Basic Information

Gene Symbol
-
Assembly
GCA_963978495.1
Location
OZ021698.1:33995104-33998486[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 21 0.0054 0.57 11.2 2.0 1 23 52 74 52 74 0.95
2 21 3e-07 3.2e-05 24.6 2.3 2 23 81 102 81 102 0.98
3 21 1.8e-06 0.00019 22.2 5.7 1 23 131 153 131 153 0.98
4 21 0.00022 0.024 15.5 4.4 2 23 159 180 158 180 0.97
5 21 0.015 1.6 9.8 0.0 1 23 185 207 185 207 0.98
6 21 5.7e-07 6.1e-05 23.7 0.7 1 23 215 237 215 237 0.98
7 21 0.13 14 6.8 3.5 3 23 245 266 243 266 0.93
8 21 0.00024 0.026 15.4 0.3 3 23 279 299 277 299 0.96
9 21 1.5e-06 0.00016 22.4 2.6 1 23 305 327 305 327 0.96
10 21 3.8e-08 4.1e-06 27.4 0.2 1 23 333 355 333 355 0.98
11 21 2.8e-07 3e-05 24.7 0.9 1 23 361 383 361 383 0.98
12 21 0.0018 0.2 12.7 2.6 1 22 389 410 389 414 0.94
13 21 4.2e-06 0.00045 21.0 1.3 3 23 581 601 579 601 0.97
14 21 0.00035 0.037 14.9 0.6 1 20 607 626 607 627 0.97
15 21 0.0018 0.19 12.7 2.7 1 23 635 658 635 658 0.96
16 21 1.4e-05 0.0015 19.3 1.3 1 23 665 688 665 688 0.97
17 21 2.5e-07 2.7e-05 24.8 1.1 1 23 694 716 694 716 0.98
18 21 0.00086 0.092 13.7 1.8 1 23 723 745 723 745 0.97
19 21 8.4e-06 0.0009 20.0 2.6 1 23 749 772 749 772 0.97
20 21 1.4e-05 0.0015 19.3 0.3 3 23 780 800 778 800 0.97
21 21 2.7e-07 2.9e-05 24.7 1.0 1 23 806 828 806 828 0.98

Sequence Information

Coding Sequence
ATGCTATCGAAGCTCGACCTGGTCAAGAACAAGAAACCGGATGAAGGTGCTCAGAAAGTTGGAACCGCTGACCAAACATCAAGCGGTGCAAACGCTCCTATAAAGGAAGAAttaaaagacgacgacgacgatgaagacgatatGCCCCTGGCTTACCACTGCAAGACCTGtgctgtatttttcaaaactaaagATCTGCTGAACAATCATGAAATCGAGCATaaggggaaaagaaagaatactTGCAACCAGTGCGGGAGAGTTTTTCGAACTTACGTTAATCTTAGAAAACATATGAAGAAGCATGCCggcaataaaaataagaacgaGAGTAGGGCGGTGGTGAATGTTGACCTACATGTGAAAACAGAGAAGAGCGGATATTCTGAGTTTGTTTGCAAAACTTGCAATAAAGTATTCCGTCACAAAAGCAATTATCAAAAACATTTGCTCAGGCATACCGCGGGCGACCTTACCTGCAATCATTGTCCGAAAAAGTTTCGTCTGTTTCGAGATCTCACTCGGCATGAAAAGACGCATTTTTATCCAAGCTACATGTGCAAAGAGTGTGATTACGAAACAACCGTTGTCGCAGCTCTTGGCATCCACATGCTGAGACATACAAACAAGTCCGATCTACCTTATAAGTGCAACGATTGCGATAAAAGTTTTCGTAAAGCTATCGAACTCCAAGAACACTACAATATTCATTCTGGAGAAAAGCCATCCATTTGCACCATTTGCGGCACCGCTTTCCACCTGAGGAGACAGTTATCCGCCCACTGCAGACGAACACATCCAGAAATGAAGGCGAGTAAAGTGACGAGCACAGCCTGTGACATTTGCGGACGGGTATTAGCAACGAAACGTTCATTATTCCGTCACAAAGAAAGCCACAATCCGACAAAATTGTACTTATGCGATTACTGCGGAAAGAGTTTGAGCAGTTCGGAGCACCTAAAGAAGCACCGAAGGATTCATACGGGGGAAAAACCCTACGTTTGCGATATCTGTGGCAAAGGATTTAcagattctgaaaatttgcgGATGCACAGACGCATTCATACCGGAGAAAAGCCCTACAAGTGCGATCAGTGTCCTAAGGCCTTCTCACAGAGATCGACACTCACTATTCATCGGCGTGGTCACACGGGAGAACGACCATATATATGCCAAATTTGTCATCGAGGATTCTCCTGCCAGGGGAATCTTACCGCACATCAAAAATCTACGTATGTTCATTATCGTAACGTCACCTTGATTTATGCTAGAGTACCTTCTTTGAGTTTGATGCCAGCAAGAAGACTTCCTCCTTACTATATCCACGGATATGATTGGGAAGGTGAAAACTCTGAGGGTTCGTCTACACTAGATGCCTGGGACTTTCCAATCCAAACCGACTACAAGAGACCTGTTGAAAGCCAGCATAATCGTAAAAGGGGCATGATTTGGCGCATCAAAGGGACGAAAAAGTACGTCCGGGCATTACGTACCAGCTTAGAAACAGTGAGCAAGAGTAAGGTTGAAAATGGAATGGGCAAAATATTTACTCCGATTAAAATTGTAAAGATCAAAAAGAAGGATGGAGAAGTTGTGACAAAAGATGCTGAGAAGCTGTGCACCAAACCATCCACAGTTCGTGTGGAGATTAAAAGTTTACAAGTAAAAGATGATGGAACTGATTCTGAAAGCGAGCCAACGGCCGCAGAACTTTTTGGCGACAACCCCAGTGATACTTTTTGCACAATATGCAACAGGGATTTCAAAACTAAAGGGGGGCTCTGGAAACACATGAGAAATCACAACACTCGAAAACCTTATAAATGTCCGCAGTGTCCTGCACGCTGTAGAAGTAAACAGGATCTTGAGAGACATCTTGTCTGTCATGATGACCAGATATTCTATTCCTGTGATATATGCTATATACGTTACAAATCAAAACAAGCATTGAAAAACCACCATATAAGACAACATGATGACAGCGAGGGTCAATTTAACTGCGAGAAGTGTGAtagaaagtttaaaataaaagGTGATCTCAGCTCGCATATGAGGGTTTACCACGGCGAGGGCACGGAATTCGTCTGTGAGGTTTGCGGCAAATCATTCAACCGTTCTAAAGGACTAATAGCCCATCAACGTCACCATAGGGTTAGCGTTTATAATTATCCATGCACAAAATGCAAGCGTAAATTCACTACAGATCTGAAACTTCAGAATCATTTACTCGAACACCAAAAAGGCTTCAAGTGCGAACAGTGTAACAAAGAGTTCAACCAGAAGTCACGTCTCCAGTATCACATGCTCATGACGCACGGTAATCCCGAACCCCAAATATGCTCCATATGTGGAAAGCTGTACAAAAGCAGCGGTAGCCTCCGAACTCACATCTTGACACATGCTGGAGAACGACCCTACAAGTGCGATGTTTGCGGAGAATCCTTCACTCAGAGATCAAGTATGATGCGACATAGACGGGGACACCCTGGAAGATTTTCCCCTCCCCCACCCATCCCCATCACGGAAATCATCAGAGATATCGAAGAAAAGGCTCATGCTTCAAATTAG
Protein Sequence
MLSKLDLVKNKKPDEGAQKVGTADQTSSGANAPIKEELKDDDDDEDDMPLAYHCKTCAVFFKTKDLLNNHEIEHKGKRKNTCNQCGRVFRTYVNLRKHMKKHAGNKNKNESRAVVNVDLHVKTEKSGYSEFVCKTCNKVFRHKSNYQKHLLRHTAGDLTCNHCPKKFRLFRDLTRHEKTHFYPSYMCKECDYETTVVAALGIHMLRHTNKSDLPYKCNDCDKSFRKAIELQEHYNIHSGEKPSICTICGTAFHLRRQLSAHCRRTHPEMKASKVTSTACDICGRVLATKRSLFRHKESHNPTKLYLCDYCGKSLSSSEHLKKHRRIHTGEKPYVCDICGKGFTDSENLRMHRRIHTGEKPYKCDQCPKAFSQRSTLTIHRRGHTGERPYICQICHRGFSCQGNLTAHQKSTYVHYRNVTLIYARVPSLSLMPARRLPPYYIHGYDWEGENSEGSSTLDAWDFPIQTDYKRPVESQHNRKRGMIWRIKGTKKYVRALRTSLETVSKSKVENGMGKIFTPIKIVKIKKKDGEVVTKDAEKLCTKPSTVRVEIKSLQVKDDGTDSESEPTAAELFGDNPSDTFCTICNRDFKTKGGLWKHMRNHNTRKPYKCPQCPARCRSKQDLERHLVCHDDQIFYSCDICYIRYKSKQALKNHHIRQHDDSEGQFNCEKCDRKFKIKGDLSSHMRVYHGEGTEFVCEVCGKSFNRSKGLIAHQRHHRVSVYNYPCTKCKRKFTTDLKLQNHLLEHQKGFKCEQCNKEFNQKSRLQYHMLMTHGNPEPQICSICGKLYKSSGSLRTHILTHAGERPYKCDVCGESFTQRSSMMRHRRGHPGRFSPPPPIPITEIIRDIEEKAHASN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00175222;
90% Identity
iTF_00175222;
80% Identity
-