information

Gene Symbol
Prdm15
Assembly
GCA_963932425.1
Location
OZ010627.1:1870565-1874757[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 14 2 1.7e+02 3.0 0.3 2 23 239 260 238 260 0.94
2 14 0.16 13 6.5 5.1 3 23 269 290 267 290 0.95
3 14 1.8e-05 0.0015 18.9 0.7 2 23 448 469 447 469 0.97
4 14 0.014 1.1 9.8 0.5 1 20 473 492 473 494 0.94
5 14 9.2e-06 0.00077 19.8 1.5 1 23 502 524 502 524 0.98
6 14 0.0072 0.6 10.7 0.9 3 21 530 548 529 549 0.93
7 14 0.0002 0.016 15.6 6.9 1 23 553 575 553 575 0.97
8 14 0.00015 0.012 16.0 0.2 3 23 596 616 594 616 0.95
9 14 0.0075 0.62 10.7 0.8 1 23 621 643 621 643 0.96
10 14 0.00023 0.019 15.4 0.1 2 23 649 670 648 670 0.96
11 14 0.00081 0.067 13.7 8.3 1 23 675 698 675 698 0.96
12 14 3.1e-06 0.00026 21.3 3.5 1 23 704 726 704 726 0.98
13 14 0.00087 0.072 13.6 3.0 1 23 732 755 732 755 0.94
14 14 0.056 4.7 7.9 4.9 1 23 760 783 760 783 0.95

Sequence Information

Coding Sequence
ATGAGTTCACCTAATGCGGAGGAGAATTCGTACAGCGAGATTGAAGTCAGCTTGTCAGCCTGCAGCGTTTGCGGACAGCAACATGATACAATTACTTGTCCTTTTTTATTGGACCTTCACTATATCAAAGATACTCCGGTATTATCGAGAGCTAGACAAACAATACCTAAGAACCTAGAGATCACAAGAATGGCTGATGGTTCAACGACTGTTATCGCGAGGATAGAATTACCCAGAGGAACAACATTTGGCCCTCTGTACGCCAAGCGTATATGGACAATGAATCCACTGACTCACTTTCCCATCAGGGTCTTTGGGAACTCTGCCTGCGAAACTTACCATCTAGATTATTCAAACGAGGATAATTCAAACTGGATGTGTTTTGTCGAGCCAGCATCGAATGCCAAAGAGCAGAACTTAATATGCTATCAGGTGAAACAGGACATATTTTATACCGCGATGCGTACCATTCCTGTAGGTGAAGAATTGAGAGTTTGGTATGCACCAAACTATGCTTTGAAGATGAAGATGCCTGTCTTCAACAGTGATTTTGCAAACTTGAGCGCAACCATTCCGGAGCCAGAAATCCAACAGATAATAAAAACAGAATCCAACAAAGATCAACCTGGACTTCTGAaTAAGGACGTAGCTCAAGAATTGGCAGAGAAATTACCGGCTCAGCGGTTGGGAGCAAGGGATGACAAGGTGACGTGGAATTGTCGGATTTGTTCCACCGTTATATGCTCTGTTGTTTTGTATGCCAAGCACTTGATGGAACACTATAAGCCATTGATCGGCGTACATTGCACCatatgtaacaaaaaatgCAACAATATGAcaGCTCTTGGGAGGCACAAAAATTCTAAGCATCCCGAAGACTCATCGAATGACAGTGTCGTTGGAATACCGACATCGGAGAGCCAACAGCAACAAAATGCACAAACGATTTTTTTGAACATCAGCGACGCCGGCGGACAGACATCAGATGCAATGAAAGATATATTGGAGAAATTCAAGGCTGGAAAGGCAATTACAGAGAGTAGTTTGCTGTCAACGTCTTCCATCGAAAAAGAGAATCACCCAGATCTTCCTCTGTTGGACACAAATTCAATTAACGTCAATGATCTACTCCAAAATAATAGTTCCCTCATAGAAAACTCATCCCTGAAATCCATCCTAGAGAATCAATGTCTCAACATGAACTTGGGTTTGAGCGATTCCATGCTCTCGGAAAACATTTCTACACCAGATTCTGTAAAATTCAATGTCGAGGAGCTGGCATCGGAACTTTTGGACATCGTCCCCGATGTGGACAATATAAACAAAAGAATCGATAATCTGGAGTGCGATATTTGTGATaagaaatttgacaaaattgacTACCTGTACCGTCACCTACGAAAACACACCGGTGAATTCATCTGCCCCTCTTGTCTCGCGGTCTTTGCAAGAAAGGAAAACCTCCTGTCACACACATGCTTCTCTCAAAAATTGGATTACCATTACGAATGCCCCTATTGTCAAAAACCGttcatgttgaaaaaatatttaaggaGACACATGGTGAAGCACACAGAATGGAACAACTGCAAGTGGTGCCATGCTCCATTTTCCTCTCCAACGGAGTTGGAAGCCCACAAATGTTCGACGCCGAAACACGAGTGTCTACAATGTAACAAACGCTTCGTTCACAGAGCTCACTTGAACCGCCATCTGAAGTTACACGAAGACCCAAAGCCGGCGGTCAAACGGGTGCGGAAAAAACAGCTGGATAAACCTGTAATCTGTGAAAAATGTGGCGATGTTTTTAAAACTCCATACAGCTTGAAGCAGCACCTCAGTTTGCATGGAGAGAGAACTTTCGAATGCGATATTTGCCAAAGAAGATTCCATCGCATCGGAGTGCTAAAAGAGCATAAGGCGATACATCAAGCGGCCCAAATACCCTGCAACGTATGtggaaagaaattgaagagtAAAAAGGCTCTGGATATCCACATGCTGTTGCACGGGAATAAAAAGCACCAGTGCGACAAGTGCGATAAAagtttttttcaaaagtgcAACTATCGCAAGCACTACAATCAAGTGCATGGGGAAAAATCAATGTACAAATGCACCCACTGCCCCACACAGTTCACGAGCAAAGCTAACTTTAACAGACACATCGAAAGCCACGTGAAACCTGCTCAATTCACGTGTGCGTCCTGCCCCAAGTCATTTCACAAAGAATACCAACTCAAACGTCATACTCAGGCGAGTCACAGTGGAATTGTCTTTCGTTGTCCGTATTGTCAAATGGCTGCGAGGCACAGACATAGTATGCGAAGGCATTTCGAGAGGCAACACAGTGACCTGAGAGAGGCGTGGGACAGACCAGGATTCGTTAATCAATTATCGGAGAAAGCTCCGCCCCTACCGATAGACCCGGCAATCACGGAGTCTGATAAACTCGTTCAAGTTAGCTACCAAGATATGAGTAATAAGAATTTCGAAGATACGGACCACGCACAAGaTAAAGCTATGCTTTTATCCGCGACAGgaatggaagaaaatgaatatttgcAAGCACCTCAAGTCGATGCCGCGACTCACCTCAACGACGGTCAAGTCAATTGCAATTCATTAAATGGACATGAAATTCTTCTGCAAGTAGCGGGAATCGAGCAGGCTGGGAGTATGGAAAGTTCAGATTTGTCATTGACGGAAGTACCGCAACTCAGTATAAGCGAATCTGACGCTCGCCTTGCAGAGTCTGTTCTCGGGAATGCTTATATATTCGGAGAAGACGGGGGAGACATAATGTTCTATGTACTGGATAACACACCGATAATTTCCGAGTACTAG
Protein Sequence
MSSPNAEENSYSEIEVSLSACSVCGQQHDTITCPFLLDLHYIKDTPVLSRARQTIPKNLEITRMADGSTTVIARIELPRGTTFGPLYAKRIWTMNPLTHFPIRVFGNSACETYHLDYSNEDNSNWMCFVEPASNAKEQNLICYQVKQDIFYTAMRTIPVGEELRVWYAPNYALKMKMPVFNSDFANLSATIPEPEIQQIIKTESNKDQPGLLNKDVAQELAEKLPAQRLGARDDKVTWNCRICSTVICSVVLYAKHLMEHYKPLIGVHCTICNKKCNNMTALGRHKNSKHPEDSSNDSVVGIPTSESQQQQNAQTIFLNISDAGGQTSDAMKDILEKFKAGKAITESSLLSTSSIEKENHPDLPLLDTNSINVNDLLQNNSSLIENSSLKSILENQCLNMNLGLSDSMLSENISTPDSVKFNVEELASELLDIVPDVDNINKRIDNLECDICDKKFDKIDYLYRHLRKHTGEFICPSCLAVFARKENLLSHTCFSQKLDYHYECPYCQKPFMLKKYLRRHMVKHTEWNNCKWCHAPFSSPTELEAHKCSTPKHECLQCNKRFVHRAHLNRHLKLHEDPKPAVKRVRKKQLDKPVICEKCGDVFKTPYSLKQHLSLHGERTFECDICQRRFHRIGVLKEHKAIHQAAQIPCNVCGKKLKSKKALDIHMLLHGNKKHQCDKCDKSFFQKCNYRKHYNQVHGEKSMYKCTHCPTQFTSKANFNRHIESHVKPAQFTCASCPKSFHKEYQLKRHTQASHSGIVFRCPYCQMAARHRHSMRRHFERQHSDLREAWDRPGFVNQLSEKAPPLPIDPAITESDKLVQVSYQDMSNKNFEDTDHAQDKAMLLSATGMEENEYLQAPQVDAATHLNDGQVNCNSLNGHEILLQVAGIEQAGSMESSDLSLTEVPQLSISESDARLAESVLGNAYIFGEDGGDIMFYVLDNTPIISEY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_01200421;
90% Identity
iTF_00175932;
80% Identity
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